Improvement of poly(γ-glutamic acid) biosynthesis and quantitative metabolic flux analysis of a two-stage strategy for agitation speed control in the culture of Bacillus subtilis NX-2

Biotechnology and Bioprocess Engineering

Volumn 16, Issue 6, 2011, Pages 1144-1151

  Zhang, Dan ^a   Xu, Zongqi ^a   Xu, Hong ^a   Feng, Xiaohai ^a   Li, Sha ^a   Cai, Heng ^a   Wei, Yan ^a   Ouyang, Pingkai ^a  

^a NANJING TECH UNIVERSITY   (China)

Author keywords

Agitation speed; Enzyme activity; Metabolic flux; Poly( glutamic acid); Two stage control strategy

Indexed keywords

AMINO ACIDS; BACTERIOLOGY; BIOCHEMISTRY; CELL GROWTH; CELL PROLIFERATION; ENZYME ACTIVITY; GROWTH KINETICS; METABOLISM; SPEED CONTROL; SPEED REGULATORS;

AGITATION SPEED; GLUTAMATE DEHYDROGENASE; GLUTAMIC ACID; ISOCITRATE DEHYDROGENASE; MAXIMUM CONCENTRATIONS; METABOLIC FLUX; METABOLIC FLUX ANALYSIS; TWO-STAGE CONTROL STRATEGIES;

SPEED;

2 OXOGLUTARIC ACID; GLUTAMATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE; PTEROPTIN;

ANION TRANSPORT; ARTICLE; BACILLUS SUBTILIS; BACTERIAL CELL; BACTERIAL STRAIN; BACTERIUM CULTURE; BACTERIUM IDENTIFICATION; BIOSYNTHESIS; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; FERMENTATION TECHNIQUE; FLOW KINETICS; FLOW RATE; GEL PERMEATION CHROMATOGRAPHY; GROWTH RATE; INTERMETHOD COMPARISON; MOLECULAR DYNAMICS; NONHUMAN; QUANTITATIVE ANALYSIS;

BACILLUS SUBTILIS;

EID: 84862942071     PISSN: 12268372     EISSN: 19763816     Source Type: Journal    
DOI: 10.1007/s12257-011-0074-y     Document Type: Article

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