Subcellular Localization of CD80 Receptors Is Dependent on an Intact Cytoplasmic Tail and Is Required for CD28-Dependent T Cell Costimulation

Journal of Immunology

Volumn 157, Issue 8, 1996, Pages 3270-3279

  Doty, Raymond T ^a   Clark, Edward A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CROSS LINKING REAGENT; LIGAND; PRIMER DNA;

ANIMAL; ARTICLE; CAPPING PHENOMENON; CELL DIVISION; CELL FRACTIONATION; CELL LINE; CELL MEMBRANE; CHEMISTRY; CHO CELL; CYTOLOGY; CYTOPLASM; GENETIC TRANSFECTION; GENETICS; HAMSTER; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; NUCLEOTIDE SEQUENCE; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD28; ANTIGENS, CD80; BASE SEQUENCE; CELL DIVISION; CELL LINE; CELL MEMBRANE; CHO CELLS; CRICETINAE; CROSS-LINKING REAGENTS; CYTOPLASM; DNA PRIMERS; IMMUNOLOGIC CAPPING; LIGANDS; LYMPHOCYTE ACTIVATION; SUBCELLULAR FRACTIONS; T-LYMPHOCYTES; TRANSFECTION;

EID: 0030587897     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Yokochi, T., R. D. Holly, and E. A. Clark. 1982. B lymphoblast antigen (BB-1) expressed on Epstein-Barr virus-activated B cell blasts, B lymphoblastoid cell lines, and Burkitt's lymphomas. J. Immunol. 128:823.
2. Freeman, G. J., A. S. Freedman, J. M. Segil, G. Lee, J. F. Whitman, and L. M. Nadler. 1989. B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J. Immunol. 143:2714.
3. Freedman, A. S., G. J. Freeman, K. Rhynhart, and L. M. Nadler. 1991. Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: a potential mechanism for amplification of T cell activation through the CD28 pathway. Cell. Immunol. 137:429.
4. Young, J. W., L. Koulova, S. A. Soergel, E. A. Clark, R. M. Steinman, and B. Dupont. 1992. The B7/BB1 antigen provides one of several costimulatory signals for the activation of CD4+ T lymphocytes by human blood dendritic cells in vilro. J. Clin. Invest. 90:229.
5. Linsley, P. S., E. A. Clark, and J. A. Ledbetter. 1990. T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1. Proc. Natl. Acad. Sci. USA 87:5031.
6. Linsley, P. S., W. Brady, M. Urnes, L. S. Grosmaire, N. K. Damle, and J. A. Ledbetter. 1991. CTLA-4 is a second receptor for the B cell activation antigen B7. J. Exp. Med. 174:561.
7. Linsley, P. S., and J. A. Ledbetter. 1993. The role of the CD28 receptor during T cell responses to antigen. Annu. Rev. Immunol. 11:191.
8. Tivol, E. A., F. Borriello, A. N. Schweitzer, W. P. Lynch, J. A. Bluestone, and A. H. Sharpe. 1995. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3:541.
9. Waterhouse, P., J. M. Penninger, E. Timms, A. Wakeham, A. Shahinian, K. P. Lee, C. B. Thompson, H. Griesser, and T. W. Mak. 1995. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 270:985.
10. Krummel, M. F., and J. P. Allison. 1995. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 182:459.
11. Walunas, T. L., D. J. Lenschow, C. Y. Bakker, P. S. Linsley, G. J. Freeman, J. M. Green, C. B. Thompson, and J. A. Bluestone. 1994. CTLA-4 can function as a negative regulator of T cell activation. Immunity 1:405.
12. Gribben, J. G., G. J. Freeman, V. A. Boussiotis, P. Rennert, C. L. Jellis, E. Greenfield, M. Barber, V. A. Restivo, Jr., X. Ke, G. S. Gray, and L. M. Nadler. 1995. CTLA4 mediates antigen-specific apoptosis of human T cells. Proc. Natl. Acad. Sci. USA 92:811.
13. Damle, N. K., L. V. Doyle, L. S. Grosmaire, and J. A. Ledbetter. 1988. Differential regulatory signals delivered by antibody binding to the CD28 (Tp44) molecule during the activation of human T lymphocytes. J. Immunol. 140:1753.
14. Azuma, M., D. Ito, H. Yagita, K. Okumura, J. H. Phillips, L. L. Lanier, and C. Somoza. 1993. B70 antigen is a second ligand for CTLA-4 and CD28. Nature 366:76.
15. Freeman, G. J., J. G. Gribben, V. A. Boussiotis, J. W. Ng, V. A. Restivo, Jr., L. A. Lombard, G. S. Gray, and L. M. Nadler. 1993 Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation. Science 262:909.
16. Linsley, P. S., W. Brady, L. Grosmaire, A. Ararfo, N. K. Damle, and J. A. Ledbetltr. 1991. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation. J. Exp. Med. 173:721.
17. Ledbetter, J. A., T. T. Tsu, K. E. Draves, and E. A. Clark. 1985. Differential expression of pan T cell antigens on human T cell subsets. In Perspectives in Immunogenetics and Histocompatibility. E. Heise, ed. American Society of Histocompatibility and Immunogenetics, New York, NY, p. 325.
18. Hansen, J. A., P. J. Martin, P. G. Beatty, E. A. Clark, and J. A. Ledbetter. 1984. Human T lymphocyte cell surface molecules defined by the workshop monoclonal antibodies ("T cell protocol"). In Leukocyte Typing: Human Leukocyte Differentiation Antigens Detected by Monoclonal Antibodies. A. Bernard, A. Boumodl, J. Danoset, C. Milsteon, and S. F. Schlossman, eds. Springer-Verlag, New York, p. 195.
19. Hansen, J. A., P. J. Martin, and R. C. Nowinski. 1980. Monoclonal antibodies identifying a novel T cell antigen and Ia antigens of human lymphocytes. Immunogenetics 10:247.
20. Pilon, M., M. Gullberg, and E. Lundgren. 1991. Transient expression of the CD2 cell surface antigen as a sortable marker to monitor high-frequency transfection of human primary B cells. J Immunol. 146:1047.
21. MacLean-Fletcher, S., and T. D. Pollard. 1980. Mechanism of action of cytochalasin B on actin. Cell 20:329.
22. - memory T lymphocytes. J. Immunol. 143:1761.
23. Schwinzer, R., R. A. Franklin, J. Domenico, H. Renz, and E. W. Gelfand. 1992. Monoclonal antibodies directed to different epitopes in the CD3-TCR complex induce different states of competence in resting human T cells. J. Immunol. 148: 1322.
24. Gillis, S., M. M. Ferm, W. Ou, and K. A. Smith. 1978. T cell growth factor: parameters of production and a quantitative microassay for activity. J. Immunol. 120:2027.
25. Ehlin-Henriksson, B., E. A. Clark, V. Jonsson, and G. Klein. 1983. Studies on the B lymphoblast antigen No. 1 (BB-1) on a series of Burkitt lymphoma lines differing in the expression of the EBV/C3 receptor complex. J. Immunol. 130:2448.
26. Peltz, G. A., M. L. Trounstine, and K. W. Moore. 1988. Cloned and expressed human Fc receptor for IgG mediates anti-CD3-dependent lymphoproliferation. J. Immunol. 141:1891.
27. Tsoukas, C. D., B. Landgraf, J. Bentin, M. Valentine, M. Lotz, J. H. Vaughan, and D. A. Carson. 1985. Activation of resting T lymphocytes by anti-CD3 (T3) antibodies in the absence of monocytes. J. Immunol. 135:1719.
28. Palacios, R. 1985. Mechanism by which accessory cells contribute in growth of resting T lymphocytes initiated by OKT3 antibody. Eur. J. Immunol. 15:645.
29. Wakasugi, H., J. Bertoglio, T. Tursz, and D. Fradelizi. 1985. IL-2 receptor induction on human T lymphocytes: role for IL-2 and monocytes. J. Immunol. 135:321.
30. Simmons, D., M. W. Makgoba, and B. Seed. 1988. ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM. Nature 331: 624.
31. Seed, B., and A. Aruffo. 1987. Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure. Proc. Natl. Acad. Sci. USA 84:3365.
32. Carpén, O., P. Pallai, D. E. Staunton, and T. A. Springer. 1992. Association of intracellular adhesion molecule-1 (ICAM-1) with actin-containing cytoskeleton and anti-actinin. J Cell. Biol. 118:1223.
33. Offringa, R, and B. E. Bierer. 1993. Association of CD2 with tubulin: evidence for a role of the cytoskeleton in T cell activation. J. Biol. Chem. 268:4979.
34. Symington, F. W., W. Brady, and P. S. Linsley. 1993. Expression and function of B7 on human epidermaJ Langerhans cells. J. Immunol. 150:1286.
35. Kupfer, A., and S. J. Singer. 1989. The specific interaction of helper T cells and antigen-presenting B cells. J. Exp. Med. 170:1697.
36. Peach, R. J., J. Bajorath, W. Brady, G. Leytze, J. Greene, J. Naemura, and P. S. Linsley. 1994. Complementary determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1. J. Exp. Med. 180:2049.
37. Peach, R. J., J. Bajorath, J. Naemura, G. Leytze, J. Greene, A. Aruffo, and P. S. Linsley. 1995. Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28. J. Biol. Chem. 270:21181.
38. Fargeas, C. A., A. Truneh, M. Reddy, M. Hurle, R. Sweet, and R.-P. Sékaly. 1995. Identification of residues in the V domain of CD80 (B7-1) implicated in functional interactions with CD28 and CTLA4. J. Exp. Med 182:667.
39. DeLisser, H. M., J. Chilkotowsky, H.-C. Yan, M. L. Daise, C. A. Buck, and S. M. Albelda. 1994. Deletions in the cytoplasmic domain of platelet-endothelial cell adhesion molecule-1 (PECAM-1, CD31) result in changes in ligand binding properties. J. Cell. Biol. 124:195.
40. Ledbetter, J. A., J. B. Imboden, G. L. Schieven, L. S. Grosmaire, P. S. Rabinovitch, T. Lindsten, C. B. Thompson, and C. H. June. 1990. CD28 ligation in T-cell activation: evidence for two signal transduction pathways. Blood 75:1531.
41. Hathcock, K. S., G. Laszlo, H. B. Dickler, J. Bradshaw, P. S. Linsley, and R. J. Hodes. 1993. Identification of an alternative CTLA-4 ligand costimulatory for T cell activation. Science 262:905.
42. Norton, S. D., L. Zuckerman, K. B. Urdahl, R. Shefner, J. Miller, and M. K. Jenkins. 1992. The CD28 ligand, B7, enhances IL-2 production by providing a costimulatory signal to T cells. J. Immunol. 149:1556.
43. Van Seventer, G. A., Y. Shimizu, K. J. Morgan, and S. Shaw. 1990. The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells. J. Immunol. 144:4579.
44. McHugh, R. S., S. N. Ahmed, Y.-C. Wang, K. W. Sell, and P. Selvaraj. 1995. Construction, purification, and functional incorporation on tumor cells of glycolipid-anchored human B7-1 (CD80). Proc. Natl. Acad. Sci. USA 92:8059.
45. Brunschwig, E. B., E. Levine, U. Trefzer, and M. L. Tykocinski. 1995. Glycosylphosphatidylinositol-modified murine B7-1 and B7-2 retain costimulator function. J. Immunol. 155:5498.
46. Zurzolo, C., M. P. Lisanti, I. W. Caras, L. Nitsch, and E. Rodriguez-Boulan. 1993. Glycosylphosphatidylinositol-anchored proteins are preferentially targeted to the basolateral surface in Fischer rat thyroid epithelial cells. J. Cell. Biol. 121:1031.
47. Rosenman, S. J., A. A. Ganji, T. F. Tedder, and W. M. Gallatin. 1993. Syncapping of human T lymphocyte adhesion/activation molecules and their redistribution during interaction with endothelial cells. J. Leukocyte Biol. 53:1.
48. Koulova, L., E. A. Clark, G. Shu, and B. Dupont. 1991. The CD28 ligand B7/ BB1 provides costimulatory signal for alloactivation of CD4+ T cells. J. Exp. Med. 173:759.
49. Ranheim, E. A., and T. J. Kipps. 1993. Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal. J. Exp. Med. 177:925.