Biodegradable copolymers with identical cationic segments and their performance in siRNA delivery

Journal of Controlled Release

Volumn 159, Issue 2, 2012, Pages 251-260

  Qi, Ruogu ^a,b   Liu, Shi ^a,b   Chen, Jie ^a   Xiao, Haihua ^a,b   Yan, Lesan ^a,b   Huang, Yubin ^a   Jing, Xiabin ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Biodegradable cationic copolymers; Click chemistry; Micelle complex; PEGylated polyplexes; siRNA delivery

Indexed keywords

CATIONIC COPOLYMER; CLICK CHEMISTRY; MICELLE-COMPLEX; POLYPLEXES; SIRNA DELIVERY;

AMINO ACIDS; BLOCK COPOLYMERS; COMPLEXATION; DEGRADATION; EFFICIENCY; GENETIC ENGINEERING; LIPOSOMES; LOADING; MOLECULAR BIOLOGY; MOTION PICTURE EXPERTS GROUP STANDARDS; POLYETHYLENE GLYCOLS; RNA;

STRESS ANALYSIS;

CATION; COPOLYMER; HEPARIN; LIPOFECTAMINE; LYSINE; POLYCAPROLACTONE; RIBONUCLEASE; SELF ASSEMBLED MONOLAYER; SMALL INTERFERING RNA; TRIAZOLE;

ARTICLE; BINDING AFFINITY; BIODEGRADABILITY; CLICK CHEMISTRY; COMPLEX FORMATION; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME DEGRADATION; GENE SILENCING; HUMAN; HUMAN CELL; LINKAGE ANALYSIS; MICELLE; PRIORITY JOURNAL; RING OPENING METATHESIS POLYMERIZATION; RNA TRANSPORT;

BIOCOMPATIBLE MATERIALS; CATIONS; CELL LINE, TUMOR; CELL SURVIVAL; CLICK CHEMISTRY; DRUG CARRIERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOCYTOSIS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PARTICLE SIZE; POLYESTERS; POLYLYSINE; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84862791234     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.01.015     Document Type: Article

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