Differential genotoxic effects of subchronic exposure to ethyl tertiary butyl ether in the livers of Aldh2 knockout and wild-type mice

Archives of Toxicology

Volumn 86, Issue 4, 2012, Pages 675-682

  Weng, Zuquan ^a   Suda, Megumi ^a   Ohtani, Katsumi ^a   Mei, Nan ^b   Kawamoto, Toshihiro ^c   Nakajima, Tamie ^d   Wang, Rui Sheng ^a  

^a NATIONAL INSTITUTE OF OCCUPATIONAL SAFETY AND HEALTH   (Japan)

^b NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^d NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Aldh2 knockout mice; ETBE; Genotoxic effect; Liver

Indexed keywords

8 HYDROXYGUANINE; ALDEHYDE DEHYDROGENASE ISOENZYME 2; CARBON MONOXIDE; DNA GLYCOSYLTRANSFERASE; ETHER DERIVATIVE; ETHYL TERTIARY BUTYL ETHER; GASOLINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME DEFICIENCY; ENZYME POLYMORPHISM; FEMALE; GENDER; GENETIC DAMAGE; GENOTOXICITY; HEALTH STATUS; HISTOPATHOLOGY; KNOCKOUT MOUSE; LIVER INJURY; LONG TERM EXPOSURE; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PREDICTION; PRIORITY JOURNAL; SEX DIFFERENCE;

ALDEHYDE DEHYDROGENASE; ANIMALS; CELL ENLARGEMENT; DNA BREAKS; DNA DAMAGE; DNA GLYCOSYLASES; ETHYL ETHERS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HEPATOCYTES; LIVER; LIVER DISEASES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTAGENICITY TESTS; MUTAGENS; SEX FACTORS; SPECIES SPECIFICITY;

MUS;

EID: 84862847002     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0779-x     Document Type: Article

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