HOCl causes necrotic cell death in human monocyte derived macrophages through calcium dependent calpain activation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1823, Issue 2, 2012, Pages 420-429

  Yang, Ya ting Tina ^a   Whiteman, Matthew ^b   Gieseg, Steven P ^a  

^a UNIVERSITY OF CANTERBURY   (New Zealand)

^b UNIVERSITY OF EXETER   (United Kingdom)

Author keywords

Calcium ion; Calpain; Human monocyte derived macrophage; Hypochlorous acid; Lysosomal stability; Mitochondrial membrane potential

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL T TYPE; CALPAIN; CALPASTATIN; HYPOCHLOROUS ACID; RUTHENIUM RED;

ARTICLE; CELL DEATH; CONCENTRATION (PARAMETERS); CYTOLYSIS; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; HUMAN MONOCYTE DERIVED MACROPHAGE; LYSOSOME; MACROPHAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; MONOCYTE; PRIORITY JOURNAL;

CALCIMYCIN; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM IONOPHORES; CALPAIN; CASPASE 3; CYCLOSPORINE; DANTROLENE; ENZYME INHIBITORS; FLUNARIZINE; HUMANS; HYPOCHLOROUS ACID; LYSOSOMES; MACROPHAGES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MUSCLE RELAXANTS, CENTRAL; NECROSIS; NIFEDIPINE; VERAPAMIL;

EID: 84862809866     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2011.09.019     Document Type: Article

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