Hsp70 promotes chemoresistance by blocking Bax mitochondrial translocation in ovarian cancer cells

Cancer Letters

Volumn 321, Issue 2, 2012, Pages 137-143

  Yang, Xiaokui ^a   Wang, Jiandong ^a   Zhou, Ying ^a   Wang, Yamei ^b   Wang, Shuyu ^a   Zhang, Weiyuan ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Bax; Cisplatin resistance; Hsp70; Mitochondria; Ovarian cancer

Indexed keywords

CISPLATIN; CYTOCHROME C; HEAT SHOCK PROTEIN 70; MITOCHONDRIAL PROTEIN; PROTEIN BAX; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SERINE PROTEINASE OMI;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER RESISTANCE; CHEMOSENSITIVITY; CONTROLLED STUDY; CYTOSOL; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; MITOCHONDRION; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TRANSPORT;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASES; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CISPLATIN; DRUG RESISTANCE, NEOPLASM; FEMALE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OVARIAN NEOPLASMS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84862810272     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.01.030     Document Type: Article

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