메뉴 건너뛰기




Volumn 121, Issue 3, 2012, Pages 349-361

Modulation of recombinant, α2*, α3* or α4*-nicotinic acetylcholine receptor (nAChR) function by nAChR β3 subunits

Author keywords

ligand gated ion channel; nicotinic acetylcholine receptor(s); receptor structure function

Indexed keywords

ACETYLCHOLINE; ATROPINE; NICOTINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA2; NICOTINIC RECEPTOR ALPHA3; NICOTINIC RECEPTOR ALPHA4; NICOTINIC RECEPTOR BETA2; NICOTINIC RECEPTOR BETA3; NICOTINIC RECEPTOR BETA4; UNCLASSIFIED DRUG;

EID: 84862779353     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07685.x     Document Type: Article
Times cited : (18)

References (32)
  • 1
    • 1642457187 scopus 로고    scopus 로고
    • Pharmacological properties of α9 α10 nicotinic acetylcholine receptors revealed by heterologous expression of subunit chimeras
    • Baker E. R., Zwart R., Sher E., and, Millar N. S., (2004) Pharmacological properties of α9 α10 nicotinic acetylcholine receptors revealed by heterologous expression of subunit chimeras. Mol. Pharmacol. 65, 453-460.
    • (2004) Mol. Pharmacol. , vol.65 , pp. 453-460
    • Baker, E.R.1    Zwart, R.2    Sher, E.3    Millar, N.S.4
  • 2
    • 0034671380 scopus 로고    scopus 로고
    • Stoichiometry of human recombinant neuronal nicotinic receptors containing the b3 subunit expressed in Xenopus oocytes
    • Boorman J. P., Groot-Kormelink P. J., and, Sivilotti L. G., (2000) Stoichiometry of human recombinant neuronal nicotinic receptors containing the b3 subunit expressed in Xenopus oocytes. J. Physiol., 529 (Pt 3), 565-577.
    • (2000) J. Physiol. , vol.529 , Issue.PART 3 , pp. 565-577
    • Boorman, J.P.1    Groot-Kormelink, P.J.2    Sivilotti, L.G.3
  • 3
    • 0242415148 scopus 로고    scopus 로고
    • The effects of β3 subunit incorporation on the pharmacology and single channel properties of oocyte-expressed human α3β4 neuronal nicotinic receptors
    • Boorman J. P., Beato M., Groot-Kormelink P. J., Broadbent S. D., and, Sivilotti L. G., (2003) The effects of β3 subunit incorporation on the pharmacology and single channel properties of oocyte-expressed human α3β4 neuronal nicotinic receptors. J. Biol. Chem. 278, 44033-44040.
    • (2003) J. Biol. Chem. , vol.278 , pp. 44033-44040
    • Boorman, J.P.1    Beato, M.2    Groot-Kormelink, P.J.3    Broadbent, S.D.4    Sivilotti, L.G.5
  • 4
    • 33748927492 scopus 로고    scopus 로고
    • Incorporation of the beta3 subunit has a dominant-negative effect on the function of recombinant central-type neuronal nicotinic receptors
    • Broadbent S., Groot-Kormelink P. J., Krashia P. A., Harkness P. C., Millar N. S., Beato M., and, Sivilotti L. G., (2006) Incorporation of the beta3 subunit has a dominant-negative effect on the function of recombinant central-type neuronal nicotinic receptors. Mol. Pharmacol. 70, 1350-1357.
    • (2006) Mol. Pharmacol. , vol.70 , pp. 1350-1357
    • Broadbent, S.1    Groot-Kormelink, P.J.2    Krashia, P.A.3    Harkness, P.C.4    Millar, N.S.5    Beato, M.6    Sivilotti, L.G.7
  • 5
    • 67650589051 scopus 로고    scopus 로고
    • Pentameric concatenated (α4)(2)(β2)(3) and (α4)(3)(β2)(2) nicotinic acetylcholine receptors: Subunit arrangement determines functional expression
    • Carbone A. L., Moroni M., Groot-Kormelink P. J., and, Bermudez I., (2009) Pentameric concatenated (α4)(2)(β2)(3) and (α4)(3)(β2)(2) nicotinic acetylcholine receptors: subunit arrangement determines functional expression. Br. J. Pharmacol. 156, 970-981.
    • (2009) Br. J. Pharmacol. , vol.156 , pp. 970-981
    • Carbone, A.L.1    Moroni, M.2    Groot-Kormelink, P.J.3    Bermudez, I.4
  • 6
    • 0031967525 scopus 로고    scopus 로고
    • Substitutions of the highly conserved M2 leucine create spontaneously opening rho1 gamma-aminobutyric acid receptors
    • Chang Y., and, Weiss D. S., (1998) Substitutions of the highly conserved M2 leucine create spontaneously opening rho1 gamma-aminobutyric acid receptors. Mol. Pharmacol. 53, 511-523.
    • (1998) Mol. Pharmacol. , vol.53 , pp. 511-523
    • Chang, Y.1    Weiss, D.S.2
  • 7
    • 0030941561 scopus 로고    scopus 로고
    • Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors h α2 β2, h α2 β4, h α3 β2, h α3 β4, h α4 β2, h α4 β4 and h α7 expressed in Xenopus oocytes
    • Chavez-Noriega L. E., Crona J. H., Washburn M. S., Urrutia A., Elliott K. J., and, Johnson E. C., (1997) Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors h α2 β2, h α2 β4, h α3 β2, h α3 β4, h α4 β2, h α4 β4 and h α7 expressed in Xenopus oocytes. J. Pharmacol. Exp. Ther. 280, 346-356.
    • (1997) J. Pharmacol. Exp. Ther. , vol.280 , pp. 346-356
    • Chavez-Noriega, L.E.1    Crona, J.H.2    Washburn, M.S.3    Urrutia, A.4    Elliott, K.J.5    Johnson, E.C.6
  • 8
    • 0348010302 scopus 로고    scopus 로고
    • The β3 nicotinic receptor subunit: A component of α-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors
    • Cui C., Booker T. K., and, Allen R. S., et al. (2003) The β3 nicotinic receptor subunit: a component of α-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors. J. Neurosci. 23, 11045-11053.
    • (2003) J. Neurosci. , vol.23 , pp. 11045-11053
    • Cui, C.1    Booker, T.K.2    Allen, R.S.3
  • 9
    • 80055068688 scopus 로고    scopus 로고
    • Identification of N-terminal, extracellular domain determinants in nicotinic acetylcholine receptor (nAChR) {α}6 subunits that influence effects of wild-type or mutant {β}3 subunits on function of {α}6{β}2*-or {α}6{β}4*-nAChR
    • Dash B., Bhakta M., Chang Y., and, Lukas R. J., (2011a) Identification of N-terminal, extracellular domain determinants in nicotinic acetylcholine receptor (nAChR) {α}6 subunits that influence effects of wild-type or mutant {β}3 subunits on function of {α}6{β}2*-or {α}6{β}4*-nAChR. J. Biol. Chem. 286, 37976-37989.
    • (2011) J. Biol. Chem. , vol.286 , pp. 37976-37989
    • Dash, B.1    Bhakta, M.2    Chang, Y.3    Lukas, R.J.4
  • 10
    • 80055098120 scopus 로고    scopus 로고
    • Reporter mutation studies show that nicotinic acetylcholine receptor (nAChR) {α}5 subunits and/or variants modulate function of {α}6*-nAChRs
    • Dash B., Chang Y., and, Lukas R. J., (2011b) Reporter mutation studies show that nicotinic acetylcholine receptor (nAChR) {α}5 subunits and/or variants modulate function of {α}6*-nAChRs. J. Biol. Chem. 286, 37905-37918.
    • (2011) J. Biol. Chem. , vol.286 , pp. 37905-37918
    • Dash, B.1    Chang, Y.2    Lukas, R.J.3
  • 11
    • 25144467556 scopus 로고    scopus 로고
    • Heterogeneity and selective targeting of neuronal nicotinic acetylcholine receptor (nAChR) subtypes expressed on retinal afferents of the superior colliculus and lateral geniculate nucleus: Identification of a new native nAChR subtype α3β2(α5 or β3) enriched in retinocollicular afferents
    • Gotti C., Moretti M., Zanardi A., et al. (2005) Heterogeneity and selective targeting of neuronal nicotinic acetylcholine receptor (nAChR) subtypes expressed on retinal afferents of the superior colliculus and lateral geniculate nucleus: identification of a new native nAChR subtype α3β2(α5 or β3) enriched in retinocollicular afferents. Mol. Pharmacol. 68, 1162-1171.
    • (2005) Mol. Pharmacol. , vol.68 , pp. 1162-1171
    • Gotti, C.1    Moretti, M.2    Zanardi, A.3
  • 12
    • 60849088886 scopus 로고    scopus 로고
    • Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the α3β4* and α3β3β4* subtypes mediate acetylcholine release
    • Grady S. R., Moretti M., Zoli M., Marks M. J., Zanardi A., Pucci L., Clementi F., and, Gotti C., (2009) Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the α3β4* and α3β3β4* subtypes mediate acetylcholine release. J. Neurosci. 29, 2272-2282.
    • (2009) J. Neurosci. , vol.29 , pp. 2272-2282
    • Grady, S.R.1    Moretti, M.2    Zoli, M.3    Marks, M.J.4    Zanardi, A.5    Pucci, L.6    Clementi, F.7    Gotti, C.8
  • 13
    • 0031023873 scopus 로고    scopus 로고
    • Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32
    • Groot Kormelink P. J., and, Luyten W. H., (1997) Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32. FEBS Lett. 400, 309-314.
    • (1997) FEBS Lett. , vol.400 , pp. 309-314
    • Groot Kormelink, P.J.1    Luyten, W.H.2
  • 14
    • 0032546786 scopus 로고    scopus 로고
    • A reporter mutation approach shows incorporation of the "orphan" subunit beta3 into a functional nicotinic receptor
    • Groot-Kormelink P. J., Luyten W. H., Colquhoun D., and, Sivilotti L. G., (1998) A reporter mutation approach shows incorporation of the "orphan" subunit beta3 into a functional nicotinic receptor. J. Biol. Chem. 273, 15317-15320.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15317-15320
    • Groot-Kormelink, P.J.1    Luyten, W.H.2    Colquhoun, D.3    Sivilotti, L.G.4
  • 15
    • 0034740035 scopus 로고    scopus 로고
    • Formation of functional α3β4α5 human neuronal nicotinic receptors in Xenopus oocytes: A reporter mutation approach
    • Groot-Kormelink P. J., Boorman J. P., and, Sivilotti L. G., (2001) Formation of functional α3β4α5 human neuronal nicotinic receptors in Xenopus oocytes: a reporter mutation approach. Br. J. Pharmacol. 134, 789-796.
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 789-796
    • Groot-Kormelink, P.J.1    Boorman, J.P.2    Sivilotti, L.G.3
  • 16
    • 45749094140 scopus 로고    scopus 로고
    • Roles of accessory subunits in α4β2 nicotinic receptors
    • Kuryatov A., Onksen J., and, Lindstrom J., (2008) Roles of accessory subunits in α4β2 nicotinic receptors. Mol. Pharmacol. 74, 132-143.
    • (2008) Mol. Pharmacol. , vol.74 , pp. 132-143
    • Kuryatov, A.1    Onksen, J.2    Lindstrom, J.3
  • 17
    • 2442657805 scopus 로고    scopus 로고
    • Getting past the asterisk: The subunit composition of presynaptic nicotinic receptors that modulate striatal dopamine release
    • Luetje C. W., (2004) Getting past the asterisk: the subunit composition of presynaptic nicotinic receptors that modulate striatal dopamine release. Mol. Pharmacol. 65, 1333-1335.
    • (2004) Mol. Pharmacol. , vol.65 , pp. 1333-1335
    • Luetje, C.W.1
  • 18
    • 0025934097 scopus 로고
    • Both α- And β-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors
    • Luetje C. W., and, Patrick J., (1991) Both α- and β-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors. J. Neurosci. 11, 837-845.
    • (1991) J. Neurosci. , vol.11 , pp. 837-845
    • Luetje, C.W.1    Patrick, J.2
  • 19
    • 0032970174 scopus 로고    scopus 로고
    • International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits
    • Lukas R. J., Changeux J. P., and, Le Novere N., et al. (1999) International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits. Pharmacol. Rev. 51, 397-401.
    • (1999) Pharmacol. Rev. , vol.51 , pp. 397-401
    • Lukas, R.J.1    Changeux, J.P.2    Le Novere, N.3
  • 20
    • 0035163189 scopus 로고    scopus 로고
    • Functional properties of human nicotinic AChRs expressed by IMR-32 neuroblastoma cells resemble those of α3β4 AChRs expressed in permanently transfected HEK cells
    • Nelson M. E., Wang F., Kuryatov A., Choi C. H., Gerzanich V., and, Lindstrom J., (2001) Functional properties of human nicotinic AChRs expressed by IMR-32 neuroblastoma cells resemble those of α3β4 AChRs expressed in permanently transfected HEK cells. J. Gen. Physiol. 118, 563-582.
    • (2001) J. Gen. Physiol. , vol.118 , pp. 563-582
    • Nelson, M.E.1    Wang, F.2    Kuryatov, A.3    Choi, C.H.4    Gerzanich, V.5    Lindstrom, J.6
  • 21
    • 0037289747 scopus 로고    scopus 로고
    • Alternate stoichiometries of α4β2 nicotinic acetylcholine receptors
    • Nelson M. E., Kuryatov A., Choi C. H., Zhou Y., and, Lindstrom J., (2003) Alternate stoichiometries of α4β2 nicotinic acetylcholine receptors. Mol. Pharmacol. 63, 332-341.
    • (2003) Mol. Pharmacol. , vol.63 , pp. 332-341
    • Nelson, M.E.1    Kuryatov, A.2    Choi, C.H.3    Zhou, Y.4    Lindstrom, J.5
  • 22
    • 0033603351 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors assembled from the α7 and β3 subunits
    • Palma E., Maggi L., Barabino B., Eusebi F., and, Ballivet M., (1999) Nicotinic acetylcholine receptors assembled from the α7 and β3 subunits. J. Biol. Chem. 274, 18335-18340.
    • (1999) J. Biol. Chem. , vol.274 , pp. 18335-18340
    • Palma, E.1    Maggi, L.2    Barabino, B.3    Eusebi, F.4    Ballivet, M.5
  • 23
    • 0347659028 scopus 로고    scopus 로고
    • Nicotine is highly effective at producing desensitization of rat α4β2 neuronal nicotinic receptors
    • Paradiso K. G., and, Steinbach J. H., (2003) Nicotine is highly effective at producing desensitization of rat α4β2 neuronal nicotinic receptors. J. Physiol. 553, 857-871.
    • (2003) J. Physiol. , vol.553 , pp. 857-871
    • Paradiso, K.G.1    Steinbach, J.H.2
  • 24
    • 0037350806 scopus 로고    scopus 로고
    • Interactions of atropine with heterologously expressed and native α3 subunit-containing nicotinic acetylcholine receptors
    • Parker J. C., Sarkar D., Quick M. W., and, Lester R. A., (2003) Interactions of atropine with heterologously expressed and native α3 subunit-containing nicotinic acetylcholine receptors. Br. J. Pharmacol. 138, 801-810.
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 801-810
    • Parker, J.C.1    Sarkar, D.2    Quick, M.W.3    Lester, R.A.4
  • 25
    • 0035726679 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptor subunit knockout mice: Physiological and behavioral phenotypes and possible clinical implications
    • Picciotto M. R., Caldarone B. J., Brunzell D. H., Zachariou V., Stevens T. R., and, King S. L., (2001) Neuronal nicotinic acetylcholine receptor subunit knockout mice: physiological and behavioral phenotypes and possible clinical implications. Pharmacol. Ther. 92, 89-108.
    • (2001) Pharmacol. Ther. , vol.92 , pp. 89-108
    • Picciotto, M.R.1    Caldarone, B.J.2    Brunzell, D.H.3    Zachariou, V.4    Stevens, T.R.5    King, S.L.6
  • 26
    • 2442653986 scopus 로고    scopus 로고
    • Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice
    • Salminen O., Murphy K. L., McIntosh J. M., Drago J., Marks M. J., Collins A. C., and, Grady S. R., (2004) Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice. Mol. Pharmacol. 65, 1526-1535.
    • (2004) Mol. Pharmacol. , vol.65 , pp. 1526-1535
    • Salminen, O.1    Murphy, K.L.2    McIntosh, J.M.3    Drago, J.4    Marks, M.J.5    Collins, A.C.6    Grady, S.R.7
  • 27
    • 0033819579 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor subunit mRNA expression and channel function in medial habenula neurons
    • Sheffield E. B., Quick M. W., and, Lester R. A., (2000) Nicotinic acetylcholine receptor subunit mRNA expression and channel function in medial habenula neurons. Neuropharmacology 39, 2591-2603.
    • (2000) Neuropharmacology , vol.39 , pp. 2591-2603
    • Sheffield, E.B.1    Quick, M.W.2    Lester, R.A.3
  • 28
    • 33847128877 scopus 로고    scopus 로고
    • Ca2 + permeability of the (α4)3(β2)2 stoichiometry greatly exceeds that of (α4)2(β2)3 human acetylcholine receptors
    • Tapia L., Kuryatov A., and, Lindstrom J., (2007) Ca2 + permeability of the (α4)3(β2)2 stoichiometry greatly exceeds that of (α4)2(β2)3 human acetylcholine receptors. Mol. Pharmacol. 71, 769-776.
    • (2007) Mol. Pharmacol. , vol.71 , pp. 769-776
    • Tapia, L.1    Kuryatov, A.2    Lindstrom, J.3
  • 29
    • 67549104036 scopus 로고    scopus 로고
    • Kinetics of desensitization and recovery from desensitization for human α4β2-nicotinic acetylcholine receptors stably expressed in SH-EP1 cells
    • Yu K. D., Liu Q., Wu J., and, Lukas R. J., (2009) Kinetics of desensitization and recovery from desensitization for human α4β2- nicotinic acetylcholine receptors stably expressed in SH-EP1 cells. Acta Pharmacol. Sin. 30, 805-817.
    • (2009) Acta Pharmacol. Sin. , vol.30 , pp. 805-817
    • Yu, K.D.1    Liu, Q.2    Wu, J.3    Lukas, R.J.4
  • 30
    • 0030842275 scopus 로고    scopus 로고
    • Potentiation and inhibition of neuronal nicotinic receptors by atropine: Competitive and noncompetitive effects
    • Zwart R., and, Vijverberg H. P., (1997) Potentiation and inhibition of neuronal nicotinic receptors by atropine: competitive and noncompetitive effects. Mol. Pharmacol. 52, 886-895.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 886-895
    • Zwart, R.1    Vijverberg, H.P.2
  • 31
    • 0032426910 scopus 로고    scopus 로고
    • Four pharmacologically distinct subtypes of α4β2 nicotinic acetylcholine receptor expressed in Xenopus laevis oocytes
    • Zwart R., and, Vijverberg H. P., (1998) Four pharmacologically distinct subtypes of α4β2 nicotinic acetylcholine receptor expressed in Xenopus laevis oocytes. Mol. Pharmacol. 54, 1124-1131.
    • (1998) Mol. Pharmacol. , vol.54 , pp. 1124-1131
    • Zwart, R.1    Vijverberg, H.P.2
  • 32
    • 0033047491 scopus 로고    scopus 로고
    • Physostigmine and atropine potentiate and inhibit neuronal α4 β4 nicotinic receptors
    • Zwart R., Van Kleef R. G., and, Vijverberg H. P., (1999) Physostigmine and atropine potentiate and inhibit neuronal α4 β4 nicotinic receptors. Ann. N Y Acad. Sci. 868, 636-639.
    • (1999) Ann. N y Acad. Sci. , vol.868 , pp. 636-639
    • Zwart, R.1    Van Kleef, R.G.2    Vijverberg, H.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.