메뉴 건너뛰기




Volumn 95, Issue 4, 2012, Pages 267-276

Diffuse endocrine system, neuroendocrine tumors and immunity: What's new?

Author keywords

Cortistatin; Immunity; Neuroendocrine tumors; Neuropeptides; Somatostatin

Indexed keywords

CORTISTATIN; NEUROPEPTIDE; SOMATOSTATIN;

EID: 84862754168     PISSN: 00283835     EISSN: 14230194     Source Type: Journal    
DOI: 10.1159/000334612     Document Type: Review
Times cited : (48)

References (76)
  • 2
    • 2342606044 scopus 로고    scopus 로고
    • The 'normal' endocrine cell of the gut: Changing concepts and new evidences
    • Rindi G, Leiter AB, Kopin AS, Bordi C, Solcia E: The 'normal' endocrine cell of the gut: changing concepts and new evidences. Ann NY Acad Sci 2004;1014:1-12.
    • (2004) Ann NY Acad Sci , vol.1014 , pp. 1-12
    • Rindi, G.1    Leiter, A.B.2    Kopin, A.S.3    Bordi, C.4    Solcia, E.5
  • 3
    • 76749098737 scopus 로고    scopus 로고
    • Overview of the immune response
    • Chaplin DD: Overview of the immune response. J Allergy Clin Immunol 2010;125(suppl 2):S3-S23.
    • (2010) J Allergy Clin Immunol , vol.125 , Issue.SUPPL. 2
    • Chaplin, D.D.1
  • 9
    • 33847782893 scopus 로고    scopus 로고
    • Expression, pharmacology, and functional role of somatostatin receptor subtypes 1 and 2 in human macrophages
    • Armani C, Catalani E, Balbarini A, Bagnoli P, Cervia D: Expression, pharmacology, and functional role of somatostatin receptor subtypes 1 and 2 in human macrophages. J Leukoc Biol 2007;81:845-855.
    • (2007) J Leukoc Biol , vol.81 , pp. 845-855
    • Armani, C.1    Catalani, E.2    Balbarini, A.3    Bagnoli, P.4    Cervia, D.5
  • 10
    • 27744570118 scopus 로고    scopus 로고
    • Systemic distribution of somatostatin receptor subtypes in human: An immunohistochemical study
    • Taniyama Y, Suzuki T, Mikami Y, Moriya T, Satomi S, Sasano H: Systemic distribution of somatostatin receptor subtypes in human: an immunohistochemical study. Endocr J 2005;52:605-611.
    • (2005) Endocr J , vol.52 , pp. 605-611
    • Taniyama, Y.1    Suzuki, T.2    Mikami, Y.3    Moriya, T.4    Satomi, S.5    Sasano, H.6
  • 11
    • 33750626838 scopus 로고    scopus 로고
    • Expression pattern of somatostatin receptor subtypes 1-5 in human skin: An immunohistochemical study of healthy subjects and patients with psoriasis or atopic dermatitis
    • Hagströmer L, Emtestam L, Stridsberg M, Talme T: Expression pattern of somatostatin receptor subtypes 1-5 in human skin: an immunohistochemical study of healthy subjects and patients with psoriasis or atopic dermatitis. Exp Dermatol 2006;15:950-957.
    • (2006) Exp Dermatol , vol.15 , pp. 950-957
    • Hagströmer, L.1    Emtestam, L.2    Stridsberg, M.3    Talme, T.4
  • 12
    • 84862774353 scopus 로고    scopus 로고
    • Immunohistochemical localization and quantitative expression of somatostatin receptors in normal human spleen and thymus: Implications for the in vivo visualization during somatostatin receptor scintigraphy
    • Epub ahead of print
    • Ferone D, Pivonello R, Kwekkeboom DJ, Gatto F, Ameri P, Colao A, de Krijger RR, Minuto F, Lamberts SW, van Hagen PM, Hofland LJ: Immunohistochemical localization and quantitative expression of somatostatin receptors in normal human spleen and thymus: implications for the in vivo visualization during somatostatin receptor scintigraphy. J Endocrinol Invest 2011, Epub ahead of print.
    • (2011) J Endocrinol Invest
    • Ferone, D.1    Pivonello, R.2    Kwekkeboom, D.J.3    Gatto, F.4    Ameri, P.5    Colao, A.6    De Krijger, R.R.7    Minuto, F.8    Lamberts, S.W.9    Van Hagen, P.M.10    Hofland, L.J.11
  • 14
    • 33749443206 scopus 로고    scopus 로고
    • Inhibitory effect of somatostatin on inflammation and nociception
    • Pintér E, Helyes Z, Szolcsányi J: Inhibitory effect of somatostatin on inflammation and nociception. Pharmacol Ther 2006;112:440-456.
    • (2006) Pharmacol Ther , vol.112 , pp. 440-456
    • Pintér, E.1    Helyes, Z.2    Szolcsányi, J.3
  • 15
    • 18744420570 scopus 로고    scopus 로고
    • Mustard oil induces a transient receptor potential vanilloid 1 receptor-independent neurogenic inflammation and a non-neurogenic cellular inflammatory component in mice
    • Bánvölgyi A, Pozsgai G, Brain SD, Helyes ZS, Szolcsányi J, Ghosh M, Melegh B, Pintér E: Mustard oil induces a transient receptor potential vanilloid 1 receptor-independent neurogenic inflammation and a non-neurogenic cellular inflammatory component in mice. Neuroscience 2004;125:449-459.
    • (2004) Neuroscience , vol.125 , pp. 449-459
    • Bánvölgyi, A.1    Pozsgai, G.2    Brain, S.D.3    Helyes, Z.S.4    Szolcsányi, J.5    Ghosh, M.6    Melegh, B.7    Pintér, E.8
  • 16
    • 33846202164 scopus 로고    scopus 로고
    • Sensitization of pelvic nerve afferents and mast cell infiltration in the urinary bladder following chronic colonic irritation is mediated by neuropeptides
    • Ustinova EE, Gutkin DW, Pezzone MA: Sensitization of pelvic nerve afferents and mast cell infiltration in the urinary bladder following chronic colonic irritation is mediated by neuropeptides. Am J Physiol Renal Physiol 2007;292:F123-F130.
    • (2007) Am J Physiol Renal Physiol , vol.292
    • Ustinova, E.E.1    Gutkin, D.W.2    Pezzone, M.A.3
  • 22
    • 0034665089 scopus 로고    scopus 로고
    • Somatostatin through its specific receptor inhibits spontaneous and TNF-alpha- and bacteria-induced IL-8 and IL-1 beta secretion from intestinal epithelial cells
    • Chowers Y, Cahalon L, Lahav M, Schor H, Tal R, Bar-Meir S, Levite M: Somatostatin through its specific receptor inhibits spontaneous and TNF-alpha- and bacteria-induced IL-8 and IL-1 beta secretion from intestinal epithelial cells. J Immunol 2000;165:2955-2961.
    • (2000) J Immunol , vol.165 , pp. 2955-2961
    • Chowers, Y.1    Cahalon, L.2    Lahav, M.3    Schor, H.4    Tal, R.5    Bar-Meir, S.6    Levite, M.7
  • 23
    • 0029087249 scopus 로고
    • Somatostatin may participate in the antiinflammatory actions of glucocorticoids
    • Karalis K, Mastorakos G, Sano H, Wilder RL, Chrousos GP: Somatostatin may participate in the antiinflammatory actions of glucocorticoids. Endocrinology 1995;136:4133-4138.
    • (1995) Endocrinology , vol.136 , pp. 4133-4138
    • Karalis, K.1    Mastorakos, G.2    Sano, H.3    Wilder, R.L.4    Chrousos, G.P.5
  • 27
    • 0242666360 scopus 로고    scopus 로고
    • MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion
    • Robas N, Mead E, Fidock M: MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion. J Biol Chem 2003;278:44400-44404.
    • (2003) J Biol Chem , vol.278 , pp. 44400-44404
    • Robas, N.1    Mead, E.2    Fidock, M.3
  • 28
    • 33645080443 scopus 로고    scopus 로고
    • Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia
    • Gonzalez-Rey E, Chorny A, Robledo G, Delgado M: Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia. J Exp Med 2006;203:563-571.
    • (2006) J Exp Med , vol.203 , pp. 563-571
    • Gonzalez-Rey, E.1    Chorny, A.2    Robledo, G.3    Delgado, M.4
  • 30
    • 34047199656 scopus 로고    scopus 로고
    • Therapeutic effect of cortistatin on experimental arthritis by downregulating inflammatory and Th1 responses
    • Gonzalez-Rey E, Chorny A, Del Moral RG, Varela N, Delgado M: Therapeutic effect of cortistatin on experimental arthritis by downregulating inflammatory and Th1 responses. Ann Rheum Dis 2007;66:582-588.
    • (2007) Ann Rheum Dis , vol.66 , pp. 582-588
    • Gonzalez-Rey, E.1    Chorny, A.2    Del Moral, R.G.3    Varela, N.4    Delgado, M.5
  • 31
    • 68049114483 scopus 로고    scopus 로고
    • Diverging effects of cortistatin and somatostatin on the production and release of prostanoids from rat cortical microglia and astrocytes
    • Dello Russo C, Lisi L, Navarra P, Tringali G: Diverging effects of cortistatin and somatostatin on the production and release of prostanoids from rat cortical microglia and astrocytes. J Neuroimmunol 2009;213:78-83.
    • (2009) J Neuroimmunol , vol.213 , pp. 78-83
    • Dello Russo, C.1    Lisi, L.2    Navarra, P.3    Tringali, G.4
  • 32
    • 33845900208 scopus 로고    scopus 로고
    • Regulation of immune tolerance by anti-inflammatory neuropeptides
    • Gonzalez-Rey E, Chorny A, Delgado M: Regulation of immune tolerance by anti-inflammatory neuropeptides. Nat Rev Immunol 2007;7:52-63.
    • (2007) Nat Rev Immunol , vol.7 , pp. 52-63
    • Gonzalez-Rey, E.1    Chorny, A.2    Delgado, M.3
  • 33
    • 36749079092 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide inhibits cyclooxygenase-2 expression in activated macrophages, microglia, and dendritic cells
    • Gonzalez-Rey E, Delgado M: Vasoactive intestinal peptide inhibits cyclooxygenase-2 expression in activated macrophages, microglia, and dendritic cells. Brain Behav Immun 2008;22:35-41.
    • (2008) Brain Behav Immun , vol.22 , pp. 35-41
    • Gonzalez-Rey, E.1    Delgado, M.2
  • 34
    • 43449087928 scopus 로고    scopus 로고
    • Neuropeptides rescue mice from lethal sepsis by down-regulating secretion of the late-acting inflammatory mediator high mobility group box 1
    • Chorny A, Delgado M: Neuropeptides rescue mice from lethal sepsis by down-regulating secretion of the late-acting inflammatory mediator high mobility group box 1. Am J Pathol 2008;172:1297-1307.
    • (2008) Am J Pathol , vol.172 , pp. 1297-1307
    • Chorny, A.1    Delgado, M.2
  • 35
    • 50949098239 scopus 로고    scopus 로고
    • Ghrelin protects against experimental sepsis by inhibiting high-mobility group box 1 release and by killing bacteria
    • Chorny A, Anderson P, Gonzalez-Rey E, Delgado M: Ghrelin protects against experimental sepsis by inhibiting high-mobility group box 1 release and by killing bacteria. J Immunol 2008;180:8369-8377.
    • (2008) J Immunol , vol.180 , pp. 8369-8377
    • Chorny, A.1    Anderson, P.2    Gonzalez-Rey, E.3    Delgado, M.4
  • 36
    • 77955272722 scopus 로고    scopus 로고
    • Neuropeptides: Keeping the balance between pathogen immunity and immune tolerance
    • Gonzalez-Rey E, Ganea D, Delgado M: Neuropeptides: keeping the balance between pathogen immunity and immune tolerance. Curr Opin Pharmacol 2010;10:473-481.
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 473-481
    • Gonzalez-Rey, E.1    Ganea, D.2    Delgado, M.3
  • 39
    • 38149075167 scopus 로고    scopus 로고
    • Increased chromogranin A levels indicate sympathetic hyperactivity in patients with rheumatoid arthritis and systemic lupus erythematosus
    • Capellino S, Lowin T, Angele P, Falk W, Grifka J, Straub RH: Increased chromogranin A levels indicate sympathetic hyperactivity in patients with rheumatoid arthritis and systemic lupus erythematosus. J Rheumatol 2008;35:91-99.
    • (2008) J Rheumatol , vol.35 , pp. 91-99
    • Capellino, S.1    Lowin, T.2    Angele, P.3    Falk, W.4    Grifka, J.5    Straub, R.H.6
  • 40
    • 33751304132 scopus 로고    scopus 로고
    • Increased serum levels of chromogranin A in male smokers with airway obstruction
    • Sørhaug S, Langhammer A, Waldum HL, Hveem K, Steinshamn S: Increased serum levels of chromogranin A in male smokers with airway obstruction. Eur Respir J 2006;28542-28548.
    • (2006) Eur Respir J , pp. 28542-28548
    • Sørhaug, S.1    Langhammer, A.2    Waldum, H.L.3    Hveem, K.4    Steinshamn, S.5
  • 43
    • 0032514760 scopus 로고    scopus 로고
    • Neuropeptides, by direct interaction with T cells, induce cytokine secretion and break the commitment to a distinct T helper phenotype
    • Levite M: Neuropeptides, by direct interaction with T cells, induce cytokine secretion and break the commitment to a distinct T helper phenotype. Proc Natl Acad Sci USA 1998;95:12544-12549.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12544-12549
    • Levite, M.1
  • 44
    • 0033772704 scopus 로고    scopus 로고
    • The somatostatin immunoregulatory circuit present at sites of chronic inflammation
    • Weinstock JV, Elliott D: The somatostatin immunoregulatory circuit present at sites of chronic inflammation. Eur J Endocrinol 2000;143(suppl 1):S15-S19.
    • (2000) Eur J Endocrinol , vol.143 , Issue.SUPPL. 1
    • Weinstock, J.V.1    Elliott, D.2
  • 46
    • 79960113599 scopus 로고    scopus 로고
    • Ingested (oral) SST inhibits EAE
    • Brod SA, Hood ZM: Ingested (oral) SST inhibits EAE. Autoimmunity 2011;44:437-443.
    • (2011) Autoimmunity , vol.44 , pp. 437-443
    • Brod, S.A.1    Hood, Z.M.2
  • 47
    • 74049164847 scopus 로고    scopus 로고
    • Regulatory T cells exert checks and balances on self tolerance and autoimmunity
    • Wing K, Sakaguchi S: Regulatory T cells exert checks and balances on self tolerance and autoimmunity. Nat Immunol 2010;11:7-13.
    • (2010) Nat Immunol , vol.11 , pp. 7-13
    • Wing, K.1    Sakaguchi, S.2
  • 48
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY: Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003;4:330-336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 49
    • 0035876913 scopus 로고    scopus 로고
    • A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood
    • Yamagiwa S, Gray JD, Hashimoto S, Horwitz DA: A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood. J Immunol 2001;166:7282-7289.
    • (2001) J Immunol , vol.166 , pp. 7282-7289
    • Yamagiwa, S.1    Gray, J.D.2    Hashimoto, S.3    Horwitz, D.A.4
  • 50
    • 77951980124 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide induces cell cycle arrest and regulatory functions in human T cells at multiple levels
    • Anderson P, Gonzalez-Rey E: Vasoactive intestinal peptide induces cell cycle arrest and regulatory functions in human T cells at multiple levels. Mol Cell Biol 2010;30:2537-2551.
    • (2010) Mol Cell Biol , vol.30 , pp. 2537-2551
    • Anderson, P.1    Gonzalez-Rey, E.2
  • 52
    • 70449707793 scopus 로고    scopus 로고
    • Induction of alloantigen-specific human T regulatory cells by vasoactive intestinal peptide
    • Pozo D, Anderson P, Gonzalez-Rey E: Induction of alloantigen-specific human T regulatory cells by vasoactive intestinal peptide. J Immunol 2009;183:4346-4359.
    • (2009) J Immunol , vol.183 , pp. 4346-4359
    • Pozo, D.1    Anderson, P.2    Gonzalez-Rey, E.3
  • 53
    • 73349110962 scopus 로고    scopus 로고
    • Control of allograft rejection in mice by applying a novel neuropeptide, cortistatin
    • Wang J, Zhao R, Zhang F, Li J, Huo B, Cao Y, Dou K: Control of allograft rejection in mice by applying a novel neuropeptide, cortistatin. Adv Ther 2008;25:1331-1341.
    • (2008) Adv Ther , vol.25 , pp. 1331-1341
    • Wang, J.1    Zhao, R.2    Zhang, F.3    Li, J.4    Huo, B.5    Cao, Y.6    Dou, K.7
  • 54
    • 79955481276 scopus 로고    scopus 로고
    • Neuropeptides of human thymus in normal and pathological conditions
    • DOI:10.1016/j.peptides.2011.01.022
    • Mignini F, Sabbatini M, D'Andrea V, Cavallotti C: Neuropeptides of human thymus in normal and pathological conditions. Peptides DOI:10.1016/j.peptides. 2011.01.022.
    • Peptides
    • Mignini, F.1    Sabbatini, M.2    D'Andrea, V.3    Cavallotti, C.4
  • 55
    • 52649121939 scopus 로고    scopus 로고
    • Thiorphan-induced survival and proliferation of rat thymocytes by activation of Akt/survivin pathway and inhibition of caspase-3 activity
    • Amantini C, Mosca M, Lucciarini R, Perfumi MC, Santoni G: Thiorphan-induced survival and proliferation of rat thymocytes by activation of Akt/survivin pathway and inhibition of caspase-3 activity. J Pharmacol Exp Ther 2008;327:215-225.
    • (2008) J Pharmacol Exp Ther , vol.327 , pp. 215-225
    • Amantini, C.1    Mosca, M.2    Lucciarini, R.3    Perfumi, M.C.4    Santoni, G.5
  • 56
    • 33751077347 scopus 로고    scopus 로고
    • Immunesurveillance by dendritic cells: Potential implication for immunotherapy of endocrine cancers
    • Schott M: Immunesurveillance by dendritic cells: potential implication for immunotherapy of endocrine cancers. Endocr Relat Cancer 2006;13:779-795.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 779-795
    • Schott, M.1
  • 58
    • 69749110763 scopus 로고    scopus 로고
    • ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Biotherapy
    • Mallorca Consensus Conference participants; European Neuroendocrine Tumor Society
    • Oberg K, Ferone D, Kaltsas G, Knigge UP, Taal B, Plöckinger U; Mallorca Consensus Conference participants; European Neuroendocrine Tumor Society: ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: biotherapy. Neuroendocrinology 2009;90:209-213.
    • (2009) Neuroendocrinology , vol.90 , pp. 209-213
    • Oberg, K.1    Ferone, D.2    Kaltsas, G.3    Knigge, U.P.4    Taal, B.5    Plöckinger, U.6
  • 60
  • 61
    • 0041664066 scopus 로고    scopus 로고
    • Expression of HLA class I/II antigens and T cell immune response in human neuroendocrine tumors of the pancreas
    • Ryschich E, Autschbach F, Eisold S, Klar E, Buchler MW, Schmidt J: Expression of HLA class I/II antigens and T cell immune response in human neuroendocrine tumors of the pancreas. Tissue Antigens 2003;62:48-54.
    • (2003) Tissue Antigens , vol.62 , pp. 48-54
    • Ryschich, E.1    Autschbach, F.2    Eisold, S.3    Klar, E.4    Buchler, M.W.5    Schmidt, J.6
  • 62
    • 65349163589 scopus 로고    scopus 로고
    • Midgut carcinoid patients display increased numbers of regulatory T cells in peripheral blood with infiltration into tumor tissue
    • Vikman S, Sommaggio R, De La Torre M, Oberg K, Essand M, Giandomenico V, Loskog A, Totterman TH: Midgut carcinoid patients display increased numbers of regulatory T cells in peripheral blood with infiltration into tumor tissue. Acta Oncol 2009;48:391-400.
    • (2009) Acta Oncol , vol.48 , pp. 391-400
    • Vikman, S.1    Sommaggio, R.2    De La Torre, M.3    Oberg, K.4    Essand, M.5    Giandomenico, V.6    Loskog, A.7    Totterman, T.H.8
  • 68
    • 0035139369 scopus 로고    scopus 로고
    • Human small cell lung carcinoma and carcinoid tumor regulate dendritic cell maturation and function
    • Katsenelson NS, Shurin GV, Bykovskaia SN, Shogan J, Shurin MR: Human small cell lung carcinoma and carcinoid tumor regulate dendritic cell maturation and function. Mod Pathol 2001;14:40-45.
    • (2001) Mod Pathol , vol.14 , pp. 40-45
    • Katsenelson, N.S.1    Shurin, G.V.2    Bykovskaia, S.N.3    Shogan, J.4    Shurin, M.R.5
  • 69
    • 77954721060 scopus 로고    scopus 로고
    • Regulatory T cells in tumor immunity
    • Nishikawa H, Sakaguchi S: Regulatory T cells in tumor immunity. Int J Cancer 2010;127:759-767.
    • (2010) Int J Cancer , vol.127 , pp. 759-767
    • Nishikawa, H.1    Sakaguchi, S.2
  • 70
    • 38549094141 scopus 로고    scopus 로고
    • Mast cells have prognostic value in Merkel cell carcinoma
    • Beer TW, Ng LB, Murray K: Mast cells have prognostic value in Merkel cell carcinoma. Am J Dermatopathol 2008;30:27-30.
    • (2008) Am J Dermatopathol , vol.30 , pp. 27-30
    • Beer, T.W.1    Ng, L.B.2    Murray, K.3
  • 71
    • 0033393767 scopus 로고    scopus 로고
    • Dendritic cell immunotherapy induces antitumour response in parathyroid carcinoma and neuroendocrine pancreas carcinoma
    • Schott M, Seissler J, Feldkamp J, von Schilling C, Scherbaum WA: Dendritic cell immunotherapy induces antitumour response in parathyroid carcinoma and neuroendocrine pancreas carcinoma. Horm Metab Res 1999;31:662-664.
    • (1999) Horm Metab Res , vol.31 , pp. 662-664
    • Schott, M.1    Seissler, J.2    Feldkamp, J.3    Von Schilling, C.4    Scherbaum, W.A.5
  • 76
    • 78650588402 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide loss leads to impaired CNS parenchymal T-cell infiltration and resistance to experimental autoimmune encephalomyelitis
    • Abad C, Tan YV, Lopez R, Nobuta H, Dong H, Phan P, Feng JM, Campagnoni AT, Waschek JA: Vasoactive intestinal peptide loss leads to impaired CNS parenchymal T-cell infiltration and resistance to experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 2010;107:19555-19560.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 19555-19560
    • Abad, C.1    Tan, Y.V.2    Lopez, R.3    Nobuta, H.4    Dong, H.5    Phan, P.6    Feng, J.M.7    Campagnoni, A.T.8    Waschek, J.A.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.