Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen

Blood

Volumn 119, Issue 23, 2012, Pages 5492-5501

  Ochsenreither, Sebastian ^a,b   Majeti, Ravindra ^c   Schmitt, Thomas ^a   Stirewalt, Derek ^a   Keilholz, Ulrich ^b   Loeb, Keith R ^a,d   Wood, Brent ^d   Choi, Yongiae E ^a   Bleakley, Marie ^a   Warren, Edus H ^a,e   Hudecek, Michael ^a   Akatsuka, Yoshiki ^f,g   Weissman, Irving L ^c   Greenberg, Philip D ^a,e  

^a Fred Hutchinson Cancer Research Center   (United States)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^f AICHI CANCER CENTER HOSPITAL   (Japan)

^g FUJITA HEALTH UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CANCER TESTIS ANTIGEN; CYCLIN A1; HLA A ANTIGEN; HLA A0201 ANTIGEN; OKT 3; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ALLOGENEIC STEM CELL TRANSPLANTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; CANCER STEM CELL; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CELL SUBPOPULATION; CELL SURVIVAL; CONTROLLED STUDY; DENDRITIC CELL; GENE EXPRESSION; GENE TARGETING; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGENICITY; LEUKEMIA CELL; LEUKEMIA STEM CELL; LEUKEMOGENESIS; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE LIBRARY; PRIORITY JOURNAL; PROTEIN FUNCTION; T LYMPHOCYTE; TARGET CELL; TESTIS; TISSUES; TUMOR XENOGRAFT;

EID: 84862578742     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-07-365890     Document Type: Article

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