-
1
-
-
0034082239
-
The influence of natural products upon drug discovery
-
Newman DJ, Cragg GM, Snader KM. The influence of natural products upon drug discovery. Nat Prod Rep 2000;17:215-34.
-
(2000)
Nat Prod Rep
, vol.17
, pp. 215-234
-
-
Newman, D.J.1
Cragg, G.M.2
Snader, K.M.3
-
2
-
-
33644535147
-
Natural products-the future scaffolds for novel antibiotics?
-
Butler MS, Buss AD. Natural products-the future scaffolds for novel antibiotics? Biochem. Pharmacol. 2006;71:919-29.
-
(2006)
Biochem Pharmacol.
, vol.71
, pp. 919-929
-
-
Butler, M.S.1
Buss, A.D.2
-
3
-
-
0001581071
-
Antibiotic substances from basidiomycetes.8. pleurotus-multilus (fr.) Sacc. And pleurotuspasseckerianus pilat
-
Kavanagh F, Hervey A, Robbins WJ. Antibiotic substances from basidiomycetes.8. pleurotus-multilus (fr.) Sacc. And pleurotuspasseckerianus pilat. Proc. Natl. Acad. Sci. U. S. A. 1951;37:570-4.
-
(1951)
Proc. Natl. Acad. Sci. U. S. A.
, vol.37
, pp. 570-574
-
-
Kavanagh, F.1
Hervey, A.2
Robbins, W.J.3
-
4
-
-
0016785248
-
Antimicrobial activities of 81.723 hfu, a new pleuromutilin derivative
-
Drews J, Georgopoulos A, Laber G, Schutze E, Unger J. Antimicrobial activities of 81.723 hfu, a new pleuromutilin derivative. Antimicrob Agents Ch 1975;7:507-16.
-
(1975)
Antimicrob Agents Ch
, vol.7
, pp. 507-516
-
-
Drews, J.1
Georgopoulos, A.2
Laber, G.3
Schutze, E.4
Unger, J.5
-
5
-
-
0016668072
-
Mode of action of pleuromutilin derivatives-location and properties of pleuromutilin binding-site on escherichia-coli ribosomes
-
Hogenauer G. Mode of action of pleuromutilin derivatives-location and properties of pleuromutilin binding-site on escherichia-coli ribosomes. Eur J Biochem 1975;52:93-8.
-
(1975)
Eur J Biochem
, vol.52
, pp. 93-98
-
-
Hogenauer, G.1
-
6
-
-
0017131492
-
New pleuromutilin derivatives with enhanced antimicrobial activity. I. Synthesis
-
Egger H, Reinshagen H. New pleuromutilin derivatives with enhanced antimicrobial activity. I. Synthesis. J. Antibiot. 1976;29:915-22.
-
(1976)
J. Antibiot.
, vol.29
, pp. 915-922
-
-
Egger, H.1
Reinshagen, H.2
-
7
-
-
0017098675
-
New pleuromutilin derivatives with enhanced antimicrobial activity.2. structure-activity correlations
-
Egger H, Reinshagen H. New pleuromutilin derivatives with enhanced antimicrobial activity.2. structure-activity correlations. J Antibiot 1976;29:923-7.
-
(1976)
J Antibiot
, vol.29
, pp. 923-927
-
-
Egger, H.1
Reinshagen, H.2
-
8
-
-
0034501311
-
Pleuromutilin antibiotics
-
Hunt E. Pleuromutilin antibiotics. Drugs Future 2000;25:1163-8.
-
(2000)
Drugs Future
, vol.25
, pp. 1163-1168
-
-
Hunt, E.1
-
9
-
-
9644281855
-
Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin
-
Schluenzen F, Pyetan E, Fucini P, Yonath A, Harms JM. Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin. Mol. Microbiol. 2004;54:1287-94.
-
(2004)
Mol. Microbiol.
, vol.54
, pp. 1287-1294
-
-
Schluenzen, F.1
Pyetan, E.2
Fucini, P.3
Yonath, A.4
Harms, J.M.5
-
10
-
-
0030831816
-
In vitro susceptibilities of recent field isolates of Mycoplasma hyopneumoniae and Mycoplasma hyosynoviae to valnemulin (Econor), tiamulin and enrofloxacin and the in vitro development of resistance to certain antimicrobial agents in Mycoplasma hyopneumoniae
-
Hannan PCT, Windsor HM, Ripley PH. In vitro susceptibilities of recent field isolates of Mycoplasma hyopneumoniae and Mycoplasma hyosynoviae to valnemulin (Econor), tiamulin and enrofloxacin and the in vitro development of resistance to certain antimicrobial agents in Mycoplasma hyopneumoniae. Res Vet Sci 1997;63:157-60.
-
(1997)
Res Vet Sci
, vol.63
, pp. 157-160
-
-
Hannan, P.C.T.1
Windsor, H.M.2
Ripley, P.H.3
-
11
-
-
74049156420
-
Mutilins derivatives: From veterinary to human-used antibiotics
-
Hu C, Zou Y. Mutilins derivatives: from veterinary to human-used antibiotics. Mini-Rev. Med. Chem. 2009;9:1397-406.
-
(2009)
Mini-Rev. Med. Chem.
, vol.9
, pp. 1397-1406
-
-
Hu, C.1
Zou, Y.2
-
12
-
-
34147163566
-
Pleuromutilin antibacterial agents: Patent review 2001-2006
-
Phillips OA, Sharaf LH. Pleuromutilin antibacterial agents: patent review 2001-2006. Expert Opin. Ther. Pat. 2007;17:429-35.
-
(2007)
Expert Opin. Ther. Pat.
, vol.17
, pp. 429-435
-
-
Phillips, O.A.1
Sharaf, L.H.2
-
13
-
-
41849127062
-
Water-Soluble Pleuromutilin Derivative with Excellent in vitro and in vivo Antibacterial Activity against Gram-Positive Pathogens
-
Hirokawa Y, Kinoshita H, Tanaka T, Nakata K, Kitadai N, Fujimoto K, et al. Water-Soluble Pleuromutilin Derivative with Excellent in vitro and in vivo Antibacterial Activity against Gram-Positive Pathogens. J. Med. Chem. 2008;51:1991-4.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 1991-1994
-
-
Hirokawa, Y.1
Kinoshita, H.2
Tanaka, T.3
Nakata, K.4
Kitadai, N.5
Fujimoto, K.6
-
14
-
-
57749092778
-
Pleuromutilin derivatives having a purine ring. Part 3: Synthesis and antibacterial activity of novel compounds possessing a piperazine ring spacer
-
Hirokawa Y, Kinoshita H, Tanaka T, Nakamura T, Fujimoto K, Kashimoto S, et al. Pleuromutilin derivatives having a purine ring. Part 3: Synthesis and antibacterial activity of novel compounds possessing a piperazine ring spacer. Bioorg. Med. Chem. Lett. 2009;19:175-9.
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 175-179
-
-
Hirokawa, Y.1
Kinoshita, H.2
Tanaka, T.3
Nakamura, T.4
Fujimoto, K.5
Kashimoto, S.6
-
15
-
-
44649173661
-
Pleuromutilin derivatives having a purine ring. Part 1: New compounds with promising antibacterial activity against resistant Gram-positive pathogens
-
Hirokawa Y, Kinoshita H, Tanaka T, Nakamura T, Fujimoto K, Kashimoto S, et al. Pleuromutilin derivatives having a purine ring. Part 1: New compounds with promising antibacterial activity against resistant Gram-positive pathogens. Bioorg. Med. Chem. Lett. 2008;18:3556-61.
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 3556-3561
-
-
Hirokawa, Y.1
Kinoshita, H.2
Tanaka, T.3
Nakamura, T.4
Fujimoto, K.5
Kashimoto, S.6
-
16
-
-
57749114472
-
Pleuromutilin derivatives having a purine ring. Part 2: Influence of the central spacer on the antibacterial activity against Gram-positive pathogens
-
Hirokawa Y, Kinoshita H, Tanaka T, Nakamura T, Fujimoto K, Kashimoto S, et al. Pleuromutilin derivatives having a purine ring. Part 2: Influence of the central spacer on the antibacterial activity against Gram-positive pathogens. Bioorg Med Chem Lett 2009;19:170-4.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 170-174
-
-
Hirokawa, Y.1
Kinoshita, H.2
Tanaka, T.3
Nakamura, T.4
Fujimoto, K.5
Kashimoto, S.6
-
17
-
-
72949090845
-
A Dialdehyde Cyclization Cascade: An Approach to Pleuromutilin
-
Helm MD, Da Silva M, Sucunza D, Findley TJK, Procter DJ. A Dialdehyde Cyclization Cascade: An Approach to Pleuromutilin. Angew. Chem., Int. Ed. 2009;48:9315-7, S9311-5.
-
(2009)
Angew. Chem., Int. Ed.
, vol.48
-
-
Helm, M.D.1
da Silva, M.2
Sucunza, D.3
Findley, T.J.K.4
Procter, D.J.5
-
18
-
-
77649153351
-
The pleuromutilin antibiotics: A new class for human use
-
M SD
-
Rodger N, M SD. The pleuromutilin antibiotics: a new class for human use. Curr Opin Investig Drugs 2010;11:182-91.
-
(2010)
Curr Opin Investig Drugs
, vol.11
, pp. 182-191
-
-
Rodger, N.1
-
19
-
-
0019982412
-
Total synthesis of (+-)-pleuromutilin
-
Gibbons EG. Total synthesis of (+-)-pleuromutilin. J. Am. Chem. Soc. 1982;104:1767-9.
-
(1982)
J. Am. Chem. Soc.
, vol.104
, pp. 1767-1769
-
-
Gibbons, E.G.1
-
20
-
-
0000509501
-
Synthetic studies directed toward naturally occurring cyclooctanoids. 2. A stereocontrolled assembly of (+-)-pleuromutilin via a remarkable sterically demanding oxy-Cope rearrangement
-
Jr. Boeckman RK, Springer DM, Alessi TR. Synthetic studies directed toward naturally occurring cyclooctanoids. 2. A stereocontrolled assembly of (+-)-pleuromutilin via a remarkable sterically demanding oxy-Cope rearrangement. J. Am. Chem. Soc. 1989;111:8284-6.
-
(1989)
J. Am. Chem. Soc.
, vol.111
, pp. 8284-8286
-
-
Boeckman Jr., R.K.1
Springer, D.M.2
Alessi, T.R.3
-
21
-
-
78751544589
-
A concise synthesis of the molecular framework of pleuromutilin
-
Liu J, Lotesta SD, Sorensen EJ. A concise synthesis of the molecular framework of pleuromutilin. Chem Commun 2011;47:1500-2.
-
(2011)
Chem Commun
, vol.47
, pp. 1500-1502
-
-
Liu, J.1
Lotesta, S.D.2
Sorensen, E.J.3
-
22
-
-
79952756337
-
A stereoselective, Sm(II)-mediated approach to decorated cis-hydrindanes: Synthetic studies on faurinone and pleuromutilin
-
Findley TJK, Sucunza D, Miller LC, Helm MD, Helliwell M, Davies DT, et al. A stereoselective, Sm(II)-mediated approach to decorated cis-hydrindanes: synthetic studies on faurinone and pleuromutilin. Organic & Biomolecular Chemistry 2011;9:2433-51.
-
(2011)
Organic & Biomolecular Chemistry
, vol.9
, pp. 2433-2451
-
-
Findley, T.J.K.1
Sucunza, D.2
Miller, L.C.3
Helm, M.D.4
Helliwell, M.5
Davies, D.T.6
-
23
-
-
0017234295
-
Pleuromutilins. Fermentation, structure and biosynthesis
-
Knauseder F, Brandl E. Pleuromutilins. Fermentation, structure and biosynthesis. J. Antibiot. 1976;29:125-31.
-
(1976)
J. Antibiot.
, vol.29
, pp. 125-131
-
-
Knauseder, F.1
Brandl, E.2
-
25
-
-
0017260288
-
Studies on pleuromutilin and some of its derivatives
-
Riedl K. Studies on pleuromutilin and some of its derivatives. J. Antibiot. 1976;29:132-9.
-
(1976)
J. Antibiot.
, vol.29
, pp. 132-139
-
-
Riedl, K.1
-
26
-
-
0023123949
-
Chemistry of pleuromutilins. 12. A cyclopropyl conjugated system within the tricyclic skeleton of the diterpene pleuromutilin: Formation and synthetic use
-
Berner H, Vyplel H, Schulz G. Chemistry of pleuromutilins. 12. A cyclopropyl conjugated system within the tricyclic skeleton of the diterpene pleuromutilin: formation and synthetic use. Tetrahedron 1987;43:765-70.
-
(1987)
Tetrahedron
, vol.43
, pp. 765-770
-
-
Berner, H.1
Vyplel, H.2
Schulz, G.3
-
27
-
-
0009470894
-
Chemistry of pleuromutilin. Part 11. Inversion of configuration of the vinyl group at carbon 12 by reversible retro-ene cleavage
-
Berner H, Vyplel H, Schulz G, Schneider H. Chemistry of pleuromutilin. Part 11. Inversion of configuration of the vinyl group at carbon 12 by reversible retro-ene cleavage. Monatsh. Chem. 1986;117:1073-80.
-
(1986)
Monatsh. Chem.
, vol.117
, pp. 1073-1080
-
-
Berner, H.1
Vyplel, H.2
Schulz, G.3
Schneider, H.4
-
28
-
-
0021351266
-
Chemistry of pleuromutilin. VI. Comparative study of the carbon-13 NMR spectra of the tricyclic diterpene mutilin and a series of mutilin derivatives
-
Schulz G, Berner H. Chemistry of pleuromutilin. VI. Comparative study of the carbon-13 NMR spectra of the tricyclic diterpene mutilin and a series of mutilin derivatives. Tetrahedron 1984;40:905-17.
-
(1984)
Tetrahedron
, vol.40
, pp. 905-917
-
-
Schulz, G.1
Berner, H.2
-
29
-
-
0009528963
-
Chemistry of pleuromutilin. VIII. Functionalization at C-13 by intramolecular nitrene insertion. Synthesis of 14-O-[(3-amino-1,2,4-triazol-5-yl)thioacetyl]-13-amino-19,20-dihydromutilin hydrochloride
-
Berner H, Vyplel H, Schulz G, Stuchlik P. Chemistry of pleuromutilin. VIII. Functionalization at C-13 by intramolecular nitrene insertion. Synthesis of 14-O-[(3-amino-1,2,4-triazol-5-yl)thioacetyl]-13-amino-19,20-dihydromutilin hydrochloride. Tetrahedron 1984;40:919-23.
-
(1984)
Tetrahedron
, vol.40
, pp. 919-923
-
-
Berner, H.1
Vyplel, H.2
Schulz, G.3
Stuchlik, P.4
-
30
-
-
0001634402
-
Chemistry of pleuromutilins. IX. Inversion of configuration of the methyl group at carbon 6 in the tricyclic skeleton of the diterpene pleuromutilin
-
Berner H, Vyplel H, Schulz G, Stuchlik P. Chemistry of pleuromutilins. IX. Inversion of configuration of the methyl group at carbon 6 in the tricyclic skeleton of the diterpene pleuromutilin. Monatsh. Chem. 1983;114:1125-36.
-
(1983)
Monatsh. Chem.
, vol.114
, pp. 1125-1136
-
-
Berner, H.1
Vyplel, H.2
Schulz, G.3
Stuchlik, P.4
-
31
-
-
0009470774
-
Chemistry of pleuromutilins. VII. Base-induced transannular 1,4-hydride shift in 8-substituted pleuromutilin derivatives
-
Berner H, Vyplel H, Schulz G. Chemistry of pleuromutilins. VII. Base-induced transannular 1,4-hydride shift in 8-substituted pleuromutilin derivatives. Monatsh. Chem. 1983;114:501-7.
-
(1983)
Monatsh. Chem.
, vol.114
, pp. 501-507
-
-
Berner, H.1
Vyplel, H.2
Schulz, G.3
-
32
-
-
0000795201
-
Chemistry of pleuromutilin. IV. Synthesis of 14-O-acetyl-8alpha-hydroxymutilin
-
Berner H, Vyplel H, Schulz G, Stuchlik P. Chemistry of pleuromutilin. IV. Synthesis of 14-O-acetyl-8alpha-hydroxymutilin. Tetrahedron 1983;39:1317-21.
-
(1983)
Tetrahedron
, vol.39
, pp. 1317-1321
-
-
Berner, H.1
Vyplel, H.2
Schulz, G.3
Stuchlik, P.4
-
33
-
-
0019720205
-
Chemistry of pleuromutilins. Part 3. Synthesis of 14-O-acetyl-19,20-dihydro-A-nor-mutilin
-
Berner H, Schulz G, Fischer G. Chemistry of pleuromutilins. Part 3. Synthesis of 14-O-acetyl-19,20-dihydro-A-nor-mutilin. Monatsh. Chem. 1981;112:1441-50.
-
(1981)
Monatsh. Chem.
, vol.112
, pp. 1441-1450
-
-
Berner, H.1
Schulz, G.2
Fischer, G.3
-
34
-
-
0009473740
-
Chemistry of pleuromutilins. II. Synthesis of 12-devinylpleuromutilins
-
Berner H, Schulz G, Schneider H. Chemistry of pleuromutilins. II. Synthesis of 12-devinylpleuromutilins. Tetrahedron 1981;37:915-9.
-
(1981)
Tetrahedron
, vol.37
, pp. 915-919
-
-
Berner, H.1
Schulz, G.2
Schneider, H.3
-
35
-
-
0009501175
-
Synthesis of an AB-transannulated derivative of the tricyclic diterpene pleuromutilin through an intramolecular 1,5-hydride shift
-
Berner H, Schulz G, Schneider H. Synthesis of an AB-transannulated derivative of the tricyclic diterpene pleuromutilin through an intramolecular 1,5-hydride shift. Tetrahedron 1980;36:1807-11.
-
(1980)
Tetrahedron
, vol.36
, pp. 1807-1811
-
-
Berner, H.1
Schulz, G.2
Schneider, H.3
-
37
-
-
77649165400
-
In vitro Antibacterial Spectrum of BC-3205, a Novel Pleuromutilin Derivative for Oral Use in Humans
-
Biedenbach DJ, Jones RN, Ivezic-Schoenfeld Z, Paukner S, Novak R. In vitro Antibacterial Spectrum of BC-3205, a Novel Pleuromutilin Derivative for Oral Use in Humans. Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy 2009;49:197.
-
(2009)
Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy
, vol.49
, pp. 197
-
-
Biedenbach, D.J.1
Jones, R.N.2
Ivezic-Schoenfeld, Z.3
Paukner, S.4
Novak, R.5
-
38
-
-
77649165400
-
In vitro Antibacterial Spectrum of BC-7013, a Novel Pleuromutilin Derivative for Topical Use in Humans
-
Biedenbach DJ, Jones RN, Ivezic-Schoenfeld Z, Paukner S, Novak R. In vitro Antibacterial Spectrum of BC-7013, a Novel Pleuromutilin Derivative for Topical Use in Humans. Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy 2009;49:199.
-
(2009)
Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy
, vol.49
, pp. 199
-
-
Biedenbach, D.J.1
Jones, R.N.2
Ivezic-Schoenfeld, Z.3
Paukner, S.4
Novak, R.5
-
40
-
-
0016203943
-
The mode of action of pleuromutilin derivatives. Effect on cell-free polypeptide synthesis
-
Hodgin LA, Hogenauer G. The mode of action of pleuromutilin derivatives. Effect on cell-free polypeptide synthesis. Eur J Biochem 1974;47:527-33.
-
(1974)
Eur J Biochem
, vol.47
, pp. 527-533
-
-
Hodgin, L.A.1
Hogenauer, G.2
-
41
-
-
0016668072
-
The mode of action of pleuromutilin derivatives. Location and properties of the pleuromutilin binding site on Escherichia coli ribosomes
-
Hogenauer G. The mode of action of pleuromutilin derivatives. Location and properties of the pleuromutilin binding site on Escherichia coli ribosomes. Eur J Biochem 1975;52:93-8.
-
(1975)
Eur J Biochem
, vol.52
, pp. 93-98
-
-
Hogenauer, G.1
-
42
-
-
0019419884
-
Ribosomal binding region for the antibiotic tiamulin: Stoichiometry, subunit location, and affinity for various analogs
-
Hogenauer G, Ruf C. Ribosomal binding region for the antibiotic tiamulin: stoichiometry, subunit location, and affinity for various analogs. Antimicrob Agents Chemother 1981;19:260-5.
-
(1981)
Antimicrob Agents Chemother
, vol.19
, pp. 260-265
-
-
Hogenauer, G.1
Ruf, C.2
-
43
-
-
0018162344
-
The effects of tiamulin, a semisynthetic pleuromutilin derivative, on bacterial polypeptide chain initiation
-
Dornhelm P, Hogenauer G. The effects of tiamulin, a semisynthetic pleuromutilin derivative, on bacterial polypeptide chain initiation. Eur J Biochem 1978;91:465-73.
-
(1978)
Eur J Biochem
, vol.91
, pp. 465-473
-
-
Dornhelm, P.1
Hogenauer, G.2
-
44
-
-
0035788806
-
The pleuromutilin drugs tiamulin and valnemulin bind to the RNA at the peptidyl transferase centre on the ribosome
-
Poulsen SM, Karlsson M, Johansson LB, Vester B. The pleuromutilin drugs tiamulin and valnemulin bind to the RNA at the peptidyl transferase centre on the ribosome. Mol. Microbiol. 2001;41:1091-9.
-
(2001)
Mol. Microbiol.
, vol.41
, pp. 1091-1099
-
-
Poulsen, S.M.1
Karlsson, M.2
Johansson, L.B.3
Vester, B.4
-
45
-
-
34248326491
-
Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity
-
Davidovich C, Bashan A, Auerbach-Nevo T, Yaggie RD, Gontarek RR, Yonath A. Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity. Proc. Natl. Acad. Sci. U. S. A. 2007;104:4291-6.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 4291-4296
-
-
Davidovich, C.1
Bashan, A.2
Auerbach-Nevo, T.3
Yaggie, R.D.4
Gontarek, R.R.5
Yonath, A.6
-
46
-
-
3242712966
-
Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin
-
Harms JM, Schlunzen F, Fucini P, Bartels H, Yonath A. Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin. BMC Biol 2004;2:4-10.
-
(2004)
BMC Biol
, vol.2
, pp. 4-10
-
-
Harms, J.M.1
Schlunzen, F.2
Fucini, P.3
Bartels, H.4
Yonath, A.5
-
47
-
-
2542445275
-
Ribosomal crystallography: A flexible nucleotide anchoring tRNA translocation facilitates peptide-bond formation, chirality discrimination and antibiotics synergism
-
Agmon I, Amit M, Auerbach T, Bashan A, Baram D, Bartels H, et al. Ribosomal crystallography: a flexible nucleotide anchoring tRNA translocation facilitates peptide-bond formation, chirality discrimination and antibiotics synergism. Febs Lett 2004;567:20-6.
-
(2004)
Febs Lett
, vol.567
, pp. 20-26
-
-
Agmon, I.1
Amit, M.2
Auerbach, T.3
Bashan, A.4
Baram, D.5
Bartels, H.6
-
48
-
-
0036177483
-
A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits
-
Schmeing TM, Seila AC, Hansen JL, Freeborn B, Soukup JK, Scaringe SA, et al. A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits. Nature Structural Biology 2002;9:225-30.
-
(2002)
Nature Structural Biology
, vol.9
, pp. 225-230
-
-
Schmeing, T.M.1
Seila, A.C.2
Hansen, J.L.3
Freeborn, B.4
Soukup, J.K.5
Scaringe, S.A.6
-
49
-
-
33745205638
-
Conserved loop sequence of Helix 69 in Escherichia coli 23 S rRNA is involved in A-site tRNA binding and translational fidelity
-
Hirabayashi N, Sato NS, Suzuki T. Conserved loop sequence of Helix 69 in Escherichia coli 23 S rRNA is involved in A-site tRNA binding and translational fidelity. J Biol Chem 2006;281:17203-11.
-
(2006)
J Biol Chem
, vol.281
, pp. 17203-17211
-
-
Hirabayashi, N.1
Sato, N.S.2
Suzuki, T.3
-
50
-
-
33750600405
-
Biochemical characterization of the interactions of the novel pleuromutilin derivative retapamulin with bacterial ribosomes
-
Yan K, Madden L, Choudhry AE, Voigt CS, Copeland RA, Gontarek RR. Biochemical characterization of the interactions of the novel pleuromutilin derivative retapamulin with bacterial ribosomes. Antimicrob Agents Ch 2006;50:3875-81.
-
(2006)
Antimicrob Agents Ch
, vol.50
, pp. 3875-3881
-
-
Yan, K.1
Madden, L.2
Choudhry, A.E.3
Voigt, C.S.4
Copeland, R.A.5
Gontarek, R.R.6
-
51
-
-
0024334898
-
Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites
-
Moazed D, Noller HF. Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites. Cell 1989;57;585-97.
-
(1989)
Cell
, vol.57
, pp. 585-597
-
-
Moazed, D.1
Noller, H.F.2
-
52
-
-
33645767206
-
Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center
-
Long KS, Hansen LH, Jakobsen L, Vester B. Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center. Antimicrob Agents Ch 2006;50:1458-62.
-
(2006)
Antimicrob Agents Ch
, vol.50
, pp. 1458-1462
-
-
Long, K.S.1
Hansen, L.H.2
Jakobsen, L.3
Vester, B.4
-
53
-
-
0035015698
-
Pleuromutilins. Part 1. The identification of novel mutilin 14-carbamates
-
G B, W B, D C, D HJ, E H, J PM, et al. Pleuromutilins. Part 1. The identification of novel mutilin 14-carbamates. Bioorg Med Chem 2001;9:1221-31.
-
(2001)
Bioorg Med Chem
, vol.9
, pp. 1221-1231
-
-
G, B.1
W, B.2
D, C.3
D, H.J.4
E, H.5
J, P.M.6
-
54
-
-
0038363790
-
Synthesis and activity of a C-8 keto pleuromutilin derivative
-
Springer DM, Sorenson ME, Huang S, Connolly TP, Bronson JJ, Matson JA, et al. Synthesis and activity of a C-8 keto pleuromutilin derivative. Bioorg. Med. Chem. Lett. 2003;13:1751-3.
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 1751-1753
-
-
Springer, D.M.1
Sorenson, M.E.2
Huang, S.3
Connolly, T.P.4
Bronson, J.J.5
Matson, J.A.6
-
55
-
-
0016683363
-
In vivo efficacy of 81.723 hfu, a new pleuromutilin derivative against experimentally induced airsacculitis in chicks and turkey poults
-
Laber G, Schutze E. In vivo efficacy of 81.723 hfu, a new pleuromutilin derivative against experimentally induced airsacculitis in chicks and turkey poults. Antimicrob Agents Chemother 1975;7;517-21.
-
(1975)
Antimicrob Agents Chemother
, vol.7
, pp. 517-521
-
-
Laber, G.1
Schutze, E.2
-
56
-
-
0017512693
-
Prophylactical and therapeutical efficacy of Tiamuline in mycoplasmosis of chickens and turkeys
-
Stipkovits L, Laber G, Schultze E. Prophylactical and therapeutical efficacy of Tiamuline in mycoplasmosis of chickens and turkeys. Poult Sci 1977;56;1209-15.
-
(1977)
Poult Sci
, vol.56
, pp. 1209-1215
-
-
Stipkovits, L.1
Laber, G.2
Schultze, E.3
-
57
-
-
0018029783
-
Effect of tiamulin in chickens and turkeys infected experimentally with avian Mycoplasma
-
Baughn CO, Alpaugh WC, Linkenheimer WH, Maplesden DC. Effect of tiamulin in chickens and turkeys infected experimentally with avian Mycoplasma. Avian Dis 1978;22;620-6.
-
(1978)
Avian Dis
, vol.22
, pp. 620-626
-
-
Baughn, C.O.1
Alpaugh, W.C.2
Linkenheimer, W.H.3
Maplesden, D.C.4
-
58
-
-
0036281221
-
Evaluation of tiamulin and lincomycin for the treatment of broiler breeders experimentally infected with the intestinal spirochaete Brachyspira pilosicoli
-
Stephens CP, Hampson DJ. Evaluation of tiamulin and lincomycin for the treatment of broiler breeders experimentally infected with the intestinal spirochaete Brachyspira pilosicoli. Avian Pathol 2002;31:299-304.
-
(2002)
Avian Pathol
, vol.31
, pp. 299-304
-
-
Stephens, C.P.1
Hampson, D.J.2
-
59
-
-
0036282118
-
Influence of in-feed zinc bacitracin and tiamulin treatment on experimental avian intestinal spirochaetosis caused by Brachyspira intermedia
-
Hampson DJ, Oxberry SL, Stephens CP. Influence of in-feed zinc bacitracin and tiamulin treatment on experimental avian intestinal spirochaetosis caused by Brachyspira intermedia. Avian Pathol 2002;31:285-91.
-
(2002)
Avian Pathol
, vol.31
, pp. 285-291
-
-
Hampson, D.J.1
Oxberry, S.L.2
Stephens, C.P.3
-
60
-
-
33745054151
-
Treatment of a field case of avian intestinal spirochaetosis caused by Brachyspira pilosicoli with tiamulin
-
Burch D, Harding C, Alvarez R, Valks M. Treatment of a field case of avian intestinal spirochaetosis caused by Brachyspira pilosicoli with tiamulin. Avian Pathol 2006;35:211-6.
-
(2006)
Avian Pathol
, vol.35
, pp. 211-216
-
-
Burch, D.1
Harding, C.2
Alvarez, R.3
Valks, M.4
-
61
-
-
84862975063
-
In vivo efficacy of the novel oral pleuromutilin, SB-264128
-
Toronto, Ontario, Canada
-
Satterfield J, Berry V, Singley C, Hunt E, Woodnutt G. In vivo efficacy of the novel oral pleuromutilin, SB-264128. 40th Interscience Conference on Antimicrobial Agents and Chemotherapy. Toronto, Ontario, Canada; 2000, p. 234.
-
(2000)
40th Interscience Conference on Antimicrobial Agents and Chemotherapy.
, pp. 234
-
-
Satterfield, J.1
Berry, V.2
Singley, C.3
Hunt, E.4
Woodnutt, G.5
-
62
-
-
84862936161
-
In vitro activity of the novel pleuromutilin SB-264128 against organisms associated with respiratory tract infection
-
Toronto, Ontario, Canada
-
Rittenhouse SF, Moore TD, Woodnutt G, Hunt E. In vitro activity of the novel pleuromutilin SB-264128 against organisms associated with respiratory tract infection. 40th Interscience Conference on Antimicrobial Agents and Chemotherapy. Toronto, Ontario, Canada; 2000, p. 234.
-
(2000)
40th Interscience Conference on Antimicrobial Agents and Chemotherapy.
, pp. 234
-
-
Rittenhouse, S.F.1
Moore, T.D.2
Woodnutt, G.3
Hunt, E.4
-
63
-
-
84862950232
-
Efficacy of Retapamulin (RE) Administered Topically against Methicillin, Mupirocin and Multi-Drug Resistant Strains of S-aureus in a Murine Wound Infection Model
-
Washington, DC, USA
-
Singley C, Hoover J, Page R, Payne D, Rittenhouse S. Efficacy of Retapamulin (RE) Administered Topically against Methicillin, Mupirocin and Multi-Drug Resistant Strains of S-aureus in a Murine Wound Infection Model. 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, DC, USA; 2005, p. 2070.
-
(2005)
45th Interscience Conference on Antimicrobial Agents and Chemotherapy.
, pp. 2070
-
-
Singley, C.1
Hoover, J.2
Page, R.3
Payne, D.4
Rittenhouse, S.5
-
64
-
-
33646270171
-
Retapamulin: Pleuromutilin antibiotic
-
Boyd B, Castaner J. Retapamulin: pleuromutilin antibiotic. Drugs Future 2006;31:107-13.
-
(2006)
Drugs Future
, vol.31
, pp. 107-113
-
-
Boyd, B.1
Castaner, J.2
-
65
-
-
50249167106
-
A Click Chemistry Approach to Pleuromutilin Conjugates with Nucleosides or Acyclic Nucleoside Derivatives and Their Binding to the Bacterial Ribosome
-
Lolk L, Pohlsgaard J, Jepsen AS, Hansen LH, Nielsen H, Steffansen SI, et al. A Click Chemistry Approach to Pleuromutilin Conjugates with Nucleosides or Acyclic Nucleoside Derivatives and Their Binding to the Bacterial Ribosome. J. Med. Chem. 2008;51:4957-67.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 4957-4967
-
-
Lolk, L.1
Pohlsgaard, J.2
Jepsen, A.S.3
Hansen, L.H.4
Nielsen, H.5
Steffansen, S.I.6
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