메뉴 건너뛰기




Volumn 31, Issue 2, 2010, Pages 227-236

Microarray analysis reveals the inhibition of nuclear factor-kappa B signaling by aristolochic acid in normal human kidney (HK-2) cells

Author keywords

Aristolochic acid; Confocal microscopy; Human kidney HK 2 cells; Luciferase reporter assay; Microarray analysis; Nuclear factor kappa B

Indexed keywords

ARISTOLOCHIC ACID; COMPLEMENTARY DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; SYNAPTOTAGMIN I;

EID: 76949108679     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2009.197     Document Type: Article
Times cited : (26)

References (44)
  • 1
    • 0000839092 scopus 로고
    • Zur Kenntnis der Aristolochiasäure
    • Rosenmund H, Reichstein T. Zur Kenntnis der Aristolochiasäure. Pharm Acta Helv 1943; 18: 243-61.
    • (1943) Pharm Acta Helv , vol.18 , pp. 243-261
    • Rosenmund, H.1    Reichstein, T.2
  • 2
  • 3
    • 49049104386 scopus 로고    scopus 로고
    • Chemical constituents of Aristolochia constricta: Antispasmodic effects of its constituents in guinea-pig ileum and isolation of a diterpeno-lignan hybrid
    • Zhang G, Shimokawa S, Mochizuki M, Kumamoto T, Nakanishi W, Watanabe T, et al. Chemical constituents of Aristolochia constricta: antispasmodic effects of its constituents in guinea-pig ileum and isolation of a diterpeno-lignan hybrid. J Nat Prod 2008; 71: 1167-72.
    • (2008) J Nat Prod , vol.71 , pp. 1167-1172
    • Zhang, G.1    Shimokawa, S.2    Mochizuki, M.3    Kumamoto, T.4    Nakanishi, W.5    Watanabe, T.6
  • 5
    • 0024987992 scopus 로고
    • Cytotoxic and antimicrobial principles from the roots of Aristolochia longa
    • Hinou J, Demetzos C, Harvala C, Roussakis C. Cytotoxic and antimicrobial principles from the roots of Aristolochia longa. Int J Crude Drug Res 1990; 28: 149-51.
    • (1990) Int J Crude Drug Res , vol.28 , pp. 149-151
    • Hinou, J.1    Demetzos, C.2    Harvala, C.3    Roussakis, C.4
  • 6
    • 0036020624 scopus 로고    scopus 로고
    • Aristolochic acid as a probable human cancer hazard in herbal remedies: A review
    • Arlt VM, Stiborova M, Schmeiser HH. Aristolochic acid as a probable human cancer hazard in herbal remedies: a review. Mutagenesis 2002; 17: 265-77.
    • (2002) Mutagenesis , vol.17 , pp. 265-277
    • Arlt, V.M.1    Stiborova, M.2    Schmeiser, H.H.3
  • 7
    • 0742268907 scopus 로고    scopus 로고
    • H2O2-induced platelet aggregation and increase in intracellular Ca2+ concentration are blocked by inhibitors of intracellular signaling
    • Loiko EN, Samal AB, Shulyakovskaya SM. H2O2-induced platelet aggregation and increase in intracellular Ca2+ concentration are blocked by inhibitors of intracellular signaling. Biochemistry (Mosc) 2003; 68: 1210-6.
    • (2003) Biochemistry (Mosc) , vol.68 , pp. 1210-1216
    • Loiko, E.N.1    Samal, A.B.2    Shulyakovskaya, S.M.3
  • 9
    • 0024391803 scopus 로고
    • Preliminary studies on phospholipase A2-induced mouse paw edema as a model to evaluate antiinflammatory agents
    • Marshall LA, Chang JY, Calhoun W, Yu J, Carlson RP. Preliminary studies on phospholipase A2-induced mouse paw edema as a model to evaluate antiinflammatory agents. J Cell Biochem 1989; 40: 147-55.
    • (1989) J Cell Biochem , vol.40 , pp. 147-155
    • Marshall, L.A.1    Chang, J.Y.2    Calhoun, W.3    Yu, J.4    Carlson, R.P.5
  • 10
    • 0023792292 scopus 로고
    • Edema-inducing activity of phospholipase A2 purified from human synovial fluid and inhibition by aristolochic acid
    • Vishwanath BS, Fawzy AA, Franson RC. Edema-inducing activity of phospholipase A2 purified from human synovial fluid and inhibition by aristolochic acid. Inflammation 1988; 12: 549-61.
    • (1988) Inflammation , vol.12 , pp. 549-561
    • Vishwanath, B.S.1    Fawzy, A.A.2    Franson, R.C.3
  • 11
    • 0027208761 scopus 로고
    • Selective inhibition of group II phospholipase A2 by quercetin
    • Lindahl M, Tagesson C. Selective inhibition of group II phospholipase A2 by quercetin. Inflammation 1993; 17: 573-82.
    • (1993) Inflammation , vol.17 , pp. 573-582
    • Lindahl, M.1    Tagesson, C.2
  • 12
    • 0024493010 scopus 로고
    • Effects of aristolochic acid on phospholipase A2 activity and arachidonate metabolism of human neutrophils
    • Rosenthal MD, Vishwanath BS, Franson RC. Effects of aristolochic acid on phospholipase A2 activity and arachidonate metabolism of human neutrophils. Biochim Biophys Acta 1989; 1001: 1-8.
    • (1989) Biochim Biophys Acta , vol.1001 , pp. 1-8
    • Rosenthal, M.D.1    Vishwanath, B.S.2    Franson, R.C.3
  • 13
    • 0027248443 scopus 로고
    • Effect of aristolochic acid on arachidonic acid cascade and in vivo models of inflammation
    • Moreno JJ. Effect of aristolochic acid on arachidonic acid cascade and in vivo models of inflammation. Immunopharmacology 1993; 26: 1-9.
    • (1993) Immunopharmacology , vol.26 , pp. 1-9
    • Moreno, J.J.1
  • 14
    • 0041336990 scopus 로고    scopus 로고
    • Wound healing studies of Aristolochia bracteolata Lam. with supportive action of antioxidant enzymes
    • Shirwaikar A, Somashekar AP, Udupa AL, Udupa SL, Somashekar S. Wound healing studies of Aristolochia bracteolata Lam. with supportive action of antioxidant enzymes. Phytomedicine 2003; 10: 558-62.
    • (2003) Phytomedicine , vol.10 , pp. 558-562
    • Shirwaikar, A.1    Somashekar, A.P.2    Udupa, A.L.3    Udupa, S.L.4    Somashekar, S.5
  • 15
    • 0020041393 scopus 로고
    • Double blind study of the influence of aristolochic acid on granulocyte phagocytic activity
    • German
    • Kluthe R, Vogt A, Batsford S. Double blind study of the influence of aristolochic acid on granulocyte phagocytic activity. Arzneimittelforschung 1982; 32: 443-5. German.
    • (1982) Arzneimittelforschung , vol.32 , pp. 443-445
    • Kluthe, R.1    Vogt, A.2    Batsford, S.3
  • 16
    • 0027512619 scopus 로고
    • Rapidly progressive interstitial renal fibrosis in young women: Association with slimming regimen including Chinese herbs
    • Vanherweghem JL, Depierreux M, Tielemans C, Abramowicz D, Dratwa M, Jadoul M, et al. Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs. Lancet 1993; 341: 387-91.
    • (1993) Lancet , vol.341 , pp. 387-391
    • Vanherweghem, J.L.1    Depierreux, M.2    Tielemans, C.3    Abramowicz, D.4    Dratwa, M.5    Jadoul, M.6
  • 21
    • 64049117979 scopus 로고    scopus 로고
    • Increased risks of chronic kidney disease associated with prescribed Chinese herbal products suspected to contain aristolochic acid
    • Lai MN, Lai JN, Chen PC, Tseng WL, Chen YY, Hwang JS, et al. Increased risks of chronic kidney disease associated with prescribed Chinese herbal products suspected to contain aristolochic acid. Nephrology 2009; 14: 227-34.
    • (2009) Nephrology , vol.14 , pp. 227-234
    • Lai, M.N.1    Lai, J.N.2    Chen, P.C.3    Tseng, W.L.4    Chen, Y.Y.5    Hwang, J.S.6
  • 22
    • 36248964175 scopus 로고    scopus 로고
    • Microarray analysis of vanillin-regulated gene expression profile in human hepatocarcinoma cells
    • Cheng WY, Hsiang CY, Bau DT, Chen JC, Shen WS, Li CC, et al. Microarray analysis of vanillin-regulated gene expression profile in human hepatocarcinoma cells. Pharmacol Res 2007; 56: 474-82.
    • (2007) Pharmacol Res , vol.56 , pp. 474-482
    • Cheng, W.Y.1    Hsiang, C.Y.2    Bau, D.T.3    Chen, J.C.4    Shen, W.S.5    Li, C.C.6
  • 26
    • 0242490780 scopus 로고    scopus 로고
    • Cytoscape: A software environment for integrated models of biomolecular interaction networks
    • Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 2003; 13: 2498-504.
    • (2003) Genome Res , vol.13 , pp. 2498-2504
    • Shannon, P.1    Markiel, A.2    Ozier, O.3    Baliga, N.S.4    Wang, J.T.5    Ramage, D.6
  • 27
    • 51549086000 scopus 로고    scopus 로고
    • Gene expression profiles modulated by the human carcinogen aristolochic acid i in human cancer cells and their dependence on TP53
    • Simoes ML, Hockley SL, Schwerdtle T, da Costa GG, Schmeiser HH, Phillips DH, et al. Gene expression profiles modulated by the human carcinogen aristolochic acid I in human cancer cells and their dependence on TP53. Toxicol Appl Pharmacol 2008; 232: 86-98.
    • (2008) Toxicol Appl Pharmacol , vol.232 , pp. 86-98
    • Simoes, M.L.1    Hockley, S.L.2    Schwerdtle, T.3    Da Costa, G.G.4    Schmeiser, H.H.5    Phillips, D.H.6
  • 28
    • 33947317378 scopus 로고    scopus 로고
    • Gene expression profiles distinguish the carcinogenic effects of aristolochic acid in target (Kidney) and non-target (Liver) tissues in rats
    • Chen T, Guo L, Zhang L, Shi L, Fang H, Sun Y, et al. Gene expression profiles distinguish the carcinogenic effects of aristolochic acid in target (Kidney) and non-target (Liver) tissues in rats. BMC Bioinformatics 2006; 7: S20.
    • (2006) BMC Bioinformatics , vol.7
    • Chen, T.1    Guo, L.2    Zhang, L.3    Shi, L.4    Fang, H.5    Sun, Y.6
  • 29
    • 34249277438 scopus 로고    scopus 로고
    • Carcinogenspecific gene expression profiles in short-term treated Eker and wildtype rats indicative of pathways involved in renal tumorigenesis
    • Stemmer K, Ellinger-Ziegelbauer H, Ahr HJ, Dietrich DR. Carcinogenspecific gene expression profiles in short-term treated Eker and wildtype rats indicative of pathways involved in renal tumorigenesis. Cancer Res 2007; 67: 4052-68.
    • (2007) Cancer Res , vol.67 , pp. 4052-4068
    • Stemmer, K.1    Ellinger-Ziegelbauer, H.2    Ahr, H.J.3    Dietrich, D.R.4
  • 30
    • 37549055540 scopus 로고    scopus 로고
    • The toxic effects of three Aristolochia compounds on HK-2 cell
    • Chinese
    • Guo YC, Lin ZX, Li H, Luo WH. The toxic effects of three Aristolochia compounds on HK-2 cell. Carcinog Teratog & Mutagen 2006; 18: 88-92. Chinese.
    • (2006) Carcinog Teratog & Mutagen , vol.18 , pp. 88-92
    • Guo, Y.C.1    Lin, Z.X.2    Li, H.3    Luo, W.H.4
  • 31
    • 4544228457 scopus 로고    scopus 로고
    • Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology
    • Beinke S, Ley SC. Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology. Biochem J 2004; 382: 393-409.
    • (2004) Biochem J , vol.382 , pp. 393-409
    • Beinke, S.1    Ley, S.C.2
  • 32
    • 1642457242 scopus 로고    scopus 로고
    • Nuclear receptor signaling in macrophages
    • Valledor AF, Ricote M. Nuclear receptor signaling in macrophages. Biochem Pharmacol 2004; 67: 201-12.
    • (2004) Biochem Pharmacol , vol.67 , pp. 201-212
    • Valledor, A.F.1    Ricote, M.2
  • 33
    • 34250698168 scopus 로고    scopus 로고
    • NF-kappaB, inflammation and pancreatic carcinogenesis: NF-kappaB as a chemoprevention target (review)
    • Zhang Z, Rigas B. NF-kappaB, inflammation and pancreatic carcinogenesis: NF-kappaB as a chemoprevention target (review). Int J Oncol 2006; 29: 185-92.
    • (2006) Int J Oncol , vol.29 , pp. 185-192
    • Zhang, Z.1    Rigas, B.2
  • 34
    • 23244457362 scopus 로고    scopus 로고
    • Inflammation and cancer: When NFkappaB amalgamates the perilous partnership
    • Dobrovolskaia MA, Kozlov SV. Inflammation and cancer: when NFkappaB amalgamates the perilous partnership. Curr Cancer Drug Targets 2005; 5: 325-44.
    • (2005) Curr Cancer Drug Targets , vol.5 , pp. 325-344
    • Dobrovolskaia, M.A.1    Kozlov, S.V.2
  • 35
    • 0037421484 scopus 로고    scopus 로고
    • NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
    • Dajee M, Lazarov M, Zhang JY, Cai T, Green CL, Russell AJ, et al. NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. Nature 2003; 421: 639-43.
    • (2003) Nature , vol.421 , pp. 639-643
    • Dajee, M.1    Lazarov, M.2    Zhang, J.Y.3    Cai, T.4    Green, C.L.5    Russell, A.J.6
  • 36
    • 0033565763 scopus 로고    scopus 로고
    • Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling
    • van Hogerlinden M, Rozell BL, Ahrlund-Richter L, Toftgard R. Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling. Cancer Res 1999; 59: 3299-303.
    • (1999) Cancer Res , vol.59 , pp. 3299-303
    • Van Hogerlinden, M.1    Rozell, B.L.2    Ahrlund-Richter, L.3    Toftgard, R.4
  • 37
    • 0141993068 scopus 로고    scopus 로고
    • CC chemokine ligand 20 partially controls adhesion of naive B cells to activated endothelial cells under shear stress
    • Meissner A, Zilles O, Varona R, Jozefowski K, Ritter U, Marquez G, et al. CC chemokine ligand 20 partially controls adhesion of naive B cells to activated endothelial cells under shear stress. Blood 2003; 102: 2724-7.
    • (2003) Blood , vol.102 , pp. 2724-2727
    • Meissner, A.1    Zilles, O.2    Varona, R.3    Jozefowski, K.4    Ritter, U.5    Marquez, G.6
  • 38
    • 0025601628 scopus 로고
    • Cooperative interaction of nuclear factor-kappa B-and cis-regulatory enhancer binding proteinlike factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines
    • Mukaida N, Mahe Y, Matsushima K. Cooperative interaction of nuclear factor-kappa B-and cis-regulatory enhancer binding proteinlike factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines. J Biol Chem 1990; 265: 21128-33.
    • (1990) J Biol Chem , vol.265 , pp. 21128-21133
    • Mukaida, N.1    Mahe, Y.2    Matsushima, K.3
  • 39
    • 0033761072 scopus 로고    scopus 로고
    • Growth arrest and cell death in the breast tumor cell in response to ionizing radiation and chemotherapeutic agents which induce DNA damage
    • Gewirtz DA. Growth arrest and cell death in the breast tumor cell in response to ionizing radiation and chemotherapeutic agents which induce DNA damage. Breast Cancer Res Treat 2000; 62: 223-35.
    • (2000) Breast Cancer Res Treat , vol.62 , pp. 223-235
    • Gewirtz, D.A.1
  • 40
    • 33646452284 scopus 로고    scopus 로고
    • Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes: Distinct responses to stimuli
    • Deng DX, Spin JM, Tsalenko A, Vailaya A, Ben-Dor A, Yakhini Z, et al. Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes: distinct responses to stimuli. Arterioscler Thromb Vasc Biol 2006; 26: 1058-65.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1058-1065
    • Deng, D.X.1    Spin, J.M.2    Tsalenko, A.3    Vailaya, A.4    Ben-Dor, A.5    Yakhini, Z.6
  • 43
    • 9644302960 scopus 로고    scopus 로고
    • Increased expression of receptor activator of NF-kappaB ligand (RANKL), its receptor RANK and its decoy receptor osteoprotegerin in the colon of Crohn's disease patients
    • Franchimont N, Reenaers C, Lambert C, Belaiche J, Bours V, Malaise M, et al. Increased expression of receptor activator of NF-kappaB ligand (RANKL), its receptor RANK and its decoy receptor osteoprotegerin in the colon of Crohn's disease patients. Clin Exp Immunol 2004; 138: 491-8.
    • (2004) Clin Exp Immunol , vol.138 , pp. 491-498
    • Franchimont, N.1    Reenaers, C.2    Lambert, C.3    Belaiche, J.4    Bours, V.5    Malaise, M.6
  • 44
    • 2642527825 scopus 로고    scopus 로고
    • Receptor for advanced glycation endproduct (RAGE)-mediated nuclear factor-kappaB activation in vasculitic neuropathy
    • Haslbeck KM, Bierhaus A, Erwin S, Kirchner A, Nawroth P, Schlotzer U, et al. Receptor for advanced glycation endproduct (RAGE)-mediated nuclear factor-kappaB activation in vasculitic neuropathy. Muscle Nerve 2004; 29: 853-60.
    • (2004) Muscle Nerve , vol.29 , pp. 853-860
    • Haslbeck, K.M.1    Bierhaus, A.2    Erwin, S.3    Kirchner, A.4    Nawroth, P.5    Schlotzer, U.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.