Telmisartan acts through the modulation of ACE-2/ANG 1-7/mas receptor in rats with dilated cardiomyopathy induced by experimental autoimmune myocarditis

Life Sciences

Volumn 90, Issue 7-8, 2012, Pages 289-300

  Sukumaran, Vijayakumar ^a   Veeraveedu, Punniyakoti T ^a,b   Gurusamy, Narasimman ^c   Lakshmanan, Arun Prasath ^a   Yamaguchi, Ken'Ichi ^d   Ma, Meilei ^a   Suzuki, Kenji ^d   Kodama, Makoto ^d   Watanabe, Kenichi ^a  

^a NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

Angiotensin 1 7; Angiotensin converting enzyme 2; Dilated cardiomyopathy; Inflammation; Oxidative stress; Telmisartan

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN[1-7]; ATRIAL NATRIURETIC FACTOR; CD68 ANTIGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CONNECTIVE TISSUE GROWTH FACTOR; G PROTEIN COUPLED RECEPTOR; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; JANUS KINASE; MAS RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; MYOSIN; OSTEOPONTIN; PROTEIN P47; PROTEIN P67; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; TELMISARTAN; TRANSCRIPTION FACTOR GATA 4; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CELL SIZE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DRUG RESPONSE; ENZYME INHIBITION; EXPERIMENTAL AUTOIMMUNE MYOCARDITIS; GENE EXPRESSION REGULATION; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART PROTECTION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; MYOCARDITIS; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BENZIMIDAZOLES; BENZOATES; BLOTTING, WESTERN; CARDIOMYOPATHY, DILATED; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; MALE; MYOCARDITIS; NERVOUS SYSTEM AUTOIMMUNE DISEASE, EXPERIMENTAL; PEPTIDYL-DIPEPTIDASE A; PROTO-ONCOGENE PROTEINS; RATS; RATS, INBRED LEW; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED; SUPEROXIDES;

RATTUS;

EID: 84862817448     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.11.018     Document Type: Article

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