Involvement of hydrogen peroxide in chromosomal aberrations induced by green tea catechins in vitro and implications for risk assessment

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 657, Issue 1, 2008, Pages 13-18

  Takumi Kobayashi, Asuka ^a   Ogura, Ryosuke ^a   Morita, Osamu ^a   Nishiyama, Naohiro ^a   Kasamatsu, Toshio ^a  

^a KAO CORPORATION   (Japan)

Author keywords

Catechin; Chromosomal aberration; Genotoxicity; Hydrogen peroxide

Indexed keywords

CATALASE; CATECHIN; HYDROGEN PEROXIDE; POLYPHENOL; WATER;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BEVERAGE; CHROMOSOME ABERRATION; CONTROLLED STUDY; GENOTOXICITY; IN VITRO STUDY; NONHUMAN; PH; PRIORITY JOURNAL; RISK ASSESSMENT; TEA;

ANIMALS; CATALASE; CATECHIN; CELL LINE; CHROMOSOME ABERRATIONS; CRICETINAE; CRICETULUS; HYDROGEN PEROXIDE; REACTIVE OXYGEN SPECIES; RISK ASSESSMENT; TEA;

EID: 56349117929     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2008.08.016     Document Type: Article

References (40)

1. Katiyar S.K., and Mukhtar H. Tea antioxidants in cancer chemoprevention. J. Cell Biochem. Suppl. 27 (1997) 59-67
2. Murase T., Nagasawa A., Suzuki J., Hase T., and Tokimitsu I. Beneficial effects of tea catechins on diet-induced obesity: stimulation of lipid catabolism in the liver. Int. J. Obes. 26 (2002) 1459-1464
3. Nagao T., Komine Y., Soga S., Meguro S., Hase T., Tanaka Y., and Tokimitsu I. Ingestion of a tea rich in catechins leads a reduction in body fat and malondialehyde-modified LDL in men. Am. J. Clin. Nutr. 81 (2005) 122-129
4. Song J.M., Lee K.H., and Seong B.L. Antiviral effect of catechins in green tea on influenza virus. Antivir. Res. 68 (2005) 66-74
5. Ikeda I., Tsuda K., Suzuki Y., Kobayashi M., Unno T., Tomoyori H., Goto H., Kawata Y., Imaizumi K., Nozawa A., and Kakuda T. Tea catechins with a galloyl moiety suppress postprandial hypertriacylglycerolemia by delaying lymphatic transport of dietary fat in rats. J. Nutr. 135 (2005) 155-159
6. Lee A.H., Fraser M.L., Meng X., and Binns C.W. Protective effects of green tea against prostate cancer. Expert Rev. Anticancer Ther. 6 (2006) 507-513
7. Bemis D.L., Katz A.E., and Buttyan R. Clinical trials of natural products as chemopreventive agents for prostate cancer. Expert Opin. Investig. Drugs 15 (2006) 1191-1200
8. Yuan J.M., Gao Y.T., Yang C.S., and Yu M.C. Urinary biomarkers of tea polyphenols and risk of colorectal cancer in the Shanghai Cohort Study. Int. J. Cancer 120 (2007) 1344-1350
9. Wolfam S. Effects of green tea and EGCG on cardiovascular and metabolic health. J. Am. Coll. Nutr. 26 (2007) 373S-388S
10. Igarashi K., Honma K., Yoshinari O., Nanjo F., and Hara Y. Effects of dietary catechins on glucose tolerance, blood pressure and oxidative status in Goto-Kakizaki rats. J. Nutr. Sci. Vitaminol. 53 (2007) 496-500
11. Kurahashi N., Sasazuki S., Iwasaki M., Inoue M., and Tsugane S. Green tea consumption and prostate cancer risk in Japanese men: a prospective study. Am. J. Epidemiol. 167 (2008) 71-77
12. Inagake M., Yamane T., Kitao Y., Oya K., Matsumoto H., Kikuoka N., Nakatani H., Takahashi T., Nishimura H., and Iwashima A. Inhibition of 1,2-dimethylhydrazine-induced oxidative DNA damage by green tea extract in rat. Jpn. J. Cancer Res. 86 (1995) 1106-1111
13. Muto S., Yokoi T., Gondo Y., Katsuki M., Shioyama Y., Fujita K., and Kamataki T. Inhibition of benzo[a]pyrene-induced mutagenesis by (-)-epigallocatechin gallate in the lung of rpsL transgenic mice. Carcinogenesis 20 (1999) 421-424
14. Hour T.C., Liang Y.C., Chu I.S., and Lin J.K. Inhibition of eleven mutagens by various tea extracts, (-)-epigallocatechin-3-gallate, gallic acid and caffeine. Food Chem. Toxicol. 37 (1999) 569-579
15. Johnson M.K., and Loo G. Effects of epigallocatechin gallate and quercetin on oxidative damage to cellular DNA. Mutat. Res. 459 (2000) 211-218
16. Sugisawa A., and Umegaki K. Physiological concentrations of (-)-epigallocatechin-3-o-gallate (EGCg) prevent chromosomal damage induced by reactive oxygen species. J. Nutr. 132 (2002) 1836-1839
17. Arimoto-Kobayashi S., Inada N., Sato Y., Sugiyama C., Okamoto K., Hayatsu H., and Negishi T. Inhibitory effects of (-)-epigallocatechin gallate on the mutation, DNA strand cleavage, and DNA adduct formation by heterocyclic amines. J. Agric. Food Chem. 51 (2003) 5150-5153
18. Iwai K., Iwamura Y., Yamashita S., Wadano Y., and Mesaki N. Effect of tea catechins on mitochondrial DNA 4977-bp deletions in human leucocytes. Mutat. Res. 595 (2005) 191-195
19. Oikawa S., Furukawa A., Asada H., Hirakawa K., and Kawanishi S. Catechins induce oxidative damage to cellular and isolated DNA through the generation of reactive oxygen species. Free Radical Res. 37 (2003) 881-890
20. Elbling L., Weiss R.M., Teufelhofer O., Uhl M., Knasmueller S., Hermann R.S., Berger W., and Micksche M. Green tea extract and (-)-epigallocatechin-3-gallate, the major tea catechin, exert oxidant but lack antioxidant activities. FASEB J. 19 (2005) 807-809
21. Ogura R., Ikeda N., Yuki K., Morita O., Saigo K., Blackstock C., Nishimura N., and Kasamatsu T. Genotoxicity studies on green tea catechin. Food Chem. Toxicol. 46 (2008) 2190-2200
22. Chang P.Y., Mirsalis J., Riccio E.S., Bakke J.P., Lee P.S., Shimon J., Phillips S., Fairchild D., Hara Y., and Crowell J.A. Genotoxicity and toxicity of the potential cancer-preventive agent Polyphenon E. Environ. Mol. Mutagen. 41 (2003) 43-54
23. Isbrucker R.A., Bausch J., Edwards J.A., and Wolz E. Safety studies on epigallocatechin gallate (EGCG) preparations. Part 1: genotoxicity. Food Chem. Toxicol. 44 (2006) 626-635
24. The Japanese Pharmacopoeia 15th ed., Hirokawa Publishing Co., Tokyo, 2006, B1039.
25. The Japanese Pharmacopoeia 15th ed., Hirokawa Publishing Co., Tokyo, 2006, B1012.
26. Tilly J.L., and Tilly K.I. Inhibitors of oxidative stress mimic the ability of follicle-stimulating hormone to suppress apoptosis in cultured rat ovarian follicles. Endocrinology 136 (2006) 242-252
27. Tayama S., and Nakagawa Y. Effect of scavengers of active oxygen species on cell damage caused in CHO-K1 cells by phenylhydroquinone, an o-phenylphenol metabolite. Mutat. Res. 324 (1994) 121-131
28. Oya Y., Yamamoto K., and Tonomura A. The biological activity of hydrogen peroxide I. Induction of chromosome-type aberrations susceptible to inhibition by scavengers of hydroxyl radicals in human embryonic fibroblasts. Mutat. Res. 172 (1986) 245-253
29. Long L.H., Clement M.V., and Halliwell B. Artifacts in cell culture: rapid generation of hydrogen peroxide on addition of (-)-epigallocatechin, (-)-epigallocatechin gallate, (+)-catechin, and quercetin to commonly used cell culture media. Biochem. Biophys. Res. Commun. 273 (2000) 50-53
30. Long L.H., Kirkland D., Whitwell J., and Halliwell B. Different cytotoxic and clastogenic effects of epigallocatechin gallate in various cell-culture media due to variable rates of its oxidation in the culture medium. Mutat. Res. 634 (2007) 177-183
31. Nakayama T., Ichiba M., Kuwabara M., Kajita K., and Kumazawa S. Mechanisms and structural specificity of hydrogen peroxide formation during oxidation of catechins. Food Sci. Technol. Res. 8 (2002) 261-267
32. Arakawa H., Maeda M., Okubo S., and Shimamura T. Role of hydrogen peroxide in bactericidal action of catechin. Biol. Pharm. Bull. 27 (2004) 277-281
33. Akagawa M., Shigemitsu T., and Suyama K. Production of hydrogen peroxide by polyphenols and polyphenol-rich beverage under quasi-physiological conditions. Biosci. Biotechnol. Biochem. 67 (2003) 2632-2640
34. Chow H.-H.S., Cai Y., Alberts D.S., Hakim I., Dorr R., Shahi F., Crowell J.A., Yang C.S., and Hara Y. Phase I pharmacokinetics study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E. Cancer Epidemiol. Biomarkers 10 (2001) 53-58
35. Masukawa Y., Matsui Y., Shimizu N., Kondou N., Endou H., Kuzukawa M., and Hase T. Determination of green tea catechins in human plasma using liquid chromatography-electrospray ionization mass spectrometry. J. Chromatogr. B 834 (2006) 26-34
36. Dresso J.M., Lavin A.L., Hsia S.M., and Mavis R.D. Assessment of the carcinogenicity associated with oral exposures to hydrogen peroxide. Food Chem. Toxicol. 38 (2000) 1021-1041
37. SCCNFP/0602/02, Opinion of the scientific committee on cosmetic products and non-food products intended for consumers concerning hydrogen (carbamide, zinc) peroxide in tooth bleaching whitening products, 2002.
38. Sullivan M., Galea P., and Latif S. Letter to the Editor; what is the appropriate oxygen tension for in vitro culture?. Mol. Hum. Reprod. 12 (2006) 653
39. Sang S., Hou Z., Lambert J.D., and Yang C.S. Redox properties of tea polyphenols and related biological activities. Antioxid. Redox Signal. 7 (2005) 1704-1714
40. Kirkland D.J., Aardema M., Banduhn N., Carmicheal P., Fautz R., Meunier J.-R., and Pfuhle S. In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results. Mutagenesis (2007) 1-15