Chrysotoxine, a novel bibenzyl compound selectively antagonizes MPP+, but not rotenone, neurotoxicity in dopaminergic SH-SY5Y cells

Neuroscience Letters

Volumn 521, Issue 1, 2012, Pages 76-81

  Song, Ju Xian ^a   Shaw, Pang Chui ^b   Wong, Ngok Shun ^c   Sze, Cho Wing ^a   Yao, Xin Sheng ^d   Tang, Chi Wai ^e   Tong, Yao ^a   Zhang, Yan Bo ^a  

^a THE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^d JINAN UNIVERSITY   (China)

^e UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Akt; Chrysotoxine; Mitochondrial dysfunctions; NF B; Rotenone

Indexed keywords

1 METHYL 4 PHENYL PYRIDINIUM; BIBENZYL DERIVATIVE; CALCIUM; CASPASE 3; CHRYSOTOBIBENZYL; CHRYSOTOXINE; CREPIDATIN; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MOSCATILIN; NEUROPROTECTIVE AGENT; NOBILIN B; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN KINASE B; PYRIDINIUM DERIVATIVE; REACTIVE OXYGEN METABOLITE; ROTENONE; UNCLASSIFIED DRUG;

ARTICLE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOPAMINERGIC NERVE CELL; HUMAN; HUMAN CELL; NEUROTOXICITY; PRIORITY JOURNAL;

EID: 84862607463     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.05.063     Document Type: Article

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