Safety evaluation of EvesseTM EPC, an apple polyphenol extract rich in flavan-3-ols

Food and Chemical Toxicology

Volumn 50, Issue 8, 2012, Pages 2845-2853

  Lina, B A R ^a   Reus, A A ^a   Hasselwander, O ^b   Bui, Q ^c   Tenning, P P ^d  

^a TNO   (Netherlands)

^b Danisco (UK) Limited   (United Kingdom)

^c GENENCOR INTERNATIONAL INC   (United States)

^d DANISCO A S   (Denmark)

Author keywords

EPC; Apple polyphenols; Epicatechin; Genotoxicity; Ninety day toxicity

Indexed keywords

APPLE EXTRACT; CREATININE; EPICATECHIN; FLAVAN 3 OL DERIVATIVE; PLANT EXTRACT; POLYPHENOL; UNCLASSIFIED DRUG;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL REVERSE MUTATION TEST; BODY WEIGHT; BONE MARROW; COMET ASSAY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; FEMALE; FLUID INTAKE; FOOD COMPOSITION; FOOD INTAKE; FOOD SAFETY; GENOTOXICITY; HISTOPATHOLOGY; HUMAN; HYPERTROPHY; IN VITRO STUDY; IN VIVO STUDY; INTESTINE CELL; KIDNEY; LIVER; LIVER CELL; MALE; MICRONUCLEUS TEST; MOUSE LYMPHOMA ASSAY; NONHUMAN; ORGAN WEIGHT; PAROTID GLAND; PROTHROMBIN TIME; RAT; SEX DIFFERENCE; SPLEEN; THROMBOCYTE; TOXICITY TESTING;

ANIMALS; FEMALE; FLAVONOIDS; MALE; MALUS; MICE; MICRONUCLEUS TESTS; PLANT EXTRACTS; POLYPHENOLS; RATS; RATS, WISTAR;

BACTERIA (MICROORGANISMS); MALUS X DOMESTICA; RATTUS;

EID: 84862670474     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.05.013     Document Type: Article

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