Automated high-throughput liquid-liquid extraction for initial purification of combinatorial libraries

Analytical Chemistry

Volumn 72, Issue 2, 2000, Pages 261-266

  Peng, Sean X ^a   Henson, Charles ^a   Strojnowski, Michael J ^a   Golebiowski, Adam ^a   Klopfenstein, Sean R ^a  

^a PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE;

ARTICLE; AUTOMATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION PROCEDURE; LIQUID LIQUID EXTRACTION; PARTITION COEFFICIENT; PURIFICATION;

AMINES; CHEMISTRY, ORGANIC; ROBOTICS; SOLVENTS;

EID: 0034650464     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac990946v     Document Type: Article

References (9)

1. Dolle, R. E.; Nelson, K. H. J. Comb. Chem. 1999, 1, 235-282.
2. Czarnik, A. W. Anal. Chem. 1998, 70, 378A-386A.
3. Zeng, L.; Kassel, D. B. Anal. Chem. 1998, 70, 4380-4388.
4. Janiszewski, J.; Schneider, R. P.; Hoffmaster, K.; Swyden, M.; Wells, D.; Fouda, H. Rapid Commun. Mass. Spectrom. 1997, 11, 1033-1037.
5. Rossi, D. T. LC-GC 1999, 17, S4-S8.
6. Cheng, S.; Comer, D. D.; Williams, J. P.; Myers, P. L.; Boger, D. L. J. Am. Chem. Soc. 1996, 118, 2567-2573.
7. Johnson, C. R.; Zhang, B.; Fantauzzi, P.; Hocker, M.; Yager, K. M. Tetrahedron 1998, 54, 4097-4106.
8. Kaldor, S. W.; Siegel, M. G.; Fritz, J. E.; Dressman, B. A.; Hahn, P. J. Tetrahedron Lett. 1996, 37, 7193-7196.
9. Booth, R. J.; Hodges, J. C. J. Am. Chem. Soc. 1997, 119, 4882-4886.