Characterization and evaluation of self-microemulsifying sustained-release pellet formulation of puerarin for oral delivery

International Journal of Pharmaceutics

Volumn 427, Issue 2, 2012, Pages 337-344

  Zhang, Yi ^a   Wang, Ruirui ^a   Wu, Jian ^a,b   Shen, Qi ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Bioavailability; Oral absorption; Puerarin; SMEDDS; Sustained release pellet

Indexed keywords

CASTOR OIL; CREMOPHOR; PROPYLENE GLYCOL; PUERARIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG PELLET; DRUG SOLUBILITY; DRUG STABILITY; EXPERIMENTAL DOG; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTICLE SIZE; PELLET EXTRUSION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM; SPHERONIZATION; SUSTAINED DRUG RELEASE; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION; TRANSMISSION ELECTRON MICROSCOPY;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DELAYED-ACTION PREPARATIONS; DOGS; DRUG STABILITY; EMULSIONS; EXCIPIENTS; INJECTIONS, INTRAVENOUS; ISOFLAVONES; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; PARTICLE SIZE; SOLUBILITY; VASODILATOR AGENTS;

EID: 84862804027     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.02.013     Document Type: Article

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