Neuroendocrine carcinoma associated with X-linked hyper-immunoglobulin M syndrome: Report of four cases and review of the literature

Clinical Immunology

Volumn 129, Issue 3, 2008, Pages 455-461

  Erdos, Melinda ^a   Garami, Miklós ^b   Rákóczi, Éva ^a   Zalatnai, Attila ^b   Steinbach, Daniel ^c   Baumann, Ulrich ^d   Kropshofer, Gabrielle ^e   Tóth, Beáta ^a   Maródi, László ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c UNIVERSITY HOSPITAL ULM   (Germany)

^d HANNOVER MEDICAL SCHOOL   (Germany)

^e INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

CD40 ligand deficiency; ; Hyper IgM syndrome; ; Neuroendocrine carcinoma

Indexed keywords

AMYLASE; BLEOMYCIN; CD40 LIGAND; CD56 ANTIGEN; CHROMOGRANIN A; CISPLATIN; CYCLOSPORIN; CYTOKERATIN; DACTINOMYCIN; DOXORUBICIN; ERGOCALCIFEROL; ETOPOSIDE; GEMCITABINE; IFOSFAMIDE; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IRINOTECAN; METHYLPREDNISOLONE; MYCOPHENOLIC ACID; OCTREOTIDE; OXALIPLATIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; SYNAPTOPHYSIN; VINCRISTINE;

ADOLESCENT; ALLOGENIC BONE MARROW TRANSPLANTATION; AMYLASE BLOOD LEVEL; ANTIGEN EXPRESSION; ARTICLE; BRAIN EDEMA; CANCER MORTALITY; CANCER SUSCEPTIBILITY; CARCINOMA; CAUSE OF DEATH; CHOLESTASIS; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DISEASE ASSOCIATION; HUMAN; HUMAN TISSUE; HYPER IGM SYNDROME; IMMUNE DEFICIENCY; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER FAILURE; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MALE; MULTIPLE CYCLE TREATMENT; NEUROENDOCRINE TUMOR; NEUTROPENIA; NUCLEAR MAGNETIC RESONANCE IMAGING; PERCUTANEOUS TRANSHEPATIC DRAINAGE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SCHOOL CHILD; SOLID TUMOR; X CHROMOSOME LINKED DISORDER;

ADOLESCENT; CARCINOMA, NEUROENDOCRINE; CD40 LIGAND; CHILD; DIGESTIVE SYSTEM NEOPLASMS; DNA; FATAL OUTCOME; HUMANS; HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1; IMMUNOGLOBULIN ISOTYPES; MALE;

EID: 55249111485     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2008.08.005     Document Type: Article

References (17)

1. Erdo{double acute}s M., Durandy A., and Maródi L. Genetically acquired class-switch recombination defects: the multi-faced hyper-IgM syndrome. Immunol. Lett. 97 (2005) 1-6
2. Erdo{double acute}s M., Lakos G., Dérfalvi B., Notarangelo L.D., Durandy A., and Maródi L. Molecular genetic analysis of Hungarian patients with the hyper-immunoglobulin M syndrome. Mol. Immunol. 45 (2008) 278-282
3. Notarangelo L.D., Lanzi G., Peron S., and Durandy A. Defects of class-switch recombination. J. Allergy Clin. Immunol. 117 (2006) 855-864
4. Levy J., Espanol-Boren T., Thomas C., Fischer A., Tovo P., Bordigoni P., Resnick I., Fasth A., Baer M., Gomez L., Sanders E.A., Tabobe M.D., Plantaz D., Etzioni A., Monafo V., Abinun M., Hammarstrom L., Abrahamsen T., Jones A., Finn A., Klemola T., DeVries E., Sanal O., Peitsch M.C., and Notarangelo L.D. Clinical spectrum of X-linked hyper-IgM syndrome. J. Pediatr. 131 (1997) 47-54
5. Hayward A.R., Levy J., Facchetti F., Notarangelo L.D., Ochs H.D., Etzioni A., Bonnefoy J.Y., Cosyns M., and Weinberg A. Cholangiopathy and tumors of the pancreas, liver, and biliary tree in boys with X-linked immunodeficiency with hyper-IgM. J. Immunol. 158 (1997) 977-983
6. Winkelstein J.A., Marino M.C., Ochs H., Fuleihan R., Scholl P.R., Geha R., Stiehm E.R., and Conley M.E. The X-linked hyper-IgM syndrome: clinical and immunologic features of 79 patients. Medicine (Baltimore), 82 (2003) 373-384
7. Broaddus R.R., Herzog C.E., and Hicks M.J. Neuroendocrine tumors (carcinoid and neuroendocrine carcinoma) presenting at extra-appendiceal sites in childhood and adolescence. Arch. Pathol. Lab. Med. 127 (2003) 1200-1203
8. de Bruin N.C., de Groot R., den Hollander J.C., Agoston S.I., van Dongen J.J., and Neijens H.J. Small-cell undifferentiated (neuroendocrine) carcinoma of the cecum in a child with common variable immunodeficiency. Am. J. Pediatr. Hematol. Oncol. 15 (1993) 258-261
9. Sasi O.A., Sathiapalan R., Rifai A., Tulbah A.M., Al-Mehaidib A., Kofide A., and Hugosson C. Colonic neuroendocrine carcinoma in a child. Pediatr. Radiol. 35 (2005) 339-343
10. Zirkin H.J., Levy J., and Katchko L. Small cell undifferentiated carcinoma of the colon associated with hepatocellular carcinoma in an immunodeficient patient. Hum. Pathol. 27 (1996) 992-996
11. Nagaraj N., Egwim C., and Adler D.G. X-linked hyper-IgM syndrome associated with poorly differentiated neuroendocrine tumor presenting as obstructive jaundice secondary to extensive adenopathy. Dig. Dis. Sci. 52 (2007) 2312-2316
12. Knerr V., and Grimbacher B. Primary immunodeficiency registries. Curr. Opin. Allergy Clin. Immunol. 7 (2007) 475-480
13. Brugnoni D., Airo P., Graf D., Marconi M., Lebowitz M., Plebani A., Giliani S., Malacarne F., Cattaneo R., and Ugazio A.G. Ineffective expression of CD40 ligand on cord blood T cells may contribute to poor immunoglobulin production in the newborn. Eur. J. Immunol. 24 (1994) 1919-1924
14. Al Saadi A., Palutke M., and Kumar G.K. Evolution of chromosomal abnormalities in sequential cytogenetic studies of ataxia telangiectasia. Hum. Genet. 55 (1980) 23-29
15. Sullivan K.E., Mullen C.A., Blaese R.M., and Winkelstein J.A. A multiinstitutional survey of the Wiskott-Aldrich syndrome. J. Pediatr. 125 (1994) 876-885
16. Zullo A., Romiti A., Rinaldi V., Vecchione A., Tomao S., Aiuti F., Frati L., and Luzi G. Gastric pathology in patients with common variable immunodeficiency. Gut 45 (1999) 77-81
17. Chu P.G., Arber D.A., and Weiss L.M. Expression of T/NK-cell and plasma cell antigens in nonhematopoietic epithelioid neoplasms. An immunohistochemical study of 447 cases. Am. J. Clin. Pathol. 120 (2003) 64-70