-
1
-
-
0348047628
-
Gene regulatory factors in pancreatic development
-
Jensen J (2004) Gene regulatory factors in pancreatic development. Dev Dyn 229: 176-200.
-
(2004)
Dev Dyn
, vol.229
, pp. 176-200
-
-
Jensen, J.1
-
2
-
-
0037213587
-
Gene expression cascades in pancreatic development
-
Wilson ME, Scheel D, German MS (2003) Gene expression cascades in pancreatic development. Mech Dev 120: 65-80.
-
(2003)
Mech Dev
, vol.120
, pp. 65-80
-
-
Wilson, M.E.1
Scheel, D.2
German, M.S.3
-
3
-
-
0036730427
-
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
-
Kawaguchi Y, Cooper B, Gannon M, Ray M, MacDonald RJ, Wright CV (2002) The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat Genet 32: 128-134.
-
(2002)
Nat Genet
, vol.32
, pp. 128-134
-
-
Kawaguchi, Y.1
Cooper, B.2
Gannon, M.3
Ray, M.4
MacDonald, R.J.5
Wright, C.V.6
-
4
-
-
34250893048
-
A multipotent progenitor domain guides pancreatic organogenesis
-
Zhou Q, Law AC, Rajagopal J, Anderson WJ, Gray PA, Melton DA (2007) A multipotent progenitor domain guides pancreatic organogenesis. Dev Cell 13: 103-114.
-
(2007)
Dev Cell
, vol.13
, pp. 103-114
-
-
Zhou, Q.1
Law, A.C.2
Rajagopal, J.3
Anderson, W.J.4
Gray, P.A.5
Melton, D.A.6
-
5
-
-
3242784958
-
Neurogenin 3 is a key transcription factor for differentiation of the endocrine pancreas
-
Watada H (2004) Neurogenin 3 is a key transcription factor for differentiation of the endocrine pancreas. Endocr J 51: 255-264.
-
(2004)
Endocr J
, vol.51
, pp. 255-264
-
-
Watada, H.1
-
6
-
-
0034652287
-
Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
-
Gradwohl G, Dierich A, LeMeur M, Guillemot F (2000) Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci USA 97: 1607-1611.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1607-1611
-
-
Gradwohl, G.1
Dierich, A.2
LeMeur, M.3
Guillemot, F.4
-
7
-
-
0033825383
-
Expression of neurogenin3 reveals an islet cell precursor population in the pancreas
-
Schwitzgebel VM, Scheel DW, Conners JR, Kalamaras J, Lee JE, Anderson DJ, Sussel L, Johnson JD, German MS (2000) Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development 127: 3533-3542.
-
(2000)
Development
, vol.127
, pp. 3533-3542
-
-
Schwitzgebel, V.M.1
Scheel, D.W.2
Conners, J.R.3
Kalamaras, J.4
Lee, J.E.5
Anderson, D.J.6
Sussel, L.7
Johnson, J.D.8
German, M.S.9
-
8
-
-
0033606972
-
Notch signalling controls pancreatic cell differentiation
-
Apelqvist A, Li H, Sommer L, Beatus P, Anderson DJ, Honjo T, Hrabe de Angelis M, Lendahl U, Edlund H (1999) Notch signalling controls pancreatic cell differentiation. Nature 400: 877-881.
-
(1999)
Nature
, vol.400
, pp. 877-881
-
-
Apelqvist, A.1
Li, H.2
Sommer, L.3
Beatus, P.4
Anderson, D.J.5
Honjo, T.6
Hrabe de Angelis, M.7
Lendahl, U.8
Edlund, H.9
-
9
-
-
4444235281
-
Proendocrine genes coordinate the pancreatic islet differentiation program in vitro
-
Gasa R, Mrejen C, Leachman N, Otten M, Barnes M, Wang J, Chakrabarti S, Mirmira R, German M (2004) Proendocrine genes coordinate the pancreatic islet differentiation program in vitro. Proc Natl Acad Sci USA 101: 13245-13250.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13245-13250
-
-
Gasa, R.1
Mrejen, C.2
Leachman, N.3
Otten, M.4
Barnes, M.5
Wang, J.6
Chakrabarti, S.7
Mirmira, R.8
German, M.9
-
10
-
-
0037191099
-
-
Heremans Y, Van De Casteele M, in't Veld P, Gradwohl G, Serup P, Madsen O, Pipeleers D, Heimberg H (2002) Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3. J Cell Biol 159: 303-312.
-
Heremans Y, Van De Casteele M, in't Veld P, Gradwohl G, Serup P, Madsen O, Pipeleers D, Heimberg H (2002) Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3. J Cell Biol 159: 303-312.
-
-
-
-
11
-
-
0034524101
-
Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas
-
Sander M, Sussel L, Conners J, Scheel D, Kalamaras J, Dela Cruz F, Schwitzgebel V, Hayes-Jordan A, German M (2000) Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas. Development 127: 5533-5540.
-
(2000)
Development
, vol.127
, pp. 5533-5540
-
-
Sander, M.1
Sussel, L.2
Conners, J.3
Scheel, D.4
Kalamaras, J.5
Dela Cruz, F.6
Schwitzgebel, V.7
Hayes-Jordan, A.8
German, M.9
-
12
-
-
1542297749
-
The MafA transcription factor appears to be responsible for tissue-specific expression of insulin
-
Matsuoka TA, Artner I, Henderson E, Means A, Sander M, Stein R (2004) The MafA transcription factor appears to be responsible for tissue-specific expression of insulin. Proc Natl Acad Sci USA 101: 2930-2933.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2930-2933
-
-
Matsuoka, T.A.1
Artner, I.2
Henderson, E.3
Means, A.4
Sander, M.5
Stein, R.6
-
13
-
-
15944417831
-
PDX-1/ VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance
-
Kaneto H, Nakatani Y, Miyatsuka T, Matsuoka TA, Matsuhisa M, Hori M, Yamasaki Y (2005) PDX-1/ VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance. Diabetes 54: 1009-1022.
-
(2005)
Diabetes
, vol.54
, pp. 1009-1022
-
-
Kaneto, H.1
Nakatani, Y.2
Miyatsuka, T.3
Matsuoka, T.A.4
Matsuhisa, M.5
Hori, M.6
Yamasaki, Y.7
-
14
-
-
0029815929
-
Formation of insulin-producing cells from pancreatic acinar AR42J cells by hepatocyte growth factor
-
Mashima H, Shibata H, Mine T, Kojima I (1996) Formation of insulin-producing cells from pancreatic acinar AR42J cells by hepatocyte growth factor. Endocrinology 137: 3969-3976.
-
(1996)
Endocrinology
, vol.137
, pp. 3969-3976
-
-
Mashima, H.1
Shibata, H.2
Mine, T.3
Kojima, I.4
-
15
-
-
0034640429
-
Beta-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains
-
Mirmira RG, Watada H, German MS (2000) Beta-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains. J Biol Chem 275: 14743-14751.
-
(2000)
J Biol Chem
, vol.275
, pp. 14743-14751
-
-
Mirmira, R.G.1
Watada, H.2
German, M.S.3
-
16
-
-
33845947091
-
Amelioration of glucose tolerance by hepatic inhibition of nuclear factor kappaB in db/db mice
-
Tamura Y, Ogihara T, Uchida T, Ikeda F, Kumashiro N, Nomiyama T, Sato F, Hirose T, Tanaka Y, Mochizuki H, Kawamori R, Watada H. Amelioration of glucose tolerance by hepatic inhibition of nuclear factor kappaB in db/db mice. Diabetologia 50: 131-141.
-
Diabetologia
, vol.50
, pp. 131-141
-
-
Tamura, Y.1
Ogihara, T.2
Uchida, T.3
Ikeda, F.4
Kumashiro, N.5
Nomiyama, T.6
Sato, F.7
Hirose, T.8
Tanaka, Y.9
Mochizuki, H.10
Kawamori, R.11
Watada, H.12
-
17
-
-
0029864906
-
Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells
-
Mashima H, Ohnishi H, Wakabayashi K, Mine T, Miyagawa J, Hanafusa T, Seno M, Yamada H, Kojima I (1996) Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells. J Clin Invest 97: 1647-1654.
-
(1996)
J Clin Invest
, vol.97
, pp. 1647-1654
-
-
Mashima, H.1
Ohnishi, H.2
Wakabayashi, K.3
Mine, T.4
Miyagawa, J.5
Hanafusa, T.6
Seno, M.7
Yamada, H.8
Kojima, I.9
-
18
-
-
0035129123
-
Changes in the expression of transcription factors in pancreatic AR42J cells during differentiation into insulin-produc ing cells
-
Zhang YQ, Mashima H, Kojima I (2001) Changes in the expression of transcription factors in pancreatic AR42J cells during differentiation into insulin-produc ing cells. Diabetes 50 (Suppl 1): S10-14.
-
(2001)
Diabetes
, vol.50
, Issue.SUPPL. 1
-
-
Zhang, Y.Q.1
Mashima, H.2
Kojima, I.3
-
19
-
-
0034713767
-
Transcription factor expression and hormone production in pancreatic AR42J cells
-
Palgi J, Stumpf E, Otonkoski T (2000) Transcription factor expression and hormone production in pancreatic AR42J cells. Mol Cell Endocrinol 165: 41-49.
-
(2000)
Mol Cell Endocrinol
, vol.165
, pp. 41-49
-
-
Palgi, J.1
Stumpf, E.2
Otonkoski, T.3
-
20
-
-
33646157740
-
Activin A-induced expression of PAX4 in AR42J-B13 cells involves the increase in transactivation of E47/ E12
-
Kanno R, Ogihara T, Igarashi Y, Tanaka Y, Smith SB, Kojima I, German MS, Kawamori R, Watada H (2006) Activin A-induced expression of PAX4 in AR42J-B13 cells involves the increase in transactivation of E47/ E12. Biochim Biophys Acta 1759: 44-50.
-
(2006)
Biochim Biophys Acta
, vol.1759
, pp. 44-50
-
-
Kanno, R.1
Ogihara, T.2
Igarashi, Y.3
Tanaka, Y.4
Smith, S.B.5
Kojima, I.6
German, M.S.7
Kawamori, R.8
Watada, H.9
-
21
-
-
25844456544
-
Genetic determinants of pancreatic epsilon-cell development
-
Heller RS, Jenny M, Collombat P, Mansouri A, Tomasetto C, Madsen OD, Mellitzer G, Gradwohl G, Serup P (2005) Genetic determinants of pancreatic epsilon-cell development. Dev Biol 286: 217-224.
-
(2005)
Dev Biol
, vol.286
, pp. 217-224
-
-
Heller, R.S.1
Jenny, M.2
Collombat, P.3
Mansouri, A.4
Tomasetto, C.5
Madsen, O.D.6
Mellitzer, G.7
Gradwohl, G.8
Serup, P.9
-
22
-
-
1542267814
-
Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development
-
Prado CL, Pugh-Bernard AE, Elghazi L, Sosa-Pineda B, Sussel L (2004) Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development. Proc Natl Acad Sci USA 101: 2924-2929.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2924-2929
-
-
Prado, C.L.1
Pugh-Bernard, A.E.2
Elghazi, L.3
Sosa-Pineda, B.4
Sussel, L.5
-
23
-
-
0141643340
-
Neurogenin3 and hepatic nuclear factor 1 cooperate in activating pancreatic expression of Pax4
-
Smith SB, Gasa R, Watada H, Wang J, Griffen SC, German MS (2003) Neurogenin3 and hepatic nuclear factor 1 cooperate in activating pancreatic expression of Pax4. J Biol Chem 278: 38254-38259.
-
(2003)
J Biol Chem
, vol.278
, pp. 38254-38259
-
-
Smith, S.B.1
Gasa, R.2
Watada, H.3
Wang, J.4
Griffen, S.C.5
German, M.S.6
-
24
-
-
0037931806
-
Distinct gene expression programs function in progenitor and mature islet cells
-
Watada H, Scheel DW, Leung J, German MS (2003) Distinct gene expression programs function in progenitor and mature islet cells. J Biol Chem 278: 17130-17140.
-
(2003)
J Biol Chem
, vol.278
, pp. 17130-17140
-
-
Watada, H.1
Scheel, D.W.2
Leung, J.3
German, M.S.4
-
25
-
-
2442666735
-
Transcriptional networks controlling pancreatic development and beta cell function
-
Servitja JM, Ferrer J (2004) Transcriptional networks controlling pancreatic development and beta cell function. Diabetologia 47: 597-613.
-
(2004)
Diabetologia
, vol.47
, pp. 597-613
-
-
Servitja, J.M.1
Ferrer, J.2
-
26
-
-
0032417268
-
The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas
-
Krapp A, Knofler M, Ledermann B, Burki K, Berney C, Zoerkler N, Hagenbuchle O, Wellauer PK (1998) The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes Dev 12: 3752-3763.
-
(1998)
Genes Dev
, vol.12
, pp. 3752-3763
-
-
Krapp, A.1
Knofler, M.2
Ledermann, B.3
Burki, K.4
Berney, C.5
Zoerkler, N.6
Hagenbuchle, O.7
Wellauer, P.K.8
-
27
-
-
0041970072
-
Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells
-
Matsuoka TA, Zhao L, Artner I, Jarrett HW, Friedman D, Means A, Stein R (2003) Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells. Mol Cell Biol 23: 6049-6062.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 6049-6062
-
-
Matsuoka, T.A.1
Zhao, L.2
Artner, I.3
Jarrett, H.W.4
Friedman, D.5
Means, A.6
Stein, R.7
-
28
-
-
0142091542
-
Opposing actions of Arx and Pax4 in endocrine pancreas development
-
Collombat P, Mansouri A, Hecksher-Sorensen J, Serup P, Krull J, Gradwohl G, Gruss P (2003) Opposing actions of Arx and Pax4 in endocrine pancreas development. Genes Dev 17: 2591-2603.
-
(2003)
Genes Dev
, vol.17
, pp. 2591-2603
-
-
Collombat, P.1
Mansouri, A.2
Hecksher-Sorensen, J.3
Serup, P.4
Krull, J.5
Gradwohl, G.6
Gruss, P.7
-
29
-
-
0030897629
-
The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas
-
Sosa-Pineda B, Chowdhury K, Torres M, Oliver G, Gruss P (1997) The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature 386: 399-402.
-
(1997)
Nature
, vol.386
, pp. 399-402
-
-
Sosa-Pineda, B.1
Chowdhury, K.2
Torres, M.3
Oliver, G.4
Gruss, P.5
-
30
-
-
2542484345
-
The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: Evidence for feedback activation of the nkx6.1 gene by Nkx6.1
-
Iype T, Taylor DG, Ziesmann SM, Garmey JC, Watada H, Mirmira RG (2004) The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1. Mol Endocrinol 18: 1363-1375.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 1363-1375
-
-
Iype, T.1
Taylor, D.G.2
Ziesmann, S.M.3
Garmey, J.C.4
Watada, H.5
Mirmira, R.G.6
-
31
-
-
23944494573
-
The C-terminal domain of the beta cell homeodomain factor Nkx6.1 enhances sequence-selective DNA binding at the insulin promoter
-
Taylor DG, Babu D, Mirmira RG (2005) The C-terminal domain of the beta cell homeodomain factor Nkx6.1 enhances sequence-selective DNA binding at the insulin promoter. Biochemistry 44: 11269-11278.
-
(2005)
Biochemistry
, vol.44
, pp. 11269-11278
-
-
Taylor, D.G.1
Babu, D.2
Mirmira, R.G.3
-
32
-
-
0038413922
-
NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice
-
Kojima H, Fujimiya M, Matsumura K, Younan P, Imaeda H, Maeda M, Chan L (2003) NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice. Nat Med 9: 596-603.
-
(2003)
Nat Med
, vol.9
, pp. 596-603
-
-
Kojima, H.1
Fujimiya, M.2
Matsumura, K.3
Younan, P.4
Imaeda, H.5
Maeda, M.6
Chan, L.7
-
33
-
-
22444443484
-
Synergistic activation of the insulin gene promoter by the beta-cell enriched transcription factors MafA, Beta2, and Pdx1
-
Aramata S, Han SI, Yasuda K, Kataoka K (2005) Synergistic activation of the insulin gene promoter by the beta-cell enriched transcription factors MafA, Beta2, and Pdx1. Biochim Biophys Acta 1730: 41-46.
-
(2005)
Biochim Biophys Acta
, vol.1730
, pp. 41-46
-
-
Aramata, S.1
Han, S.I.2
Yasuda, K.3
Kataoka, K.4
-
34
-
-
20344368579
-
MafA is a key regulator of glucose-stimulated insulin secretion
-
Zhang C, Moriguchi T, Kajihara M, Esaki R, Harada A, Shimohata H, Oishi H, Hamada M, Morito N, Hasegawa K, Kudo T, Engel JD, Yamamoto M, Takahashi S (2005) MafA is a key regulator of glucose-stimulated insulin secretion. Mol Cell Biol 25: 4969-4976.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4969-4976
-
-
Zhang, C.1
Moriguchi, T.2
Kajihara, M.3
Esaki, R.4
Harada, A.5
Shimohata, H.6
Oishi, H.7
Hamada, M.8
Morito, N.9
Hasegawa, K.10
Kudo, T.11
Engel, J.D.12
Yamamoto, M.13
Takahashi, S.14
-
35
-
-
34447124165
-
MAFA controls genes implicated in insulin biosynthesis and secretion
-
Wang H, Brun T, Kataoka K, Sharma AJ, Wollheim CB (2007) MAFA controls genes implicated in insulin biosynthesis and secretion. Diabetologia 50: 348-358.
-
(2007)
Diabetologia
, vol.50
, pp. 348-358
-
-
Wang, H.1
Brun, T.2
Kataoka, K.3
Sharma, A.J.4
Wollheim, C.B.5
-
36
-
-
0037484280
-
p38 MAPK is involved in activin A- and hepatocyte growth factor-mediated expression of pro-endocrine gene neurogenin 3 in AR42J-B13 cells
-
Ogihara T, Watada H, Kanno R, Ikeda F, Nomiyama T, Tanaka Y, Nakao A, German MS, Kojima I, Kawamori R. p38 MAPK is involved in activin A- and hepatocyte growth factor-mediated expression of pro-endocrine gene neurogenin 3 in AR42J-B13 cells. J Biol Chem 278: 21693-21700.
-
J Biol Chem
, vol.278
, pp. 21693-21700
-
-
Ogihara, T.1
Watada, H.2
Kanno, R.3
Ikeda, F.4
Nomiyama, T.5
Tanaka, Y.6
Nakao, A.7
German, M.S.8
Kojima, I.9
Kawamori, R.10
|