Controlled drug release from pellets containing water-insoluble drugs dissolved in a self-emulsifying system

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 65, Issue 1, 2007, Pages 94-98

  Serratoni, Mauro ^a   Newton, Michael ^a   Booth, Steven ^b   Clarke, Ashley ^b  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b Merck Sharp & Dohme Limited   (United Kingdom)

Author keywords

Controlled drug release; Film coating; Pellets; Self emulsifying systems; Water insoluble drugs

Indexed keywords

4 HYDROXYBENZOIC ACID ESTER; EMULSIFYING AGENT; ETHYL CELLULOSE; GLYCEROL; LACTOSE; MICROCRYSTALLINE CELLULOSE; POLYSORBATE 80; TALC; WATER;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED DRUG RELEASE; DISSOLUTION; DRUG COATING; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG RELEASE; IN VITRO STUDY; PELLET EXTRUSION; SPHERONIZATION; TABLET FORMULATION; WEIGHT GAIN;

CAPSULES; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DIGLYCERIDES; EMULSIONS; EXCIPIENTS; LACTOSE; METHYLCELLULOSE; MONOGLYCERIDES; PARABENS; PARTICLE SIZE; PHARMACEUTICAL PREPARATIONS; POLYSORBATES; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS; WATER;

EID: 33751518550     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.07.011     Document Type: Article

References (9)

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