Sex differences in behavior and expression of cgrp-related genes in a rodent model of chronic migraine

Headache

Volumn 51, Issue 5, 2011, Pages 674-692

  Stucky, Nicholas L ^a   Gregory, Eugene ^a   Winter, Michelle K ^a   He, Yong Yue ^a   Hamilton, Eric S ^a   McCarson, Kenneth E ^a   Berman, Nancy E J ^a,b  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

calcitonin gene related peptide; chronic migraine; facial allodynia; inflammatory soup; locomotor activity; sex difference

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCITONIN LIKE RECEPTOR; CALCITONIN RECEPTOR LIKE RECEPTOR; MESSENGER RNA; RECEPTOR ACTIVITY MODIFYING PROTEIN 1; RECEPTOR COMPONENT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; FEMALE; GENE EXPRESSION; LOCOMOTION; MALE; MEDULLA OBLONGATA; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SEX DIFFERENCE; TRANSFORMED MIGRAINE; TRIGEMINUS GANGLION; UPREGULATION;

ANIMALS; BEHAVIOR, ANIMAL; BRADYKININ; CALCITONIN GENE-RELATED PEPTIDE; CHRONIC DISEASE; DINOPROSTONE; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HISTAMINE; MALE; MIGRAINE DISORDERS; MOTOR ACTIVITY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR ACTIVITY-MODIFYING PROTEIN 1; RECEPTORS, CALCITONIN GENE-RELATED PEPTIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEROTONIN; SEX CHARACTERISTICS;

EID: 79955440776     PISSN: 00178748     EISSN: 15264610     Source Type: Journal    
DOI: 10.1111/j.1526-4610.2011.01882.x     Document Type: Article

References (38)

1. Bigal ME, Lipton RB,. The epidemiology, burden, and comorbidities of migraine. Neurol Clin. 2009; 27: 321-334.
2. Stovner L, Hagen K, Jensen R, et al,. The global burden of headache: A documentation of headache prevalence and disability worldwide. Cephalalgia. 2007; 27: 193-210. (Pubitemid 46354128)
3. Buse DC, Rupnow MF, Lipton RB,. Assessing and managing all aspects of migraine: Migraine attacks, migraine-related functional impairment, common comorbidities, and quality of life. Mayo Clin Proc. 2009; 84: 422-435.
4. Rasmussen BK,. Migraine and tension-type headache in a general population: Precipitating factors, female hormones, sleep pattern and relation to lifestyle. Pain. 1993; 53: 65-72. (Pubitemid 23137269)
5. Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache Disorders: 2nd edition. Cephalalgia. 2004; 24 (Suppl. 1): 9-160.
6. Oshinsky ML, Ginibcgareibsurum S, Luo J,. Recurrent dural stimulation in awake rats chronically reduces periorbital pressure thresholds and potentiates the response to glyceryl trinitrate. Headache. 2007; 47: 741.
7. Liverman CS, Brown JW, Sandhir R, Klein RM, McCarson K, Berman NE,. Oestrogen increases nociception through ERK activation in the trigeminal ganglion: Evidence for a peripheral mechanism of allodynia. Cephalalgia. 2009; 29: 520-531.
8. Steen KH, Reeh PW, Anton F, Handwerker HO,. Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro. J Neurosci. 1992; 12: 86-95.
9. Burstein R, Jakubowski M,. Analgesic triptan action in an animal model of intracranial pain: A race against the development of central sensitization. Ann Neurol. 2004; 55: 27-36. (Pubitemid 38067358)
10. Jakubowski M, Levy D, Kainz V, Zhang XC, Kosaras B, Burstein R,. Sensitization of central trigeminovascular neurons: Blockade by intravenous naproxen infusion. Neuroscience. 2007; 148: 578-583.
11. Zhang XC, Strassman AM, Burstein R, Levy D,. Sensitization and activation of intracranial meningeal nociceptors by mast cell mediators. J Pharmacol Exp Ther. 2007; 322: 806-812. (Pubitemid 47105821)
12. Burstein R, Yamamura H, Malick A, Strassman AM,. Chemical stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain stem trigeminal neurons. J Neurophysiol. 1998; 79: 964-982. (Pubitemid 28095912)
13. Oshinsky ML, Gomonchareonsiri S,. Episodic dural stimulation in awake rats: A model for recurrent headache. Headache. 2007; 47: 1026-1036. (Pubitemid 47057229)
14. Greenspan JD, Craft RM, LeResche L, et al,. Studying sex and gender differences in pain and analgesia: A consensus report. Pain. 2007; 132 (Suppl. 1): S26-S45. (Pubitemid 350026210)
15. McCulloch J, Uddman R, Kingman TA, Edvinsson L,. Calcitonin gene-related peptide: Functional role in cerebrovascular regulation. Proc Natl Acad Sci USA. 1986; 83: 5731-5735. (Pubitemid 16001291)
16. Goadsby PJ, Edvinsson L,. The trigeminovascular system and migraine: Studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats. Ann Neurol. 1993; 33: 48-56. (Pubitemid 23009909)
17. Nakakita K,. Peptidergic innervation in the cerebral blood vessels of the guinea pig: An immunohistochemical study. J Cereb Blood Flow Metab. 1990; 10: 819-826. (Pubitemid 20345223)
18. Keller JT, Marfurt CF,. Peptidergic and serotoninergic innervation of the rat dura mater. J Comp Neurol. 1991; 309: 515-534.
19. Arulmani U, Maassenvandenbrink A, Villalon CM, Saxena PR,. Calcitonin gene-related peptide and its role in migraine pathophysiology. Eur J Pharmacol. 2004; 500: 315-330. (Pubitemid 39304018)
20. Lennerz JK, Ruhle V, Ceppa EP, et al,. Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: Differences between peripheral and central CGRP receptor distribution. J Comp Neurol. 2008; 507: 1277-1299. (Pubitemid 351413572)
21. Liverman CS, Brown JW, Sandhir R, McCarson KE, Berman NE,. Role of the oestrogen receptors GPR30 and ERalpha in peripheral sensitization: Relevance to trigeminal pain disorders in women. Cephalalgia. 2009; 29: 729-741.
22. Fowler SC, Birkestrand BR, Chen R, et al,. A force-plate actometer for quantitating rodent behaviors: Illustrative data on locomotion, rotation, spatial patterning, stereotypies, and tremor. J Neurosci Methods. 2001; 107: 107-124. (Pubitemid 32487615)
23. Pfaffl MW, Horgan GW, Dempfle L,. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res. 2002; 30: e36.
24. Kelman L,. Pain characteristics of the acute migraine attack. Headache. 2006; 46: 942-953. (Pubitemid 43794746)
25. Martins IP, Gouveia RG, Parreira E,. Kinesiophobia in migraine. J Pain. 2006; 7: 445-451. (Pubitemid 43794885)
26. Kessler W, Kirchhoff C, Reeh PW, Handwerker HO,. Excitation of cutaneous afferent nerve endings in vitro by a combination of inflammatory mediators and conditioning effect of substance P. Exp Brain Res. 1992; 91: 467-476.
27. Ter Horst GJ, Meijler WJ, Korf J, Kemper RH,. Trigeminal nociception-induced cerebral Fos expression in the conscious rat. Cephalalgia. 2001; 21: 963-975. (Pubitemid 34626033)
28. Knyihar-Csillik E, Tajti J, Csillik AE, Chadaide Z, Mihaly A, Vecsei L,. Effects of eletriptan on the peptidergic innervation of the cerebral dura mater and trigeminal ganglion, and on the expression of c-fos and c-jun in the trigeminal complex of the rat in an experimental migraine model. Eur J Neurosci. 2000; 12: 3991-4002.
29. Stang PE, Osterhaus JT,. Impact of migraine in the United States: Data from the National Health Interview Survey. Headache. 1993; 33: 29-35. (Pubitemid 23057823)
30. Puri V, Cui L, Liverman CS, et al,. Ovarian steroids regulate neuropeptides in the trigeminal ganglion. Neuropeptides. 2005; 39: 409-417. (Pubitemid 41073622)
31. Flake NM, Bonebreak DB, Gold MS,. Estrogen and inflammation increase the excitability of rat temporomandibular joint afferent neurons. J Neurophysiol. 2005; 93: 1585-1597. (Pubitemid 40283742)
32. Eikermann-Haerter K, Dilekoz E, Kudo C, et al,. Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1. J Clin Invest. 2009; 119: 99-109.
33. Edelmayer RM, Vanderah TW, Majuta L, et al,. Medullary pain facilitating neurons mediate allodynia in headache-related pain. Ann Neurol. 2009; 65: 184-193.
34. Wieseler J, Ellis A, Sprunger D, et al,. A novel method for modeling facial allodynia associated with migraine in awake and freely moving rats. J Neurosci Methods. 2009; 185: 236-245.
35. Burstein R, Cutrer MF, Yarnitsky D,. The development of cutaneous allodynia during a migraine attack clinical evidence for the sequential recruitment of spinal and supraspinal nociceptive neurons in migraine. Brain. 2000; 123 (Pt 8): 1703-1709. (Pubitemid 30481193)
36. Butcher RL, Collins WE, Fugo NW,. Plasma concentration of LH, FSH, prolactin, progesterone and estradiol-17beta throughout the 4-day estrous cycle of the rat. Endocrinology. 1974; 94: 1704-1708.
37. Levy D, Burstein R, Strassman AM,. Calcitonin gene-related peptide does not excite or sensitize meningeal nociceptors: Implications for the pathophysiology of migraine. Ann Neurol. 2005; 58: 698-705. (Pubitemid 41552545)
38. Ottosson A, Edvinsson L,. Release of histamine from dural mast cells by substance P and calcitonin gene-related peptide. Cephalalgia. 1997; 17: 166-174. (Pubitemid 27257341)