A conserved polylysine motif in CD86 cytoplasmic tail is necessary for cytoskeletal association and effective co-stimulation

Biochemical and Biophysical Research Communications

Volumn 423, Issue 2, 2012, Pages 301-307

  Girard, Tanya ^a,b   El Far, Mohamed ^b,f,g   Gaucher, Denis ^b   Acuto, Oreste ^c   Beaulé, Geneviève ^b,d   Michel, Frédérique ^c   Mourad, Walid ^b   Sékaly, Rafick Pierre ^a,b,d,e  

^a MCGILL UNIVERSITY   (Canada)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^c INSTITUT PASTEUR   (France)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

^e VGTI Florida   (United States)

^f Boehringer Ingelheim Canada   (Canada)

^g MCGILL UNIVERSITY   (Canada)

Author keywords

APC; CD86; Cytoskeleton; Immunological synapse; T cell

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CD86 ANTIGEN; INTERLEUKIN 2; MUTANT PROTEIN; POLYLYSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CELL STIMULATION; CONJUGATION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOPLASM; CYTOSKELETON; DEPOLARIZATION; HUMAN; HUMAN CELL; IMMUNOLOGICAL SYNAPSE; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN MOTIF; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD86; CONSERVED SEQUENCE; CYTOPLASM; CYTOSKELETON; HUMANS; IMMUNOLOGICAL SYNAPSES; MICE; MOLECULAR SEQUENCE DATA; POLYLYSINE;

MURINAE;

EID: 84862837101     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.05.116     Document Type: Article

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