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Volumn 7, Issue 6, 2012, Pages

A transplantable phosphorylation probe for direct assessment of G protein-coupled receptor activation

Author keywords

[No Author keywords available]

Indexed keywords

DG 3173; G PROTEIN COUPLED RECEPTOR; OCTREOTIDE; PASIREOTIDE; SOMATOPRIM; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR 2; SOMATOSTATIN RECEPTOR 3; SOMATOSTATIN RECEPTOR 5; UNCLASSIFIED DRUG;

EID: 84862743119     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039458     Document Type: Article
Times cited : (11)

References (25)
  • 1
    • 29344452504 scopus 로고    scopus 로고
    • Treatment of acromegaly: future
    • Donangelo I, Melmed S, (2005) Treatment of acromegaly: future. Endocrine 28: 123-128.
    • (2005) Endocrine , vol.28 , pp. 123-128
    • Donangelo, I.1    Melmed, S.2
  • 2
    • 84925581799 scopus 로고    scopus 로고
    • Role of somatostatins in gastroenteropancreatic neuroendocrine tumor development and therapy
    • Oberg KE, Reubi JC, Kwekkeboom DJ, Krenning EP, (2010) Role of somatostatins in gastroenteropancreatic neuroendocrine tumor development and therapy. Gastroenterology 139: 742-753, 753 e741.
    • (2010) Gastroenterology , vol.139
    • Oberg, K.E.1    Reubi, J.C.2    Kwekkeboom, D.J.3    Krenning, E.P.4
  • 3
    • 0036111856 scopus 로고    scopus 로고
    • SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile
    • Bruns C, Lewis I, Briner U, Meno-Tetang G, Weckbecker G, (2002) SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile. Eur J Endocrinol 146: 707-716.
    • (2002) Eur J Endocrinol , vol.146 , pp. 707-716
    • Bruns, C.1    Lewis, I.2    Briner, U.3    Meno-Tetang, G.4    Weckbecker, G.5
  • 4
    • 0038440483 scopus 로고    scopus 로고
    • A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential
    • Lewis I, Bauer W, Albert R, Chandramouli N, Pless J, et al. (2003) A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential. J Med Chem 46: 2334-2344.
    • (2003) J Med Chem , vol.46 , pp. 2334-2344
    • Lewis, I.1    Bauer, W.2    Albert, R.3    Chandramouli, N.4    Pless, J.5
  • 5
    • 21844451422 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic comparison of a novel multiligand somatostatin analog, SOM230, with octreotide in patients with acromegaly
    • Ma P, Wang Y, van der Hoek J, Nedelman J, Schran H, et al. (2005) Pharmacokinetic-pharmacodynamic comparison of a novel multiligand somatostatin analog, SOM230, with octreotide in patients with acromegaly. Clin Pharmacol Ther 78: 69-80.
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 69-80
    • Ma, P.1    Wang, Y.2    van der Hoek, J.3    Nedelman, J.4    Schran, H.5
  • 6
    • 58149383820 scopus 로고    scopus 로고
    • Treatment of pituitary-dependent Cushing's disease with the multireceptor ligand somatostatin analog pasireotide (SOM230): a multicenter, phase II trial
    • Boscaro M, Ludlam WH, Atkinson B, Glusman JE, Petersenn S, et al. (2009) Treatment of pituitary-dependent Cushing's disease with the multireceptor ligand somatostatin analog pasireotide (SOM230): a multicenter, phase II trial. J Clin Endocrinol Metab 94: 115-122.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 115-122
    • Boscaro, M.1    Ludlam, W.H.2    Atkinson, B.3    Glusman, J.E.4    Petersenn, S.5
  • 7
    • 77956551606 scopus 로고    scopus 로고
    • Medical treatment of Cushing's disease: somatostatin analogues and pasireotide
    • Pedroncelli AM, (2010) Medical treatment of Cushing's disease: somatostatin analogues and pasireotide. Neuroendocrinology 92: 120-124.
    • (2010) Neuroendocrinology , vol.92 , pp. 120-124
    • Pedroncelli, A.M.1
  • 8
    • 77954484928 scopus 로고    scopus 로고
    • Pasireotide (SOM230) demonstrates efficacy and safety in patients with acromegaly: a randomized, multicenter, phase II trial
    • Petersenn S, Schopohl J, Barkan A, Mohideen P, Colao A, et al. (2009) Pasireotide (SOM230) demonstrates efficacy and safety in patients with acromegaly: a randomized, multicenter, phase II trial. J Clin Endocrinol Metab 95: 2781-2789.
    • (2009) J Clin Endocrinol Metab , vol.95 , pp. 2781-2789
    • Petersenn, S.1    Schopohl, J.2    Barkan, A.3    Mohideen, P.4    Colao, A.5
  • 9
    • 75149175187 scopus 로고    scopus 로고
    • Pasireotide and octreotide stimulate distinct patterns of sst2A somatostatin receptor phosphorylation
    • Poll F, Lehmann D, Illing S, Ginj M, Jacobs S, et al. (2010) Pasireotide and octreotide stimulate distinct patterns of sst2A somatostatin receptor phosphorylation. Mol Endocrinol 24: 436-446.
    • (2010) Mol Endocrinol , vol.24 , pp. 436-446
    • Poll, F.1    Lehmann, D.2    Illing, S.3    Ginj, M.4    Jacobs, S.5
  • 10
    • 57349142534 scopus 로고    scopus 로고
    • Reassessment of sst2 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-1
    • Fischer T, Doll C, Jacobs S, Kolodziej A, Stumm R, et al. (2008) Reassessment of sst2 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-1. J Clin Endocrinol Metab 93: 4519-4524.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 4519-4524
    • Fischer, T.1    Doll, C.2    Jacobs, S.3    Kolodziej, A.4    Stumm, R.5
  • 11
    • 59749083610 scopus 로고    scopus 로고
    • Differential effects of octreotide and pasireotide on somatostatin receptor internalization and trafficking in vitro
    • Lesche S, Lehmann D, Nagel F, Schmid HA, Schulz S, (2009) Differential effects of octreotide and pasireotide on somatostatin receptor internalization and trafficking in vitro. J Clin Endocrinol Metab 94: 654-661.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 654-661
    • Lesche, S.1    Lehmann, D.2    Nagel, F.3    Schmid, H.A.4    Schulz, S.5
  • 12
    • 0344442675 scopus 로고    scopus 로고
    • Somatostatin receptor subtypes in human pheochromocytoma: subcellular expression pattern and functional relevance for octreotide scintigraphy
    • Mundschenk J, Unger N, Schulz S, Hollt V, Schulz S, et al. (2003) Somatostatin receptor subtypes in human pheochromocytoma: subcellular expression pattern and functional relevance for octreotide scintigraphy. J Clin Endocrinol Metab 88: 5150-5157.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5150-5157
    • Mundschenk, J.1    Unger, N.2    Schulz, S.3    Hollt, V.4    Schulz, S.5
  • 13
    • 42049104363 scopus 로고    scopus 로고
    • Selective loss of somatostatin receptor 2 in octreotide-resistant growth hormone-secreting adenomas
    • Plockinger U, Albrecht S, Mawrin C, Saeger W, Buchfelder M, et al. (2008) Selective loss of somatostatin receptor 2 in octreotide-resistant growth hormone-secreting adenomas. J Clin Endocrinol Metab 93: 1203-1210.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 1203-1210
    • Plockinger, U.1    Albrecht, S.2    Mawrin, C.3    Saeger, W.4    Buchfelder, M.5
  • 14
    • 0034125452 scopus 로고    scopus 로고
    • Immunohistochemical determination of five somatostatin receptors in meningioma reveals frequent overexpression of somatostatin receptor subtype sst2A
    • Schulz S, Pauli SU, Schulz S, Handel M, Dietzmann K, et al. (2000) Immunohistochemical determination of five somatostatin receptors in meningioma reveals frequent overexpression of somatostatin receptor subtype sst2A. Clin Cancer Res 6: 1865-1874.
    • (2000) Clin Cancer Res , vol.6 , pp. 1865-1874
    • Schulz, S.1    Pauli, S.U.2    Schulz, S.3    Handel, M.4    Dietzmann, K.5
  • 15
    • 0035958027 scopus 로고    scopus 로고
    • Homo- and heterodimerization of somatostatin receptor subtypes. Inactivation of sst(3) receptor function by heterodimerization with sst(2A)
    • Pfeiffer M, Koch T, Schroder H, Klutzny M, Kirscht S, et al. (2001) Homo- and heterodimerization of somatostatin receptor subtypes. Inactivation of sst(3) receptor function by heterodimerization with sst(2A). J Biol Chem 276: 14027-14036.
    • (2001) J Biol Chem , vol.276 , pp. 14027-14036
    • Pfeiffer, M.1    Koch, T.2    Schroder, H.3    Klutzny, M.4    Kirscht, S.5
  • 16
    • 34447633368 scopus 로고    scopus 로고
    • Conformational complexity of G-protein-coupled receptors
    • Kobilka BK, Deupi X, (2007) Conformational complexity of G-protein-coupled receptors. Trends Pharmacol Sci 28: 397-406.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 397-406
    • Kobilka, B.K.1    Deupi, X.2
  • 17
    • 67649884461 scopus 로고    scopus 로고
    • Site specificity of agonist and second messenger-activated kinases for somatostatin receptor subtype 2A (Sst2A) phosphorylation
    • Liu Q, Bee MS, Schonbrunn A, (2009) Site specificity of agonist and second messenger-activated kinases for somatostatin receptor subtype 2A (Sst2A) phosphorylation. Mol Pharmacol 76: 68-80.
    • (2009) Mol Pharmacol , vol.76 , pp. 68-80
    • Liu, Q.1    Bee, M.S.2    Schonbrunn, A.3
  • 18
    • 66249144426 scopus 로고    scopus 로고
    • The structure and function of G-protein-coupled receptors
    • Rosenbaum DM, Rasmussen SG, Kobilka BK, (2009) The structure and function of G-protein-coupled receptors. Nature 459: 356-363.
    • (2009) Nature , vol.459 , pp. 356-363
    • Rosenbaum, D.M.1    Rasmussen, S.G.2    Kobilka, B.K.3
  • 19
    • 56649102191 scopus 로고    scopus 로고
    • Conformational changes involved in G-protein-coupled-receptor activation
    • Wess J, Han SJ, Kim SK, Jacobson KA, Li JH, (2008) Conformational changes involved in G-protein-coupled-receptor activation. Trends Pharmacol Sci 29: 616-625.
    • (2008) Trends Pharmacol Sci , vol.29 , pp. 616-625
    • Wess, J.1    Han, S.J.2    Kim, S.K.3    Jacobson, K.A.4    Li, J.H.5
  • 21
    • 79954425389 scopus 로고    scopus 로고
    • Structural insights into adrenergic receptor function and pharmacology
    • Kobilka BK, (2011) Structural insights into adrenergic receptor function and pharmacology. Trends Pharmacol Sci 32: 213-218.
    • (2011) Trends Pharmacol Sci , vol.32 , pp. 213-218
    • Kobilka, B.K.1
  • 22
    • 80051658642 scopus 로고    scopus 로고
    • Crystal structure of the beta2 adrenergic receptor-Gs protein complex
    • Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, et al. (2011) Crystal structure of the beta2 adrenergic receptor-Gs protein complex. Nature 477: 549-555.
    • (2011) Nature , vol.477 , pp. 549-555
    • Rasmussen, S.G.1    DeVree, B.T.2    Zou, Y.3    Kruse, A.C.4    Chung, K.Y.5
  • 23
    • 78149496369 scopus 로고    scopus 로고
    • Sensing G protein-coupled receptor activation
    • Ambrosio M, Zurn A, Lohse MJ, (2011) Sensing G protein-coupled receptor activation. Neuropharmacology 60: 45-51.
    • (2011) Neuropharmacology , vol.60 , pp. 45-51
    • Ambrosio, M.1    Zurn, A.2    Lohse, M.J.3
  • 24
    • 79953902541 scopus 로고    scopus 로고
    • Differential temporal and spatial regulation of somatostatin receptor phosphorylation and dephosphorylation
    • Ghosh M, Schonbrunn A, (2011) Differential temporal and spatial regulation of somatostatin receptor phosphorylation and dephosphorylation. J Biol Chem 286: 13561-13573.
    • (2011) J Biol Chem , vol.286 , pp. 13561-13573
    • Ghosh, M.1    Schonbrunn, A.2
  • 25
    • 84856094615 scopus 로고    scopus 로고
    • DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours
    • Plockinger U, Hoffmann U, Geese M, Lupp A, Buchfelder M, et al. (2012) DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours. Eur J Endocrinol 166: 223-234.
    • (2012) Eur J Endocrinol , vol.166 , pp. 223-234
    • Plockinger, U.1    Hoffmann, U.2    Geese, M.3    Lupp, A.4    Buchfelder, M.5


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