-
3
-
-
33644838137
-
Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity
-
DOI 10.1161/01.RES.0000199348.10580.1d, PII 0000301220060106000018
-
Barouch LA, Gao D, Chen L, Miller KL, Xu W, Phan AC, Kittleson MM, Minhas KM, Berkowitz DE, Wei C, Hare JM. 2006. Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity. Circ Res 98:119-124. (Pubitemid 43970211)
-
(2006)
Circulation Research
, vol.98
, Issue.1
, pp. 119-124
-
-
Barouch, L.A.1
Gao, D.2
Chen, L.3
Miller, K.L.4
Xu, W.5
Phan, A.C.6
Kittleson, M.M.7
Minhas, K.M.8
Berkowitz, D.E.9
Wei, C.10
Hare, J.M.11
-
4
-
-
0037464448
-
Mitochondria in apoptosis of ischemic heart
-
Borutaite V, Brown GC. 2003. Mitochondria in apoptosis of ischemic heart. FEBS Lett 541:1-5.
-
(2003)
FEBS Lett
, vol.541
, pp. 1-5
-
-
Borutaite, V.1
Brown, G.C.2
-
5
-
-
34948813565
-
Leptin decreases apoptosis and alters BCL-2: Bax ratio in clonal rodent pancreatic beta-cells
-
Brown JE, Dunmore SJ. 2007. Leptin decreases apoptosis and alters BCL-2: Bax ratio in clonal rodent pancreatic beta-cells. Diabetes Metab Res Rev 23:497-502.
-
(2007)
Diabetes Metab Res Rev
, vol.23
, pp. 497-502
-
-
Brown, J.E.1
Dunmore, S.J.2
-
6
-
-
20444403798
-
Apoptotic pathways are inhibited by leptin receptor activation in neutrophils
-
Bruno A, Conus S, Schmid I, Simon HU. 2005. Apoptotic pathways are inhibited by leptin receptor activation in neutrophils. J Immunol 174:8090-8096. (Pubitemid 40806320)
-
(2005)
Journal of Immunology
, vol.174
, Issue.12
, pp. 8090-8096
-
-
Bruno, A.1
Conus, S.2
Schmid, I.3
Simon, H.-U.4
-
7
-
-
33645556312
-
Bax translocates to mitochondria of heart cells during simulated ischaemia: Involvement of AMP-activated and p38 mitogen-activated protein kinases
-
Capano M, Crompton M. 2006. Bax translocates to mitochondria of heart cells during simulated ischaemia: Involvement of AMP-activated and p38 mitogen-activated protein kinases. Biochem J 395:57-64.
-
(2006)
Biochem J
, vol.395
, pp. 57-64
-
-
Capano, M.1
Crompton, M.2
-
8
-
-
0029019024
-
Further characterisation of the in situ terminal deoxynucleotidyl transferase (TdT) assay for the flow cytometric analysis of apoptosis in drug resistant and drug sensitive leukaemic cells
-
Chapman RS, Chresta CM, Herberg AA, Beere HM, Heer S, Whetton AD, Hickman JA, Dive C. 1995. Further characterisation of the in situ terminal deoxynucleotidyl transferase (TdT) assay for the flow cytometric analysis of apoptosis in drug resistant and drug sensitive leukaemic cells. Cytometry 20:245-256.
-
(1995)
Cytometry
, vol.20
, pp. 245-256
-
-
Chapman, R.S.1
Chresta, C.M.2
Herberg, A.A.3
Beere, H.M.4
Heer, S.5
Whetton, A.D.6
Hickman, J.A.7
Dive, C.8
-
9
-
-
34547819751
-
Leptin induces proliferation and anti-apoptosis in human hepatocarcinoma cells by up-regulating cyclin D1 and down-regulating Bax via a Janus kinase 2-linked pathway
-
DOI 10.1677/ERC-06-0027
-
Chen C, Chang YC, Liu CL, Liu TP, Chang KJ, Guo IC. 2007. Leptin induces proliferation and anti-apoptosis in human hepatocarcinoma cells by up-regulating cyclin D1 and down-regulating Bax via a Janus kinase 2-linked pathway. Endocr Relat Cancer 14:513-529. (Pubitemid 47242649)
-
(2007)
Endocrine-Related Cancer
, vol.14
, Issue.2
, pp. 513-529
-
-
Chen, C.1
Chang, Y.-C.2
Liu, C.-L.3
Liu, T.-P.4
Chang, K.-J.5
Guo, I.-C.6
-
10
-
-
0033564419
-
Increased cardiomyocyte apoptosis and changes in proapoptotic and antiapoptotic genes bax and bcl-2 during left ventricular adaptations to chronic pressure overload in the rat
-
Condorelli G, Morisco C, Stassi G, Notte A, Farina F, Sgaramella G, de Rienzo A, Roncarati R, Trimarco B, Lembo G. 1999. Increased cardiomyocyte apoptosis and changes in proapoptotic and antiapoptotic genes bax and bcl-2 during left ventricular adaptations to chronic pressure overload in the rat. Circulation 99:3071-3078. (Pubitemid 29270439)
-
(1999)
Circulation
, vol.99
, Issue.23
, pp. 3071-3078
-
-
Condorelli, G.1
Morisco, C.2
Stassi, G.3
Notte, A.4
Farina, F.5
Sgaramella, G.6
De Rienzo, A.7
Roncarati, R.8
Trimarco, B.9
Lembo, G.10
-
12
-
-
0842281645
-
Cell Death: Critical Control Points
-
DOI 10.1016/S0092-8674(04)00046-7
-
Danial NN, Korsmeyer SJ. 2004. Cell death: Critical control points. Cell 116:205-219. (Pubitemid 38167313)
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
13
-
-
34548391046
-
Apoptosis as a therapeutic target in heart failure
-
Das M. 2007. Apoptosis as a therapeutic target in heart failure. Am J Physiol Heart Circ Physiol 293:H1322-1323.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
-
-
Das, M.1
-
14
-
-
0038338315
-
C-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade
-
DOI 10.1042/BJ20021565
-
Desbiens KM, Deschesnes RG, Labrie MM, Desfosses Y, Lambert H, Landry J, Bellmann K. 2003. c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade. Biochem J 372:631-641. (Pubitemid 36723910)
-
(2003)
Biochemical Journal
, vol.372
, Issue.2
, pp. 631-641
-
-
Desbiens, K.M.1
Deschesnes, R.G.2
Labrie, M.M.3
Desfosses, Y.4
Lambert, H.5
Landry, J.6
Bellman, K.7
-
15
-
-
34547828051
-
Fitness or fatness - The debate continues for the role of leptin in obesity-associated heart dysfunction
-
DOI 10.2174/157339907781368959
-
Dong F, Ren J. 2007. Fitness or fatness-The debate continues for the role of leptin in obesity-associated heart dysfunction. Curr Diabetes Rev 3:159-164. (Pubitemid 47244060)
-
(2007)
Current Diabetes Reviews
, vol.3
, Issue.3
, pp. 159-164
-
-
Dong, F.1
Ren, J.2
-
16
-
-
44349154651
-
Leptin protects H9c2 rat cardiomyocytes from H(2)O(2)-induced apoptosis
-
Eguchi M, Liu Y, Shin EJ, Sweeney G. 2008. Leptin protects H9c2 rat cardiomyocytes from H(2)O(2)-induced apoptosis. FEBS J 275:3136-3144.
-
(2008)
FEBS J
, vol.275
, pp. 3136-3144
-
-
Eguchi, M.1
Liu, Y.2
Shin, E.J.3
Sweeney, G.4
-
17
-
-
31344455641
-
Leptin protects the cardiac myocyte cultures from hypoxic damage
-
DOI 10.1016/j.lfs.2005.06.039, PII S0024320505008751
-
Erkasap N, Ikizler M, Shneyvays V, Zinman T, Mamedova LK, Uyar R, Shainberg A. 2006. Leptin protects the cardiac myocyte cultures from hypoxic damage. Life Sci 78:1098-1102. (Pubitemid 43143467)
-
(2006)
Life Sciences
, vol.78
, Issue.10
, pp. 1098-1102
-
-
Erkasap, N.1
Ikizler, M.2
Shneyvays, V.3
Zinman, T.4
Mamedova, L.K.5
Uyar, R.6
Shainberg, A.7
-
18
-
-
33846064669
-
Protective effects of the PARP-1 inhibitor PJ34 in hypoxic-reoxygenated cardiomyoblasts
-
DOI 10.1007/s00018-006-6345-7
-
Fiorillo C, Ponziani V, Giannini L, Cecchi C, Celli A, Nassi N, Lanzilao L, Caporale R, Nassi P. 2006. Protective effects of the PARP-1 inhibitor PJ34 in hypoxic-reoxygenated cardiomyoblasts. Cell Mol Life Sci 63:3061-3071. (Pubitemid 46072308)
-
(2006)
Cellular and Molecular Life Sciences
, vol.63
, Issue.24
, pp. 3061-3071
-
-
Fiorillo, C.1
Ponziani, V.2
Giannini, L.3
Cecchi, C.4
Celli, A.5
Nassi, N.6
Lanzilao, L.7
Caporale, R.8
Nassi, P.9
-
19
-
-
33747500684
-
Optical and pharmacological tools to investigate the role of mitochondria during oxidative stress and neurodegeneration
-
DOI 10.1016/j.pneurobio.2006.07.001, PII S0301008206000694
-
Foster KA, Galeffi F, Gerich FJ, Turner DA, Muller M. 2006. Optical and pharmacological tools to investigate the role of mitochondria during oxidative stress and neurodegeneration. Prog Neurobiol 79:136-171. (Pubitemid 44255860)
-
(2006)
Progress in Neurobiology
, vol.79
, Issue.3
, pp. 136-171
-
-
Foster, K.A.1
Galeffi, F.2
Gerich, F.J.3
Turner, D.A.4
Muller, M.5
-
20
-
-
0027205172
-
Induction of DNA strand breaks associated with apoptosis during treatment of leukemias
-
Gorczyca W, Bigman K, Mittelman A, Ahmed T, Gong J, Melamed MR, Darzynkiewicz Z. 1993. Induction of DNA strand breaks associated with apoptosis during treatment of leukemias. Leukemia 7:659-670. (Pubitemid 23186018)
-
(1993)
Leukemia
, vol.7
, Issue.5
, pp. 659-670
-
-
Gorczyca, W.1
Bigman, K.2
Mittelman, A.3
Ahmed, T.4
Gong, J.5
Melamed, M.R.6
Darzynkiewicz, Z.7
-
21
-
-
0036234187
-
Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic signaling
-
DOI 10.1002/jcb.10156
-
Gordeladze JO, Drevon CA, Syversen U, Reseland JE. 2002. Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic signaling. J Cell Biochem 85:825-836. (Pubitemid 34462792)
-
(2002)
Journal of Cellular Biochemistry
, vol.85
, Issue.4
, pp. 825-836
-
-
Gordeladze, J.O.1
Drevon, C.A.2
Syversen, U.3
Reseland, J.E.4
-
23
-
-
2442716574
-
Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation
-
Gustafsson AB, Tsai JG, Logue SE, Crow MT, Gottlieb RA. 2004. Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation. J Biol Chem 279:21233-21238.
-
(2004)
J Biol Chem
, vol.279
, pp. 21233-21238
-
-
Gustafsson, A.B.1
Tsai, J.G.2
Logue, S.E.3
Crow, M.T.4
Gottlieb, R.A.5
-
25
-
-
33748078113
-
Obesity-A risk factor or a RISK factor for myocardial infarction?
-
Heusch G. 2006. Obesity-A risk factor or a RISK factor for myocardial infarction? Br J Pharmacol 149:1-3.
-
(2006)
Br J Pharmacol
, vol.149
, pp. 1-3
-
-
Heusch, G.1
-
26
-
-
17344375146
-
Bax ablation protects against myocardial ischemiareperfusion injury in transgenic mice
-
Hochhauser E, Kivity S, Offen D, Maulik N, Otani H, Barhum Y, Pannet H, Shneyvays V, Shainberg A, Goldshtaub V, Tobar A, Vidne BA. 2003. Bax ablation protects against myocardial ischemia-reperfusion injury in transgenicmice. Am J Physiol Heart Circ Physiol 284:H2351-H2359. (Pubitemid 36622451)
-
(2003)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.284
, Issue.6
-
-
Hoehhauser, E.1
Kivity, S.2
Offen, D.3
Maulik, N.4
Otani, H.5
Barhum, Y.6
Pannet, H.7
Shneyvays, V.8
Shainberg, A.9
Goldshtaub, V.10
Tobar, A.11
Vidne, B.A.12
-
27
-
-
21644454595
-
Bax translocates from cytosol to mitochondria in cardiac cells during apoptosis: Development of a GFP-Bax-stable H9c2 cell line for apoptosis analysis
-
DOI 10.1152/ajpheart.00879.2004
-
Hou Q, Hsu YT. 2005. Bax translocates from cytosol to mitochondria in cardiac cells during apoptosis: Development of a GFP-Bax-stable H9c2 cell line for apoptosis analysis. Am J Physiol Heart Circ Physiol 289:H477-H487. (Pubitemid 40934135)
-
(2005)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.289
, Issue.1
-
-
Hou, Q.1
Hsu, Y.-T.2
-
28
-
-
0034810432
-
Chronic hypoxia induces apoptosis in cardiac myocytes: A possible role for Bcl-2-like proteins
-
DOI 10.1006/bbrc.2001.5406
-
Jung F, Weiland U, Johns RA, Ihling C, Dimmeler S. 2001. Chronic hypoxia induces apoptosis in cardiac myocytes: A possible role for Bcl-2-like proteins. Biochem Biophys Res Commun 286:419-425. (Pubitemid 32924931)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.286
, Issue.2
, pp. 419-425
-
-
Jung, F.1
Weiland, U.2
Johns, R.A.3
Ihling, C.4
Dimmeler, S.5
-
29
-
-
0029065342
-
Single-step procedure for labeling DNA strand breaks with fluorescein- Or BODIPY-conjugated deoxynucleotides: Detection of apoptosis and bromodeoxyuridine incorporation
-
Li X, Traganos F, Melamed MR, Darzynkiewicz Z. 1995. Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: Detection of apoptosis and bromodeoxyuridine incorporation. Cytometry 20:172-180.
-
(1995)
Cytometry
, vol.20
, pp. 172-180
-
-
Li, X.1
Traganos, F.2
Melamed, M.R.3
Darzynkiewicz, Z.4
-
31
-
-
33846265642
-
Ischemia/reperfusion in rat heart induces leptin and leptin receptor gene expression
-
DOI 10.1016/j.lfs.2006.10.027, PII S0024320506008253
-
Matsui H, Motooka M, Koike H, Inoue M, Iwasaki T, Suzuki T, Kurabayashi M, Yokoyama T. 2007. Ischemia/reperfusion in rat heart induces leptin and leptin receptor gene expression. Life Sci 80:672-680. (Pubitemid 46091791)
-
(2007)
Life Sciences
, vol.80
, Issue.7
, pp. 672-680
-
-
Matsui, H.1
Motooka, M.2
Koike, H.3
Inoue, M.4
Iwasaki, T.5
Suzuki, T.6
Kurabayashi, M.7
Yokoyama, T.8
-
33
-
-
49849103205
-
A neutralizing leptin receptor antibody mitigates hypertrophy and hemodynamic dysfunction in the postinfarcted rat heart
-
Purdham DM, Rajapurohitam V, Zeidan A, Huang C, Gross GJ, Karmazyn M. 2008. A neutralizing leptin receptor antibody mitigates hypertrophy and hemodynamic dysfunction in the postinfarcted rat heart. Am J Physiol Heart Circ Physiol 295:H441-H446.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Purdham, D.M.1
Rajapurohitam, V.2
Zeidan, A.3
Huang, C.4
Gross, G.J.5
Karmazyn, M.6
-
34
-
-
11144287220
-
Apoptosis of ventricular myocytes: A means to an end
-
Regula KM, Kirshenbaum LA. 2005. Apoptosis of ventricular myocytes: A means to an end. J Mol Cell Cardiol 38:3-13.
-
(2005)
J Mol Cell Cardiol
, vol.38
, pp. 3-13
-
-
Regula, K.M.1
Kirshenbaum, L.A.2
-
35
-
-
39749105397
-
Stem-cell therapy for cardiac disease
-
Segers VF, Lee RT. 2008. Stem-cell therapy for cardiac disease. Nature 451:937-942.
-
(2008)
Nature
, vol.451
, pp. 937-942
-
-
Segers, V.F.1
Lee, R.T.2
-
37
-
-
33748030752
-
Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects
-
Smith CC, Mocanu MM, Davidson SM, Wynne AM, Simpkin JC, Yellon DM. 2006. Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects. Br J Pharmacol 149:5-13.
-
(2006)
Br J Pharmacol
, vol.149
, pp. 5-13
-
-
Smith, C.C.1
Mocanu, M.M.2
Davidson, S.M.3
Wynne, A.M.4
Simpkin, J.C.5
Yellon, D.M.6
-
38
-
-
33847028349
-
The prolyl hydroxylase oxygen-sensing pathway is cytoprotective and allows maintenance of mitochondrial membrane potential during metabolic inhibition
-
DOI 10.1152/ajpcell.00100.2006
-
Sridharan V, Guichard J, Bailey RM, Kasiganesan H, Beeson C, Wright GL. 2007. The prolyl hydroxylase oxygen-sensing pathway is cytoprotective and allows maintenance of mitochondrial membrane potential during metabolic inhibition. Am J Physiol Cell Physiol 292:C719-C728. (Pubitemid 46263471)
-
(2007)
American Journal of Physiology - Cell Physiology
, vol.292
, Issue.2
-
-
Sridharan, V.1
Guichard, J.2
Bailey, R.M.3
Kasiganesan, H.4
Beeson, C.5
Wright, G.L.6
-
39
-
-
0036000280
-
Leptin signalling
-
Sweeney G. 2002. Leptin signalling. Cell Signal 14:655-663.
-
(2002)
Cell Signal
, vol.14
, pp. 655-663
-
-
Sweeney, G.1
-
40
-
-
34548402079
-
Programmed death as a therapeutic target to reduce myocardial infarction
-
DOI 10.1016/j.tips.2007.07.004, PII S0165614707001836
-
Webster KA. 2007. Programmed death as a therapeutic target to reduce myocardial infarction. Trends Pharmacol Sci 28:492-499. (Pubitemid 47368699)
-
(2007)
Trends in Pharmacological Sciences
, vol.28
, Issue.9
, pp. 492-499
-
-
Webster, K.A.1
-
41
-
-
36348980042
-
Leptin protects against 6-hydroxydopamine-induced dopaminergic cell death via mitogen-activated protein kinase signaling
-
DOI 10.1074/jbc.M705426200
-
Weng Z, Signore AP, Gao Y, Wang S, Zhang F, Hastings T, Yin XM, Chen J. 2007. Leptin protects against 6-hydroxydopamine-induced dopaminergic cell death via mitogen-activated protein kinase signaling. J Biol Chem 282:34479-34491. (Pubitemid 350159488)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.47
, pp. 34479-34491
-
-
Weng, Z.1
Signore, A.P.2
Gao, Y.3
Wang, S.4
Zhang, F.5
Hastings, T.6
Yin, X.-M.7
Chen, J.8
-
42
-
-
33746721535
-
Asymmetric distribution of phospholipids in biomembranes
-
Yamaji-Hasegawa A, Tsujimoto M. 2006. Asymmetric distribution of phospholipids in biomembranes. Biol Pharm Bull 29:1547-1553.
-
(2006)
Biol Pharm Bull
, vol.29
, pp. 1547-1553
-
-
Yamaji-Hasegawa, A.1
Tsujimoto, M.2
-
43
-
-
33748130863
-
Essential role of Rho/ROCK-dependent processes and actin dynamics in mediating leptin-induced hypertrophy in rat neonatal ventricular myocytes
-
DOI 10.1016/j.cardiores.2006.06.024, PII S0008636306002938
-
Zeidan A, Javadov S, Karmazyn M. 2006. Essential role of Rho/ROCK-dependent processes and actin dynamics in mediating leptin-induced hypertrophy in rat neonatal ventricular myocytes. Cardiovasc Res 72:101-111. (Pubitemid 44310635)
-
(2006)
Cardiovascular Research
, vol.72
, Issue.1
, pp. 101-111
-
-
Zeidan, A.1
Javadov, S.2
Karmazyn, M.3
-
44
-
-
33847665035
-
Phenotype-specific inhibition of the vascular smooth muscle cell cycle by high glucose treatment
-
Zheng XL, Yuan SG, Peng DQ. 2007. Phenotype-specific inhibition of the vascular smooth muscle cell cycle by high glucose treatment. Diabetologia 50:881-890.
-
(2007)
Diabetologia
, vol.50
, pp. 881-890
-
-
Zheng, X.L.1
Yuan, S.G.2
Peng, D.Q.3
|