Transmembrane serine protease TADG-15 (ST14/Matriptase/MT-SP1): Expression and prognostic value in ovarian cancer

British Journal of Cancer

Volumn 92, Issue 2, 2005, Pages 278-283

  Tanimoto, H ^a   Shigemasa, K ^b   Tian, X ^b   Gu, L ^b   Beard, J B ^c   Sawasaki, T ^c   O'Brien, T J ^c  

^a National Hospital Organization Higashihiroshima Medical Center   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Immunohistochemistry; Ovarian cancer; Prognosis; Semiquantitative PCR; ST14; TADG 15

Indexed keywords

MATRIPTASE; MESSENGER RNA; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER GROWTH; CANCER STAGING; CANCER SURVIVAL; COMPARATIVE STUDY; DISEASE MARKER; DOWN REGULATION; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALIGNANT NEOPLASTIC DISEASE; OVARY CANCER; PATHOLOGY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION;

ADULT; AGED; AGED, 80 AND OVER; CELL MEMBRANE; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; OVARIAN NEOPLASMS; OVARY; POLYMERASE CHAIN REACTION; PROGNOSIS; RNA, MESSENGER; SERINE ENDOPEPTIDASES; TUMOR MARKERS, BIOLOGICAL;

EID: 14844304649     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6602320     Document Type: Article

References (27)

1. Diamandis EP, Yousef GM (2002) Human tissue kallikreins: a family of new cancer biomarkers. Clin Chem 48: 1198-1205
2. Duffy MJ (1992) The role of proteolytic enzymes in cancer invasion and metastasis. Clin Exp Metast 10: 145-155
3. Friedrich R, Fuentes-Prior P, Ong E, Coombs G, Hunter M, Oehler R, Pierson D, Gonzalez R, Huber R, Bode W, Madison EL (2002) Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase. J Biol Chem 277: 2160-2168
4. Goyal J, Smith KM, Cowan JM, Wazer DE, Lee SW, Band V (1998) The role for NES-1 serine protease as a novel tumor suppressor. Cancer Res 58: 4782-4786
5. Hooper JD, Clements JA, Quigley JP, Antalis TM (2001) Type II transmembrane serine proteases. J Biol Chem 276: 857-860
6. Kim MG, Chen C, Lyu MS, Cho EG, Park D, Kozak C, Schwartz RH (1999) Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains. Immunogenetics 49: 420-428
7. Lee SL, Dickson RB, Lin CY (2000) Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease. J Biol Chem 275: 36720-36725
8. Lin CY, Anders J, Johnson M, Sang QA, Dickson RB (1999) Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity. J Biol Chem 274: 18231-18236
9. Liotta LA, Steeg PS, Stetler-Stevenson WG (1991) Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 64: 327-336
10. Mignatti P, Robbins E, Rifkin DB (1986) Tumor invasion through the human amniotic membrane: requirement for a proteinase cascade. Cell 47: 487-498
11. Neurath H (1989) The diversity of proteolytic enzymes. In Proteolytic enzymes, Beynon RJ, Bond JS (eds) pp 1-13. Oxford, UK; IRL press
12. Oberst M, Anders J, Xie B, Singh B, Ossandon M, Johnson M, Dickson RB, Lin CY (2001) Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo. Am J Pathol 158: 1301-1311
13. Oberst MD, Johnson MD, Dickson RB, Lin CY, Singh B, Stewart M, Williams A, al-Nafussi A, Smyth JF, Gabra H, Sellar GC (2002) Expression of the serine protease matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: correction with clinical outcome and tumor clinicopathological parameters. Clin Cancer Res 8: 1101-1107
14. Shi YE, Torri J, Yieh L, Wellstein A, Lippman ME, Dickson RB (1993) Identification and characterization of a novel matrix-degrading protease from hormone-dependent human breast cancer cells. Cancer Res 53: 1409-1415
15. Shigemasa K, Hu C, West CM, Moon SH, Parham GP, Parmley TH, Korourian S, Baker VV, O'Brien TJ (1997) p21: a monitor of p53 dysfunction in ovarian neoplasia. Int J Gynecol Cancer 7: 296-303
16. Takeuchi T, Shuman MA, Craik CS (1999) Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue. Proc Natl Acad Sci USA 96: 11054-11061
17. Takeuchi T, Harris JL, Huang W, Yan KW, Coughlin SR, Craik CS (2000) Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates. J Biol Chem 275: 26333-26342
18. Tanimoto H, Yan Y, Clarke J, Korourian S, Shigemasa K, Parmley TH, Parham GP, O'Brien TJ (1997) Hepsin, a cell surface serine protease identified in hepatoma cells, is overexpressed in ovarian cancer. Cancer Res 57: 2884-2887
19. Tanimoto H, Underwood LJ, Wang Y, Clarke J, O'Brien TJ (1998) Cloning and expression of TADG-15, a novel serine protease expressed in ovarian cancer. Proc Am Assoc Cancer Res 39: 648
20. Tanimoto H, Underwood LJ, Shigemasa K, Yan Yan MS, Clarke J, Parmley TH, O'Brien TJ (1999) The stratum corneum chymotryptic enzyme that mediates shedding and desquamation of skin cells is highly overexpressed in ovarian tumor cells. Cancer 86: 2074-2082
21. Tanimoto H, Underwood LJ, Shigemasa K, Parmley TH, O'Brien TJ (2001a) Increased expression of protease M in ovarian tumors. Tumor Biol 22: 11-18
22. Tanimoto H, Underwood LJ, Wang Y, Shigemasa K, Parmley TH, O'Brien TJ (2001b) Ovarian tumor cells express a transmembrane serine protease: a potential candidate for early diagnosis and therapeutic intervention. Tumor Biol 22: 104-114
23. Tryggvason K, Höyhtyä M, Salo T (1987) Proteolytic degradation of extracellular matrix in tumor invasion. Biochem Biophys Acta 907: 191-217
24. Underwood LJ, Tanimoto H, Wang Y, Shigemasa K, Parmley TH, O'Brien TJ (1999) Cloning of tumor-associated differentially expressed gene-14, a novel serine protease overexpressed by ovarian carcinoma. Cancer Res 59: 4435-4439
25. Underwood LJ, Shigemasa K, Tanimoto H, Beard JB, Schneider EN, Wang Y, Parmley TH, O'Brien TJ (2000) Ovarian tumor cells express a novel multi-domain cell surface serine protease. Biochim Biophys Acta 1502: 337-350
26. Yousef GM, Magklara A, Chang A, Jung K, Katsaros D, Diamandis EP (2001) Cloning of a new member of the human kallikrein gene family, KLK14, which is down-regulated in different malignancies. Cancer Res 61: 3425-3431
27. Zhang Y, Cai X, Schlegelberger B, Zheng S (1998) Assignment of human putative tumor suppressor genes ST13 (alias SNC6) and ST14 (alias SNC19) to human chromosome bands 22q13 and 11q24→25 by in situ hybridization. Cytogenet Cell Genet 83: 56-57