Formulation optimization and bioavailability after oral and nasal administration in rabbits of puerarin-loaded microemulsion

Journal of Pharmaceutical Sciences

Volumn 100, Issue 3, 2011, Pages 933-941

  Yu, Aihua ^a   Wang, Haigang ^b   Wang, Jiali ^b   Cao, Fengliang ^a   Gao, Yan ^a   Cui, Jing ^b   Zhai, Guangxi ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Bioavailability; Formulation; Microemulsion; Nasal absorption; Oral absorption; Puerarin

Indexed keywords

ARACHIS OIL; CASTOR OIL; GLYCEROL; LIQUID PARAFFIN; MACROGOL 400; NONOXINOL; OLEIC ACID ETHYL ESTER; POLOXAMER; POLYSORBATE 80; PROPYLENE GLYCOL; PUERARIN;

ANIMAL EXPERIMENT; ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; ELECTRIC CONDUCTIVITY; EXPERIMENTAL RABBIT; MALE; MAXIMUM PLASMA CONCENTRATION; MICROEMULSION; NONHUMAN; PARTICLE SIZE; PH; PROCESS OPTIMIZATION; TIME TO MAXIMUM PLASMA CONCENTRATION; VISCOSITY; ZETA POTENTIAL;

EID: 79251584326     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22333     Document Type: Article

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