Imaging of receptors for advanced glycation end products in experimental myocardial ischemia and reperfusion injury

JACC: Cardiovascular Imaging

Volumn 5, Issue 1, 2012, Pages 59-67

  Tekabe, Yared ^a   Luma, Joane ^a   Li, Qing ^a   Schmidt, Ann Marie ^a,b   Ramasamy, Ravichandran ^a,b   Johnson, Lynne L ^a  

^a NewYork Presbyterian Hospital   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

molecular imaging; myocardial infarction; nano SPECT CT; RAGE

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; ADVANCED GLYCATION END PRODUCT RECEPTOR ANTIBODY TC 99M; CASPASE 3; IMMUNOGLOBULIN F(AB')2 FRAGMENT; THALLIUM 201; TRACER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART SCINTISCANNING; IMAGE ANALYSIS; IMAGE ENHANCEMENT; IMAGE PROCESSING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REPERFUSION INJURY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; WILD TYPE;

ANIMALS; APOPTOSIS; DISEASE MODELS, ANIMAL; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOGLOBULIN FAB FRAGMENTS; MALE; MICE; MICE, INBRED C57BL; MOLECULAR IMAGING; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; RECEPTORS, IMMUNOLOGIC; TECHNETIUM; TIME FACTORS;

EID: 84862909204     PISSN: 1936878X     EISSN: 18767591     Source Type: Journal    
DOI: 10.1016/j.jcmg.2011.09.016     Document Type: Article

References (18)

1. L.G. Bucciarelli, M. Kaneko, A. Ananthakrishman Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury Circulation 113 2006 1226 1234
2. M. Neper, A.M. Schmidt, J. Brett Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins J Biol Chem 267 1992 14998 15004
3. A.M. Schmidt, M. Hasu, D. Popov The receptor for advanced glycation end products (AGEs) has a central role in vessel wall interactions and gene activation in response to AGEs in the intravascular space Proc Natl Acad Sci U S A 91 1994 8807 8811
4. T. Kislinger, C. Fu, B. Huber N-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression J Biol Chem 44 1999 31740 31749
5. T. Arumugam, D.M. Simeone, A.M. Schmidt S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE) J Biol Chem 279 2004 5059 5065 (Pubitemid 38220521)
6. M.A. Hofmann, S. Drury, C. Fu RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides Cell 97 1999 889 901 (Pubitemid 29375048)
7. Y. Tekabe, J. Luma, A. Einstein A novel monoclonal antibody for RAGE-directed imaging identifies accelerated atherosclerosis in diabetes J Nucl Med 51 2010 92 97
8. Y. Tekabe, Q. Li, R. Rosario Development of receptor for advanced glycation end products-directed imaging of atherosclerotic plaque in a murine model of spontaneous atherosclerosis Circ Cardiovasc Imaging 1 2008 212 219
9. J. Brett, A.M. Schmidt, S. Du Yan Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues Am J Pathol 143 1993 1699 1722
10. A.M. Schmidt, M. Hasu, D. Popov Receptor for advanced glycation end products (AGEs) has a central role in vessel wall interactions and gene activation in response to AGEs in the intravascular space Proc Natl Acad Sci U S A 91 1994 8807 8811
11. L.G. Bucciarelli, R. Ananthakrishnan, Y.C. Hwang RAGE and modulation of ischemic injury in the diabetic myocardium Diabetes 57 2008 1941 1951
12. A. Aleshin, R. Ananthakrishman, Q. Li RAGE modulates myocardial injury consequent to LAD infarction via impact on JNK and STAT signaling in a murine model Am J Physiol Heart Circ Physiol 294 2008 H1823 H1832
13. Y.C. Hwang, S. Shaw, M. Kaneko Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury FASEB J 19 2005 795 797 (Pubitemid 40617387)
14. J.J. Jocoby, A. Kalinowski, M.G. Liu Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age Proc Natl Acad Sci U S A 100 2003 12929 12934 (Pubitemid 37340002)
15. R.A. Kaiser, Q. Liang, O.F. Bueno Genetic inhibition or activation of JNK1/2 each protect the myocardium from ischemia-reperfusion-induced cell death in vivo J Biol Chem 23 2005 32602 32608 (Pubitemid 41368302)
16. E. Mascareno, M. El-Shafei, N. Maulik JAK/STAT signaling is associated with cardiac dysfunction during ischemia and reperfusion Circulation 104 2001 325 329 (Pubitemid 32666955)
17. L. Shang, R. Ananthakrishnan, Q. Li RAGE modulates hypoxia/regeneration injury in adult murine cardiomyocytes via JNK and GSK-3β signaling pathways PLoS ONE 5 2010 e10092
18. S. Zeng, N. Feirt, M. Goldstein Blockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury in the liver in mice Hepatology 39 2004 422 432 (Pubitemid 38222183)