Repeated lofexidine treatment attenuates stress-induced, but not drug cues-induced reinstatement of a heroin-cocaine mixture (speedball) seeking in rats

Neuropsychopharmacology

Volumn 25, Issue 3, 2001, Pages 320-331

  Highfield, D ^a   Yap, J ^a   Grimm, J W ^a   Shalev, U ^a   Shaham, Y ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

Alpha 2 adrenoceptor agonists; Cocaine; Drug self administration; Extinction; Heroin; Reinstatement; Relapse; Stress

Indexed keywords

COCAINE; DIAMORPHINE; LOFEXIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSOCIATION; COCAINE DEPENDENCE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG SELF ADMINISTRATION; DRUG WITHDRAWAL; HEROIN DEPENDENCE; LONG TERM CARE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; RELAPSE; SHOCK; STRESS; WITHDRAWAL SYNDROME;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; BODY WEIGHT; CLONIDINE; COCAINE-RELATED DISORDERS; CONDITIONING, OPERANT; CUES; DRUG COMBINATIONS; ELECTROSHOCK; EXTINCTION, PSYCHOLOGICAL; HEROIN DEPENDENCE; MALE; RATS; RATS, LONG-EVANS; SELF ADMINISTRATION; STRESS, PSYCHOLOGICAL;

EID: 0034887397     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(01)00227-5     Document Type: Article

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