Rsk-mediated phosphorylation and 14-3-3ε binding of Apaf-1 suppresses cytochrome c-induced apoptosis

EMBO Journal

Volumn 31, Issue 5, 2012, Pages 1279-1292

  Kim, Jiyeon ^a   Parrish, Amanda B ^a   Kurokawa, Manabu ^a   Matsuura, Kenkyo ^a   Freel, Christopher D ^a   Andersen, Joshua L ^a   Johnson, Carrie E ^a   Kornbluth, Sally ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

14 3 3; Apaf 1; apoptosis; cytochrome c; Rsk

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE; CYTOCHROME C OXIDASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN 14 3 3; PROTEIN 14 3 3 EPSILON; S6 KINASE; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL SURVIVAL; CELL TYPE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

14-3-3 PROTEINS; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; CELL LINE; CERCOPITHECUS AETHIOPS; CYTOCHROMES C; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; RIBOSOMAL PROTEIN S6 KINASES;

EID: 84862777482     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.491     Document Type: Article

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