Reporter mutation studies show that nicotinic acetylcholine receptor (nAChR) α5 subunits and/or variants modulate function of α6*-nAChR

Journal of Biological Chemistry

Volumn 286, Issue 44, 2011, Pages 37905-37918

  Dash, Bhagirathi ^a,b   Chang, Yongchang ^a   Lukas, Ronald J ^b  

^a BARROW NEUROLOGICAL INSTITUTE   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CO-EXPRESSION; EXTRACELLULAR; EXTRACELLULAR DOMAINS; FUNCTIONAL EXPRESSION; N-TERMINAL DOMAINS; N-TERMINALS; NEUROLOGICAL DISEASE; NICOTINIC ACETYLCHOLINE RECEPTORS; NICOTINIC ACETYLCHOLINE RECEPTORS (NACHR); SECOND TRANSMEMBRANE DOMAIN; TRANS-MEMBRANE DOMAINS; WILD TYPES;

ACTIVATION ANALYSIS; AMINO ACIDS; MAMMALS;

TOBACCO;

MECAMYLAMINE; MUTANT PROTEIN; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA5; NICOTINIC RECEPTOR ALPHA5BETA3; NICOTINIC RECEPTOR ALPHA6; NICOTINIC RECEPTOR ALPHA6ALPHA3; NICOTINIC RECEPTOR ALPHA6ALPHA5; NICOTINIC RECEPTOR ALPHA6BETA2; NICOTINIC RECEPTOR ALPHA6BETA4; NICOTINIC RECEPTOR BETA2; NICOTINIC RECEPTOR BETA4; RECEPTOR SUBUNIT; SERINE; UNCLASSIFIED DRUG; VALINE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHIMERA; CONTROLLED STUDY; GAIN OF FUNCTION MUTATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; WILD TYPE;

ANIMALS; CYTOPLASM; DNA, COMPLEMENTARY; ELECTROPHYSIOLOGY; FEMALE; HUMANS; LIGANDS; MUTATION; NERVE TISSUE PROTEINS; NICOTINE; OOCYTES; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NICOTINIC; RECOMBINANT FUSION PROTEINS; XENOPUS LAEVIS;

EID: 80055098120     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.264044     Document Type: Article

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