Analysis of flavonoids from lotus (Nelumbo nucifera) leaves using high performance liquid chromatography/photodiode array detector tandem electrospray ionization mass spectrometry and an extraction method optimized by orthogonal design

Journal of Chromatography A

Volumn 1227, Issue , 2012, Pages 145-153

  Chen, Sha ^a,b,c   Wu, Ben Hong ^b   Fang, Jin Bao ^d   Liu, Yan Ling ^a   Zhang, Hao Hao ^b   Fang, Lin Chuan ^a   Guan, Le ^b   Li, Shao Hua ^a  

^a Wuhan Institute of Botany Chinese Academy of Sciences   (China)

^b INSTITUTE OF BOTANY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d INSTITUTE OF PLANT PROTECTION   (China)

Author keywords

Flavonoids; HPLC; Leaves (Nelumbo); Mass spectrometry

Indexed keywords

ANALYTICAL CONDITIONS; ANALYTICAL METHOD; ARRAY DETECTORS; BIOACTIVE COMPOUNDS; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; EXTRACTION METHOD; EXTRACTION PROTOCOLS; EXTRACTION TIME; FLAVONOID CONTENT; GRADIENT ELUTION; HPLC; IONIZATION MASS SPECTROMETRY; LEAVES (NELUMBO); LOTUS LEAVES; METHANOL-WATER; MULTI-STEP; NELUMBO NUCIFERA; ORTHOGONAL DESIGN; PHOTODIODE ARRAY DETECTIONS;

CHROMATOGRAPHY; FLAVONOIDS; FORMIC ACID; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHANOL; ORGANIC SOLVENTS; PLANTS (BOTANY); SOLVENTS; TISSUE;

OPTIMIZATION;

ACETONITRILE; ASTRAGALIN; FLAVONOID; FORMIC ACID; HYPERIN; ISOQUERCITRIN; ISORHAMNETIN; ISORHAMNETIN 3 GLUCOSIDE; METHANOL; QUERCETIN; RUTOSIDE; UNCLASSIFIED DRUG; WATER;

ACCURACY; ARTICLE; CONTROLLED STUDY; CULTIVAR IDENTIFICATION; DIODE; ELECTROSPRAY MASS SPECTROMETRY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; NELUMBO NUCIFERA; PLANT LEAF; PLANT YIELD; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SOLVENT EXTRACTION; STRUCTURE ANALYSIS; TEMPERATURE MEASUREMENT; VALIDATION PROCESS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLAVONOIDS; LINEAR MODELS; METHANOL; NELUMBO; PLANT LEAVES; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY; WATER;

NELUMBO; NELUMBO NUCIFERA;

EID: 84862779562     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.12.098     Document Type: Article

References (32)

1. Guo H. Genet. Resour. Crop Evol. 2009, 56:323.
2. Kredy H., Huang D., Xie B., He H., Yang E., Tian B., Xiao D. Eur. Food Res. Technol. 2010, 231:387.
3. Mukherjee P., Saha K., Pal M., Saha B. J. Ethnopharmacol. 1997, 58:207.
4. Jung H., Kim J., Chung H., Choi J. Arch. Pharm. Res. 2003, 26:279.
5. Rai S., Wahile A., Mukherjee K., Saha B., Mukherjee P. J. Ethnopharmacol. 2006, 104:322.
6. Jung H., Jung Y., Yoon N., Jeong D., Bae H., Kim D., Na D., Choi J. Food Chem. Toxicol. 2008, 46:3818.
7. Valls J., Millán S., Martí M., Borràs E., Arola L. J. Chromatogr. A 2009, 1216:7143.
8. Li M., Xu Z. Arch. Pharm. Res. 2008, 31:640.
9. Choe J.H., Jang A., Choi J.H., Choi Y.S., Han D.J., Kim H.Y., Lee M.A., Kim H.W., Kim C.J. Food Sci. Biotechnol. 2010, 19:831.
10. Huang B., Ban X.Q., He J.S., Tong J., Tian J., Wang Y.W. Food Chem. 2010, 120:873.
11. Kashiwada Y., Aoshima A., Ikeshiro Y., Chen Y., Furukawa H., Itoigawa M., Fujioka T., Mihashi K., Cosentino L., Morris-Natschke S. Bioorg. Med. Chem. 2005, 13:443.
12. Agnihotri V.J.K., ElSohly H.N., Khan S.I., Jacob M.R., Joshi V.C., Smillie T., Khan I.A., Walker L.A. Phytochem. Lett. 2008, 1:89.
13. Ono Y., Hattori E., Fukaya Y., Imai S., Ohizumi Y. J. Ethnopharmacol. 2006, 106:238.
14. Lin M.C., Kao S.H., Chung P.J., Chan K.C., Yang M.Y., Wang C.J. J. Agric. Food Chem. 2009, 57:5925.
15. Wu C.H., Yang M.Y., Chan K.C., Chung P.J., Ou T.T., Wang C.J. J. Agric. Food Chem. 2010, 58:7075.
16. Ho H., Hsu L., Chan K., Chen H., Wu C., Wang C. Food Chem. Toxicol. 2010, 48:159.
17. Lepiniec L., Debeaujon I., Routaboul J.M., Baudry A., Pourcel L., Nesi N., Caboche M. Annu. Rev. Plant Biol. 2006, 57:405.
18. Goo H., Choi J., Na D. Arch. Pharm. Res. 2009, 32:201.
19. Deng S., Deng Z., Fan Y., Peng Y., Li J., Xiong D., Liu R. J. Chromatogr. B 2009, 877:2487.
20. Castillo-Muñoz N., Gómez-Alonso S., García-Romero E., Hermosín-Gutiérrez I. J. Food Compost. Anal. 2010, 23:699.
21. Kaur P., Chaudhary A., Singh B. J. Pharm. Biomed. Anal. 2009, 50:1060.
22. Schmitzer V., Slatnar A., Veberic R., Stampar F., Solar A. J. Food Sci. 2011, 76:S14.
23. Cao X., Wang C., Pei H., Sun B. J. Chromatogr. A 2009, 1216:4268.
24. Boros B., Jakabová S., Dörnyei á., Horváth G., Pluhár Z., Kilár F., Felinger A. J. Chromatogr. A 2010, 1217:7972.
25. Yang R.Z., Wei X.L., Gao F.F., Wang L.S., Zhang H.J., Xu Y.J., Li C.H., Ge Y.X., Zhang J.J., Zhang J. J. Chromatogr. A 2009, 1216:106.
26. Aberham A., Cicek S.S., Schneider P., Stuppner H. J. Agric. Food Chem. 2010, 58:10817.
27. Fan L., Zhao H.Y., Xu M., Zhou L., Guo H., Han J., Wang B.R., Guo D.A. J. Chromatogr. A 2009, 1216:2063.
28. Abert Vian M., Maingonnat J.F., Chemat F. J. Chromatogr. A 2009, 1216:7700.
29. Justesen U. J. Chromatogr. A 2000, 902:369.
30. Ablajan K., Abliz Z., Shang X.Y., He J.M., Zhang R.P., Shi J.G. J. Mass Spectrom. 2006, 41:352.
31. Elegami A.A., Bates C., Gray A.I., Mackay S.P., Skellern G.G., Waigh R.D. Phytochemistry 2003, 63:727.
32. Gattuso G., Caristi C., Gargiulli C., Bellocco E., Toscano G., Leuzzi U. J. Agric. Food Chem. 2006, 54:3929.