Quantitative Detection of Circulating Tumor Cells in Cutaneous and Ocular Melanoma and Quality Assessment by Real-Time Reverse Transcriptase-Polymerase Chain Reaction

Clinical Cancer Research

Volumn 10, Issue 5, 2004, Pages 1605-1612

  Keilholz, Ulrich ^a   Goldin Lang, Petra ^a   Bechrakis, Nikolaos E ^a   Max, Nicole ^a   Letsch, Anne ^a   Schmittel, Alexander ^a   Scheibenbogen, Carmen ^a   Heufelder, Karin ^a   Eggermont, Alexander ^b   Thiel, Eckhard ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 100; LACTATE DEHYDROGENASE; MELAN A; MONOPHENOL MONOOXYGENASE; PORPHOBILINOGEN DEAMINASE;

ARTICLE; CANCER STAGING; CONTROLLED STUDY; HOUSEKEEPING GENE; HUMAN; HUMAN TISSUE; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER METASTASIS; MELANOMA CELL; METASTASIS; PRIORITY JOURNAL; PROGNOSIS; QUALITY CONTROL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; TUMOR VOLUME; UVEA MELANOMA;

ANTIGENS, NEOPLASM; BASE SEQUENCE; DNA PRIMERS; EYE NEOPLASMS; HUMANS; HYDROXYMETHYLBILANE SYNTHASE; MELANOMA; MEMBRANE GLYCOPROTEINS; MONOPHENOL MONOOXYGENASE; NEOPLASM PROTEINS; PLASMIDS; REFERENCE VALUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC;

EID: 12144288875     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-0610-3     Document Type: Article

References (48)

1. Roberts, W. M., Estrov, Z., Ouspenskaia, M. V., Johnston, D. A., McClain, K. L., and Zipf, T. F. Measurement of residual leukemia during remission in childhood acute lymphoblastic leukemia. N. Engl. J. Med., 336: 317-323, 1997.
2. Olavarria, E., Kanfer, E., Szydlo, R., Kaeda, J., Rezvani, K., Cwynarski, K., Pocock, C., Dazzi, F., Craddock, C., Apperley, J. F., Cross, N. C., and Goldman, J. M. Early detection of BCR-ABL transcripts by quantitative reverse transcriptase-polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for chronic myeloid leukemia. Blood, 97: 1560-1565, 2001.
3. Andersen, N. S., Donovan, J. W., Borus, J. S., Poor, C. M., Neuberg, D., Aster, J. C., Nadler, L. M., Freedman, A. S., and Gribben, J. G. Failure of immunologic purging in mantle cell lymphoma assessed reaction detection of minimal residual disease. Blood, 15: 4212-4221, 1997.
4. Davies, F. E., Forsyth, P. D., Rawstron, A. C., Owen, R. G., Pratt, G., Evans, P. A., Richards, S. J., Drayson, M., Smith, G. M., Selby, P. J., Child, J. A., and Morgan, G. J. The impact of attaining a minimal disease state after high-dose autologous transplantation for multiple myeloma. Br. J. Haematol., 112: 814-819, 2001.
5. Smith, B., Selby, P., Southgate, J., Pittman, K., Bradley, C., and Blair, G. E. Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polymerase chain reaction. Lancet, 338: 1227-1229, 1991.
6. Brossart, P., Schmier, J-W., Krüger, S., Willhauck, M., Scheibenbogen, C., Möhler, T., and Keilholz, U. A polymerase chain reaction-based semi-quantitative assessment of malignant melanoma cells in peripheral blood. Cancer Res., 55: 4056-4068, 1995.
7. Battayani, Z., Grob, J. J., Xerri, L., Noe, C., Zarour, H., Houvaenrghel, G., Delpero, J. R., Birmbaum, D., Hassoun, J., and Bonerandi, J. J. Polymerase chain reaction detection of circulating melanocytes as a prognostic marker in patients with melanoma. Arch. Dermatol., 131: 443-447, 1995.
8. Mellado, B., Gutierrez, L., Castel, T., Colomer, D., Fontanillas, M., Castro, J., and Estape, J. Prognostic siginificance of the detection of circulating malignant cells by reverse transcriptase-PCR in long-term clinically disease-free melanoma patients. Clin. Cancer Res., 5: 1843-1848, 1999.
9. Hoon, D. S. B., Bostick, P., Kuo, C., Okamoto, T., Wang, H-J., Elashoff, R., and Morton, D. L. Molecular markers in blood as surrogate prognostic indicators of melanoma recurrence. Cancer Res., 60: 2253-2257, 2000.
10. Curry, B. J., Myers, K., and Hersey, P. Utility of tests for circulating melanoma cells in identifying patients who develop recurrent melanoma. Recent Results Cancer Res., 158: 211-230, 2001.
11. Brossart, P., Keilholz, U., Willhauck, M., Scheibenbogen, C., Möhler, T., and Hunstein, W. Hematogenous spread of malignant melanoma cells in different stages of disease. J. Investig. Dermatol., 101: 887-889, 1993.
12. Tobal, K., Sherman, L. S., Foss, A. J., and Lightman, S. L. Detection of melanocytes from uveal melanoma in peripheral blood using the polymerase chain reaction. Investig. Ophthalmol. Vis. Sci., 34: 2622-2625, 1993.
13. Foss, A. J., Guille, M. J., Occleston, N. L., Hykin, P. G., Hungerford, J. L., and Lightman, S. The detection of melanoma cells in peripheral blood by reverse transcription polymerase chain reaction. Br. J. Cancer, 72: 155-159, 1995.
14. Ghossein, R. A., Coit, D., Brennan, M., Zhang, Z. F., Wang, Y., Bhattacharya, S., Houghton, A., and Rosai, J. Prognostic significance of peripheral blood and bone marrow tyrosinase messenger RNA in malignant melanoma. Clin. Cancer Res., 4: 419-428, 1998.
15. Palmieri, G., Strazzullo, M., Ascierto, P. A., Satriano, S. M. R., Daponte, A., and Castello, G. for the Melanoma Cooperative Group. Polymerase chain reaction-based detection of circulating melanoma cells as an effective marker of tumor progression. Melanoma Cooperative Group. J. Clin. Oncol., 17: 304-311, 1999.
16. Schittek, B., Bodingbauer, Y., Ellwanger, U., Blaheta, H. J., and Garbe, C. Amplification of MelanA messenger RNA in addition to tyrosinase increases sensitivity of melanoma cell detection in peripheral blood and is associated with the clinical stage and prognosis of malignant melanoma. Br. J. Dermatol., 141: 30-36, 1999.
17. Schittek, B., Blaheta, H-J., Flörchinger, G., Sauer, B., and Garbe, C. Increased sensitivity for the detection of malignant melanoma cells in peripheral blood using an improved protocol for reverse transcription-polymerase chain reaction. Br. J. Dermatol., 141: 37-43, 1999.
18. de Vries, T. J., Fourkour, A., Punt, C. J., van de Locht, L. T., Wobbes, T., van den Bosch, S., de Rooij, M. J., Mensink, E. J., Ruiter, D. J., and van Muijen, G. N. Reproducibility of detection of tyrosinase and MART-1 transcripts in the peripheral blood of melanoma patients: a quality control study using real-time quantitative RT-PCR. Br. J. Cancer, 80: 883-891, 1999.
19. Berking, C., Schlüpen, E-M., Schrader, A., Atzpodien, J., and Volkenandt, M. Tumor markers in peripheral blood of patients with malignant melanoma: Multimarker RT-PCR versus a luminoimmunometric assay for S-100. Arch. Dermatol. Res. 291: 479-484, 1999.
20. Voit, C., Schoengen, A., Schwurzer, M., Weber, L., Mayer, T., and Proebstle, T. M. detection of regional melanoma metastases by ultrasound B-scan, cytology or tyrosinase RT-PCR of fine-needle aspirates. Br. J. Cancer, 80: 1672-1677, 1999.
21. Le Bricon, T., Stoitchkov, K., Letellier, S., Guibal, F., Spy, J., Garnier, J. P., and Bousquet, B. Simultaneous analysis of tyrosinase mRNA and markers of tyrosinase activity in the blood of patients with metastatic melanoma. Clin. Chim. Acta, 282: 101-113, 1999.
22. Curry, B. J., Myers, K., and Hersey, P. MART-1 is expressed less frequently on circulating melanoma cells in patients who develop distant compared with locoregional metastases. J. Clin. Oncol., 17: 2562-2571, 1999.
23. Hanekom, G. S., Stubbings, H. M., Johnson, C. A., and Kidson, S. H. The detection of circulating melanoma cells correlates with tumour thickness and ulceration but is not predictive of metastasis for patients with primary melanoma. Melanoma Res., 9: 465-473, 1999.
24. Alao, J. P., Mohammed, M. Q., Slade, M. J., and Retsas, S. Detection of tyrosinase mRNA by RT-PCR in the peripheral blood of patients with advanced metastatic melanoma. Melanoma Res., 9: 395-399, 1999.
25. Kopreski, M. S., Benko, F. A., Kwak, L. W., and Gocke, C. D. Detection of tumor messenger RNA in the serum of patients with malignant melanoma. Clin. Cancer Res., 5: 1961-1965, 1999.
26. Proebstle, T. M., Jiang, W., Högel, J., Keilholz, U., Weber, L., and Voit, C. Correlation of positive RT-PCR for tyrosinase in peripheral blood of malignant melanoma patients with clinical stage, survival and other risk factors. Br. J. Cancer, 82: 118-123, 2000.
27. Johansson, M., Arstrand, K., Hakansson, A., Lindholm, C., and Kagedal, B. Quantitative analysis of tyrosinase and tyrosinase-related protein-2 mRNA from melanoma cells in blood by real-time polymerase chain reaction. Melanoma Res., 10: 213-222, 2000.
28. Baldi, A., Dragonetti, E., Battista, T., Groeger, A. M., Esposito, V., Baldi, G., and Santini, D. Detection of circulating malignant cells by RT-PCR in long-term clinically disease-free I Stage melanoma patients. Anticancer Res., 20: 3923-3928, 2000.
29. Tsukamoto, K., Ueda, M., Hirata, S., Osada, A., Kitamura, R., Takahashi, T., Ichihashi, M., and Shimada, S. gp100 mRNA is more sensitive than tyrosinase mRNA for RT-PCR amplification to detect circulating melanoma cells in peripheral blood of melanoma patients. J. Dermatol. Sci., 23: 126-131, 2000.
30. Abate, S. O., Savoia, P., Cambieri, I., Salomone, B., Quaglino, P., and Bernengo, M. G. Role of the RT-PCR tyrosinase detection in the monitoring of patients with advanced metastatic melanoma. Melanoma Res., 10: 545-555, 2000.
31. Reinhold, U., Berkin, C., Bosserhoff, A. K., Deutschmann, A., Garbe, C., Glaser, R., Hein, R., Krahn, G., Peter, R. U., Rappl, G., Schittek, B., Seiter, S., Ugurel, S., Volkenandt, M., and Tilgen, W. Interlaboratory evaluation of a new reverse transcriptase polymerase chain reaction-based enzyme-linked immunosorbent assay for the detection of circulating melanoma cells: a multicenter study of the Dermatologic Cooperative Oncology Group. J. Clin. Oncol., 19: 1723-1727, 2001.
32. Blaheta, H. J., Paul, T., Sotlar, K., Maczey, E., Schittek, B., Paul, A., Moehrle, M., Breuninger, H., Bueltmann, B., Rassner, G., and Garbe, C. Detection of melanoma cells in sentinel lymph nodes, bone marrow and peripheral blood by a reverse transcription-polymerase chain reaction assay in patients with primary cutaneous melanoma: association with Breslow's tumour thickness. Br. J. Dermatol., 145: 195-202, 2001.
33. Strohal, R., Mosser, R., Kittler, H., Wolff, K., Jansen, B., Brna, C., Stingl, G., and Pehamberger, H. MART-1/Melan-A and tyrosinase transcripts in peripheral blood of melanoma patients: PCR analyses and folow-up testing in relation to clinical stage and disease progression. Melanoma Res., 11: 543-548, 2001.
34. Stoitchkov, K., Letellier, S., Gamier, J. P., Toneva, M., Naumova, E., Peytcheva, E., Tzankov, N., Bousquet, B., Morel, P., and Le Bricon, T. Evaluation of standard tyrosinase RT-PCR in melanoma patients by the use of the Light Cycler system. Clin. Chim. Acta, 306: 133-138, 2001.
35. Hasselmann, D. O., Rappl, G., Rössler, M., Ugurel, S., Tilgen, W., and Reinhold, U. Detection of tumor-associated circulating mRNA in serum, plasma and blood cells from patients with disseminated malignant melanoma. Oncol. Rep., 8: 115-118, 2001.
36. Brownbridge, G. G., Gold, J., Edward, M., and MacKie, R. M. Evaluation of the use of tyrosinase-specific and MelanA/MART-1-specific reverse transcriptase-coupled-polymerase chain reaction to detect melanoma cells in peripheral blood samples from 299 patients with malignant melanoma. Br. J. Dermatol., 144: 279-287, 2001.
37. Burchill, S. A., Perebolte, L., Johnston, C., Top, B., and Selby, P. Comparison of the RNA-amplification based methods RT-PCR and NASBA for the detection of circulating tumour cells. Br. J. Cancer, 86: 102-109, 2002.
38. Mellado, B., Del Carmen Vela, M., Colomer, D., Gutierrez, L., Castel, T., Quinto, L., Fontanillas, M., Reguart, N., Domingo-Domenech, J. M., Montagut, C., Estape, J., and Gascon, P. Tyrosinase mRNA in blood of patients with melanoma treated with adjuvant interferon. J. Clin. Oncol., 20: 4032-4039, 2002.
39. Keilholz, U., Willhauck, M., Rimoldi, D., Brasseur, F., Dummer, W., Rass, K., de Vries, T., Blaheta, J., Voit, C., Lethe, B., and Burchill, S. Reliability of reverse transcription-polymerase chain reaction (RT-PCR)-based assays for the detection of circulating tumour cells: a quality-assurance initiative of the EORTC Melanoma Cooperative Group. Eur. J. Cancer, 34: 750-753, 1998.
40. Max, N., Willhauck, M., Wolf, K., Thilo, F., Reinhold, U., Pawlita, M., Thiel, E., and Keilholz, U. Reliability of PCR-based detection of occult tumour cells: lessons from real-time RT-PCR. Melanoma Res., 11: 371-378, 2001.
41. Balch, C. M., Buzaid, A. C., Soong, S-J., Atkins, M. B., Cascinelli, N., Coit, D. G., Fleming, I. D., Gershenwald, J. E., Houghton, A., Jr., Kirkwood, J. M., McMasters, K. M., Mihm, M. F., Morton, D. L., Reintgen, D. S., Ross, M. I., Sober, A., Thompson, J. A., and Thompson, J. F. Final version of the American Joint Committee on Cancer Staging System for Cutaneous Melanoma. J. Clin. Oncol., 19: 3635-3648, 2001.
42. Chomczynski, P., and Sacchi, N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162: 156-159, 1987.
43. Keilholz, U., Willhauck, M., Scheibenbogen, C., de Vries, T. J., and Burchill, S. Polymerase chain reaction detection of circulating tumour cells. Melanoma Res., 7: S133-S141, 1997.
44. Valentine-Thon, E., van Loon, A. M., Schirm, J., Reid, J., Klapper, P. E., and Cleator, G. M. European proficiency testing program for molecular detection and quantitation of hepatitis B virus DNA. J. Clin. Microbiol., 39: 4407-4412, 2001.
45. van Dongen, J. J. M., Macintyre, E. A., Gabert, J. A., Delabesse, E., Rossi, V., Saglio, G., Gottardi, E., Rambaldi, A., Dotti, G., Griesinger, F., Parreira, A., Gameiro, P., Gonzalez Diaz, M., Malec, M., Langerak, A. W., San Miguel, J. F., and Biondi, A. Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Leukemia (Baltimore), 13: 1901-1928, 1999.
46. Bolufer, P., Lo Coco, F., Grimwade, D., Barragan, E., Diverio, D., Cassinat, B., Chomienne, C., Gonzalez, M., Colomer, D., Gomez, M-T., Marugan, I., Roman, J., Delgado, M-D., Garcia-Marco, J-A., Bornstein, R., Vizmanos, J-L., Martinez, B., Jansen, J., Villegas, A., De Blas, J-M., Cabello, P., and Sanz, M-A. Variability in the levels of PML-RARα fusion transcripts detected by laboratories participating in an external quality control program using several reverse transcription polymerase chain reaction protocols. Haematologica, 86: 570-576, 2001.
47. Singh, A. D., Shields, C. L., and Shields, J. A. Prognostic factors in uveal melanoma. Melanoma Res., 11: 255-265, 2001.
48. Makitie, T., Summanen, P., Tarkkanen, A., and Kivala, T. Microvascular density in predicting survival of patients with choroidal and ciliary body melanoma. Investig. Ophthalmol. Vis. Sci., 40: 2471-2480, 1999.