메뉴 건너뛰기




Volumn 6, Issue 8, 2011, Pages

Toll-like receptor 2 induced angiogenesis and invasion is mediated through the tie2 signalling pathway in rheumatoid arthritis

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN; ANGIOPOIETIN RECEPTOR; GELATINASE A; GELATINASE B; INTERCELLULAR ADHESION MOLECULE 1; TOLL LIKE RECEPTOR 2; ANGIOPOIETIN 2; ANTIBODY; LIPOPEPTIDE; PAM(3)CSK(4) PEPTIDE;

EID: 80051728761     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023540     Document Type: Article
Times cited : (67)

References (53)
  • 1
    • 0142187335 scopus 로고    scopus 로고
    • Angiogenesis as a target in rheumatoid arthritis
    • Koch AE, (2003) Angiogenesis as a target in rheumatoid arthritis. Ann Rheum Dis 62: 60-67.
    • (2003) Ann Rheum Dis , vol.62 , pp. 60-67
    • Koch, A.E.1
  • 2
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N, Davis-Smyth T, (1997) The biology of vascular endothelial growth factor. Endocr Rev 18: 4-25.
    • (1997) Endocr Rev , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 3
    • 0026033431 scopus 로고
    • Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts
    • Bucala R, Ritchlin C, Winchester R, Cerami A, (1991) Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts. J Exp Med 173: 569-574.
    • (1991) J Exp Med , vol.173 , pp. 569-574
    • Bucala, R.1    Ritchlin, C.2    Winchester, R.3    Cerami, A.4
  • 4
    • 0026802287 scopus 로고
    • Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: implications for the role of cytokines in cartilage destruction and repair
    • Chu CQ, Field M, Allard S, Abney E, Feldmann M, et al. (1992) Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: implications for the role of cytokines in cartilage destruction and repair. Br J Rheumatol 10: 653-661.
    • (1992) Br J Rheumatol , vol.10 , pp. 653-661
    • Chu, C.Q.1    Field, M.2    Allard, S.3    Abney, E.4    Feldmann, M.5
  • 5
    • 0034545158 scopus 로고    scopus 로고
    • The pathogenesis and prevention of joint damage in rheumatoid arthritis: advances from synovial biopsy and tissue analysis
    • Tak PP, Bresnihan B, (2000) The pathogenesis and prevention of joint damage in rheumatoid arthritis: advances from synovial biopsy and tissue analysis. Arthritis Rheum 43: 2619-2633.
    • (2000) Arthritis Rheum , vol.43 , pp. 2619-2633
    • Tak, P.P.1    Bresnihan, B.2
  • 6
    • 0037378466 scopus 로고    scopus 로고
    • Expression and regulation of Toll-like receptor 2 in rheumatoid arthritis synovium
    • Seibl R, Birchler T, Loeliger S, Hossle JP, Gay RE, et al. (2003) Expression and regulation of Toll-like receptor 2 in rheumatoid arthritis synovium. Am J Pathol 162: 1221-1227.
    • (2003) Am J Pathol , vol.162 , pp. 1221-1227
    • Seibl, R.1    Birchler, T.2    Loeliger, S.3    Hossle, J.P.4    Gay, R.E.5
  • 7
    • 2342604896 scopus 로고    scopus 로고
    • Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis
    • Iwahashi M, Yamamura M, Aita T, Okamoto A, Ueno A, et al. (2004) Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis. Arthritis Rheum 2004 50: 1457-1467.
    • (2004) Arthritis Rheum 2004 , vol.50 , pp. 1457-1467
    • Iwahashi, M.1    Yamamura, M.2    Aita, T.3    Okamoto, A.4    Ueno, A.5
  • 8
    • 0033784930 scopus 로고    scopus 로고
    • Antigen-presenting cells containing bacterial peptidoglycan in synovial tissues of rheumatoid arthritis patients coexpress costimulatory molecules and cytokines
    • Schrijver IA, Melief MJ, Tak PP, Hazenberg MP, Laman JD, (2000) Antigen-presenting cells containing bacterial peptidoglycan in synovial tissues of rheumatoid arthritis patients coexpress costimulatory molecules and cytokines. Arthritis Rheum 43: 2160-2168.
    • (2000) Arthritis Rheum , vol.43 , pp. 2160-2168
    • Schrijver, I.A.1    Melief, M.J.2    Tak, P.P.3    Hazenberg, M.P.4    Laman, J.D.5
  • 9
    • 23044494509 scopus 로고    scopus 로고
    • The role of Toll-like receptor signalling in the pathogenesis of arthritis
    • Brentano F, Kyburz D, Schorr O, Gay R, Gay S, (2005) The role of Toll-like receptor signalling in the pathogenesis of arthritis. Cell Immunol 233: 90-96.
    • (2005) Cell Immunol , vol.233 , pp. 90-96
    • Brentano, F.1    Kyburz, D.2    Schorr, O.3    Gay, R.4    Gay, S.5
  • 10
    • 33947545388 scopus 로고    scopus 로고
    • The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis
    • Sacre SM, Andreakos E, Kiriakidis S, Amjadi P, Lundberg A, et al. (2007) The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis. Am J Pathol 2007 170: 518-525.
    • (2007) Am J Pathol 2007 , vol.170 , pp. 518-525
    • Sacre, S.M.1    Andreakos, E.2    Kiriakidis, S.3    Amjadi, P.4    Lundberg, A.5
  • 11
    • 0033510414 scopus 로고    scopus 로고
    • Distinct vascular patterns of early synovitis in psoriatic, reactive, and rheumatoid arthritis
    • Reece RJ, Canete JD, Parsons WJ, Emery P, Veale DJ, (1999) Distinct vascular patterns of early synovitis in psoriatic, reactive, and rheumatoid arthritis. Arthritis Rheum 42: 1481-1484.
    • (1999) Arthritis Rheum , vol.42 , pp. 1481-1484
    • Reece, R.J.1    Canete, J.D.2    Parsons, W.J.3    Emery, P.4    Veale, D.J.5
  • 12
    • 0037309635 scopus 로고    scopus 로고
    • Angiopoietins, growth factors, and vascular morphology in early arthritis
    • 200330
    • Fearon U, Griosios K, Fraser A, Reece R, Emery P, et al. (2003) Angiopoietins, growth factors, and vascular morphology in early arthritis. J Rheumatol 200330: 260-268.
    • (2003) J Rheumatol , pp. 260-268
    • Fearon, U.1    Griosios, K.2    Fraser, A.3    Reece, R.4    Emery, P.5
  • 13
    • 0028199835 scopus 로고
    • Vascular endothelial growth factor A cytokine modulating endothelial function in rheumatoid arthritis
    • Koch AE, Harlow LA, Haines GK, Amento EP, Unemori EN, et al. (1994) Vascular endothelial growth factor A cytokine modulating endothelial function in rheumatoid arthritis. J Immunol 1994 152: 4149-4156.
    • (1994) J Immunol 1994 , vol.152 , pp. 4149-4156
    • Koch, A.E.1    Harlow, L.A.2    Haines, G.K.3    Amento, E.P.4    Unemori, E.N.5
  • 14
    • 0035670380 scopus 로고    scopus 로고
    • TGF beta is required for the formation of capillary-like structures in three-dimensional cocultures of 10T1/2 and endothelial cells
    • Darland DC, D'Amore PA, (2001) TGF beta is required for the formation of capillary-like structures in three-dimensional cocultures of 10T1/2 and endothelial cells. Angiogenesis 4: 11-20.
    • (2001) Angiogenesis , vol.4 , pp. 11-20
    • Darland, D.C.1    D'Amore, P.A.2
  • 15
    • 0037143737 scopus 로고    scopus 로고
    • Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo
    • Lobov IB, Brooks PC, Lang RA, (2002) Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo. Proc Natl Acad Sci USA 99: 11205-11210.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 11205-11210
    • Lobov, I.B.1    Brooks, P.C.2    Lang, R.A.3
  • 16
    • 0032504752 scopus 로고    scopus 로고
    • Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization
    • Asahara T, Chen D, Takahashi T, Fujikawa K, Kearney M, et al. (1998) Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization. Circ Res 83: 233-240.
    • (1998) Circ Res , vol.83 , pp. 233-240
    • Asahara, T.1    Chen, D.2    Takahashi, T.3    Fujikawa, K.4    Kearney, M.5
  • 17
    • 58249114895 scopus 로고    scopus 로고
    • Differential roles of PDGFR-alpha and PDGFR-beta in angiogenesis and vessel stability
    • Zhang J, Cao R, Zhang Y, Jia T, Cao Y, et al. (2009) Differential roles of PDGFR-alpha and PDGFR-beta in angiogenesis and vessel stability. FASEB J pp. 23153-163.
    • (2009) FASEB J , pp. 23153-23163
    • Zhang, J.1    Cao, R.2    Zhang, Y.3    Jia, T.4    Cao, Y.5
  • 18
    • 36349030423 scopus 로고    scopus 로고
    • Placental growth factor-1 attenuates vascular endothelial growth factor-A-dependent tumor angiogenesis during beta cell carcinogenesis
    • Schomber T, Kopfstein L, Djonov V, Albrecht I, Baeriswyl V, et al. (2007) Placental growth factor-1 attenuates vascular endothelial growth factor-A-dependent tumor angiogenesis during beta cell carcinogenesis. Cancer Res 67: 10840-10848.
    • (2007) Cancer Res , vol.67 , pp. 10840-10848
    • Schomber, T.1    Kopfstein, L.2    Djonov, V.3    Albrecht, I.4    Baeriswyl, V.5
  • 19
    • 10444278132 scopus 로고    scopus 로고
    • Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma
    • Radstake TR, Roelofs MF, Jenniskens YM, Oppers-Walgreen B, van Riel PL, et al. (2004) Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma. Arthritis Rheum 50: 3856-3865.
    • (2004) Arthritis Rheum , vol.50 , pp. 3856-3865
    • Radstake, T.R.1    Roelofs, M.F.2    Jenniskens, Y.M.3    Oppers-Walgreen, B.4    van Riel, P.L.5
  • 20
    • 33846681858 scopus 로고    scopus 로고
    • Toll-like receptor 2 ligand mediates the upregulation of angiogenic factor, vascular endothelial growth factor and interleukin-8/CXCL8 in human rheumatoid synovial fibroblasts
    • Cho ML, Ju JH, Kim HR, Oh HJ, Kang CM, et al. (2007) Toll-like receptor 2 ligand mediates the upregulation of angiogenic factor, vascular endothelial growth factor and interleukin-8/CXCL8 in human rheumatoid synovial fibroblasts. Immunol Lett 108: 121-128.
    • (2007) Immunol Lett , vol.108 , pp. 121-128
    • Cho, M.L.1    Ju, J.H.2    Kim, H.R.3    Oh, H.J.4    Kang, C.M.5
  • 21
    • 33750524249 scopus 로고    scopus 로고
    • TLR-2-mediated induction of vascular endothelial growth factor (VEGF) in cartilage in septic joint disease
    • Varoga D, Paulsen F, Mentlein R, Fay J, Kurz B, et al. (2006) TLR-2-mediated induction of vascular endothelial growth factor (VEGF) in cartilage in septic joint disease. J Pathol 210: 315-324.
    • (2006) J Pathol , vol.210 , pp. 315-324
    • Varoga, D.1    Paulsen, F.2    Mentlein, R.3    Fay, J.4    Kurz, B.5
  • 22
    • 60449100137 scopus 로고    scopus 로고
    • HSV immune complex (HSV-IgG: IC) and HSV-DNA elicit the production of angiogenic factor VEGF and MMP-9
    • Hayashi K, Hooper LC, Detrick B, Hooks JJ, (2009) HSV immune complex (HSV-IgG: IC) and HSV-DNA elicit the production of angiogenic factor VEGF and MMP-9. Arch Virol 154: 219-226.
    • (2009) Arch Virol , vol.154 , pp. 219-226
    • Hayashi, K.1    Hooper, L.C.2    Detrick, B.3    Hooks, J.J.4
  • 23
    • 33750289939 scopus 로고    scopus 로고
    • Oncostatin M induces angiogenesis and cartilage degradation in rheumatoid arthritis synovial tissue and human cartilage cocultures
    • Fearon U, Mullan R, Markham T, Connolly M, Sullivan S, et al. (2006) Oncostatin M induces angiogenesis and cartilage degradation in rheumatoid arthritis synovial tissue and human cartilage cocultures. Arthritis Rheum 54: 3152-3162.
    • (2006) Arthritis Rheum , vol.54 , pp. 3152-3162
    • Fearon, U.1    Mullan, R.2    Markham, T.3    Connolly, M.4    Sullivan, S.5
  • 24
    • 79951854918 scopus 로고    scopus 로고
    • Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures
    • Feb 23;13, [Epub ahead of Print]
    • Nic An Ultaigh S, Saber TP, McCormick J, Connolly M, Dellacasagrande J, et al. (2011) Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures. Arthritis Res Ther Feb 23;13 (1): R33 [Epub ahead of Print].
    • (2011) Arthritis Res Ther , Issue.1
    • Nic An Ultaigh, S.1    Saber, T.P.2    McCormick, J.3    Connolly, M.4    Dellacasagrande, J.5
  • 25
    • 77953431572 scopus 로고    scopus 로고
    • Acute serum amyloid A induces migration, angiogenesis, and inflammation in synovial cells in vitro and in a human rheumatoid arthritis/SCID mouse chimera model
    • Connolly M, Marrelli A, Blades M, McCormick J, Maderna P, et al. (2010) Acute serum amyloid A induces migration, angiogenesis, and inflammation in synovial cells in vitro and in a human rheumatoid arthritis/SCID mouse chimera model. J Immunol 184: 6427-37.
    • (2010) J Immunol , vol.184 , pp. 6427-6437
    • Connolly, M.1    Marrelli, A.2    Blades, M.3    McCormick, J.4    Maderna, P.5
  • 26
    • 65249190995 scopus 로고    scopus 로고
    • Heat Shockprotein 96 is elevated in rheumatoid arthritis and activates macrophages primarilty via TLR2 signalling
    • Huang Q, Sobkoviak R, Jockheck-Clark AR, Shi B, Mandelin AR, et al. (2009) Heat Shockprotein 96 is elevated in rheumatoid arthritis and activates macrophages primarilty via TLR2 signalling. J Immunol 182: 4965-73.
    • (2009) J Immunol , vol.182 , pp. 4965-4973
    • Huang, Q.1    Sobkoviak, R.2    Jockheck-Clark, A.R.3    Shi, B.4    Mandelin, A.R.5
  • 27
    • 34447332240 scopus 로고    scopus 로고
    • Synovial fibronection fragmentation and domain expressions in relation to rheumatoid arthritis progression
    • Przybysz, Borysewicz K, Szechinski J, Katnik-Prastowska I, (2007) Synovial fibronection fragmentation and domain expressions in relation to rheumatoid arthritis progression. Rheumatology 46: 1071-1075.
    • (2007) Rheumatology , vol.46 , pp. 1071-1075
    • Przybysz1    Borysewicz, K.2    Szechinski, J.3    Katnik-Prastowska, I.4
  • 28
    • 0030987868 scopus 로고    scopus 로고
    • Soluble oligonucleaosomal complexes in synovial fluid from inflamed joints
    • Yu D, Rumore PM, Liu Q, Steinman CR, (1997) Soluble oligonucleaosomal complexes in synovial fluid from inflamed joints. Arthritis Rheum 40: 648-654.
    • (1997) Arthritis Rheum , vol.40 , pp. 648-654
    • Yu, D.1    Rumore, P.M.2    Liu, Q.3    Steinman, C.R.4
  • 29
    • 0037386810 scopus 로고    scopus 로고
    • High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine
    • Taniguchi N, Kawahara K, Yone K, Hashiguchi T, Yamakuchi M, et al. (2003) High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine. Arthritis Rheum 48: 971-81.
    • (2003) Arthritis Rheum , vol.48 , pp. 971-981
    • Taniguchi, N.1    Kawahara, K.2    Yone, K.3    Hashiguchi, T.4    Yamakuchi, M.5
  • 30
    • 3342894125 scopus 로고    scopus 로고
    • Therapeutic inhibition of leukocyte recruitment in inflammatory diseases
    • Szekanecz Z, Koch AE, (2004) Therapeutic inhibition of leukocyte recruitment in inflammatory diseases. Curr Opin Pharmacol 4: 423-428.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 423-428
    • Szekanecz, Z.1    Koch, A.E.2
  • 31
    • 73349128100 scopus 로고    scopus 로고
    • Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis
    • Monaco C, Gregan SM, Navin TJ, Foxwell BM, Davies AH, et al. (2009) Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis. Circulation 120: 2462-2469.
    • (2009) Circulation , vol.120 , pp. 2462-2469
    • Monaco, C.1    Gregan, S.M.2    Navin, T.J.3    Foxwell, B.M.4    Davies, A.H.5
  • 32
    • 77950554962 scopus 로고    scopus 로고
    • Toll-like receptor 2/6 stimulation promotes angiogenesis via GM-CSF as a potential strategy for immune defense and tissue regeneration
    • Grote K, Schuett H, Salguero G, Grothusen C, Jagielska J, et al. (2010) Toll-like receptor 2/6 stimulation promotes angiogenesis via GM-CSF as a potential strategy for immune defense and tissue regeneration. Blood 115: 2543-52.
    • (2010) Blood , vol.115 , pp. 2543-2552
    • Grote, K.1    Schuett, H.2    Salguero, G.3    Grothusen, C.4    Jagielska, J.5
  • 33
    • 0036237242 scopus 로고    scopus 로고
    • Differential expression of the angiogenic Tie receptor family in arthritic and normal synovial tissue
    • Shahrara S, Volin MV, Connors MA, Haines GK, Koch AE, (2002) Differential expression of the angiogenic Tie receptor family in arthritic and normal synovial tissue. Arthritis Res 4: 201-208.
    • (2002) Arthritis Res , vol.4 , pp. 201-208
    • Shahrara, S.1    Volin, M.V.2    Connors, M.A.3    Haines, G.K.4    Koch, A.E.5
  • 34
    • 32244436305 scopus 로고    scopus 로고
    • Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation
    • Fiedler U, Reiss Y, Scharpfenecker M, Grunow V, Koidl S, et al. (2006) Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation. Nat Med 12: 235-239.
    • (2006) Nat Med , vol.12 , pp. 235-239
    • Fiedler, U.1    Reiss, Y.2    Scharpfenecker, M.3    Grunow, V.4    Koidl, S.5
  • 35
    • 72449200580 scopus 로고    scopus 로고
    • Hemorrhagic shock augments lung endothelial cell activation: role of temporal alterations of TLR4 and TLR2
    • Li Y, Xiang M, Yuan Y, Xiao G, Zhang J, et al. (2009) Hemorrhagic shock augments lung endothelial cell activation: role of temporal alterations of TLR4 and TLR2. Am J Physiol Regul Integr Comp Physiol 2009 pp. 2971670-1680.
    • (2009) Am J Physiol Regul Integr Comp Physiol 2009 , pp. 2971670-2971680
    • Li, Y.1    Xiang, M.2    Yuan, Y.3    Xiao, G.4    Zhang, J.5
  • 36
    • 48149109440 scopus 로고    scopus 로고
    • Leukocyte adhesion molecule and chemokine production through lipoteichoic acid recognition by toll-like receptor 2 in cultured human lymphatic endothelium
    • Sawa Y, Tsuruga E, Iwasawa K, Ishikawa H, Yoshida S, (2008) Leukocyte adhesion molecule and chemokine production through lipoteichoic acid recognition by toll-like receptor 2 in cultured human lymphatic endothelium. Cell Tissue Res 333: 237-252.
    • (2008) Cell Tissue Res , vol.333 , pp. 237-252
    • Sawa, Y.1    Tsuruga, E.2    Iwasawa, K.3    Ishikawa, H.4    Yoshida, S.5
  • 37
    • 34247154495 scopus 로고    scopus 로고
    • Peptidoglycan increases firm adhesion of monocytes under flow conditions and primes monocyte chemotaxis
    • Nijhuis MM, Pasterkamp G, Sluis NI, de Kleijn DP, Laman JD, et al. (2007) Peptidoglycan increases firm adhesion of monocytes under flow conditions and primes monocyte chemotaxis. J Vasc Res 44: 214-222.
    • (2007) J Vasc Res , vol.44 , pp. 214-222
    • Nijhuis, M.M.1    Pasterkamp, G.2    Sluis, N.I.3    de Kleijn, D.P.4    Laman, J.D.5
  • 38
    • 0037333990 scopus 로고    scopus 로고
    • Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll-like receptor signaling
    • Kyburz D, Rethage J, Seibl R, Lauener R, Gay RE, et al. (2003) Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll-like receptor signaling. Arthritis Rheum 48: 642-650.
    • (2003) Arthritis Rheum , vol.48 , pp. 642-650
    • Kyburz, D.1    Rethage, J.2    Seibl, R.3    Lauener, R.4    Gay, R.E.5
  • 40
    • 0035437168 scopus 로고    scopus 로고
    • Transendothelial migration of lymphocytes across high endothelial venules into lymph nodes is affected by metalloproteinases
    • Faveeuw C, Preece G, Ager A, (2001) Transendothelial migration of lymphocytes across high endothelial venules into lymph nodes is affected by metalloproteinases. Blood 98: 688-695.
    • (2001) Blood , vol.98 , pp. 688-695
    • Faveeuw, C.1    Preece, G.2    Ager, A.3
  • 41
    • 0036138771 scopus 로고    scopus 로고
    • Gelatinase expression and activity in the synovium and skin of patients with erosive psoriatic arthritis
    • Hitchon CA, Danning CL, Illei GG, El-Gabalawy HS, Boumpas DT, (2002) Gelatinase expression and activity in the synovium and skin of patients with erosive psoriatic arthritis. J Rheumatol 29: 107-117.
    • (2002) J Rheumatol , vol.29 , pp. 107-117
    • Hitchon, C.A.1    Danning, C.L.2    Illei, G.G.3    El-Gabalawy, H.S.4    Boumpas, D.T.5
  • 42
    • 47049095760 scopus 로고    scopus 로고
    • Elevated circulatory MMP-2 and MMP-9 levels and activities in patients with rheumatoid arthritis and systemic lupus erythematosus
    • Chang YH, Lin IL, Tsay GJ, Yang SC, Yang TP, et al. (2008) Elevated circulatory MMP-2 and MMP-9 levels and activities in patients with rheumatoid arthritis and systemic lupus erythematosus. Clin Biochem 41: 955-959.
    • (2008) Clin Biochem , vol.41 , pp. 955-959
    • Chang, Y.H.1    Lin, I.L.2    Tsay, G.J.3    Yang, S.C.4    Yang, T.P.5
  • 43
    • 34547770721 scopus 로고    scopus 로고
    • In vivo inhibition of angiogenesis by interleukin-13 gene therapy in a rat model of rheumatoid arthritis
    • Haas CS, Amin MA, Ruth JH, Allen BL, Ahmed S, et al. (2007) In vivo inhibition of angiogenesis by interleukin-13 gene therapy in a rat model of rheumatoid arthritis. Arthritis Rheum 56: 2535-2548.
    • (2007) Arthritis Rheum , vol.56 , pp. 2535-2548
    • Haas, C.S.1    Amin, M.A.2    Ruth, J.H.3    Allen, B.L.4    Ahmed, S.5
  • 44
    • 1642506185 scopus 로고    scopus 로고
    • ERK1-2 and p38 MAPK regulate MMP/TIMP balance and function in response to thrombospondin-1 fragments in the microvascular endothelium
    • Donnini S, Morbidelli L, Taraboletti G, Ziche M, (2004) ERK1-2 and p38 MAPK regulate MMP/TIMP balance and function in response to thrombospondin-1 fragments in the microvascular endothelium. Life Sci 74: 2975-2985.
    • (2004) Life Sci , vol.74 , pp. 2975-2985
    • Donnini, S.1    Morbidelli, L.2    Taraboletti, G.3    Ziche, M.4
  • 45
    • 0033580889 scopus 로고    scopus 로고
    • Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF
    • Holash J, Maisonpierre PC, Compton D, Boland P, Alexander CR, et al. (1999) Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF. Science 284: 1994-1998.
    • (1999) Science , vol.284 , pp. 1994-1998
    • Holash, J.1    Maisonpierre, P.C.2    Compton, D.3    Boland, P.4    Alexander, C.R.5
  • 46
    • 15144358851 scopus 로고    scopus 로고
    • Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis
    • Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, et al. (1997) Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis. Science 277: 55-60.
    • (1997) Science , vol.277 , pp. 55-60
    • Maisonpierre, P.C.1    Suri, C.2    Jones, P.F.3    Bartunkova, S.4    Wiegand, S.J.5
  • 47
    • 0030480322 scopus 로고    scopus 로고
    • Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis
    • Suri C, Jones PF, Patan S, Bartunkova S, Maisonpierre PC, et al. (1996) Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis. Cell 87: 1171-1180.
    • (1996) Cell , vol.87 , pp. 1171-1180
    • Suri, C.1    Jones, P.F.2    Patan, S.3    Bartunkova, S.4    Maisonpierre, P.C.5
  • 48
    • 34247363201 scopus 로고    scopus 로고
    • Expression of angiopoietin-1 in osteoblasts and its inhibition by tumor necrosis factor-alpha and interferon-gamma
    • Kasama T, Isozaki T, Odai T, Matsunawa M, Wakabayashi K, et al. (2007) Expression of angiopoietin-1 in osteoblasts and its inhibition by tumor necrosis factor-alpha and interferon-gamma. Translational Research 149: 265-273.
    • (2007) Translational Research , vol.149 , pp. 265-273
    • Kasama, T.1    Isozaki, T.2    Odai, T.3    Matsunawa, M.4    Wakabayashi, K.5
  • 49
    • 1242274550 scopus 로고    scopus 로고
    • Autocrine/paracrine role of the angiopoietin-1 and -2/Tie2 system in cell proliferation and chemotaxis of cultured fibroblastic synoviocytes in rheumatoid arthritis
    • Takahara K, Iioka T, Furukawa K, Uchida T, Nakashima M, et al. (2004) Autocrine/paracrine role of the angiopoietin-1 and-2/Tie2 system in cell proliferation and chemotaxis of cultured fibroblastic synoviocytes in rheumatoid arthritis. Human Pathology 35: 150-158.
    • (2004) Human Pathology , vol.35 , pp. 150-158
    • Takahara, K.1    Iioka, T.2    Furukawa, K.3    Uchida, T.4    Nakashima, M.5
  • 50
    • 0037310605 scopus 로고    scopus 로고
    • Angiopoietin-1 is expressed in the synovium of patients with rheumatoid arthritis and is induced by tumour necrosis factor-alpha
    • Gravallese EM, Pettit AR, Lee R, Madore R, Manning C, et al. (2003) Angiopoietin-1 is expressed in the synovium of patients with rheumatoid arthritis and is induced by tumour necrosis factor-alpha. Ann Rheum Dis 62: 100-107.
    • (2003) Ann Rheum Dis , vol.62 , pp. 100-107
    • Gravallese, E.M.1    Pettit, A.R.2    Lee, R.3    Madore, R.4    Manning, C.5
  • 51
    • 0036160784 scopus 로고    scopus 로고
    • Constitutive Expression of Angiopoietin-1 and -2 and Modulation of Their Expression by Inflammatory Cytokines in Rheumatoid Arthritis Synovial Fibroblasts
    • Scott B, Zaratin P, Colombo A, Hansbury M, Winkler J, et al. (2002) Constitutive Expression of Angiopoietin-1 and-2 and Modulation of Their Expression by Inflammatory Cytokines in Rheumatoid Arthritis Synovial Fibroblasts. Journal of Rheumatology 29: 230-239.
    • (2002) Journal of Rheumatology , vol.29 , pp. 230-239
    • Scott, B.1    Zaratin, P.2    Colombo, A.3    Hansbury, M.4    Winkler, J.5
  • 52
    • 18644372654 scopus 로고    scopus 로고
    • Gene therapy targeting the Tie2 function ameliorates collagen-induced arthritis and protects against bone destruction
    • Chen Y, Donnelly E, Kobayashi H, DeBusk LM, Lin PC, (2005) Gene therapy targeting the Tie2 function ameliorates collagen-induced arthritis and protects against bone destruction. ArthritisRheum 52: 1585-1594.53.
    • (2005) ArthritisRheum , vol.52 , pp. 1585-1594
    • Chen, Y.1    Donnelly, E.2    Kobayashi, H.3    DeBusk, L.M.4    Lin, P.C.5
  • 53
    • 0141453482 scopus 로고    scopus 로고
    • Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor alpha-induced angiogenesis in rheumatoid arthritis
    • DeBusk LM, Chen Y, Nishishita T, Chen J, Thomas JW, et al. (2003) Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor alpha-induced angiogenesis in rheumatoid arthritis. Arthritis Rheum 48: 2461-2471.
    • (2003) Arthritis Rheum , vol.48 , pp. 2461-2471
    • DeBusk, L.M.1    Chen, Y.2    Nishishita, T.3    Chen, J.4    Thomas, J.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.