Experimental agents which inhibit hepatocarcinogenesis

Oncology

Volumn 75, Issue SUPPL. 1, 2008, Pages 17-21

  Yoon, Jung Hwan ^a   Lee, Hyo Suk ^a  

^a Seoul National University College of Medicine   (South Korea)

Author keywords

Apoptosis; Hepatocellular carcinoma; Hypoxia

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONAMIDE; ADRENOMEDULLIN; ADRENOMEDULLIN INHIBITOR; ANGIOGENESIS INHIBITOR; BROMOPYRUVIC ACID; DENILEUKIN DIFTITOX; HEXOKINASE; HEXOKINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; RETINOIC ACID; RETINOIC ACID BINDING PROTEIN; RETINOIC ACID BINDING PROTEIN 2; UNCLASSIFIED DRUG;

ANTIANGIOGENIC THERAPY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER INHIBITION; CELL DEATH; CELL GROWTH; CELL HYPOXIA; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL EFFECTIVENESS; CONFERENCE PAPER; DRUG EFFICACY; DRUG POTENTIATION; ENZYME INDUCTION; ENZYME INHIBITION; HEPATOMA CELL; HUMAN; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; TUMOR VASCULARIZATION;

ANGIOGENESIS INHIBITORS; ANOXIA; ANTICARCINOGENIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; HUMANS; LIVER NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC;

EID: 58149101479     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000173420     Document Type: Conference Paper

References (6)

1. Gwak GY, Yoon JH, Kim KM, Lee HS, Chung JW, Gores GJ: Hypoxia stimulates proliferation of human hepatoma cells through the induction of hexokinase II expression. J Hepatol 2005;42:358-364.
2. Kim W, Yoon JH, Jeong JM, Cheon GJ, Lee TS, Yang JI, Lee HS: Apoptosis-inducing antitumor efficacy of hexokinase II inhibitor in hepatocellular carcinoma. Mol Cancer Ther 2007;6:2554-2562.
3. Yoon JH, Lee JH, Lee HS, et al: Cellular retinoic acid binding protein II induction by hypoxia attenuates enhanced retinoic acid-induced apoptosis in hypoxic hepatocellular carcinoma cells (abstract). Hepatol Int 2008; 1: Abstract.
4. Park SC, Yoon JH, Lee JH, Yu SJ, Myung SJ, Kim W, Lee HS: Hypoxia-inducible adrenomedullin accelerates hepatocellular carcinoma cell growth. Cancer Lett 2008, Jul 24 [Epub ahead of print].
5. Myung SJ, Yoon JH, Kim BH, et al: Enhanced interleukin-2 diphtheria toxin conjugate-induced growth suppression in retinoic acidtreated hypoxic hepatocellular carcinoma cells (abstract 434). J Hepatol 2008;48:S166.
6. Yoon JH, Myung SJ, Gwak GY, et al: Inhibition of hypoxia-inducible carbonic anhydrase IX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis (abstract 445). J Hepatol 2008;48:S170.