Novel mechanism for FcεRI-mediated signal transducer and activator of transcription 5 (STAT5) tyrosine phosphorylation and the selective influence of STAT5B over mast cell cytokine production

Journal of Biological Chemistry

Volumn 287, Issue 3, 2012, Pages 2045-2054

  Pullen, Nicholas A ^a   Barnstein, Brian O ^a   Falanga, Yves T ^a   Wang, Zhengqi ^b   Suzuki, Ryo ^c   Tamang, Tenchee D Lama ^a   Khurana, Michele C ^a   Harry, Emily A ^a   Draber, Petr ^d   Bunting, Kevin D ^b   Mizuno, Kazuya ^e   Wilson, Bridget S ^f   Ryan, John J ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^d INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^e TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^f UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRUTON'S TYROSINE KINASE; CHOLESTEROL DEPLETION; CYTOKINE PRODUCTION; HIGH AFFINITY; IMMUNOPRECIPITATIONS; ISOFORMS; KNOCK OUTS; MAST CELLS; NEGATIVE REGULATORS; PHARMACOLOGICAL INHIBITORS; SCAFFOLDING PROTEINS; SIGNAL TRANSDUCERS; TYROSINE PHOSPHATASE; TYROSINE PHOSPHORYLATION;

AMINO ACIDS; CELLS; CHEMICAL ACTIVATION; ENZYMES;

PHOSPHORYLATION;

BRUTON TYROSINE KINASE; FC RECEPTOR; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; JANUS KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN GAB2; PROTEIN KINASE B; PROTEIN KINASE FYN; PROTEIN KINASE LYN; PROTEIN KINASE SYK; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; SCAFFOLD PROTEIN; SMALL INTERFERING RNA; STAT5 PROTEIN; STAT5B PROTEIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL FUNCTION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME DEFICIENCY; IMMUNOBLOTTING; LIPID RAFT; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; CELLS, CULTURED; CHOLESTEROL; CYTOKINES; JANUS KINASE 2; MAST CELLS; MICE; MICE, KNOCKOUT; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-FYN; RECEPTORS, IGE; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STAT5 TRANSCRIPTION FACTOR;

MURINAE;

EID: 84862973257     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.311142     Document Type: Article

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