-
1
-
-
44449091627
-
A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels.
-
Bouatia-Naji N, Rocheleau G, Van Lommel L, Lemaire K, Schuit F, Cavalcanti-Proença C, Marchand M, Hartikainen AL, Sovio U, De Graeve F, Rung J, Vaxillaire M, Tichet J, Marre M, Balkau B, Weill J, Elliott P, Jarvelin MR, Meyre D, Polychronakos C, Dina C, Sladek R, Froguel P. 2008. A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels. Science 320:1085-1088.
-
(2008)
Science
, vol.320
, pp. 1085-1088
-
-
Bouatia-Naji, N.1
Rocheleau, G.2
Van Lommel, L.3
Lemaire, K.4
Schuit, F.5
Cavalcanti-Proença, C.6
Marchand, M.7
Hartikainen, A.L.8
Sovio, U.9
De Graeve, F.10
Rung, J.11
Vaxillaire, M.12
Tichet, J.13
Marre, M.14
Balkau, B.15
Weill, J.16
Elliott, P.17
Jarvelin, M.R.18
Meyre, D.19
Polychronakos, C.20
Dina, C.21
Sladek, R.22
Froguel, P.23
more..
-
2
-
-
67349188883
-
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits
-
Cho YS, Heo JY, Oh JH, Ban HJ, Yoon D, Lee MH, Kim DJ, Park M, Cha SH, Kim JW, Han BG, Min H, Ahn Y, Park MS, Han HR, Jang HY, Cho EY, Lee JE, Cho NH, Shin C, Park T, Park JW, Lee JK, Cardon L, Clarke G, McCarthy MI, Lee JY, Lee JK, Oh B, Kim HL. 2009. A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat Genet 41:527-534.
-
(2009)
Nat Genet
, vol.41
, pp. 527-534
-
-
Cho, Y.S.1
Heo, J.Y.2
Oh, J.H.3
Ban, H.J.4
Yoon, D.5
Lee, M.H.6
Kim, D.J.7
Park, M.8
Cha, S.H.9
Kim, J.W.10
Han, B.G.11
Min, H.12
Ahn, Y.13
Park, M.S.14
Han, H.R.15
Jang, H.Y.16
Cho, E.Y.17
Lee, J.E.18
Cho, N.H.19
Shin, C.20
Park, T.21
Park, J.W.22
Lee, J.K.23
Cardon, L.24
Clarke, G.25
McCarthy, M.I.26
Lee, J.Y.27
Lee, J.K.28
Oh, B.29
Kim, H.L.30
more..
-
3
-
-
77958517048
-
1C levels and the prevalence of metabolic syndrome in Japanese men: interaction with dietary energy intake
-
1C levels and the prevalence of metabolic syndrome in Japanese men: interaction with dietary energy intake. Am J Epidemiol 172:985-991.
-
(2010)
Am J Epidemiol
, vol.172
, pp. 985-991
-
-
Miyaki, K.1
Oo, T.2
Song, Y.3
Lwin, H.4
Tomita, Y.5
Hoshino, H.6
Suzuk, N.7
Muramatsu, M.8
-
4
-
-
58149151217
-
Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study
-
Paré G, Chasman DI, Parker AN, Nathan DM, Miletich JP, Zee RY, Ridker PM. 2008. Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14, 618 participants in the Women's Genome Health Study. PLoS Genet 4:e1000312.
-
(2008)
PLoS Genet
, vol.4
-
-
Paré, G.1
Chasman, D.I.2
Parker, A.N.3
Nathan, D.M.4
Miletich, J.P.5
Zee, R.Y.6
Ridker, P.M.7
-
5
-
-
33748039452
-
Heritability of cardiovascular and personality traits in 6,148 Sardinians
-
Pilia G, Chen WM, Scuteri A, Orrú M, Albai G, Dei M, Lai S, Usala G, Lai M, Loi P, Mameli C, Vacca L, Deiana M, Olla N, Masala M, Cao A, Najjar SS, Terracciano A, Nedorezov T, Sharov A, Zonderman AB, Abecasis GR, Costa P, Lakatta E, Schlessinger D. 2006. Heritability of cardiovascular and personality traits in 6, 148 Sardinians. PLoS Genet 2:e132.
-
(2006)
PLoS Genet
, vol.2
-
-
Pilia, G.1
Chen, W.M.2
Scuteri, A.3
Orrú, M.4
Albai, G.5
Dei, M.6
Lai, S.7
Usala, G.8
Lai, M.9
Loi, P.10
Mameli, C.11
Vacca, L.12
Deiana, M.13
Olla, N.14
Masala, M.15
Cao, A.16
Najjar, S.S.17
Terracciano, A.18
Nedorezov, T.19
Sharov, A.20
Zonderman, A.B.21
Abecasis, G.R.22
Costa, P.23
Lakatta, E.24
Schlessinger, D.25
more..
-
6
-
-
63249107785
-
Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians
-
Rong R, Hanson RL, Ortiz D, Wiedrich C, Kobes S, Knowler WC, Bogardus C, Baier LJ. 2009. Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians. Diabetes 58:478-488.
-
(2009)
Diabetes
, vol.58
, pp. 478-488
-
-
Rong, R.1
Hanson, R.L.2
Ortiz, D.3
Wiedrich, C.4
Kobes, S.5
Knowler, W.C.6
Bogardus, C.7
Baier, L.J.8
-
7
-
-
79956317360
-
Heterogeneity of genetic associations of CDKAL1 and HHEX with type 2 diabetes mellitus by gender
-
Ryoo H, Woo J, Kim Y, Lee C. 2011. Heterogeneity of genetic associations of CDKAL1 and HHEX with type 2 diabetes mellitus by gender. Eur J Hum Genet 19:672-675.
-
(2011)
Eur J Hum Genet
, vol.19
, pp. 672-675
-
-
Ryoo, H.1
Woo, J.2
Kim, Y.3
Lee, C.4
-
8
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, Chen H, Roix JJ, Kathiresan S, Hirschhorn JN, Daly MJ, Hughes TE, Groop L, Altshuler D, Almgren P, Florez JC, Meyer J, Ardlie K, Bengtsson Boström K, Isomaa B, Lettre G, Lindblad U, Lyon HN, Melander O, Newton-Cheh C, Nilsson P, Orho-Melander M, Råstam L, Speliotes EK, Taskinen MR, Tuomi T, Guiducci C, Berglund A, Carlson J, Gianniny L, Hackett R, Hall L, Holmkvist J, Laurila E, Sjögren M, Sterner M, Surti A, Svensson M, Svensson M, Tewhey R, Blumenstiel B, Parkin M, Defelice M, Barry R, Brodeur W, Camarata J, Chia N, Fava M, Gibbons J, Handsaker B, Healy C, Nguyen K, Gates C, Sougnez C, Gage D, Nizzari M, Gabriel SB, Chirn GW, Ma Q, Parikh H, Richardson D, Ricke D, Purcell S. 2007. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316:1331-1336.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
de Bakker, P.I.5
Chen, H.6
Roix, J.J.7
Kathiresan, S.8
Hirschhorn, J.N.9
Daly, M.J.10
Hughes, T.E.11
Groop, L.12
Altshuler, D.13
Almgren, P.14
Florez, J.C.15
Meyer, J.16
Ardlie, K.17
Bengtsson Boström, K.18
Isomaa, B.19
Lettre, G.20
Lindblad, U.21
Lyon, H.N.22
Melander, O.23
Newton-Cheh, C.24
Nilsson, P.25
Orho-Melander, M.26
Råstam, L.27
Speliotes, E.K.28
Taskinen, M.R.29
Tuomi, T.30
Guiducci, C.31
Berglund, A.32
Carlson, J.33
Gianniny, L.34
Hackett, R.35
Hall, L.36
Holmkvist, J.37
Laurila, E.38
Sjögren, M.39
Sterner, M.40
Surti, A.41
Svensson, M.42
Svensson, M.43
Tewhey, R.44
Blumenstiel, B.45
Parkin, M.46
Defelice, M.47
Barry, R.48
Brodeur, W.49
Camarata, J.50
Chia, N.51
Fava, M.52
Gibbons, J.53
Handsaker, B.54
Healy, C.55
Nguyen, K.56
Gates, C.57
Sougnez, C.58
Gage, D.59
Nizzari, M.60
Gabriel, S.B.61
Chirn, G.W.62
Ma, Q.63
Parikh, H.64
Richardson, D.65
Ricke, D.66
Purcell, S.67
more..
-
9
-
-
78649461131
-
1C levels via glycemic and nonglycemic pathways
-
WTCCC
-
1C levels via glycemic and nonglycemic pathways. Diabetes 59:3229-3239.
-
(2010)
Diabetes
, vol.59
, pp. 3229-3239
-
-
Soranzo, N.1
Sanna, S.2
Wheeler, E.3
Gieger, C.4
Radke, D.5
Dupuis, J.6
Bouatia-Naji, N.7
Langenberg, C.8
Prokopenko, I.9
Stolerman, E.10
Sandhu, M.S.11
Heeney, M.M.12
Devaney, J.M.13
Reilly, M.P.14
Ricketts, S.L.15
Stewart, A.F.16
Voight, B.F.17
Willenborg, C.18
Wright, B.19
Altshuler, D.20
Arking, D.21
Balkau, B.22
Barnes, D.23
Boerwinkle, E.24
Böhm, B.25
Bonnefond, A.26
Bonnycastle, L.L.27
Boomsma, D.I.28
Bornstein, S.R.29
Böttcher, Y.30
Bumpstead, S.31
Burnett-Miller, M.S.32
Campbell, H.33
Cao, A.34
Chambers, J.35
Clark, R.36
Collins, F.S.37
Coresh, J.38
de Geus, E.J.39
Dei, M.40
Deloukas, P.41
Döring, A.42
Egan, J.M.43
Elosua, R.44
Ferrucci, L.45
Forouhi, N.46
Fox, C.S.47
Franklin, C.48
Franzosi, M.G.49
Gallina, S.50
Goel, A.51
Graessler, J.52
Grallert, H.53
Greinacher, A.54
Hadley, D.55
Hall, A.56
Hamsten, A.57
Hayward, C.58
Heath, S.59
Herder, C.60
Homuth, G.61
Hottenga, J.J.62
Hunter-Merrill, R.63
Illig, T.64
Jackson, A.U.65
Jula, A.66
Kleber, M.67
Knouff, C.W.68
Kong, A.69
Kooner, J.70
Köttgen, A.71
Kovacs, P.72
Krohn, K.73
Kühnel, B.74
Kuusisto, J.75
Laakso, M.76
Lathrop, M.77
Lecoeur, C.78
Li, M.79
Li, M.80
Loos, R.J.81
Luan, J.82
Lyssenko, V.83
Mägi, R.84
Magnusson, P.K.85
Mälarstig, A.86
Mangino, M.87
Martínez-Larrad, M.T.88
März, W.89
McArdle, W.L.90
McPherson, R.91
Meisinger, C.92
Meitinger, T.93
Melander, O.94
Mohlke, K.L.95
Mooser, V.E.96
Morken, M.A.97
Narisu, N.98
Nathan, D.M.99
Nauck, M.100
O'Donnell, C.101
Oexle, K.102
Olla, N.103
Pankow, J.S.104
Payne, F.105
Peden, J.F.106
Pedersen, N.L.107
Peltonen, L.108
Perola, M.109
Polasek, O.110
Porcu, E.111
Rader, D.J.112
Rathmann, W.113
Ripatti, S.114
Rocheleau, G.115
Roden, M.116
Rudan, I.117
Salomaa, V.118
Saxena, R.119
Schlessinger, D.120
Schunkert, H.121
Schwarz, P.122
Seedorf, U.123
Selvin, E.124
Serrano-Ríos, M.125
Shrader, P.126
Silveira, A.127
Siscovick, D.128
Song, K.129
Spector, T.D.130
Stefansson, K.131
Steinthorsdottir, V.132
Strachan, D.P.133
Strawbridge, R.134
Stumvoll, M.135
Surakka, I.136
Swift, A.J.137
Tanaka, T.138
Teumer, A.139
Thorleifsson, G.140
Thorsteinsdottir, U.141
Tönjes, A.142
Usala, G.143
Vitart, V.144
Völzke, H.145
Wallaschofski, H.146
Waterworth, D.M.147
Watkins, H.148
Wichmann, H.E.149
Wild, S.H.150
Willemsen, G.151
Williams, G.H.152
Wilson, J.F.153
Winkelmann, J.154
Wright, A.F.155
Zabena, C.156
Zhao, J.H.157
Epstein, S.E.158
Erdmann, J.159
Hakonarson, H.H.160
Kathiresan, S.161
Khaw, K.T.162
Roberts, R.163
Samani, N.J.164
Fleming, M.D.165
Sladek, R.166
Abecasis, G.167
Boehnke, M.168
Froguel, P.169
Groop, L.170
McCarthy, M.I.171
Kao, W.H.172
Florez, J.C.173
Uda, M.174
Wareham, N.J.175
Barroso, I.176
Meigs, J.B.177
more..
-
10
-
-
43249095915
-
Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance
-
EUGENE2 Consortium.
-
Stančáková A, Pihlajamäki J, Kuusisto J, Stefan N, Fritsche A, Häring H, Andreozzi F, Succurro E, Sesti G, Boesgaard TW, Hansen T, Pedersen O, Jansson PA, Hammarstedt A, Smith U, Laakso M, EUGENE2 Consortium. 2008. Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance. J Clin Endocrinol Metab 93:1924-1930.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 1924-1930
-
-
Stančáková, A.1
Pihlajamäki, J.2
Kuusisto, J.3
Stefan, N.4
Fritsche, A.5
Häring, H.6
Andreozzi, F.7
Succurro, E.8
Sesti, G.9
Boesgaard, T.W.10
Hansen, T.11
Pedersen, O.12
Jansson, P.A.13
Hammarstedt, A.14
Smith, U.15
Laakso, M.16
-
11
-
-
34249828965
-
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
-
Steinthorsdottir V, Thorleifsson G, Reynisdottir I, Benediktsson R, Jonsdottir T, Walters GB, Styrkarsdottir U, Gretarsdottir S, Emilsson V, Ghosh S, Baker A, Snorradottir S, Bjarnason H, Ng MC, Hansen T, Bagger Y, Wilensky RL, Reilly MP, Adeyemo A, Chen Y, Zhou J, Gudnason V, Chen G, Huang H, Lashley K, Doumatey A, So WY, Ma RC, Andersen G, Borch-Johnsen K, Jorgensen T, van Vliet-Ostaptchouk JV, Hofker MH, Wijmenga C, Christiansen C, Rader DJ, Rotimi C, Gurney M, Chan JC, Pedersen O, Sigurdsson G, Gulcher JR, Thorsteinsdottir U, Kong A, Stefansson K. 2007. A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 39:770-775.
-
(2007)
Nat Genet
, vol.39
, pp. 770-775
-
-
Steinthorsdottir, V.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Jonsdottir, T.5
Walters, G.B.6
Styrkarsdottir, U.7
Gretarsdottir, S.8
Emilsson, V.9
Ghosh, S.10
Baker, A.11
Snorradottir, S.12
Bjarnason, H.13
Ng, M.C.14
Hansen, T.15
Bagger, Y.16
Wilensky, R.L.17
Reilly, M.P.18
Adeyemo, A.19
Chen, Y.20
Zhou, J.21
Gudnason, V.22
Chen, G.23
Huang, H.24
Lashley, K.25
Doumatey, A.26
So, W.Y.27
Ma, R.C.28
Andersen, G.29
Borch-Johnsen, K.30
Jorgensen, T.31
van Vliet-Ostaptchouk, J.V.32
Hofker, M.H.33
Wijmenga, C.34
Christiansen, C.35
Rader, D.J.36
Rotimi, C.37
Gurney, M.38
Chan, J.C.39
Pedersen, O.40
Sigurdsson, G.41
Gulcher, J.R.42
Thorsteinsdottir, U.43
Kong, A.44
Stefansson, K.45
more..
-
12
-
-
77449089099
-
Glycemic control and complications in type 2 diabetes mellitus
-
Stoler M. 2010. Glycemic control and complications in type 2 diabetes mellitus. Am J Med 123:S3-S11.
-
(2010)
Am J Med
, vol.123
-
-
Stoler, M.1
-
13
-
-
2542461194
-
Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic beta-cells
-
Ubeda M, Kemp DM, Habener JF. 2004. Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic beta-cells. Endocrinology 145:3023-3031.
-
(2004)
Endocrinology
, vol.145
, pp. 3023-3031
-
-
Ubeda, M.1
Kemp, D.M.2
Habener, J.F.3
-
14
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium.
-
Wellcome Trust Case Control Consortium. 2007. Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature 447:661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
15
-
-
56349170898
-
Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population
-
Wu Y, Li H, Loos RJ, Yu Z, Ye X, Chen L, Pan A, Hu FB, Lin X. 2008. Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population. Diabetes 57:2834-2842.
-
(2008)
Diabetes
, vol.57
, pp. 2834-2842
-
-
Wu, Y.1
Li, H.2
Loos, R.J.3
Yu, Z.4
Ye, X.5
Chen, L.6
Pan, A.7
Hu, F.B.8
Lin, X.9
-
16
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
Wellcome Trust Case Control Consortium (WTCCC)
-
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, Lango H, Timpson NJ, Perry JR, Rayner NW, Freathy RM, Barrett JC, Shields B, Morris AP, Ellard S, Groves CJ, Harries LW, Marchini JL, Owen KR, Knight B, Cardon LR, Walker M, Hitman GA, Morris AD, Doney AS, Wellcome Trust Case Control Consortium (WTCCC), McCarthy MI, Hattersley AT. 2007. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316:1336-1341.
-
(2007)
Science
, vol.316
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
Frayling, T.M.4
Elliott, K.S.5
Lango, H.6
Timpson, N.J.7
Perry, J.R.8
Rayner, N.W.9
Freathy, R.M.10
Barrett, J.C.11
Shields, B.12
Morris, A.P.13
Ellard, S.14
Groves, C.J.15
Harries, L.W.16
Marchini, J.L.17
Owen, K.R.18
Knight, B.19
Cardon, L.R.20
Walker, M.21
Hitman, G.A.22
Morris, A.D.23
Doney, A.S.24
McCarthy, M.I.25
Hattersley, A.T.26
more..
|