Investigation into the influence of primary crystallization conditions on the mechanical properties and secondary processing behaviour of fluticasone propionate for carrier based dry powder inhaler formulations

Pharmaceutical Research

Volumn 29, Issue 4, 2012, Pages 994-1006

  Kubavat, Harshal A ^a   Shur, Jagdeep ^a   Ruecroft, Graham ^b   Hipkiss, David ^b   Price, Robert ^a  

^a University of Bath   (United Kingdom)

^b Prosonix Ltd   (United Kingdom)

Author keywords

Cohesive adhesive balance; Dry powder inhaler; Mechanical; Micronization; Nanoindentation

Indexed keywords

FLUTICASONE PROPIONATE; LACTOSE; SALMETEROL XINAFOATE;

AEROSOL; ARTICLE; ATOMIC FORCE MICROSCOPY; BINDING AFFINITY; CONTROLLED STUDY; CRYSTALLIZATION; DRUG DETERMINATION; DRUG FORMULATION; DRUG STRUCTURE; IN VITRO STUDY; NANOANALYSIS; PARTICLE SIZE; PHYSICAL CHEMISTRY; POWDER INHALER; PRIORITY JOURNAL; SURFACE PROPERTY; YOUNG MODULUS;

ADHESIVENESS; ANDROSTADIENES; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DRY POWDER INHALERS; ELASTIC MODULUS; EXCIPIENTS; MECHANICAL PHENOMENA; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, SCANNING; NANOTECHNOLOGY; PARTICLE SIZE; SURFACE PROPERTIES;

EID: 84862666824     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0640-1     Document Type: Article

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