Aqueous peroxyl radical exposure to THP-1 cells causes glutathione loss followed by protein oxidation and cell death without increased caspase-3 activity

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1773, Issue 6, 2007, Pages 945-953

  Kappler, Marion ^a   Gerry, Andrew B ^b   Brown, Erin ^a   Reid, Linzi ^a   Leake, David S ^b   Gieseg, Steven P ^a  

^a UNIVERSITY OF CANTERBURY   (New Zealand)

^b UNIVERSITY OF READING   (United Kingdom)

Author keywords

AAPH; Apoptosis; Caspase; Cell death; Glutathione; Macrophage; Protein oxidation; THP 1

Indexed keywords

AZO COMPOUND; BUTHIONINE SULFOXIMINE; CASPASE 3; CYTOCHROME C; FREE RADICAL; GLUTATHIONE; HYDROXYL GROUP; LIPOCORTIN 5; PEROXY RADICAL; PROPIDIUM IODIDE;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOPLASM; DECOMPOSITION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INCUBATION TIME; NECROSIS; OXIDATION; PRIORITY JOURNAL; STAINING; THERMOREGULATION;

AMIDINES; ANNEXIN A5; CASPASE 3; CELL LINE; ENZYME ACTIVATION; GLUTATHIONE; HUMANS; HYDROXYL RADICAL; NECROSIS; OXIDANTS; OXIDATION-REDUCTION; PEROXIDES; TIME FACTORS;

EID: 34249738107     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2007.04.001     Document Type: Article

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