Nitric oxide induces cyclooxygenase expression and inhibits cell growth in colon cancer cell lines

Carcinogenesis

Volumn 24, Issue 4, 2003, Pages 637-642

  Liu, Qiang ^a,b   Chan, S T F ^c   Mahendran, Ratha ^a  

^a NATIONAL UNIVERSITY HOSPITAL   (Singapore)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NITRIC OXIDE; NITRIC OXIDE DONOR; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; S NITROSOGLUTATHIONE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CANCER TISSUE; CELL CYCLE; CELLULAR DISTRIBUTION; COLON ADENOCARCINOMA; COLON CARCINOGENESIS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN EXPRESSION; UPREGULATION;

ADENOCARCINOMA; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; BLOTTING, WESTERN; CELL DIVISION; COLONIC NEOPLASMS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DINOPROSTONE; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; NITRIC OXIDE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; S-NITROSOGLUTATHIONE; TUMOR CELLS, CULTURED;

EID: 0038731372     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgg014     Document Type: Article

References (35)

1. Abramson,S.B., Amin,A.R., Clancy,R.M. and Attur,M. (2001) The role of nitric oxide in tissue destruction. Best Pract. Res. Clin. Rheumatol., 15, 831-845.
2. Wink, D.A., Vodovotz, Y., Laval, J., Laval, F., Dewhirst, M.W. and Mitchell, J.B. (1998) The multifaceted roles of nitric oxide in cancer. Carcinogenesis, 19, 711-721.
3. Kim, P.K., Zamora, R., Petrosko, P. and Billiar, T.R. (2001) The regulatory role of nitric oxide in apoptosis. Int. Immunopharmacol., 1, 1421-1441.
4. Yagihashi, N., Kasajima, H., Sugai, S., Matsumoto, K., Ebina, Y., Morita, T., Murakami, T. and Yagahashi, S. (2000) Increased in situ expression of nitric oxide synthase in human colorectal cancer. Virch. Arch., 436, 109-114.
5. Kojima, M., Morisaki, T., Tsukahara, Y., Uchiyama, A., Matsunari, Y., Mibu, R. and Tanaka, M. (1999) Nitric oxide synthase expression and nitric oxide production in human colon carcinoma tissue. J. Surg. Oncol., 70, 222-229.
6. Ambs, S., Merriam, W.G., Bennett, W.P., Felley-Bosco, E., Ogunfusika, M.O., Oser, S.M., Klein, S., Shields, P.G., Billiar, T.R. and Harris, C.C. (1998) Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. Cancer Res., 58, 334-341.
7. Hao, X.P., Pretlow, T.G., Rao, J.S. and Pretlow, T.P. (2001) Inducible nitric oxide synthase is expressed similarly in multiple aberrant crypt foci and colorectal tumors from the same patients. Cancer Res., 61, 419-422.
8. Chhatwal, V.J., Ngoi, S.S., Chan, S.T., Chia, Y.W. and Moochhala, S.M. (1994) Aberrant expression of nitric oxide synthase in human polyps, neoplastic colonic mucosa and surrounding peritumoral normal mucosa. Cancinogenesis, 15, 2081-2085.
9. Bing, R.J., Miyataka, M., Rich, K.A., Hanson, N., Wang, X., Slosser, H.D. and Shi, S.R. (2001) Nitric oxide, prostanoids, cyclooxygenase and angiogenesis in colon and breast cancer. Clin. Cancer Res., 7, 3385-3392
10. Roberts, P.J., Riley, G.P., Morgan, K., Miller, R., Hunter, J.O. and Middleton, S.J. (2001) The physiological expression of inducible nitric oxide synthase in the human colon. J. Clin. Pathol., 54, 293-297.
11. Onier, N., Hilpert, S., Reveneau, S., Arnould, L., Saint-Giorgio, V., Exbrayat, J.M. and Jeannin, J.F. (1999) Expression of inducible nitric oxide synthase in tumors in relation with their regression induced by lipid S in rats. Int. J. Cancer, 81, 755-760.
12. Xie, K., Huang, S., Dong, Z., Gutman, M. and Fidler, I.J. (1995) Direct correlation between expression of endogenous inducible nitric oxide synthase and regression of M5076 reticulum cell sarcoma hepatic metastases in mice treated with liposomes containing lipopeptide CGP 31362. Cancer Res., 55, 3123-3131.
13. Rao, C.V., Indranie, C., Simi, B., Manning, P.T., Connor, J.R. and Reddy, B.S. (2002) Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor. Cancer Res., 62, 165-170.
14. Kawamori, T., Takahashi, M., Watanabe, K., Ohta, T., Nakatsuki, S., Sugimura, T. and Wakabayashi, K. (2000) Suppression of azoxymethane-induced colonic aberrant crypt foci by a nitric oxide synthase inhibitor. Cancer Lett., 148, 33-37.
15. Rao, C.V., Kawamori, T., Hamid, R. and Reddy, B.S. (1999) Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor. Carcinogenesis, 20, 641-644.
16. Siegert, A., Rosenberg, C., Schmitt, W.D., Denkert, C. and Hauptmann, S. (2002) Nitric oxide of human colorectal adenocarcinoma cell lines promotes tumor cell invasion. Br. J. Cancer, 86, 1310-1315.
17. Jenkins, D.C., Charles, I.G., Thomsen, L.L., Moss, D.W., Holmes, L.S., Baylis, S.A., Rhodes, P., Westmore, K., Emson, P.C. and Moncada, S. (1995) Roles of nitric oxide in tumor growth. Proc. Natl Acad. Sci. USA, 92, 4392-4396.
18. Xu, W., Liu, L. and Charles, I.G. (2002) Microencapsulated iNOS-expressing cells cause tumor suppression in mice. FASEB J., 16, 213-215.
19. Scott, D.J., Hull, M.A., Cartwright, E.J., Lam, W.K., Tisbury, A., Poulsom, R., Markham, A.F., Bonifer, C. and Coletta, P.L. (2001) Lack of inducible nitric oxide synthase promotes intestinal tumorigenesis in the Apc (Min/+) mouse. Gastroenterology, 121, 889-899.
20. Ahn, B. and Ohshima, H. (2001) Suppression of intestinal polyposis in Apc (Min/+) mice by inhibiting nitric oxide production. Cancer Res., 61, 8357-8360.
21. Chan, T.A. (2002) Nonsteroidal anti-inflammatory drugs, apoptosis and colon-cancer chemoprevention. Lancet Oncol., 3, 166-174.
22. Thun, M.J., Henley, S.J. and Patrono, C. (2002) Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic and clinical issues. J. Natl Cancer Inst., 94, 252-266.
23. Perez-Sala, D. and Lamas, S. (2001) Regulation of cyclooxygenase-2 expression by nitric oxide in cells. Antioxid. Redox Signal., 3, 231-248.
24. Weinberg, J.B. (2000) Nitric oxide synthase 2 and cyclooxygenase 2 interactions in inflammation. Immunol. Res., 22, 319-341.
25. Smith, J.N. and Dasgupta, T.P. (2000) Kinetics and mechanism of the decomposition of S-nitrosoglutathione by L-ascorbic acid and copper ions in aqueous solution to produce nitric oxide. Nitric Oxide, 4, 57-66.
26. Smith, M.L., Hawcroft, G. and Hull, M.A. (2000) The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action. Eur. J. Cancer, 36, 664-674.
27. Feelisch, M. and Stamler, J.S. (1996) Methods in Nitric Oxide Research. John Wiley & Sons Ltd, Chicester, pp. 492-497.
28. Buga, G.M., Wei, L.H., Bauer, P.M., Fukuto, J.M. and Ignarro, L.J. (1998) NG-hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms. Am. J. Physiol., 275 (4 Pt 2): R1256-R1264.
29. Zeng, H., Spencer, N.Y. and Hogg, N. (2001) Metabolism of S-nitrosoglutathione by endothelial cells. Am. J. Physiol. Heart Circ. Physiol., 281, H432-H439.
30. Clancy, R., Varenika, B., Huang, W., Ballou, L., Attur, M., Amin, A.R. and Abramson, S.B. (2000) Nitric oxide synthase/COX cross-talk: nitric oxide activates COX-1 but inhibits COX-2-derived prostaglandin production. J. Immunol., 165, 1582-1587.
31. Mei, J.M., Hord, N.G., Winterstein, D.F., Donald, S.P. and Phang, J.M. (2000) Expression of prostaglandin endoperoxide H synthase-2 induced by nitric oxide in conditionally immortalized murine colonic epithelial cells. FASEB J., 14, 1188-1201.
32. Pai, R., Soreghan, B., Szabo, I.L., Pavelka, M., Baatar, D. and Tarnawski, A.S. (2002) Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy. Nature Med., 8, 289-293.
33. Williams, J.L., Borgo, S., Hasan, I., Castillo, E., Traganos, F. and Rigas, B. (2001) Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs: implications for colon cancer chemoprevention. Cancer Res., 61, 3285-3289.
34. Lavagna, C., Burgaud, J.L., Del Soldato, P. and Rampal, P. (2001) Anti-proliferative effects of nitrosulindac on human colon adenocarcinoma cell lines. Biochem. Biophys. Res. Commun., 284, 808-816.
35. Bak, A.W., McKnight, W., Li ,P., Del Soldato, P., Calignano, A., Cirino, G. and Wallace, J.L. (1998) Cyclooxygenase-independent chemoprevention with an aspirin derivative in a rat model of colonic adenocarcinoma. Life Sci., 61, PL 367-373.