Puerarin attenuates endothelial insulin resistance through inhibition of inflammatory response in an IKKβ/IRS-1-dependent manner

Biochimie

Volumn 94, Issue 5, 2012, Pages 1143-1150

  Huang, Fang ^a   Liu, Kang ^a   Du, Hang ^a   Kou, Junping ^a   Liu, Baolin ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Endothelial dysfunction; Inflammation; Insulin resistance; Puerarin

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 6; NITRIC OXIDE; PALMITIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PUERARIN; SERINE; TUMOR NECROSIS FACTOR ALPHA; TYROSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; NONHUMAN; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; VASODILATATION;

ANIMALS; I-KAPPA B KINASE; INFLAMMATION; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; ISOFLAVONES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

PUERARIA MONTANA VAR. LOBATA; RATTUS;

EID: 84862819019     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2012.01.018     Document Type: Article

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