The 2S albumin allergens of Arachis hypogaea, Ara h 2 and Ara h 6, are the major elicitors of anaphylaxis and can effectively desensitize peanut-allergic mice

Clinical and Experimental Allergy

Volumn 42, Issue 2, 2012, Pages 326-336

  Kulis, M ^a   Chen, X ^b   Lew, J ^a   Wang, Q ^b   Patel, O P ^b   Zhuang, Y ^b   Murray, K S ^c   Duncan, M W ^c   Porterfield, H S ^b   Burks, A W ^a   Dreskin, S C ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c Children's Hospital Colorado   (United States)

Author keywords

Ara h 2; Ara h 6; Desensitization; Food allergy; Human basophil assay; Immunotherapy; Mouse model; Peanut allergy

Indexed keywords

ARA H 1ALLERGEN; ARA H 2 ALLERGEN; ARA H 6 ALLERGEN; CHYMASE; FOOD ALLERGEN; HISTAMINE; IMMUNOGLOBULIN E; IMMUNOMODULATING AGENT; PEANUT EXTRACT; PLACEBO; UNCLASSIFIED DRUG;

ANAPHYLAXIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; BASOPHIL; BODY TEMPERATURE; CONTROLLED STUDY; DESENSITIZATION; DRUG DOSE INCREASE; DRUG EFFICACY; ENZYME RELEASE; FEMALE; GEL FILTRATION CHROMATOGRAPHY; HISTAMINE RELEASE; HUMAN; HUMAN CELL; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOTHERAPY; IN VIVO STUDY; MALE; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PEANUT ALLERGY; PRIORITY JOURNAL; PROVOCATION TEST; TREATMENT RESPONSE;

2S ALBUMINS, PLANT; ANAPHYLAXIS; ANIMALS; ANTIGENS, PLANT; ARACHIS HYPOGAEA; BASOPHILS; DESENSITIZATION, IMMUNOLOGIC; DISEASE MODELS, ANIMAL; FEMALE; GLYCOPROTEINS; HISTAMINE; HUMANS; MALE; MICE; PEANUT HYPERSENSITIVITY; TRYPTASES;

EID: 84863010974     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2011.03934.x     Document Type: Article

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