메뉴 건너뛰기




Volumn 1, Issue 4, 2010, Pages 281-295

DETANONOate is a potent chemo\radio-sensitizing agent in colon and colorectal cancers as assessed in in vitro and in vivo established tumor xenografts

Author keywords

AIF; BAX; Ionizing radiation; Pathological complete response; Rectal cancer

Indexed keywords

3,3 BIS(2 AMINOETHYL) 1 HYDROXY 2 OXOTRIAZENE; APOPTOSIS INDUCING FACTOR; CISPLATIN; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P27;

EID: 84862951120     PISSN: 21518017     EISSN: 21518025     Source Type: Journal    
DOI: 10.1615/ForumImmunDisTher.v1.i4.30     Document Type: Article
Times cited : (3)

References (52)
  • 2
    • 44249093758 scopus 로고    scopus 로고
    • Recent advances in the molecular diagnosis and prognosis of colorectal cancer
    • Huerta S. Recent advances in the molecular diagnosis and prognosis of colorectal cancer. Expert Rev Mol Diagn. 2008;8:277-88.
    • (2008) Expert Rev Mol Diagn. , vol.8 , pp. 277-288
    • Huerta, S.1
  • 4
    • 6944230093 scopus 로고    scopus 로고
    • Colon cancer survival rates with the new American joint committee on cancer sixth edition staging
    • O'Connell JB, Maggard MA, Ko CY. Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging. J Natl Cancer Inst. 2004;96:1420-5.
    • (2004) J Natl Cancer Inst. , vol.96 , pp. 1420-1425
    • O'Connell, J.B.1    Maggard, M.A.2    Ko, C.Y.3
  • 5
    • 68049110611 scopus 로고    scopus 로고
    • Small bowel obstruction due to metastatic colon cancer
    • Huerta S, Li C. Small bowel obstruction due to metastatic colon cancer. Anti-Cancer Drugs. 2009;20:S15-8.
    • (2009) Anti-Cancer Drugs , vol.20 , pp. S15-S18
    • Huerta, S.1    Li, C.2
  • 6
    • 68049086899 scopus 로고    scopus 로고
    • Bowel perforation from bevacizumab for the management of colorectal cancer
    • Huerta S, Li HC. Bowel perforation from bevacizumab for the management of colorectal cancer. Anti-Cancer Drugs. 2009;20:S19-21.
    • (2009) Anti-Cancer Drugs , vol.20 , pp. S19-S21
    • Huerta, S.1    Li, H.C.2
  • 7
    • 68049093187 scopus 로고    scopus 로고
    • Bevacizumab-associated hypertension: Etiology, incidence, and management
    • Huerta S, Li HC. Bevacizumab-associated hypertension: etiology, incidence, and management. Anti-Cancer Drugs. 2009;20;S22-4.
    • (2009) Anti-Cancer Drugs , vol.20 , pp. S22-S24
    • Huerta, S.1    Li, H.C.2
  • 10
    • 58149182297 scopus 로고    scopus 로고
    • Nitric oxide donors: Novel cancer therapeutics (review)
    • Huerta S, Chilka S, Bonavida B. Nitric oxide donors: novel cancer therapeutics (review). Int J Oncol. 2008;33:909-27.
    • (2008) Int J Oncol. , vol.33 , pp. 909-927
    • Huerta, S.1    Chilka, S.2    Bonavida, B.3
  • 11
    • 61849182029 scopus 로고    scopus 로고
    • In vitro and in vivo sensitization of SW620 metastatic colon cancer cells to CDDP-induced apoptosis by the nitric oxide donor DETANONOate: Involvement of AIF
    • Huerta S, Baay-Guzman G, Gonzalez-Bonilla CR, Livingston EH, Huerta-Yepez S, Bonavida B. In vitro and in vivo sensitization of SW620 metastatic colon cancer cells to CDDP-induced apoptosis by the nitric oxide donor DETANONOate: Involvement of AIF. Nitric Oxide. 2009;20:182-94.
    • (2009) Nitric Oxide , vol.20 , pp. 182-194
    • Huerta, S.1    Baay-Guzman, G.2    Gonzalez-Bonilla, C.R.3    Livingston, E.H.4    Huerta-Yepez, S.5    Bonavida, B.6
  • 12
    • 67749086634 scopus 로고    scopus 로고
    • Radio-sensitization of HT-29 cells and xenografts by the nitric oxide donor DETANONOate
    • Gao X, Saha D, Kapur P, Anthony T, Livingston EH, Huerta S. Radio-sensitization of HT-29 cells and xenografts by the nitric oxide donor DETANONOate. J Surg Oncol. 2009;100:149-58.
    • (2009) J Surg Oncol. , vol.100 , pp. 149-158
    • Gao, X.1    Saha, D.2    Kapur, P.3    Anthony, T.4    Livingston, E.H.5    Huerta, S.6
  • 14
    • 0035853035 scopus 로고    scopus 로고
    • Nitric oxide-induced cytostasis and cell cycle arrest of a human breast cancer cell line (MDA-MB-231): Potential role of cyclin dl
    • Pervin S, Singh R, Chaudhuri G. Nitric oxide-induced cytostasis and cell cycle arrest of a human breast cancer cell line (MDA-MB-231): potential role of cyclin Dl. Proc Natl Acad Sci USA. 2001;98:3583-8.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3583-3588
    • Pervin, S.1    Singh, R.2    Chaudhuri, G.3
  • 15
    • 33645235263 scopus 로고    scopus 로고
    • Nitric oxide attenuates resistance to doxorubicin in three-dimensional aggregates of human breast carcinoma cells
    • Muir CP, Adams MA, Graham CH. Nitric oxide attenuates resistance to doxorubicin in three-dimensional aggregates of human breast carcinoma cells. Breast Cancer Res Treat. 2006;96:169-76.
    • (2006) Breast Cancer Res Treat. , vol.96 , pp. 169-176
    • Muir, C.P.1    Adams, M.A.2    Graham, C.H.3
  • 16
    • 0035874941 scopus 로고    scopus 로고
    • Potentiation of nitric oxide-induced apoptosis of MDA-MB-468 cells by farnesyltransferase inhibitor: Implications in breast cancer
    • Pervin S, Singh R, Gau CL, Edamatsu H, Tamanoi F, Chaudhuri G. Potentiation of nitric oxide-induced apoptosis of MDA-MB-468 cells by farnesyltransferase inhibitor: implications in breast cancer. Cancer Res. 2001;61:4701-6.
    • (2001) Cancer Res. , vol.61 , pp. 4701-4706
    • Pervin, S.1    Singh, R.2    Gau, C.L.3    Edamatsu, H.4    Tamanoi, F.5    Chaudhuri, G.6
  • 22
    • 61849093931 scopus 로고    scopus 로고
    • Decreased levels of AIF renders resistance to oxaliplatin mediated apoptosis in the progression of colon cancer carcinogenesis beyond caspase-3 activity
    • Huerta S, Anguiano-Hernandez YM, Goulet EJ, Huerta-Yepez S, Livingston EH. Decreased levels of AIF renders resistance to oxaliplatin mediated apoptosis in the progression of colon cancer carcinogenesis beyond caspase-3 activity. Am J Gastroenterol. 2006;10:S196.
    • (2006) Am J Gastroenterol. , vol.10 , pp. S196
    • Huerta, S.1    Anguiano-Hernandez, Y.M.2    Goulet, E.J.3    Huerta-Yepez, S.4    Livingston, E.H.5
  • 23
    • 34548036056 scopus 로고    scopus 로고
    • Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: Roles of fas, apaf-1, NFkappaB, IAPs, smac/DIABLO, and AIF
    • Huerta S, Heinzerling JH, nguiano-Hernandez YM, Huerta-Yepez S, Lin J, Chen D, Bonavida B, Livingston EH. Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF. J Surg Res. 2007;142:184-94.
    • (2007) J Surg Res. , vol.142 , pp. 184-194
    • Huerta, S.1    Heinzerling, J.H.2    Nguiano-Hernandez, Y.M.3    Huerta-Yepez, S.4    Lin, J.5    Chen, D.6    Bonavida, B.7    Livingston, E.H.8
  • 24
    • 0034617449 scopus 로고    scopus 로고
    • Apoptosis-inducing factor (AIF): A ubiquitous mitochondrial oxidoreductase involved in apoptosis
    • Daugas E, Nochy D, Ravagnan L, Loeffler M, Susin SA, Zamzami N, Kroemer G. Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis. FEBS Lett. 2000;476:118-23.
    • (2000) FEBS Lett. , vol.476 , pp. 118-123
    • Daugas, E.1    Nochy, D.2    Ravagnan, L.3    Loeffler, M.4    Susin, S.A.5    Zamzami, N.6    Kroemer, G.7
  • 25
    • 23144445839 scopus 로고    scopus 로고
    • Sulindac activates nuclear translocation of AIF, DFF40 and endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells
    • Park YC, Jeong JH, Park KJ, Choi HJ, Park YM, Jeong BK, Higuchi Y, Yoo YH. Sulindac activates nuclear translocation of AIF, DFF40 and endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells. Life Sci. 2005;77:2059-70.
    • (2005) Life Sci. , vol.77 , pp. 2059-2070
    • Park, Y.C.1    Jeong, J.H.2    Park, K.J.3    Choi, H.J.4    Park, Y.M.5    Jeong, B.K.6    Higuchi, Y.7    Yoo, Y.H.8
  • 26
    • 31844435395 scopus 로고    scopus 로고
    • Tetracycline analogues (doxycycline and COL-3) induce caspase-dependent and -independent apoptosis in human colon cancer cells
    • Onoda T, Ono T, Dhar DK, Yamanoi A, Nagasue N. Tetracycline analogues (doxycycline and COL-3) induce caspase-dependent and -independent apoptosis in human colon cancer cells. Int J Cancer. 2006;118:1309-15.
    • (2006) Int J Cancer , vol.118 , pp. 1309-1315
    • Onoda, T.1    Ono, T.2    Dhar, D.K.3    Yamanoi, A.4    Nagasue, N.5
  • 27
    • 33947724731 scopus 로고    scopus 로고
    • Induction of apoptosis and cell-cycle arrest in human colon cancer cells by meclizine
    • Lin JC, Ho YS, Lee JJ, Liu CL, Yang TL, Wu CH. Induction of apoptosis and cell-cycle arrest in human colon cancer cells by meclizine. Food Chem Toxicol. 2007;45:935-44.
    • (2007) Food Chem Toxicol. , vol.45 , pp. 935-944
    • Lin, J.C.1    Ho, Y.S.2    Lee, J.J.3    Liu, C.L.4    Yang, T.L.5    Wu, C.H.6
  • 28
    • 21244502193 scopus 로고    scopus 로고
    • Flavone initiates a hierarchical activation of the caspase-cas-cade in colon cancer cells
    • Erhart LM, Lankat-Buttgereit B, Schmidt H, Wenzel U, Daniel H, Goke R. Flavone initiates a hierarchical activation of the caspase-cas-cade in colon cancer cells. Apoptosis. 2005;10:611-7.
    • (2005) Apoptosis , vol.10 , pp. 611-617
    • Erhart, L.M.1    Lankat-Buttgereit, B.2    Schmidt, H.3    Wenzel, U.4    Daniel, H.5    Goke, R.6
  • 29
    • 17844392101 scopus 로고    scopus 로고
    • Human colon cancer cells lacking bax resist curcumin-induced apoptosis and bax requirement is dispensable with ectopic expression of smac or downregulation of bcl-XL
    • Rashmi R, Kumar S, Karunagaran D. Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL. Carcinogenesis. 2005;26:713-23.
    • (2005) Carcinogenesis , vol.26 , pp. 713-723
    • Rashmi, R.1    Kumar, S.2    Karunagaran, D.3
  • 30
    • 0037444163 scopus 로고    scopus 로고
    • Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin
    • Diaz GD, Li Q, Dashwood RH. Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin. Cancer Res. 2003;63:1254-61.
    • (2003) Cancer Res. , vol.63 , pp. 1254-1261
    • Diaz, G.D.1    Li, Q.2    Dashwood, R.H.3
  • 31
    • 21844434671 scopus 로고    scopus 로고
    • Molecular mechanisms of econazole-induced toxicity on human colon cancer cells: G0/G1 cell cycle arrest and caspase 8-independent apoptotic signaling pathways
    • Ho YS, Wu CH, Chou HM, Wang YJ, Tseng H, Chen CH, Chen LC, Lee CH, Lin SY. Molecular mechanisms of econazole-induced toxicity on human colon cancer cells: G0/G1 cell cycle arrest and caspase 8-independent apoptotic signaling pathways. Food Chem Toxicol. 2005;43:1483-95.
    • (2005) Food Chem Toxicol. , vol.43 , pp. 1483-1495
    • Ho, Y.S.1    Wu, C.H.2    Chou, H.M.3    Wang, Y.J.4    Tseng, H.5    Chen, C.H.6    Chen, L.C.7    Lee, C.H.8    Lin, S.Y.9
  • 32
    • 57149120502 scopus 로고    scopus 로고
    • Apoptosis-inducing factor and colon cancer
    • Millan A, Huerta S. Apoptosis-inducing factor and colon cancer. J Surg Res. 2009;151:163-70.
    • (2009) J Surg Res. , vol.151 , pp. 163-170
    • Millan, A.1    Huerta, S.2
  • 35
    • 0029812216 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptosis: P53-dependent and p53-independent signalling pathways
    • Messmer UK, Brune B. Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways. Biochem J. 1996;319: 299-305.
    • (1996) Biochem J. , vol.319 , pp. 299-305
    • Messmer, U.K.1    Brune, B.2
  • 36
    • 0033538443 scopus 로고    scopus 로고
    • Activation of the cell death program by nitric oxide involves inhibition of the proteasome
    • Glockzin S, von KA, Scheffner M, Brune B. Activation of the cell death program by nitric oxide involves inhibition of the proteasome. J Biol Chem. 1999;274:19581-6.
    • (1999) J Biol Chem. , vol.274 , pp. 19581-19586
    • Glockzin, S.1    Von, K.A.2    Scheffner, M.3    Brune, B.4
  • 37
    • 2342583373 scopus 로고    scopus 로고
    • Apoptotic signaling pathways induced by nitric oxide in human lymphoblastoid cells expressing wild-type or mutant p53
    • Li CQ, Robles AI, Hanigan CL, Hofseth LJ, Trudel LJ, Harris CC, Wogan GN. Apoptotic signaling pathways induced by nitric oxide in human lymphoblastoid cells expressing wild-type or mutant p53. Cancer Res. 2004;64:3022-9.
    • (2004) Cancer Res. , vol.64 , pp. 3022-3029
    • Li, C.Q.1    Robles, A.I.2    Hanigan, C.L.3    Hofseth, L.J.4    Trudel, L.J.5    Harris, C.C.6    Wogan, G.N.7
  • 38
    • 0036244305 scopus 로고    scopus 로고
    • Nitric oxide and cell signaling pathways in mito-chondrial-dependent apoptosis
    • Boyd CS, Cadenas E. Nitric oxide and cell signaling pathways in mito-chondrial-dependent apoptosis. Biol Chem. 2002;383:411-23.
    • (2002) Biol Chem. , vol.383 , pp. 411-423
    • Boyd, C.S.1    Cadenas, E.2
  • 41
    • 0035296203 scopus 로고    scopus 로고
    • Role of nitric oxide in carcinogenesis and tumour progression
    • Lala PK, Chakraborty C. Role of nitric oxide in carcinogenesis and tumour progression. Lancet Oncol. 2001;2:149-56.
    • (2001) Lancet Oncol. , vol.2 , pp. 149-156
    • Lala, P.K.1    Chakraborty, C.2
  • 43
    • 0032973685 scopus 로고    scopus 로고
    • Nitric oxide inhibits proliferation of human endothelial cells via a mechanism independent of cGMP
    • Heller R, Polack T, Grabner R, Till U. Nitric oxide inhibits proliferation of human endothelial cells via a mechanism independent of cGMP. Atherosclerosis. 1999;144:49-57.
    • (1999) Atherosclerosis. , vol.144 , pp. 49-57
    • Heller, R.1    Polack, T.2    Grabner, R.3    Till, U.4
  • 45
    • 0038731372 scopus 로고    scopus 로고
    • Nitric oxide induces cyclooxygenase expression and inhibits cell growth in colon cancer cell lines
    • Liu Q, Chan ST, Mahendran R. Nitric oxide induces cyclooxygenase expression and inhibits cell growth in colon cancer cell lines. Carcinogenesis. 2003;24:637-42.
    • (2003) Carcinogenesis , vol.24 , pp. 637-642
    • Liu, Q.1    Chan, S.T.2    Mahendran, R.3
  • 48
    • 0028362325 scopus 로고
    • Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation
    • Shibata D, Peinado MA, Ionov Y, Malkhosyan S, Perucho M. Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation. Nat Genet. 1994;6:273-81.
    • (1994) Nat Genet. , vol.6 , pp. 273-281
    • Shibata, D.1    Peinado, M.A.2    Ionov, Y.3    Malkhosyan, S.4    Perucho, M.5
  • 49
    • 0037156948 scopus 로고    scopus 로고
    • Nitric oxide of human colorectal adenocarcinoma cell lines promotes tumour cell invasion
    • Siegert A, Rosenberg C, Schmitt WD, Denkert C, Hauptmann S. Nitric oxide of human colorectal adenocarcinoma cell lines promotes tumour cell invasion. Br J Cancer. 2002;86:1310-5.
    • (2002) Br J Cancer , vol.86 , pp. 1310-1315
    • Siegert, A.1    Rosenberg, C.2    Schmitt, W.D.3    Denkert, C.4    Hauptmann, S.5
  • 50
    • 67650441783 scopus 로고    scopus 로고
    • Mechanisms of resistance to ionizing radiation in rectal cancer
    • Huerta S, Gao X, Saha D. Mechanisms of resistance to ionizing radiation in rectal cancer. Expert Rev Mol Diagn. 2009;9:469-80.
    • (2009) Expert Rev Mol Diagn. , vol.9 , pp. 469-480
    • Huerta, S.1    Gao, X.2    Saha, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.