-
1
-
-
79959808736
-
Animal models for arthritis: Innovative tools for prevention and treatment
-
Kollias G, Papadaki P, Apparailly F, Vervoordeldonk MJ, Holmdahl R, Baumans V, Desaintes C, Di Santo J, Distler J, Garside P, Hegen M, Huizinga TW, Jungel A, Klareskog L, McInnes I, Ragoussis I, Schett G, Hart BT, Tak PP, Toes R, van den Berg W, Wurst W, Gay S: Animal models for arthritis: innovative tools for prevention and treatment. Ann Rheum Dis 2011, 70:1357-1362
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1357-1362
-
-
Kollias, G.1
Papadaki, P.2
Apparailly, F.3
Vervoordeldonk, M.J.4
Holmdahl, R.5
Baumans, V.6
Desaintes, C.7
Di Santo, J.8
Distler, J.9
Garside, P.10
Hegen, M.11
Huizinga, T.W.12
Jungel, A.13
Klareskog, L.14
McInnes, I.15
Ragoussis, I.16
Schett, G.17
Hart, B.T.18
Tak, P.P.19
Toes, R.20
Van Den Berg, W.21
Wurst, W.22
Gay, S.23
more..
-
2
-
-
24344440857
-
Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis
-
Nandakumar KS, Holmdahl R: Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis. J Immunol Methods 2005, 304:126-136
-
(2005)
J Immunol Methods
, vol.304
, pp. 126-136
-
-
Nandakumar, K.S.1
Holmdahl, R.2
-
4
-
-
17444405097
-
Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells
-
Nandakumar KS, Backlund J, Vestberg M, Holmdahl R: Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells. Arthritis Res Ther 2004, 6:R544-R550
-
(2004)
Arthritis Res Ther
, vol.6
-
-
Nandakumar, K.S.1
Backlund, J.2
Vestberg, M.3
Holmdahl, R.4
-
5
-
-
77955452602
-
Rabeximod reduces arthritis severity in mice by decreasing activation of inflammatory cells
-
Hultqvist M, Nandakumar KS, Bjorklund U, Holmdahl R: Rabeximod reduces arthritis severity in mice by decreasing activation of inflammatory cells. Ann Rheum Dis 2010, 69:1527-1532
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 1527-1532
-
-
Hultqvist, M.1
Nandakumar, K.S.2
Bjorklund, U.3
Holmdahl, R.4
-
6
-
-
77956995291
-
Urokinase-type plasminogen activator and arthritis progression: Role in systemic disease with immune complex involvement
-
Cook AD, De Nardo CM, Braine EL, Turner AL, Vlahos R, Way KJ, Beckman SK, Lenzo JC, Hamilton JA: Urokinase-type plasminogen activator and arthritis progression: role in systemic disease with immune complex involvement. Arthritis Res Ther 2010, 12:R37
-
(2010)
Arthritis Res Ther
, vol.12
-
-
Cook, A.D.1
De Nardo, C.M.2
Braine, E.L.3
Turner, A.L.4
Vlahos, R.5
Way, K.J.6
Beckman, S.K.7
Lenzo, J.C.8
Hamilton, J.A.9
-
7
-
-
38149048556
-
Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis
-
Abdollahi-Roodsaz S, Joosten LA, Koenders MI, Devesa I, Roelofs MF, Radstake TR, Heuvelmans-Jacobs M, Akira S, Nicklin MJ, Ribeiro-Dias F, van den Berg WB: Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis. J Clin Invest 2008, 118:205-216
-
(2008)
J Clin Invest
, vol.118
, pp. 205-216
-
-
Abdollahi-Roodsaz, S.1
Joosten, L.A.2
Koenders, M.I.3
Devesa, I.4
Roelofs, M.F.5
Radstake, T.R.6
Heuvelmans-Jacobs, M.7
Akira, S.8
Nicklin, M.J.9
Ribeiro-Dias, F.10
Van Den Berg, W.B.11
-
8
-
-
79951854918
-
Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures
-
Nic An Ultaigh S, Saber TP, McCormick J, Connolly M, Dellacasagrande J, Keogh B, McCormack W, Reilly M, O'Neill LA, McGuirk P, Fearon U, Veale DJ: Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures. Arthritis Res Ther 2011, 13:R33
-
(2011)
Arthritis Res Ther
, vol.13
-
-
Nic An Ultaigh, S.1
Saber, T.P.2
McCormick, J.3
Connolly, M.4
Dellacasagrande, J.5
Keogh, B.6
McCormack, W.7
Reilly, M.8
O'Neill, L.A.9
McGuirk, P.10
Fearon, U.11
Veale, D.J.12
-
9
-
-
77952483341
-
Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats
-
Meng L, Zhu W, Jiang C, He X, Hou W, Zheng F, Holmdahl R, Lu S: Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats. Arthritis Res Ther 2010, 12:R103
-
(2010)
Arthritis Res Ther
, vol.12
-
-
Meng, L.1
Zhu, W.2
Jiang, C.3
He, X.4
Hou, W.5
Zheng, F.6
Holmdahl, R.7
Lu, S.8
-
10
-
-
33846922783
-
Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs
-
Yarilina A, DiCarlo E, Ivashkiv LB: Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs. J Immunol 2007, 178:2204-2211
-
(2007)
J Immunol
, vol.178
, pp. 2204-2211
-
-
Yarilina, A.1
DiCarlo, E.2
Ivashkiv, L.B.3
-
11
-
-
57349192121
-
Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: Toll-like receptor expression in early and longstanding arthritis
-
Ospelt C, Brentano F, Rengel Y, Stanczyk J, Kolling C, Tak PP, Gay RE, Gay S, Kyburz D: Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: toll-like receptor expression in early and longstanding arthritis. Arthritis Rheum 2008, 58:3684-3692
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3684-3692
-
-
Ospelt, C.1
Brentano, F.2
Rengel, Y.3
Stanczyk, J.4
Kolling, C.5
Tak, P.P.6
Gay, R.E.7
Gay, S.8
Kyburz, D.9
-
12
-
-
67349111091
-
Synergism of toll-like receptor 2 (TLR2). TLR4, and TLR6 ligation on the production of tumor necrosis factor (TNF)-alpha in a spontaneous arthritis animal model of interleukin (IL)-1 receptor antagonist-deficient mice
-
Jung YO, Cho ML, Lee SY, Oh HJ, Park JS, Park MK, Park MJ, Ju JH, Kim SI, Park SH, Kim HY, Min JK: Synergism of toll-like receptor 2 (TLR2). TLR4, and TLR6 ligation on the production of tumor necrosis factor (TNF)-alpha in a spontaneous arthritis animal model of interleukin (IL)-1 receptor antagonist-deficient mice. Immunol Lett 2009, 123:138-143
-
(2009)
Immunol Lett
, vol.123
, pp. 138-143
-
-
Jung, Y.O.1
Cho, M.L.2
Lee, S.Y.3
Oh, H.J.4
Park, J.S.5
Park, M.K.6
Park, M.J.7
Ju, J.H.8
Kim, S.I.9
Park, S.H.10
Kim, H.Y.11
Min, J.K.12
-
13
-
-
69949140663
-
Type I interferons might form the link between Toll-like receptor (TLR) 3/7 and TLR4-mediated synovial inflammation in rheumatoid arthritis (RA)
-
Roelofs MF, Wenink MH, Brentano F, Abdollahi-Roodsaz S, Oppers-Walgreen B, Barrera P, van Riel PL, Joosten LA, Kyburz D, van den Berg WB, Radstake TR: Type I interferons might form the link between Toll-like receptor (TLR) 3/7 and TLR4-mediated synovial inflammation in rheumatoid arthritis (RA). Ann Rheum Dis 2009, 68:1486-1493
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1486-1493
-
-
Roelofs, M.F.1
Wenink, M.H.2
Brentano, F.3
Abdollahi-Roodsaz, S.4
Oppers-Walgreen, B.5
Barrera, P.6
Van Riel, P.L.7
Joosten, L.A.8
Kyburz, D.9
Van Den Berg, W.B.10
Radstake, T.R.11
-
14
-
-
62449295455
-
Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7
-
Hayashi T, Gray CS, Chan M, Tawatao RI, Ronacher L, McGargill MA, Datta SK, Carson DA, Corr M: Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7. Proc Natl Acad Sci U S A 2009, 106:2764-2769
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 2764-2769
-
-
Hayashi, T.1
Gray, C.S.2
Chan, M.3
Tawatao, R.I.4
Ronacher, L.5
McGargill, M.A.6
Datta, S.K.7
Carson, D.A.8
Corr, M.9
-
15
-
-
71849117626
-
Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures
-
Sacre SM, Lo A, Gregory B, Simmonds RE, Williams L, Feldmann M, Brennan FM, Foxwell BM: Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures. J Immunol 2008, 181:8002-8009
-
(2008)
J Immunol
, vol.181
, pp. 8002-8009
-
-
Sacre, S.M.1
Lo, A.2
Gregory, B.3
Simmonds, R.E.4
Williams, L.5
Feldmann, M.6
Brennan, F.M.7
Foxwell, B.M.8
-
16
-
-
38849127573
-
Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis
-
Asagiri M, Hirai T, Kunigami T, Kamano S, Gober HJ, Okamoto K, Nishikawa K, Latz E, Golenbock DT, Aoki K, Ohya K, Imai Y, Morishita Y, Miyazono K, Kato S, Saftig P, Takayanagi H: Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. Science 2008, 319:624-627
-
(2008)
Science
, vol.319
, pp. 624-627
-
-
Asagiri, M.1
Hirai, T.2
Kunigami, T.3
Kamano, S.4
Gober, H.J.5
Okamoto, K.6
Nishikawa, K.7
Latz, E.8
Golenbock, D.T.9
Aoki, K.10
Ohya, K.11
Imai, Y.12
Morishita, Y.13
Miyazono, K.14
Kato, S.15
Saftig, P.16
Takayanagi, H.17
-
17
-
-
0021998443
-
Acute joint inflammation in mice after systemic injection of the cell wall, its peptidoglycan, and chemically defined peptidoglycan subunits from various bacteria
-
Koga T, Kakimoto K, Hirofuji T, Kotani S, Ohkuni H, Watanabe K, Okada N, Okada H, Sumiyoshi A, Saisho K: Acute joint inflammation in mice after systemic injection of the cell wall, its peptidoglycan, and chemically defined peptidoglycan subunits from various bacteria. Infect Immun 1985, 50:27-34
-
(1985)
Infect Immun
, vol.50
, pp. 27-34
-
-
Koga, T.1
Kakimoto, K.2
Hirofuji, T.3
Kotani, S.4
Ohkuni, H.5
Watanabe, K.6
Okada, N.7
Okada, H.8
Sumiyoshi, A.9
Saisho, K.10
-
18
-
-
20244373339
-
A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice
-
Yoshitomi H, Sakaguchi N, Kobayashi K, Brown GD, Tagami T, Sakihama T, Hirota K, Tanaka S, Nomura T, Miki I, Gordon S, Akira S, Nakamura T, Sakaguchi S: A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice. J Exp Med 2005, 201:949-960
-
(2005)
J Exp Med
, vol.201
, pp. 949-960
-
-
Yoshitomi, H.1
Sakaguchi, N.2
Kobayashi, K.3
Brown, G.D.4
Tagami, T.5
Sakihama, T.6
Hirota, K.7
Tanaka, S.8
Nomura, T.9
Miki, I.10
Gordon, S.11
Akira, S.12
Nakamura, T.13
Sakaguchi, S.14
-
19
-
-
80051666900
-
Dectin-1 and NOD2 mediate cathepsin activation in zymosan-induced arthritis in mice
-
Rosenzweig HL, Clowers JS, Nunez G, Rosenbaum JT, Davey MP: Dectin-1 and NOD2 mediate cathepsin activation in zymosan-induced arthritis in mice. Inflamm Res 2011, 60:705-714
-
(2011)
Inflamm Res
, vol.60
, pp. 705-714
-
-
Rosenzweig, H.L.1
Clowers, J.S.2
Nunez, G.3
Rosenbaum, J.T.4
Davey, M.P.5
-
20
-
-
14944385620
-
Essential roles of Toll-like receptor-4 signaling in arthritis induced by type II collagen antibody and LPS
-
Lee EK, Kang SM, Paik DJ, Kim JM, Youn J: Essential roles of Toll-like receptor-4 signaling in arthritis induced by type II collagen antibody and LPS. Int Immunol 2005, 17:325-333
-
(2005)
Int Immunol
, vol.17
, pp. 325-333
-
-
Lee, E.K.1
Kang, S.M.2
Paik, D.J.3
Kim, J.M.4
Youn, J.5
-
21
-
-
0037224772
-
Positional identification of Ncf1 as a gene that regulates arthritis severity in rats
-
Olofsson P, Holmberg J, Tordsson J, Lu S, Akerstrom B, Holmdahl R: Positional identification of Ncf1 as a gene that regulates arthritis severity in rats. Nat Genet 2003, 33:25-32
-
(2003)
Nat Genet
, vol.33
, pp. 25-32
-
-
Olofsson, P.1
Holmberg, J.2
Tordsson, J.3
Lu, S.4
Akerstrom, B.5
Holmdahl, R.6
-
22
-
-
4344591766
-
Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene
-
Hultqvist M, Olofsson P, Holmberg J, Backstrom BT, Tordsson J, Holmdahl R: Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene. Proc Natl Acad Sci U S A 2004, 101:12646-12651
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 12646-12651
-
-
Hultqvist, M.1
Olofsson, P.2
Holmberg, J.3
Backstrom, B.T.4
Tordsson, J.5
Holmdahl, R.6
-
23
-
-
70249106454
-
Ncf1-associated reduced oxidative burst promotes IL-33R+ T cell-mediated adjuvant-free arthritis in mice
-
Hagenow K, Gelderman KA, Hultqvist M, Merky P, Backlund J, Frey O, Kamradt T, Holmdahl R: Ncf1-associated reduced oxidative burst promotes IL-33R+ T cell-mediated adjuvant-free arthritis in mice. J Immunol 2009, 183:874-881
-
(2009)
J Immunol
, vol.183
, pp. 874-881
-
-
Hagenow, K.1
Gelderman, K.A.2
Hultqvist, M.3
Merky, P.4
Backlund, J.5
Frey, O.6
Kamradt, T.7
Holmdahl, R.8
-
24
-
-
0022907908
-
High antibody response to autologous type II collagen is restricted to H-2q
-
Holmdahl R, Klareskog L, Andersson M, Hansen C: High antibody response to autologous type II collagen is restricted to H-2q. Immunogenetics 1986, 24:84-89
-
(1986)
Immunogenetics
, vol.24
, pp. 84-89
-
-
Holmdahl, R.1
Klareskog, L.2
Andersson, M.3
Hansen, C.4
-
25
-
-
34948814168
-
Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species
-
Gelderman KA, Hultqvist M, Pizzolla A, Zhao M, Nandakumar KS, Mattsson R, Holmdahl R: Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species. J Clin Invest 2007, 117:3020-3028
-
(2007)
J Clin Invest
, vol.117
, pp. 3020-3028
-
-
Gelderman, K.A.1
Hultqvist, M.2
Pizzolla, A.3
Zhao, M.4
Nandakumar, K.S.5
Mattsson, R.6
Holmdahl, R.7
-
26
-
-
0018204171
-
Genetic basis for unresponsiveness to lipopolysaccharide in C57BL/10Cr mice
-
Coutinho A, Meo T: Genetic basis for unresponsiveness to lipopolysaccharide in C57BL/10Cr mice. Immunogenetics 1978, 7:17-24
-
(1978)
Immunogenetics
, vol.7
, pp. 17-24
-
-
Coutinho, A.1
Meo, T.2
-
27
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, Du X, Birdwell D, Alejos E, Silva M, Galanos C, Freudenberg M, Ricciardi-Castagnoli P, Layton B, Beutler B: Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998, 282:2085-2088
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
Freudenberg, M.11
Ricciardi-Castagnoli, P.12
Layton, B.13
Beutler, B.14
-
29
-
-
0022656277
-
Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal anti-type II collagen antibodies
-
Holmdahl R, Rubin K, Klareskog L, Larsson E, Wigzell H: Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal anti-type II collagen antibodies. Arthritis Rheum 1986, 29:400-410
-
(1986)
Arthritis Rheum
, vol.29
, pp. 400-410
-
-
Holmdahl, R.1
Rubin, K.2
Klareskog, L.3
Larsson, E.4
Wigzell, H.5
-
30
-
-
0031915947
-
Arthritis-related B cell epitopes in collagen II are conformation- dependent and sterically privileged in accessible sites of cartilage collagen fibrils
-
Schulte S, Unger C, Mo JA, Wendler O, Bauer E, Frischholz S, von der Mark K, Kalden JR, Holmdahl R, Burkhardt H: Arthritis-related B cell epitopes in collagen II are conformation-dependent and sterically privileged in accessible sites of cartilage collagen fibrils. J Biol Chem 1998, 273:1551-1561
-
(1998)
J Biol Chem
, vol.273
, pp. 1551-1561
-
-
Schulte, S.1
Unger, C.2
Mo, J.A.3
Wendler, O.4
Bauer, E.5
Frischholz, S.6
Von Der Mark, K.7
Kalden, J.R.8
Holmdahl, R.9
Burkhardt, H.10
-
31
-
-
33645736561
-
Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen
-
Bajtner E, Nandakumar KS, Engstrom A, Holmdahl R: Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen. Arthritis Res Ther 2005, 7:R1148-R1157
-
(2005)
Arthritis Res Ther
, vol.7
-
-
Bajtner, E.1
Nandakumar, K.S.2
Engstrom, A.3
Holmdahl, R.4
-
32
-
-
0016427918
-
Nature of the collagen synthesized by a transplanted chondrosarcoma
-
Smith BD, Martin GR, Miller EJ, Dorfman A, Swarm R: Nature of the collagen synthesized by a transplanted chondrosarcoma. Arch Biochem Biophys 1975, 166:181-186
-
(1975)
Arch Biochem Biophys
, vol.166
, pp. 181-186
-
-
Smith, B.D.1
Martin, G.R.2
Miller, E.J.3
Dorfman, A.4
Swarm, R.5
-
33
-
-
0001202602
-
Genetic analysis of mouse models for rheumatoid arthritis
-
Edited by Adolph KW. New York, CRC
-
Holmdahl R, Carlsen S, Mikulowska A, Vestberg M, Brunsberg U, Hansson AS, Sundvall M, Jansson L, Pettersson U: Genetic analysis of mouse models for rheumatoid arthritis. Human Genome Methods. Edited by Adolph KW. New York, CRC, 1998, pp. 215-238
-
(1998)
Human Genome Methods
, pp. 215-238
-
-
Holmdahl, R.1
Carlsen, S.2
Mikulowska, A.3
Vestberg, M.4
Brunsberg, U.5
Hansson, A.S.6
Sundvall, M.7
Jansson, L.8
Pettersson, U.9
-
34
-
-
68549128495
-
In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012
-
Kielland A, Blom T, Nandakumar KS, Holmdahl R, Blomhoff R, Carlsen H: In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic Biol Med 2009, 47:760-766
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 760-766
-
-
Kielland, A.1
Blom, T.2
Nandakumar, K.S.3
Holmdahl, R.4
Blomhoff, R.5
Carlsen, H.6
-
35
-
-
0034063410
-
The role of lipopolysaccharide injected systemically in the reactivation of collagen-induced arthritis in mice
-
Yoshino S, Ohsawa M: The role of lipopolysaccharide injected systemically in the reactivation of collagen-induced arthritis in mice. Br J Pharmacol 2000, 129:1309-1314
-
(2000)
Br J Pharmacol
, vol.129
, pp. 1309-1314
-
-
Yoshino, S.1
Ohsawa, M.2
-
36
-
-
1642375617
-
Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent- negative regulation of proinflammatory cytokines by mycobacterial lipomannans
-
Quesniaux VJ, Nicolle DM, Torres D, Kremer L, Guerardel Y, Nigou J, Puzo G, Erard F, Ryffel B: Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans. J Immunol 2004, 172:4425-4434
-
(2004)
J Immunol
, vol.172
, pp. 4425-4434
-
-
Quesniaux, V.J.1
Nicolle, D.M.2
Torres, D.3
Kremer, L.4
Guerardel, Y.5
Nigou, J.6
Puzo, G.7
Erard, F.8
Ryffel, B.9
-
37
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA: Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 2008, 453:1122-1126
-
(2008)
Nature
, vol.453
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor, W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
38
-
-
57349165831
-
Shift from toll-like receptor 2 (TLR-2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production
-
Abdollahi-Roodsaz S, Joosten LA, Helsen MM, Walgreen B, van Lent PL, van den Bersselaar LA, Koenders MI, van den Berg WB: Shift from toll-like receptor 2 (TLR-2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production. Arthritis Rheum 2008, 58:3753-3764
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3753-3764
-
-
Abdollahi-Roodsaz, S.1
Joosten, L.A.2
Helsen, M.M.3
Walgreen, B.4
Van Lent, P.L.5
Van Den Bersselaar, L.A.6
Koenders, M.I.7
Van Den Berg, W.B.8
-
39
-
-
80051728761
-
Toll-like receptor 2 induced angiogenesis and invasion is mediated through the Tie2 signalling pathway in rheumatoid arthritis
-
Saber T, Veale DJ, Balogh E, McCormick J, Nicanultaigh S, Connolly M, Fearon U: Toll-like receptor 2 induced angiogenesis and invasion is mediated through the Tie2 signalling pathway in rheumatoid arthritis. PLoS One 2011, 6:e23540
-
(2011)
PLoS One
, vol.6
-
-
Saber, T.1
Veale, D.J.2
Balogh, E.3
McCormick, J.4
Nicanultaigh, S.5
Connolly, M.6
Fearon, U.7
-
40
-
-
84862985065
-
Induction of toll-like receptor 2 positive antigen-presenting cells in spleen of pristane-induced arthritis in rats
-
Zhu W, Meng L, Jiang C, Hou W, Xu J, Wang B, Lu S: Induction of toll-like receptor 2 positive antigen-presenting cells in spleen of pristane-induced arthritis in rats. Mol Biol Rep 2011, 39:3667-3673
-
(2011)
Mol Biol Rep
, vol.39
, pp. 3667-3673
-
-
Zhu, W.1
Meng, L.2
Jiang, C.3
Hou, W.4
Xu, J.5
Wang, B.6
Lu, S.7
-
41
-
-
1842588685
-
Mycobacterium tuberculosis lipomannan induces apoptosis and interleukin-12 production in macrophages
-
Dao DN, Kremer L, Guerardel Y, Molano A, Jacobs WR Jr., Porcelli SA, Briken V: Mycobacterium tuberculosis lipomannan induces apoptosis and interleukin-12 production in macrophages. Infect Immun 2004, 72:2067-2074
-
(2004)
Infect Immun
, vol.72
, pp. 2067-2074
-
-
Dao, D.N.1
Kremer, L.2
Guerardel, Y.3
Molano, A.4
Jacobs Jr., W.R.5
Porcelli, S.A.6
Briken, V.7
-
42
-
-
65349111937
-
TLR2-dependent eosinophil interactions with mycobacteria: Role of alpha-defensins
-
Driss V, Legrand F, Hermann E, Loiseau S, Guerardel Y, Kremer L, Adam E, Woerly G, Dombrowicz D, Capron M: TLR2-dependent eosinophil interactions with mycobacteria: role of alpha-defensins. Blood 2009, 113:3235-3244
-
(2009)
Blood
, vol.113
, pp. 3235-3244
-
-
Driss, V.1
Legrand, F.2
Hermann, E.3
Loiseau, S.4
Guerardel, Y.5
Kremer, L.6
Adam, E.7
Woerly, G.8
Dombrowicz, D.9
Capron, M.10
-
43
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
-
Ozinsky A, Underhill DM, Fontenot JD, Hajjar AM, Smith KD, Wilson CB, Schroeder L, Aderem A: The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci U S A 2000, 97:13766-13771
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 13766-13771
-
-
Ozinsky, A.1
Underhill, D.M.2
Fontenot, J.D.3
Hajjar, A.M.4
Smith, K.D.5
Wilson, C.B.6
Schroeder, L.7
Aderem, A.8
-
44
-
-
25444493823
-
Mycobacterial lipomannan induces matrix metalloproteinase-9 expression in human macrophagic cells through a Toll-like receptor 1 (TLR1)/TLR2- And CD14-dependent mechanism
-
Elass E, Aubry L, Masson M, Denys A, Guerardel Y, Maes E, Legrand D, Mazurier J, Kremer L: Mycobacterial lipomannan induces matrix metalloproteinase-9 expression in human macrophagic cells through a Toll-like receptor 1 (TLR1)/TLR2- and CD14-dependent mechanism. Infect Immun 2005, 73:7064-7068
-
(2005)
Infect Immun
, vol.73
, pp. 7064-7068
-
-
Elass, E.1
Aubry, L.2
Masson, M.3
Denys, A.4
Guerardel, Y.5
Maes, E.6
Legrand, D.7
Mazurier, J.8
Kremer, L.9
-
45
-
-
80054751966
-
Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2
-
Kadl A, Sharma PR, Chen W, Agrawal R, Meher AK, Rudraiah S, Grubbs N, Sharma R, Leitinger N: Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2. Free Radic Biol Med 2011, 51:1903-1909
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 1903-1909
-
-
Kadl, A.1
Sharma, P.R.2
Chen, W.3
Agrawal, R.4
Meher, A.K.5
Rudraiah, S.6
Grubbs, N.7
Sharma, R.8
Leitinger, N.9
-
46
-
-
65449128448
-
NADPH oxidase 2 interaction with TLR2 is required for efficient innate immune responses to mycobacteria via cathelicidin expression
-
Yang C, Shin D, Kim K, Lee Z, Lee C, Park SG, Bae YS, Jo E: NADPH oxidase 2 interaction with TLR2 is required for efficient innate immune responses to mycobacteria via cathelicidin expression. J Immunol 2009, 182:3696-3705
-
(2009)
J Immunol
, vol.182
, pp. 3696-3705
-
-
Yang, C.1
Shin, D.2
Kim, K.3
Lee, Z.4
Lee, C.5
Park, S.G.6
Bae, Y.S.7
Jo, E.8
-
47
-
-
34848840994
-
Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis
-
Abdollahi-Roodsaz S, Joosten LA, Roelofs MF, Radstake TR, Matera G, Popa C, van der Meer JW, Netea MG, van den Berg WB: Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis. Arthritis Rheum 2007, 56:2957-2967
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2957-2967
-
-
Abdollahi-Roodsaz, S.1
Joosten, L.A.2
Roelofs, M.F.3
Radstake, T.R.4
Matera, G.5
Popa, C.6
Van Der Meer, J.W.7
Netea, M.G.8
Van Den Berg, W.B.9
-
48
-
-
73649088291
-
Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation
-
Abdollahi-Roodsaz S, Joosten LA, Koenders MI, van den Brand BT, van de Loo FA, van den Berg WB: Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation. Am J Pathol 2009, 175:2004-2013
-
(2009)
Am J Pathol
, vol.175
, pp. 2004-2013
-
-
Abdollahi-Roodsaz, S.1
Joosten, L.A.2
Koenders, M.I.3
Van Den Brand, B.T.4
Van De Loo, F.A.5
Van Den Berg, W.B.6
-
49
-
-
79960536837
-
Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis
-
Miranda-Hernandez S, Gerlach N, Fletcher JM, Biros E, Mack M, Korner H, Baxter AG: Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis. J Immunol 2011, 187:791-804
-
(2011)
J Immunol
, vol.187
, pp. 791-804
-
-
Miranda-Hernandez, S.1
Gerlach, N.2
Fletcher, J.M.3
Biros, E.4
Mack, M.5
Korner, H.6
Baxter, A.G.7
-
50
-
-
44849098196
-
Th17 development and autoimmune arthritis in the absence of reactive oxygen species
-
George-Chandy A, Nordstrom I, Nygren E, Jonsson IM, Postigo J, Collins LV, Eriksson K: Th17 development and autoimmune arthritis in the absence of reactive oxygen species. Eur J Immunol 2008, 38:1118-1126
-
(2008)
Eur J Immunol
, vol.38
, pp. 1118-1126
-
-
George-Chandy, A.1
Nordstrom, I.2
Nygren, E.3
Jonsson, I.M.4
Postigo, J.5
Collins, L.V.6
Eriksson, K.7
-
51
-
-
33748062329
-
T cell surface redox levels determine T cell reactivity and arthritis susceptibility
-
Gelderman KA, Hultqvist M, Holmberg J, Olofsson P, Holmdahl R: T cell surface redox levels determine T cell reactivity and arthritis susceptibility. Proc Natl Acad Sci U S A 2006, 103:12831-12836
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 12831-12836
-
-
Gelderman, K.A.1
Hultqvist, M.2
Holmberg, J.3
Olofsson, P.4
Holmdahl, R.5
-
52
-
-
32444448971
-
Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells
-
Wang J, Fathman JW, Lugo-Villarino G, Scimone L, von Andrian U, Dorfman DM, Glimcher LH: Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells. J Clin Invest 2006, 116:414-421
-
(2006)
J Clin Invest
, vol.116
, pp. 414-421
-
-
Wang, J.1
Fathman, J.W.2
Lugo-Villarino, G.3
Scimone, L.4
Von Andrian, U.5
Dorfman, D.M.6
Glimcher, L.H.7
-
53
-
-
34547199003
-
T cells are involved in the development of arthritis induced by anti-type II collagen antibody
-
Mitamura M, Nakano N, Yonekawa T, Shan L, Kaise T, Kobayashi T, Yamashita K, Kikkawa H, Kinoshita M: T cells are involved in the development of arthritis induced by anti-type II collagen antibody. Int Immunopharmacol 2007, 7:1360-1368
-
(2007)
Int Immunopharmacol
, vol.7
, pp. 1360-1368
-
-
Mitamura, M.1
Nakano, N.2
Yonekawa, T.3
Shan, L.4
Kaise, T.5
Kobayashi, T.6
Yamashita, K.7
Kikkawa, H.8
Kinoshita, M.9
-
54
-
-
0142213223
-
Collagen type II-specific monoclonal antibody-induced arthritis in mice: Description of the disease and the influence of age, sex, and genes
-
Nandakumar KS, Svensson L, Holmdahl R: Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes. Am J Pathol 2003, 163:1827-1837
-
(2003)
Am J Pathol
, vol.163
, pp. 1827-1837
-
-
Nandakumar, K.S.1
Svensson, L.2
Holmdahl, R.3
-
55
-
-
33748751857
-
Essential role of neutrophils in anti-type II collagen antibody and lipopolysaccharide-induced arthritis
-
Tanaka D, Kagari T, Doi H, Shimozato T: Essential role of neutrophils in anti-type II collagen antibody and lipopolysaccharide-induced arthritis. Immunology 2006, 119:195-202
-
(2006)
Immunology
, vol.119
, pp. 195-202
-
-
Tanaka, D.1
Kagari, T.2
Doi, H.3
Shimozato, T.4
-
56
-
-
77950364465
-
Neutrophils in a mouse model of autoantibody-mediated arthritis: Critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1
-
Monach PA, Nigrovic PA, Chen M, Hock H, Lee DM, Benoist C, Mathis D: Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1. Arthritis Rheum 2010, 62:753-764
-
(2010)
Arthritis Rheum
, vol.62
, pp. 753-764
-
-
Monach, P.A.1
Nigrovic, P.A.2
Chen, M.3
Hock, H.4
Lee, D.M.5
Benoist, C.6
Mathis, D.7
-
57
-
-
34548657163
-
Lack of reactive oxygen species breaks T cell tolerance to collagen type II and allows development of arthritis in mice
-
Hultqvist M, Bäcklund J, Bauer K, Gelderman KA, Holmdahl R: Lack of reactive oxygen species breaks T cell tolerance to collagen type II and allows development of arthritis in mice. J Immunol 2007, 179:1431-1437
-
(2007)
J Immunol
, vol.179
, pp. 1431-1437
-
-
Hultqvist, M.1
Bäcklund, J.2
Bauer, K.3
Gelderman, K.A.4
Holmdahl, R.5
-
58
-
-
0028984840
-
The P47phox mouse knock-out model of chronic granulomatous disease
-
Jackson SH, Gallin JI, Holland SM: The P47phox mouse knock-out model of chronic granulomatous disease. J Exp Med 1995, 182:751-758
-
(1995)
J Exp Med
, vol.182
, pp. 751-758
-
-
Jackson, S.H.1
Gallin, J.I.2
Holland, S.M.3
-
59
-
-
0141648399
-
Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models
-
van de Loo FA, Bennink MB, Arntz OJ, Smeets RL, Lubberts E, Joosten LA, van Lent PL, Coenen-de Roo CJ, Cuzzocrea S, Segal BH, Holland SM, van den Berg WB: Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models. Am J Pathol 2003, 163:1525-1537
-
(2003)
Am J Pathol
, vol.163
, pp. 1525-1537
-
-
Van De Loo, F.A.1
Bennink, M.B.2
Arntz, O.J.3
Smeets, R.L.4
Lubberts, E.5
Joosten, L.A.6
Van Lent, P.L.7
Coenen-de Roo, C.J.8
Cuzzocrea, S.9
Segal, B.H.10
Holland, S.M.11
Van Den Berg, W.B.12
|