Ligand oligomerization state controls Tie2 receptor trafficking and angiopoietin-2-specific responses

Journal of Cell Science

Volumn 125, Issue 9, 2012, Pages 2212-2223

  Pietilä, Riikka ^a   NäTynki, Marjut ^a   Tammela, Tuomas ^b   Kangas, Jaakko ^a   Pulkki, Kristina H ^b   Limaye, Nisha ^c   Vikkula, Miikka ^c   Koh, Gou Young ^d   Saharinen, Pipsa ^b   Alitalo, Kari ^b   Eklund, Lauri ^a  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c DE DUVE INSTITUTE   (Belgium)

^d Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Angiopoietin; Cell matrix adhesion; Endothelial cell; Tie2; Trafficking

Indexed keywords

ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; BETA1 INTEGRIN; PAXILLIN; PHOSPHOTYROSINE; VERY LATE ACTIVATION ANTIGEN 2; VINCULIN;

ARTICLE; AUTOCRINE EFFECT; CELL ADHESION; CELL MOTILITY; CELL SPREADING; CELL SURFACE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FOCAL ADHESION; HUMAN; HUMAN CELL; MICROTUBULE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

ANGIOPOIETIN-1; ANGIOPOIETIN-2; ANIMALS; CELL ADHESION; CELL MOVEMENT; CELL-MATRIX JUNCTIONS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTEGRIN ALPHA2BETA1; INTRAVITREAL INJECTIONS; MICE; MICROTUBULES; NEOVASCULARIZATION, PHYSIOLOGIC; NIH 3T3 CELLS; PROTEIN MULTIMERIZATION; RECEPTOR PROTEIN-TYROSINE KINASES; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; VITREOUS BODY;

EID: 84862867113     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.098020     Document Type: Article

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