Guanfacine effects on stress, drug craving and prefrontal activation in cocaine dependent individuals: Preliminary findings

Journal of Psychopharmacology

Volumn 26, Issue 7, 2012, Pages 958-972

  Fox, Helen C ^a   Seo, Dongju ^a   Tuit, Keri ^a   Hansen, Julie ^a   Kimmerling, Anne ^a   Morgan, Peter T ^a   Sinha, Rajita ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cocaine abuse; drug craving; drug cue; fMRI; guanfacine; prefrontal activation; stress

Indexed keywords

GUANFACINE; PLACEBO;

ADULT; ANXIETY; AROUSAL; ARTICLE; ASSOCIATION; BRAIN FUNCTION; CLINICAL ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; DRUG EFFECT; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG SAFETY; DRUG TOLERABILITY; FATIGUE; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; GUIDED IMAGERY; HEART DISEASE; HEART OUTPUT; HEART RATE; HELP SEEKING BEHAVIOR; HUMAN; LABORATORY TEST; MALE; PARESTHESIA; PILOT STUDY; PREFRONTAL CORTEX; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STRESS; SYSTOLIC BLOOD PRESSURE; TOBACCO DEPENDENCE; TREATMENT DURATION; VENTROMEDIAL PREFRONTAL CORTEX; WITHDRAWAL SYNDROME;

ADRENERGIC ALPHA-2 RECEPTOR AGONISTS; ADULT; COCAINE-RELATED DISORDERS; COMBINED MODALITY THERAPY; CONNECTICUT; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; GUANFACINE; HUMANS; IMAGERY (PSYCHOTHERAPY); MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEURONS; PILOT PROJECTS; PREFRONTAL CORTEX; STRESS, PSYCHOLOGICAL; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84862876633     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881111430746     Document Type: Article

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