An analog of BIX-01294 selectively inhibits a family of histone H3 lysine 9 jumonji demethylases

Journal of Molecular Biology

Volumn 416, Issue 3, 2012, Pages 319-327

  Upadhyay, Anup K ^a   Rotili, Dante ^b   Han, Ji Woong ^a   Hu, Ruogu ^a   Chang, Yanqi ^a   Labella, Donatella ^b   Zhang, Xing ^a   Yoon, Young Sup ^a   Mai, Antonello ^b   Cheng, Xiaodong ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

BIX analogs; enzymatic inhibition; epigenetics; histone lysine demethylation

Indexed keywords

BIX 01294; DIADENOSINE TETRAPHOSPHATE; G9A PROTEIN; HISTONE DEACETYLASE INHIBITOR; HISTONE DEMETHYLASE; HISTONE H3 LYSINE 9; KIAA 1718; PIPERIDINE; PROTEIN DERIVATIVE; PROTEIN E67; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CRYSTALLOGRAPHY; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

EID: 84862777760     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.12.036     Document Type: Article

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