메뉴 건너뛰기




Volumn 37, Issue 4, 2007, Pages 287-312

Ethyl tertiary-butyl ether: A toxicological review

Author keywords

Acetaldehyde; ETBE; Ethyl tertiary Butyl Ether; Gasoline Additives; Metabolism; Mutagens; Neurotoxicity; Oxygenates; Reproductive Toxicity; Rodent Carcinogens; Tertiary Butyl Alcohol

Indexed keywords

ACETALDEHYDE; ACETONE; ALCOHOL; CARCINOGEN; ETHER DERIVATIVE; ETHYL TERT BUTYL ETHER; GASOLINE; GLUCURONIDE; MUTAGENIC AGENT; PROPANEDIOL DERIVATIVE; TERT BUTYL ALCOHOL; UNCLASSIFIED DRUG;

EID: 34247536327     PISSN: 10408444     EISSN: 15476898     Source Type: Journal    
DOI: 10.1080/10408440601177723     Document Type: Review
Times cited : (46)

References (128)
  • 1
    • 0021951127 scopus 로고
    • Mouse mitochondrial aldehyde dehydrogenase isozymes: Purification and molecular properties
    • Algar, E.M., and Holmes, R.S. (1985). Mouse mitochondrial aldehyde dehydrogenase isozymes: Purification and molecular properties. Int. J. Biochem. 17:51-60.
    • (1985) Int. J. Biochem , vol.17 , pp. 51-60
    • Algar, E.M.1    Holmes, R.S.2
  • 2
    • 34247511498 scopus 로고    scopus 로고
    • Amato, D.A., and Lagakos, S.W. (1988). Consistency of pathologists' diagnoses in the ED01 experiment. In: Grice, H.C. and Ciminera, J.L. (eds.), Carcinogenicity. The Design, Analysis, and Interpretation of Long-Term Animal Studies. ILSI Monographs. Springer-Verlag, New York. 109-118.
    • Amato, D.A., and Lagakos, S.W. (1988). Consistency of pathologists' diagnoses in the ED01 experiment. In: Grice, H.C. and Ciminera, J.L. (eds.), Carcinogenicity. The Design, Analysis, and Interpretation of Long-Term Animal Studies. ILSI Monographs. Springer-Verlag, New York. 109-118.
  • 3
    • 0033956441 scopus 로고    scopus 로고
    • Biotransformation and kinetics of excretion of ethyl-tert-butyl ether in rats and humans
    • Amberg, A., Rosner, E., and Dekant, W. (2000). Biotransformation and kinetics of excretion of ethyl-tert-butyl ether in rats and humans. Toxicol. Sci. 53:194-201.
    • (2000) Toxicol. Sci , vol.53 , pp. 194-201
    • Amberg, A.1    Rosner, E.2    Dekant, W.3
  • 4
    • 0037255302 scopus 로고    scopus 로고
    • Significance of hepatic preneoplasia in risk identification and early detection of neoplasia
    • Bannasch, P., Haertel, T., and Su, Q. (2003). Significance of hepatic preneoplasia in risk identification and early detection of neoplasia. Toxicol. Pathol. 31:134-139.
    • (2003) Toxicol. Pathol , vol.31 , pp. 134-139
    • Bannasch, P.1    Haertel, T.2    Su, Q.3
  • 5
    • 0023892122 scopus 로고
    • Sites for xenobiotic activation and detoxication within the respiratory tract: Implications for chemically induced toxicity
    • Baron, J., Burke, J.P., Guengerich, F.P., Jakoby, W.B., and Voigt, J.M. (1988). Sites for xenobiotic activation and detoxication within the respiratory tract: Implications for chemically induced toxicity. Toxicol. Appl. Pharmacol. 93:493-505.
    • (1988) Toxicol. Appl. Pharmacol , vol.93 , pp. 493-505
    • Baron, J.1    Burke, J.P.2    Guengerich, F.P.3    Jakoby, W.B.4    Voigt, J.M.5
  • 6
    • 0028824089 scopus 로고
    • Methyl-tertiary- butyl ether (MTBE) - a gasoline additive - causes testicular and lymphohaematopoietic cancers in rats
    • Belpoggi, F., Soffritti, M., and Maltoni, C. (1995). Methyl-tertiary- butyl ether (MTBE) - a gasoline additive - causes testicular and lymphohaematopoietic cancers in rats. Toxicol. Ind. Health 11:119-149.
    • (1995) Toxicol. Ind. Health , vol.11 , pp. 119-149
    • Belpoggi, F.1    Soffritti, M.2    Maltoni, C.3
  • 7
    • 0031587498 scopus 로고    scopus 로고
    • Results of long-term experimental studies on the carcinogenicity of methyl tert-butyl ether
    • Belpoggi, F., Soffritti, M., Filipinni, F., and Maltoni, C. (1997). Results of long-term experimental studies on the carcinogenicity of methyl tert-butyl ether. Ann. N.Y. Acad. Sci. 837:77-95.
    • (1997) Ann. N.Y. Acad. Sci , vol.837 , pp. 77-95
    • Belpoggi, F.1    Soffritti, M.2    Filipinni, F.3    Maltoni, C.4
  • 8
    • 0000265108 scopus 로고    scopus 로고
    • Pathological characterization of testicular tumours and lymphomas-leukaemias, and of their precursors observed in Sprague-Dawley rats exposed to methyltertiary-butyl-ether (MTBE)
    • Belpoggi, F., Soffritti, M., and Maltoni, C. (1998). Pathological characterization of testicular tumours and lymphomas-leukaemias, and of their precursors observed in Sprague-Dawley rats exposed to methyltertiary-butyl-ether (MTBE). Eur. J. Oncol. 3:201-206.
    • (1998) Eur. J. Oncol , vol.3 , pp. 201-206
    • Belpoggi, F.1    Soffritti, M.2    Maltoni, C.3
  • 9
    • 0028810306 scopus 로고
    • Cytochrome P450 2A of nasal epithelium: Regulation and role in carcinogen metabolism
    • Bereziat, J.C., Raffalli, F., Schmezer, P., Frei, E., Geneste, O., and Lang, M.A. (1995). Cytochrome P450 2A of nasal epithelium: Regulation and role in carcinogen metabolism. Mol. Carcinogen. 14:130-139.
    • (1995) Mol. Carcinogen , vol.14 , pp. 130-139
    • Bereziat, J.C.1    Raffalli, F.2    Schmezer, P.3    Frei, E.4    Geneste, O.5    Lang, M.A.6
  • 10
    • 0038485688 scopus 로고    scopus 로고
    • In vivo exposure of female rats to toxicants may affect oocyte quality
    • Berger, T., and Horner, C.M. (2003). In vivo exposure of female rats to toxicants may affect oocyte quality. Reprod. Toxicol. 17:273-281.
    • (2003) Reprod. Toxicol , vol.17 , pp. 273-281
    • Berger, T.1    Horner, C.M.2
  • 13
    • 0021048128 scopus 로고
    • Bioactivation and biotransformation of 1-nitropyrene in liver, lung and nasal tissue of rats
    • Bond, J.A. (1983). Bioactivation and biotransformation of 1-nitropyrene in liver, lung and nasal tissue of rats. Mutat. Res. 124:315-324.
    • (1983) Mutat. Res , vol.124 , pp. 315-324
    • Bond, J.A.1
  • 14
    • 0020511120 scopus 로고
    • Rat nasal tissue activation of benzo(a) pyrene and 2-aminoanthracene to mutagens in Salmonella typhimurium
    • Bond, J.A., and Li, A.P. (1983). Rat nasal tissue activation of benzo(a) pyrene and 2-aminoanthracene to mutagens in Salmonella typhimurium. Environ. Mutagen. 5:311-318.
    • (1983) Environ. Mutagen , vol.5 , pp. 311-318
    • Bond, J.A.1    Li, A.P.2
  • 18
    • 0035040503 scopus 로고    scopus 로고
    • 2u-Globulin nephropathy , renal cell proliferation, and dosimetry of inhaled tert-butyl alcohol in male and female F-344 rats
    • 2u-Globulin nephropathy , renal cell proliferation, and dosimetry of inhaled tert-butyl alcohol in male and female F-344 rats. Toxicol. Sci. 61:176-186.
    • (2001) Toxicol. Sci , vol.61 , pp. 176-186
    • Borghoff, S.J.1    Prescott, J.S.2    Janszen, D.B.3    Wong, B.A.4    Everitt, J.I.5
  • 19
    • 0030661621 scopus 로고    scopus 로고
    • Metabolism-dependent activation and toxicity of chemicals in nasal glands
    • Brittebo, E.B. (1997). Metabolism-dependent activation and toxicity of chemicals in nasal glands. Mutat. Res. 380:61-75.
    • (1997) Mutat. Res , vol.380 , pp. 61-75
    • Brittebo, E.B.1
  • 20
    • 0021240479 scopus 로고
    • Metabolism of nasal carcinogen, phenacetin, in the mucosa of the upper respiratory tract
    • Brittebo, E.B., and Ahlman, M. (1984). Metabolism of nasal carcinogen, phenacetin, in the mucosa of the upper respiratory tract. Chem. Biol. Interact. 50:233-245.
    • (1984) Chem. Biol. Interact , vol.50 , pp. 233-245
    • Brittebo, E.B.1    Ahlman, M.2
  • 23
    • 34247480863 scopus 로고
    • Ethyl tertiary butyl ether: In vitro Chromosome aberrations assay in Chinese Hamster Ovary Cells
    • Bushy Run Research Center, PA, January
    • Bushy Run Research Center. (1995b). Ethyl tertiary butyl ether: In vitro Chromosome aberrations assay in Chinese Hamster Ovary Cells. Unpublished study 94N1425 for ARCO Chemical Company, PA, January 1995.
    • (1995) Unpublished study 94N1425 for ARCO Chemical Company
  • 24
    • 34247468360 scopus 로고
    • Ethyl tertiary butyl ether: Mutagenic potential in the CHO/HGPRT forward mutation assay
    • Bushy Run Research Center, PA, January
    • Bushy Run Research Center. (1995c). Ethyl tertiary butyl ether: Mutagenic potential in the CHO/HGPRT forward mutation assay. Unpublished study 94N1424 for ARCO Chemical Company, PA, January 1995.
    • (1995) Unpublished study 94N1424 for ARCO Chemical Company
  • 25
    • 0019134294 scopus 로고
    • Oxidative demethylation of t-butyl alcohol by rat liver microsomes
    • Cederbaum, A.I., and Cohen, G. (1980). Oxidative demethylation of t-butyl alcohol by rat liver microsomes. Biochem. Biophys. Res. Commun. 97:730-736.
    • (1980) Biochem. Biophys. Res. Commun , vol.97 , pp. 730-736
    • Cederbaum, A.I.1    Cohen, G.2
  • 26
    • 0021049516 scopus 로고
    • Production of formaldehyde and acetone by hydroxyl-radical generating systems during the metabolism of tertiary butyl alcohol
    • Cedarbaum, A.I., Qureshi, A., and Cohen, G. (1980). Production of formaldehyde and acetone by hydroxyl-radical generating systems during the metabolism of tertiary butyl alcohol. Biochem. Pharmacol. 32:3517-3524.
    • (1980) Biochem. Pharmacol , vol.32 , pp. 3517-3524
    • Cedarbaum, A.I.1    Qureshi, A.2    Cohen, G.3
  • 27
    • 34247488274 scopus 로고    scopus 로고
    • Centre International de Toxicologie. (1992a). Ether irritation oculaire aigue chez le lapin, Etude No. 8930 TAL for Total Raffinage Distribution, 26 August 1992.
    • Centre International de Toxicologie. (1992a). Ether irritation oculaire aigue chez le lapin, Etude No. 8930 TAL for Total Raffinage Distribution, 26 August 1992.
  • 28
    • 34247485789 scopus 로고    scopus 로고
    • Centre International de Toxicologie. (1992b). Ether effet irritant aigu sur la peau chez le lapin, Etude No. 8929 TAL for Total Raffinage Distribution, 26 August 1992.
    • Centre International de Toxicologie. (1992b). Ether effet irritant aigu sur la peau chez le lapin, Etude No. 8929 TAL for Total Raffinage Distribution, 26 August 1992.
  • 30
    • 0028876234 scopus 로고
    • Toxicity and carcinogenicity of t-butyl alcohol in rats and mice following chronic exposure in drinking water
    • Cirvello, J.D., Radovsky, A., Heath, J.E., Farnell, D.R., and Lindamood, C. (1995). Toxicity and carcinogenicity of t-butyl alcohol in rats and mice following chronic exposure in drinking water. Toxicol. Ind. Health. 11:151-165.
    • (1995) Toxicol. Ind. Health , vol.11 , pp. 151-165
    • Cirvello, J.D.1    Radovsky, A.2    Heath, J.E.3    Farnell, D.R.4    Lindamood, C.5
  • 31
    • 0035350564 scopus 로고    scopus 로고
    • Dekant, W., Bernauer, U., Rosner, E., and Amberg, A. (2001a). Biotransformation of MTBE, ETBE and TAME after inhalation or ingestion in rats and humans. Health Effects Institute Report No. 102 (May 2001), pp. 29-71.
    • Dekant, W., Bernauer, U., Rosner, E., and Amberg, A. (2001a). Biotransformation of MTBE, ETBE and TAME after inhalation or ingestion in rats and humans. Health Effects Institute Report No. 102 (May 2001), pp. 29-71.
  • 32
    • 0035887112 scopus 로고    scopus 로고
    • Toxicokinetics of ethers used as fuel oxygenates
    • Dekant, W., Bernbauer, U., Rosner, E., and Amberg, A. (2001b). Toxicokinetics of ethers used as fuel oxygenates. Toxicol. Lett. 124:37-45.
    • (2001) Toxicol. Lett , vol.124 , pp. 37-45
    • Dekant, W.1    Bernbauer, U.2    Rosner, E.3    Amberg, A.4
  • 33
    • 0030762718 scopus 로고    scopus 로고
    • Neurotoxicological evaluation of ethyl tertiary-butyl ether following subchronic (90-day) inhalation in the Fischer 344 rat
    • Dorman, D.C., Struve, M.F., Wong, B.A., Morgan, K.T., Janszen, D.B., Gross, E.B., and Bond, J.A. (1997). Neurotoxicological evaluation of ethyl tertiary-butyl ether following subchronic (90-day) inhalation in the Fischer 344 rat. J. Appl. Toxicol. 17:235-242.
    • (1997) J. Appl. Toxicol , vol.17 , pp. 235-242
    • Dorman, D.C.1    Struve, M.F.2    Wong, B.A.3    Morgan, K.T.4    Janszen, D.B.5    Gross, E.B.6    Bond, J.A.7
  • 34
    • 34247508045 scopus 로고    scopus 로고
    • European Union. (2002). European Union Risk Assessment Report 19: Tert-Butyl Methyl Ether. CAS. No. 1634-04-4. EINECS No. 216-653-1. Final Report. Luxembourg: Office for Official Publications of the European Communities.
    • European Union. (2002). European Union Risk Assessment Report Vol. 19: Tert-Butyl Methyl Ether. CAS. No. 1634-04-4. EINECS No. 216-653-1. Final Report. Luxembourg: Office for Official Publications of the European Communities.
  • 36
    • 0033786636 scopus 로고    scopus 로고
    • Controlled human exposure to methyl tertiary butyl ether in gasoline: Symptoms, psychophysiologic and neurobehavioral responses of self-reported sensitive persons
    • Fiedler, N., Kelly-McNeil, K., Mohr, S., Lehrer, P., Opiekun, R.E., Lee, C., Wainman, T., Hamer, R., Weisel, C., Edelberg, R., and Lioy, P.J. (2000). Controlled human exposure to methyl tertiary butyl ether in gasoline: symptoms, psychophysiologic and neurobehavioral responses of self-reported sensitive persons. Environ. Health Perspect. 108:753-763.
    • (2000) Environ. Health Perspect , vol.108 , pp. 753-763
    • Fiedler, N.1    Kelly-McNeil, K.2    Mohr, S.3    Lehrer, P.4    Opiekun, R.E.5    Lee, C.6    Wainman, T.7    Hamer, R.8    Weisel, C.9    Edelberg, R.10    Lioy, P.J.11
  • 37
    • 0018587947 scopus 로고
    • Effects of exposure to acetaldehyde in Syrian hamsters simultaneously treated with benzo(a)pyrene or diethylnitrosamine
    • Feron, V.J. (1979). Effects of exposure to acetaldehyde in Syrian hamsters simultaneously treated with benzo(a)pyrene or diethylnitrosamine. Prog. Exp. Tumor Res. 24:162-176.
    • (1979) Prog. Exp. Tumor Res , vol.24 , pp. 162-176
    • Feron, V.J.1
  • 38
    • 0020070687 scopus 로고
    • Respiratory tract tumours in hamsters exposed to acetaldehyde vapour alone or simultaneously to benzo(a)pyrene or diethylnitrosamine
    • Feron, V.J., Kruysse, A., and Woutersen, R.A. (1982). Respiratory tract tumours in hamsters exposed to acetaldehyde vapour alone or simultaneously to benzo(a)pyrene or diethylnitrosamine. Eur. J. Cancer Clin. Oncol. 18:13-31.
    • (1982) Eur. J. Cancer Clin. Oncol , vol.18 , pp. 13-31
    • Feron, V.J.1    Kruysse, A.2    Woutersen, R.A.3
  • 39
    • 0028140369 scopus 로고
    • Molecular and cellular mechanisms of general anaesthesia
    • Franks, N.P., and Lieb, W.R. (1994). Molecular and cellular mechanisms of general anaesthesia. Nature 367:607-614.
    • (1994) Nature , vol.367 , pp. 607-614
    • Franks, N.P.1    Lieb, W.R.2
  • 40
    • 34247494618 scopus 로고    scopus 로고
    • Gaoua, W. (2003). Ethyl tertiary butyl ether (ETBE), CAS No. 637-92-3: Reproduction/developmental toxicity dose-range finding/probe study by the oral (gavage) route in two strains of rat. CIT Study No. 24168 RSR, unpublished study for Totalfinaelf on behalf of the ETBE Producers' Consortium, 2 October.
    • Gaoua, W. (2003). Ethyl tertiary butyl ether (ETBE), CAS No. 637-92-3: Reproduction/developmental toxicity dose-range finding/probe study by the oral (gavage) route in two strains of rat. CIT Study No. 24168 RSR, unpublished study for Totalfinaelf on behalf of the ETBE Producers' Consortium, 2 October.
  • 41
    • 84866903503 scopus 로고    scopus 로고
    • Ethyl tertiary butyl ether (ETBE): Prenatal developmental toxicity study by the oral route (gavage) in rats
    • RSR, unpublished study for Totalfinaelf on behalf of the ETBE Producers' Consortium
    • Gaoua, W. (2004a). Ethyl tertiary butyl ether (ETBE): Prenatal developmental toxicity study by the oral route (gavage) in rats. CIT Study No. 24860 RSR, unpublished study for Totalfinaelf on behalf of the ETBE Producers' Consortium.
    • (2004) CIT Study , Issue.24860
    • Gaoua, W.1
  • 42
    • 34247523641 scopus 로고    scopus 로고
    • Ethyl tertiary butyl ether (ETBE): Two-generation study (reproduction and fertility effects) by the oral route (gavage) in rats
    • RSR, unpublished study for Totalfinaelf on behalf of the ETBE Producers' Consortium
    • Gaoua, W. (2004b). Ethyl tertiary butyl ether (ETBE): Two-generation study (reproduction and fertility effects) by the oral route (gavage) in rats. CIT Study No. 24859 RSR, unpublished study for Totalfinaelf on behalf of the ETBE Producers' Consortium.
    • (2004) CIT Study , Issue.24859
    • Gaoua, W.1
  • 43
    • 0020539838 scopus 로고
    • Cytochrome P450-dependent monooxygenase activity in nasal membrane of six species
    • Hadley, W.M., and Dahl, A.R. (1983). Cytochrome P450-dependent monooxygenase activity in nasal membrane of six species. Drug Metab. Dispos. 11:275-276.
    • (1983) Drug Metab. Dispos , vol.11 , pp. 275-276
    • Hadley, W.M.1    Dahl, A.R.2
  • 44
    • 1842563805 scopus 로고    scopus 로고
    • A contemporary overview of chronic progressive nephropathy in the laboratory rat, and its significance for human risk assessment
    • Hard, G.C., and Khan K.N. (2004). A contemporary overview of chronic progressive nephropathy in the laboratory rat, and its significance for human risk assessment. Toxicol. Pathol. 32:171-80.
    • (2004) Toxicol. Pathol , vol.32 , pp. 171-180
    • Hard, G.C.1    Khan, K.N.2
  • 47
    • 0025127568 scopus 로고
    • Quantitative and qualitative characteristics of the stages and transitions in the cycle of the rat seminiferous epithelium: Light microscopic observations of perfusion-fixed and plastic-embedded testes
    • Hess, R.A. (1990). Quantitative and qualitative characteristics of the stages and transitions in the cycle of the rat seminiferous epithelium: light microscopic observations of perfusion-fixed and plastic-embedded testes. Biol Reprod. 43:525-542.
    • (1990) Biol Reprod , vol.43 , pp. 525-542
    • Hess, R.A.1
  • 49
    • 0026469366 scopus 로고
    • Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific carcinogen, by rabbit nasal microsomes and cytochrome P450s NMa and NMb
    • Hong, J.-Y., Ding, X., Smith, T.J., Coon, M.J., and Yang, C.S. (1992). Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific carcinogen, by rabbit nasal microsomes and cytochrome P450s NMa and NMb. Carcinogenesis 13:2141-2144.
    • (1992) Carcinogenesis , vol.13 , pp. 2141-2144
    • Hong, J.-Y.1    Ding, X.2    Smith, T.J.3    Coon, M.J.4    Yang, C.S.5
  • 50
    • 0033215097 scopus 로고    scopus 로고
    • Metabolism of methyl tert-butyl ether and other gasoline ethers by human liver microsomes and heterogologously expressed human cytochromes P450: Identification of CYP2A6 as a major catalyst
    • Hong, J.-Y., Wang, Y.-Y., Bondoc, F.Y., Lee, M., Yang, C.S., Hu, W.-Y. and Pan, J. (1999a). Metabolism of methyl tert-butyl ether and other gasoline ethers by human liver microsomes and heterogologously expressed human cytochromes P450: Identification of CYP2A6 as a major catalyst. Toxicol. Appl. Pharmacol. 160:43-48.
    • (1999) Toxicol. Appl. Pharmacol , vol.160 , pp. 43-48
    • Hong, J.-Y.1    Wang, Y.-Y.2    Bondoc, F.Y.3    Lee, M.4    Yang, C.S.5    Hu, W.-Y.6    Pan, J.7
  • 51
    • 0032997612 scopus 로고    scopus 로고
    • Metabolism of methyl tert-butyl ether and other gasoline ethers in mouse liver microsomes lacking cytochrome P450 2E1
    • Hong, J.-Y., Wang, Y.-Y., Bondoc, F.Y., Yang, C.S., Gonzalez, F.J., Pan, Z., Cokonis, C.-D., Hu, W.-Y., and Bao, Z. (1999b). Metabolism of methyl tert-butyl ether and other gasoline ethers in mouse liver microsomes lacking cytochrome P450 2E1. Toxicol. Lett. 105:83-88.
    • (1999) Toxicol. Lett , vol.105 , pp. 83-88
    • Hong, J.-Y.1    Wang, Y.-Y.2    Bondoc, F.Y.3    Yang, C.S.4    Gonzalez, F.J.5    Pan, Z.6    Cokonis, C.-D.7    Hu, W.-Y.8    Bao, Z.9
  • 53
    • 26844447957 scopus 로고    scopus 로고
    • Rat olfactory mucosa displays a high activity in metabolising methyl tert-butyl ether and other gasoline ethers
    • Hong, J.-Y., Wang, Y.-Y., Bondoc, F.Y., Yang, C.S., Lee, M., and Huang, W.-Q. (1997b). Rat olfactory mucosa displays a high activity in metabolising methyl tert-butyl ether and other gasoline ethers. Fund. Appl. Toxicol. 40:205-210.
    • (1997) Fund. Appl. Toxicol , vol.40 , pp. 205-210
    • Hong, J.-Y.1    Wang, Y.-Y.2    Bondoc, F.Y.3    Yang, C.S.4    Lee, M.5    Huang, W.-Q.6
  • 54
    • 0035346408 scopus 로고    scopus 로고
    • Hong, J.-Y., Wang, Y.-Y., Mohr, S.N., Bondoc, F.Y., and Deng, C. (2001). Human cytochrome P-450 isozymes in metabolism and health effects of gasoline ethers. Health Effects Institute Report No. 102 (May 2001), pp. 7-27.
    • Hong, J.-Y., Wang, Y.-Y., Mohr, S.N., Bondoc, F.Y., and Deng, C. (2001). Human cytochrome P-450 isozymes in metabolism and health effects of gasoline ethers. Health Effects Institute Report No. 102 (May 2001), pp. 7-27.
  • 55
    • 35248864098 scopus 로고
    • IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
    • IARC, IARC Press, Lyon, 378 pp
    • IARC. (1988). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 44, Alcohol Drinking, IARC Press, Lyon, 378 pp.
    • (1988) Alcohol Drinking , vol.44
  • 58
    • 34247484836 scopus 로고    scopus 로고
    • IARC. (1999b). Consensus Report. In Species Differences in Thyroid, Kidney and Urinary Bladder Carcinogenesis (C.C. Capen, E. Dybing, J.M.Rice, and J.D. Wilbourn, (Eds.), pp. 5-9. IARC Sci. Pub. No. 147. International Agency for Research on Cancer, Lyon, France.
    • IARC. (1999b). Consensus Report. In Species Differences in Thyroid, Kidney and Urinary Bladder Carcinogenesis (C.C. Capen, E. Dybing, J.M.Rice, and J.D. Wilbourn, (Eds.), pp. 5-9. IARC Sci. Pub. No. 147. International Agency for Research on Cancer, Lyon, France.
  • 59
    • 0032721075 scopus 로고    scopus 로고
    • IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
    • IARC, IARC Press, Lyon, pp
    • IARC. (1999c). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 71, Re-Evaluation of some organic chemicals, hydrazine and hydrogen peroxide (Part Two), IARC Press, Lyon, pp. 319-335.
    • (1999) Re-Evaluation of some organic chemicals, hydrazine and hydrogen peroxide (Part Two) , vol.71 , pp. 319-335
  • 60
    • 34247527254 scopus 로고
    • Acute dermal toxicity study of ethyl-tert-butyl ether (ETBE) in rabbits
    • IIT Research Institute, September
    • IIT Research Institute. (1989a). Acute dermal toxicity study of ethyl-tert-butyl ether (ETBE) in rabbits. Unpublished study L3100 for Amoco Corporation, September.
    • (1989) Unpublished study L3100 for Amoco Corporation
  • 61
    • 34247520047 scopus 로고    scopus 로고
    • IIT Research Institute. (1989b). Acute inhalation toxicity study of ethyl-t-butyl ether (ETBE) in rats. Unpublished Report 1496 for Amoco Corporation, November.
    • IIT Research Institute. (1989b). Acute inhalation toxicity study of ethyl-t-butyl ether (ETBE) in rats. Unpublished Report 1496 for Amoco Corporation, November.
  • 62
    • 33646260133 scopus 로고
    • Respiratory disease in rats
    • Cotchin, E, and Roe, F.J.C, eds, Blackwell Scientific Publications, Oxford and Edinburgh, pp
    • Innes, J.R.M., Garner, F.M., and Stokey, J.L. (1967). Respiratory disease in rats. In: Pathology of Laboratory Rats and Mice, Cotchin, E., and Roe, F.J.C. (eds.), Blackwell Scientific Publications, Oxford and Edinburgh, pp. 229-257.
    • (1967) Pathology of Laboratory Rats and Mice , pp. 229-257
    • Innes, J.R.M.1    Garner, F.M.2    Stokey, J.L.3
  • 63
    • 34247508535 scopus 로고    scopus 로고
    • Institut Pasteur de Lille. (1992a). Etude de toxicité aigue aux doses limites (seion CEE annexe VI J 08-7-92) par voie orale chez le rat: Ether ETBE. Unpublished report IPL-R 920607 for Total Raffinage Distribution, 18 June.
    • Institut Pasteur de Lille. (1992a). Etude de toxicité aigue aux doses limites (seion CEE annexe VI J 08-7-92) par voie orale chez le rat: Ether ETBE. Unpublished report IPL-R 920607 for Total Raffinage Distribution, 18 June.
  • 64
    • 34247513408 scopus 로고    scopus 로고
    • Institut Pasteur de Lille. (1992b). Recherche de mutagenicité sur Salmonella typhimurium His selon la technique de BN Ames. Report IPL-R 920506 for Total Raffinage Distribution, 25 May.
    • Institut Pasteur de Lille. (1992b). Recherche de mutagenicité sur Salmonella typhimurium His selon la technique de BN Ames. Report IPL-R 920506 for Total Raffinage Distribution, 25 May.
  • 65
    • 34247463698 scopus 로고    scopus 로고
    • Institut Pasteur de Lille. (1992c). Etude de l'activité genotoxique par la technique du micronucleus chez la souris sur le produit ether ETBE. Report IPL-R 921009 for Total Raffinage Distribution, 30 October.
    • Institut Pasteur de Lille. (1992c). Etude de l'activité genotoxique par la technique du micronucleus chez la souris sur le produit ether ETBE. Report IPL-R 921009 for Total Raffinage Distribution, 30 October.
  • 66
    • 0029935028 scopus 로고    scopus 로고
    • Possible role of liver cytosolic and mitochondrial aldehyde dehydrogenases in acetaldehyde metabolism
    • Klyosov, A.A., Rashkovetsky, L.G., Tahir, M.K., and Keung, W.-M. (1996). Possible role of liver cytosolic and mitochondrial aldehyde dehydrogenases in acetaldehyde metabolism. Biochemistry 35:4445-4456.
    • (1996) Biochemistry , vol.35 , pp. 4445-4456
    • Klyosov, A.A.1    Rashkovetsky, L.G.2    Tahir, M.K.3    Keung, W.-M.4
  • 67
    • 0033567181 scopus 로고    scopus 로고
    • General anaesthetic actions on ligand-gated ion channels
    • Krasowski, M.D., and Harrison, N. L. (1999). General anaesthetic actions on ligand-gated ion channels. Cell Mol. Life Sci. 10:1278-1303.
    • (1999) Cell Mol. Life Sci , vol.10 , pp. 1278-1303
    • Krasowski, M.D.1    Harrison, N.L.2
  • 68
    • 0021961581 scopus 로고
    • Blood volume in the rat
    • Lee, H.B., and Blaufox, M.D. (1985). Blood volume in the rat. J. Nucl. Med. 26:72-76
    • (1985) J. Nucl. Med , vol.26 , pp. 72-76
    • Lee, H.B.1    Blaufox, M.D.2
  • 69
    • 23044515789 scopus 로고    scopus 로고
    • In situ naphthalene bioactivation and nasal airflow cause region-specific injury patterns in the nasal mucosa of rats exposed to naphthalene by inhalation
    • Lee, M.G., Phimister, A., Morin, D., Buckpitt A., and Plopper, C. (2005). In situ naphthalene bioactivation and nasal airflow cause region-specific injury patterns in the nasal mucosa of rats exposed to naphthalene by inhalation. J. Pharmacol. Exp. Ther. 314:103-110.
    • (2005) J. Pharmacol. Exp. Ther , vol.314 , pp. 103-110
    • Lee, M.G.1    Phimister, A.2    Morin, D.3    Buckpitt, A.4    Plopper, C.5
  • 70
    • 0035887386 scopus 로고    scopus 로고
    • Humancytochrome P450 2A6 is the major enzyme involved in the metabolism of three alkoxyethers used as oxyfuels
    • Le Gal, A., Dreano, Y., Gervasi, P.G., and Berthou, F. (2001). Humancytochrome P450 2A6 is the major enzyme involved in the metabolism of three alkoxyethers used as oxyfuels. Toxicol. Lett. 124:47-58.
    • (2001) Toxicol. Lett , vol.124 , pp. 47-58
    • Le Gal, A.1    Dreano, Y.2    Gervasi, P.G.3    Berthou, F.4
  • 71
    • 0021176420 scopus 로고
    • Hydroxycarboxylic and oxocarboxylic acids in urine: Products from branch-chain amino acid degradation and from ketogenesis
    • Liebach, H.M., and Forst, C. (1984). Hydroxycarboxylic and oxocarboxylic acids in urine: Products from branch-chain amino acid degradation and from ketogenesis. J. Chromatogr. 309:225-242.
    • (1984) J. Chromatogr , vol.309 , pp. 225-242
    • Liebach, H.M.1    Forst, C.2
  • 72
    • 0023939861 scopus 로고
    • Metabolic effects of acetaldehyde
    • Lieber, C.S. (1988). Metabolic effects of acetaldehyde. Biochem.Soc.Trans. 16:241-247.
    • (1988) Biochem.Soc.Trans , vol.16 , pp. 241-247
    • Lieber, C.S.1
  • 73
    • 0022763719 scopus 로고
    • Metabolism of diethylnitrosamine by nasal mucosa and hepatic microsomes from hamster and rat: Species specificity of nasal mucosa
    • Longo, V., Citti, L., and Gervasi, P.G. (1986). Metabolism of diethylnitrosamine by nasal mucosa and hepatic microsomes from hamster and rat: Species specificity of nasal mucosa. Carcinogenesis 7:1323-1328.
    • (1986) Carcinogenesis , vol.7 , pp. 1323-1328
    • Longo, V.1    Citti, L.2    Gervasi, P.G.3
  • 74
    • 0024204558 scopus 로고
    • Biotransformation enzymes in nasal mucosa and liver of Sprague-Dawley rats
    • Longo, V., Citti, L., and Gervasi, P.G. (1988). Biotransformation enzymes in nasal mucosa and liver of Sprague-Dawley rats. Toxicol Lett. 44:289-297.
    • (1988) Toxicol Lett , vol.44 , pp. 289-297
    • Longo, V.1    Citti, L.2    Gervasi, P.G.3
  • 75
    • 0020637185 scopus 로고
    • Assay of blood and tissue aldehydes by HPLC analysis of their 2,4-dinitrophenulhydrazine adducts
    • Lynch, C., Lim, C.K., Thomas, M., and Peters, T.J. (1983). Assay of blood and tissue aldehydes by HPLC analysis of their 2,4-dinitrophenulhydrazine adducts. Clin.Chim. Acta 130:117-122.
    • (1983) Clin.Chim. Acta , vol.130 , pp. 117-122
    • Lynch, C.1    Lim, C.K.2    Thomas, M.3    Peters, T.J.4
  • 76
    • 33646236591 scopus 로고    scopus 로고
    • Methyl tertiary-butyl ether: Studies for potential human health hazards
    • McGregor, D. (2006). Methyl tertiary-butyl ether: Studies for potential human health hazards. Crit. Rev. Toxicol. 36:319-358.
    • (2006) Crit. Rev. Toxicol , vol.36 , pp. 319-358
    • McGregor, D.1
  • 78
    • 0020513574 scopus 로고
    • Metabolism of dimethylamine in the nasal mucosa of the Fischer 344 rat
    • McNulty, M.J., Casanova-Schmitz, M., and Heck, H.D. (1983). Metabolism of dimethylamine in the nasal mucosa of the Fischer 344 rat. Drug Metab. Dispos. 11:421-425.
    • (1983) Drug Metab. Dispos , vol.11 , pp. 421-425
    • McNulty, M.J.1    Casanova-Schmitz, M.2    Heck, H.D.3
  • 79
    • 0001181665 scopus 로고    scopus 로고
    • Comprehensive long-term experimental project of carcinogenicity bioassays on gasoline oxygenated additives: Plan and first report of results from the study on ethyl-tertiary-butyl ether (ETBE)
    • Maltoni, C., Belpoggi, F., Soffritti, M., and Minardi, F. (1999). Comprehensive long-term experimental project of carcinogenicity bioassays on gasoline oxygenated additives: plan and first report of results from the study on ethyl-tertiary-butyl ether (ETBE). Eur. J. Oncol. 4:493-508.
    • (1999) Eur. J. Oncol , vol.4 , pp. 493-508
    • Maltoni, C.1    Belpoggi, F.2    Soffritti, M.3    Minardi, F.4
  • 81
    • 34247549174 scopus 로고
    • Test article: Ethyl tertiary butyl ether; Single dose oral toxicity in rats/LD50 in rats
    • MB Research Laboratories, PA
    • MB Research Laboratories. (1988a). Test article: ethyl tertiary butyl ether; Single dose oral toxicity in rats/LD50 in rats. Unpublished report MB88-9137A for ARCO Chemical Company, PA.
    • (1988) Unpublished report MB88-9137A for ARCO Chemical Company
  • 83
    • 34247531863 scopus 로고
    • MB Research Laboratories, Unpublished study MB, D for ARCO Chemical Company, PA
    • MB Research Laboratories. (1988c). Test substance: Ethyl tertiary butyl ether; eye irritation in rabbits. Unpublished study MB 88-9107 D for ARCO Chemical Company, PA.
    • (1988) Test substance: Ethyl tertiary butyl ether; eye irritation in rabbits , pp. 88-9107
  • 84
    • 34247482272 scopus 로고
    • Test substance ethyl tertiary butyl ether. Primary dermal irritation in rabbits
    • MB Research Laboratories, PA
    • MB Research Laboratories. (1988d). Test substance ethyl tertiary butyl ether. Primary dermal irritation in rabbits. Unpublished report MB 88-9107C for ARCO Chemical Company, PA.
    • (1988) Unpublished report MB 88-9107C for ARCO Chemical Company
  • 85
    • 0032822888 scopus 로고    scopus 로고
    • Effects of a thirteen-week inhalation exposure to ethyl tertiary butyl ether on Fischer-344 rats and CD-1 mice
    • Medinsky, M.A., Wolf, D.C., Cattley, R.C., Wong, B., Janszen, D.B., Farris, G.M., Wright, G.A., and Bond, J.A. (1999). Effects of a thirteen-week inhalation exposure to ethyl tertiary butyl ether on Fischer-344 rats and CD-1 mice. Toxicol. Sci. 51:108-118.
    • (1999) Toxicol. Sci , vol.51 , pp. 108-118
    • Medinsky, M.A.1    Wolf, D.C.2    Cattley, R.C.3    Wong, B.4    Janszen, D.B.5    Farris, G.M.6    Wright, G.A.7    Bond, J.A.8
  • 88
    • 26844520458 scopus 로고    scopus 로고
    • Comparative short-term effects of methyl tertiary butyl ether and unleaded gasoline vapor in female B6C3F1 mice
    • Moser, G.J., Wong, B.A., Wolf, D.C., Moss, O.R., and Goldsworthy, T.L. (1996). Comparative short-term effects of methyl tertiary butyl ether and unleaded gasoline vapor in female B6C3F1 mice. Fundam. Appl. Toxicol. 31:173-183.
    • (1996) Fundam. Appl. Toxicol , vol.31 , pp. 173-183
    • Moser, G.J.1    Wong, B.A.2    Wolf, D.C.3    Moss, O.R.4    Goldsworthy, T.L.5
  • 89
    • 8544279271 scopus 로고    scopus 로고
    • General anesthetic drugs
    • eds. P.L.Munson, R.A. Mueller, and G.R. Breese, pp, Chapman and Hall, New York
    • Mueller, R.A. (1996). General anesthetic drugs. In: Principles of Pharmacology, eds. P.L.Munson, R.A. Mueller, and G.R. Breese, pp. 227-242. Chapman and Hall, New York.
    • (1996) Principles of Pharmacology , pp. 227-242
    • Mueller, R.A.1
  • 90
    • 0344699561 scopus 로고
    • Respiratory infections of rats and mice with emphasis on indigenous mycoplasms
    • Cotchin, E, and Roe, F.J.C, eds, Blackwell Scientific Publications, Oxford and Edinburgh, pp
    • Nelson, J.B. (1967). Respiratory infections of rats and mice with emphasis on indigenous mycoplasms. In: Pathology of Laboratory Rats and Mice, Cotchin, E., and Roe, F.J.C. (eds.), Blackwell Scientific Publications, Oxford and Edinburgh, pp. 259-294.
    • (1967) Pathology of Laboratory Rats and Mice , pp. 259-294
    • Nelson, J.B.1
  • 92
    • 0029609948 scopus 로고
    • Liquid/air partition coefficients of methyl and ethyl t-butyl ethers, t-amyl methyl ether, and t-butyl alcohol
    • Nihlén, A., Löf, A., and Johanson, G. (1995). Liquid/air partition coefficients of methyl and ethyl t-butyl ethers, t-amyl methyl ether, and t-butyl alcohol. J. Exp. Anal. Environ. Epidemiol. 5:573-582.
    • (1995) J. Exp. Anal. Environ. Epidemiol , vol.5 , pp. 573-582
    • Nihlén, A.1    Löf, A.2    Johanson, G.3
  • 93
    • 0032412394 scopus 로고    scopus 로고
    • Controlled ethyl tert-butyl ether (ETBE) exposure of male volunteers (i) Toxicokinetics
    • Nihlén, A., Lof, A., and Johanson, G. (1998a). Controlled ethyl tert-butyl ether (ETBE) exposure of male volunteers (i) Toxicokinetics. Toxicol. Sci. 46:1-10.
    • (1998) Toxicol. Sci , vol.46 , pp. 1-10
    • Nihlén, A.1    Lof, A.2    Johanson, G.3
  • 94
    • 0032429597 scopus 로고    scopus 로고
    • Controlled ethyl tert-butyl ether (ETBE) exposure of male volunteers (ii) Acute effects
    • Nihlén, A., Lof, A., and Johanson, G. (1998b). Controlled ethyl tert-butyl ether (ETBE) exposure of male volunteers (ii) Acute effects. Toxicol. Sci. 46:143-150.
    • (1998) Toxicol. Sci , vol.46 , pp. 143-150
    • Nihlén, A.1    Lof, A.2    Johanson, G.3
  • 95
    • 0032007257 scopus 로고    scopus 로고
    • Experimental exposure to methyl tert-butyl ether: Toxicokinetics in humans
    • Nihlén, A., Lof, A., and Johanson, G. (1998c). Experimental exposure to methyl tert-butyl ether: Toxicokinetics in humans. Toxicol. Appl. Pharmacol. 148:274-280.
    • (1998) Toxicol. Appl. Pharmacol , vol.148 , pp. 274-280
    • Nihlén, A.1    Lof, A.2    Johanson, G.3
  • 96
    • 0345666896 scopus 로고
    • Toxicology and Carcinogenesis Studies of t-Butyl Alcohol in F344/N Rats and B6C3F1 Mice
    • NTP National Toxicology Program, No. 436; NIH Publ. No. 95-3167, Research Triangle Park, NC
    • NTP (National Toxicology Program). (1995). Toxicology and Carcinogenesis Studies of t-Butyl Alcohol in F344/N Rats and B6C3F1 Mice (Tech. Rep. Ser. No. 436; NIH Publ. No. 95-3167), Research Triangle Park, NC.
    • (1995) Tech. Rep. Ser
  • 97
    • 84866932794 scopus 로고
    • Test article: ETBE. Test to evaluate the acute toxicity following a single oral administration (limit test) in the rat
    • No. 76493 for Elf, 17 March
    • Pharmakon Europe. (1994a). Test article: ETBE. Test to evaluate the acute toxicity following a single oral administration (limit test) in the rat. Unpublished report No. 76493 for Elf, 17 March.
    • (1994) Unpublished report
    • Europe, P.1
  • 98
    • 84866888676 scopus 로고
    • Test article: ETBE. Test to evaluate the acute ocular irritation and reversibility in the rabbit (3 animals)
    • Report No. 76293 for Elf, 1 April
    • Pharmakon Europe. (1994b). Test article: ETBE. Test to evaluate the acute ocular irritation and reversibility in the rabbit (3 animals). Report No. 76293 for Elf, 1 April.
    • (1994)
    • Europe, P.1
  • 99
    • 84866888676 scopus 로고
    • Test article: ETBE. Test to evaluate the acute primary cutaneous irritation and corrosivity in the rabbit (3 animals)
    • Report No. 78193 for Elf, 1 April
    • Pharmakon Europe. (1994c). Test article: ETBE. Test to evaluate the acute primary cutaneous irritation and corrosivity in the rabbit (3 animals). Report No. 78193 for Elf, 1 April.
    • (1994)
    • Europe, P.1
  • 100
    • 84866888676 scopus 로고
    • Test article: ETBE. Test to evaluate sensitising potential in the guinea pig
    • Report No. 76393 for Elf, 29 April
    • Pharmakon Europe. (1994d). Test article: ETBE. Test to evaluate sensitising potential in the guinea pig. Report No. 76393 for Elf, 29 April.
    • (1994)
    • Europe, P.1
  • 101
    • 34247544274 scopus 로고    scopus 로고
    • Pharmakon Europe. (1994e). Test article: ETBE. Salmonella typhimurium/mammalian microsome plate incorporation assay (Ames test). Report No. 76593 for Elf, 18 April.
    • Pharmakon Europe. (1994e). Test article: ETBE. Salmonella typhimurium/mammalian microsome plate incorporation assay (Ames test). Report No. 76593 for Elf, 18 April.
  • 102
    • 0031213606 scopus 로고    scopus 로고
    • In vitro uptake of methyl tert-butyl ether in male rat kidney: Use of a two-compartment model to describe protein interactions
    • Poet, T.S., and Borghoff, S.J. (1997). In vitro uptake of methyl tert-butyl ether in male rat kidney: Use of a two-compartment model to describe protein interactions. Toxicol. Appl. Pharmacol. 145:340-348.
    • (1997) Toxicol. Appl. Pharmacol , vol.145 , pp. 340-348
    • Poet, T.S.1    Borghoff, S.J.2
  • 103
    • 0030972416 scopus 로고    scopus 로고
    • Methyl tert-butyl ether causes α2u-globulin nephropathy and enhanced renal cell proliferation in male Fischer-344 rats
    • Prescott-Mathews, J.S., Wolf, D.C., Wong, B.A., and Borghoff, S.J. (1997). Methyl tert-butyl ether causes α2u-globulin nephropathy and enhanced renal cell proliferation in male Fischer-344 rats. Toxicol. Appl. Pharmacol. 143:301-314.
    • (1997) Toxicol. Appl. Pharmacol , vol.143 , pp. 301-314
    • Prescott-Mathews, J.S.1    Wolf, D.C.2    Wong, B.A.3    Borghoff, S.J.4
  • 104
    • 0028293995 scopus 로고
    • Human liver aldehyde dehydrogenases: New method of purification of the major mitochondrial and cytosolic enzymes and re-evaluation of their kinetic properties
    • Rashkovetsky, L.G., Maret, W., and Klyosov, A.A. (1994). Human liver aldehyde dehydrogenases: new method of purification of the major mitochondrial and cytosolic enzymes and re-evaluation of their kinetic properties. Biochim. Biophys. Acta 1205:301-307.
    • (1994) Biochim. Biophys. Acta , vol.1205 , pp. 301-307
    • Rashkovetsky, L.G.1    Maret, W.2    Klyosov, A.A.3
  • 105
    • 34247525910 scopus 로고    scopus 로고
    • Effect of ethyl t-butyl ether (ETBE) on testosterone in male rats
    • Abstract 644
    • Stanard, B., Westover, C., Hirakawa, B., Gonzalez, J., and de Peyster, A. (2003). Effect of ethyl t-butyl ether (ETBE) on testosterone in male rats. Toxicologist 72:S1, Abstract 644.
    • (2003) Toxicologist , vol.72
    • Stanard, B.1    Westover, C.2    Hirakawa, B.3    Gonzalez, J.4    de Peyster, A.5
  • 106
    • 0017282360 scopus 로고
    • Investigations on esophageal carcinogenicity by methylphenylnitrosamine and ethyl alcohol
    • Schmähl, D. (1976). Investigations on esophageal carcinogenicity by methylphenylnitrosamine and ethyl alcohol. Cancer Lett. 1:215-215
    • (1976) Cancer Lett , vol.1 , pp. 215-215
    • Schmähl, D.1
  • 107
    • 1842279550 scopus 로고
    • Experimentelle Untersuchungen zur Syncarcinogenese. 3. Mitteilung: Versuche zur Krebserzeugung bei Ratten bei gleichzeitiger Gabe von Diäthylnitrosamin und Tentrachlorkohlenstoff bzw. Āthylakohol. Zugleich ein experimenteller Beitrag zur Frage der Alkoholzirrhose
    • Schmähl, D., Thomas, C., Sattler, W., and Scheld, G. (1965). Experimentelle Untersuchungen zur Syncarcinogenese. 3. Mitteilung: Versuche zur Krebserzeugung bei Ratten bei gleichzeitiger Gabe von Diäthylnitrosamin und Tentrachlorkohlenstoff bzw. Āthylakohol. Zugleich ein experimenteller Beitrag zur Frage der "Alkoholzirrhose." Z. Krebsforsch. 66:526-532.
    • (1965) Z. Krebsforsch , vol.66 , pp. 526-532
    • Schmähl, D.1    Thomas, C.2    Sattler, W.3    Scheld, G.4
  • 108
    • 0006183450 scopus 로고
    • Methyl tert-butyl ether
    • Elvers, B, Hawkins, S, and Schulz, G, eds, 5th rev. ed, New York, VCH Publishers, pp
    • Scholz, B., Butzert, H., Neumeister, J., and Nierlich, F. (1990). Methyl tert-butyl ether. In: Elvers, B., Hawkins, S., and Schulz, G. (eds.), Ullmann's Encyclopedia of Industrial Chemistry, 5th rev. ed., Vol. A16, New York, VCH Publishers, pp. 543-550.
    • (1990) Ullmann's Encyclopedia of Industrial Chemistry , vol.A16 , pp. 543-550
    • Scholz, B.1    Butzert, H.2    Neumeister, J.3    Nierlich, F.4
  • 110
    • 0036965158 scopus 로고    scopus 로고
    • Results of long-term experimental studies on the carcinogenicity of formaldehyde and acetaldehyde in rats
    • Soffritti, M., Belpoggi, F., Lambertin, L., Lauriola, M., Padovani, M., and Maltoni, C. (2002a). Results of long-term experimental studies on the carcinogenicity of formaldehyde and acetaldehyde in rats. Ann. NY Acad. Sci. 982:87-105.
    • (2002) Ann. NY Acad. Sci , vol.982 , pp. 87-105
    • Soffritti, M.1    Belpoggi, F.2    Lambertin, L.3    Lauriola, M.4    Padovani, M.5    Maltoni, C.6
  • 111
    • 0036965323 scopus 로고    scopus 로고
    • Results of long-term experimental studies on the carcinogenicity of methyl alcohol and ethyl alcohol in rats
    • Soffritti, M., Belpoggi, F., Cevolani, D., Guarino, M., Padovani M., and Maltoni, C. (2002b). Results of long-term experimental studies on the carcinogenicity of methyl alcohol and ethyl alcohol in rats. Ann. NY Acad. Sci. 982:46-69.
    • (2002) Ann. NY Acad. Sci , vol.982 , pp. 46-69
    • Soffritti, M.1    Belpoggi, F.2    Cevolani, D.3    Guarino, M.4    Padovani, M.5    Maltoni, C.6
  • 113
    • 33644771206 scopus 로고    scopus 로고
    • First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats
    • Soffritti, M., Belpoggi, F., Esposti, D.D., Lambertini, L., Tibaldi, E., and Rigano, A. (2006). First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats. Environ. Health Perspect. 114:379-385.
    • (2006) Environ. Health Perspect , vol.114 , pp. 379-385
    • Soffritti, M.1    Belpoggi, F.2    Esposti, D.D.3    Lambertini, L.4    Tibaldi, E.5    Rigano, A.6
  • 116
    • 0015689929 scopus 로고    scopus 로고
    • Swaen, G.J.V., and van Heerde, P. (1973). Tumours of the haematopoietic system. In: Pathology of Tumours in Laboratory Animals, ITumours of the Rat, Part 1, Turusov, V.S. (ed.), International Agency for Research on Cancer, Lyon, pp. 185-201.
    • Swaen, G.J.V., and van Heerde, P. (1973). Tumours of the haematopoietic system. In: Pathology of Tumours in Laboratory Animals, Vol ITumours of the Rat, Part 1, Turusov, V.S. (ed.), International Agency for Research on Cancer, Lyon, pp. 185-201.
  • 117
    • 0031957833 scopus 로고    scopus 로고
    • Oxidation of methyl- and ethyl-tertiary-butyl ethers in rat liver microsomes: Role of the cytochrome P-450 isoforms
    • Turini, A., Amato, G., Longo, V., and Gervasi, P.G. (1998). Oxidation of methyl- and ethyl-tertiary-butyl ethers in rat liver microsomes: role of the cytochrome P-450 isoforms. Arch. Toxicol. 72:207-214.
    • (1998) Arch. Toxicol , vol.72 , pp. 207-214
    • Turini, A.1    Amato, G.2    Longo, V.3    Gervasi, P.G.4
  • 118
    • 33751297587 scopus 로고    scopus 로고
    • Vogel, J. (1997). Measurement of cardiac output in small laboratory animals using recordings of blood conductivity. Am. J. Physiol. 273 (Heart Circ. Physiol. 42):H2520-H2527.
    • Vogel, J. (1997). Measurement of cardiac output in small laboratory animals using recordings of blood conductivity. Am. J. Physiol. 273 (Heart Circ. Physiol. 42):H2520-H2527.
  • 119
    • 0029559745 scopus 로고
    • Health effects of inhaled tertiary amyl methyl ether and ethyl tertiary butyl ether
    • White, R.D., Daughtrey, W.C., and Wells, M.S. (1995). Health effects of inhaled tertiary amyl methyl ether and ethyl tertiary butyl ether. Toxicol. Lett. 82/83:719-724.
    • (1995) Toxicol. Lett , vol.82-83 , pp. 719-724
    • White, R.D.1    Daughtrey, W.C.2    Wells, M.S.3
  • 121
    • 0034899810 scopus 로고    scopus 로고
    • Characterization of tert-butyl alcohol binding to alpha2u-globulin in F-344 rats
    • Williams, T.M., and Borghoff, S.J. (2001). Characterization of tert-butyl alcohol binding to alpha2u-globulin in F-344 rats. Toxicol. Sci. 62:228-235.
    • (2001) Toxicol. Sci , vol.62 , pp. 228-235
    • Williams, T.M.1    Borghoff, S.J.2
  • 125
    • 0027058140 scopus 로고
    • Retinal oxidation activity and biological role of human cytosolic aldehyde dehydrogenase
    • Yoshida A., Hsu, L.C., and Dave V. (1992). Retinal oxidation activity and biological role of human cytosolic aldehyde dehydrogenase. Enzyme 46:239-244.
    • (1992) Enzyme , vol.46 , pp. 239-244
    • Yoshida, A.1    Hsu, L.C.2    Dave, V.3
  • 126
    • 0026503111 scopus 로고
    • Salmonella mutagenicity tests: V. Results from the testing of 311 chemicals
    • Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. (1992). Salmonella mutagenicity tests: V. Results from the testing of 311 chemicals. Environ. Mol. Mutagen. 19(S21):2-141.
    • (1992) Environ. Mol. Mutagen , vol.19 , Issue.S21 , pp. 2-141
    • Zeiger, E.1    Anderson, B.2    Haworth, S.3    Lawlor, T.4    Mortelmans, K.5
  • 127
    • 0033058630 scopus 로고    scopus 로고
    • Biotransformation of coumarin by rodent and human cytochromes P-450: Metabolic basis of tissue-selective toxicity in olfactory mucosa of rats and mice
    • Zhuo, X., Gu, J., Zhang, Q.Y., Spink, D.C., Kaminsky, L.S., and Ding, X. (1999). Biotransformation of coumarin by rodent and human cytochromes P-450: Metabolic basis of tissue-selective toxicity in olfactory mucosa of rats and mice. J Pharmacol. Exp. Ther. 288:463-471.
    • (1999) J Pharmacol. Exp. Ther , vol.288 , pp. 463-471
    • Zhuo, X.1    Gu, J.2    Zhang, Q.Y.3    Spink, D.C.4    Kaminsky, L.S.5    Ding, X.6
  • 128
    • 0025139745 scopus 로고
    • Differences in the kinetic properties and sensitivity to inhibitors of human placental, erythrocyte, and major hepatic aldehyde dehydrogenase isoenzymes
    • Zorzano, A., and Herrera, E. (1990). Differences in the kinetic properties and sensitivity to inhibitors of human placental, erythrocyte, and major hepatic aldehyde dehydrogenase isoenzymes. Biochem. Pharmacol. 39:873-878.
    • (1990) Biochem. Pharmacol , vol.39 , pp. 873-878
    • Zorzano, A.1    Herrera, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.