N-acetyltransferase 2 and glutathione S-transferase M1 in colon and rectal cancer cases from an industrialized area

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 75, Issue 8-10, 2012, Pages 572-581

  Golka, Klaus ^a   Roemer, Hermann C ^a,b,c   Weistenhöfer, Wobbeke ^a,d   Blaszkewicz, Meinolf ^a   Hammad, Seddik ^a,e   Reckwitz, Thomas ^b   Loehlein, Dietrich ^b   Hartel, Mark ^b   Hengstler, Jan G ^a   Geller, Frank ^f  

^a LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

^b KLINIKUM DORTMUND   (Germany)

^c UNIVERSITY HOSPITAL ESSEN   (Germany)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^e South Valley University   (Egypt)

^f STATENS SERUM INSTITUT   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLAMINE ACETYLTRANSFERASE; GLUTATHIONE TRANSFERASE M1;

AGED; ARTICLE; ASCENDING COLON; CANCER RISK; COLON CANCER; CONTROLLED STUDY; FEMALE; GENOTYPE; HUMAN; INDUSTRIAL AREA; MAJOR CLINICAL STUDY; MALE; MANUAL LABOR; METAL INDUSTRY; NUTRITION; OCCUPATIONAL HAZARD; PAINTER; PHENOTYPE; PHYSICAL ACTIVITY; PILOT STUDY; PRIORITY JOURNAL; RECTUM CANCER;

AGED; ALCOHOL DRINKING; ARYLAMINE N-ACETYLTRANSFERASE; CASE-CONTROL STUDIES; COAL; COLONIC NEOPLASMS; FEMALE; GENE FREQUENCY; GENOTYPE; GERMANY; GLUTATHIONE TRANSFERASE; HUMANS; INDUSTRY; IRON; MALE; MOTOR ACTIVITY; OCCUPATIONAL EXPOSURE; PAINTINGS; RECTAL NEOPLASMS; RISK FACTORS; SEX FACTORS; SMOKING; STEEL;

EID: 84862576919     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287394.2012.675310     Document Type: Article

References (64)

1. Agúndez, J. A. 2008. Polymorphisms of human N-acetyltransferases and cancer risk. Curr. Drug Metab. 9: 520-31.
2. Agúndez, J. A. G., Lozano, L., Ladero, J. M., Sastre, J., Cerdan, F. J., Diaz-Rubio, M., and Benitez, J. 2000. N-Acetyltransferase 2 (NAT2) genotype and colorectal carcinoma: Risk variability according to tumour side? Scand. J. Gastroenterol. 10: 1087-91.
3. Azimuddin, K., Khubchandani, I. T., Stasik, J. J., Rosen, L., and Riether, R. D. 1999. Neoplasia after ureterosigmoidostomy. Dis. Colon Rectum 42: 1632-38.
4. Badawi, A. F., Stern, S. J., Lang, N. P., and Kadlubar, F. F. 1996. Cytochrome P-450 and acetyltransferase expression as biomarkers of carcinogen-DNA adduct levels and human cancer susceptibility. Prog. Clin. Biol. Res. 395:109-40.
5. Bolt, H. M., and Golka, K. 2012. 1,3-Propane sultone as an extremely potent human carcinogen: Description of an exposed cohort in Germany. J. Toxicol. Environ. Health A 758-10:
6. Bolt, H. M., Selinski, S., Dannappel, D., Blaszkewicz, M., and Golka, K. 2005. Reinvestigation of the concordance of human NAT2 phenotypes and genotypes. Arch. Toxicol. 79:196-200.
7. Bolt, H. M., and Thier, R. 2006. Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicology. Curr. Drug Metab. 7:613-28.
8. Botteri, E., Iodice, S., Bagnardi, V., Raimondi, S., Lowenfels, A. B., and Maisonneuve, P. 2008. Smoking and colorectal cancer: A meta-analysis. J. Am. Med. Assoc. 300: 2765-78.
9. Bountziouka, V., and Panagiotakos, D. B. 2010. Statistical methods used for the evaluation of reliability and validity of nutrition assessment tools used in medical research. Curr. Pharm. Design 16: 3770-75.
10. Calvert, G. M., Ward, E., Schnorr, T. M., and Fine, L. J. 1998. Cancer risks among workers exposed to metalworking fluids: a systematic review. Am. J. Ind. Med. 33: 282-92.
11. Carlsten, C., Sagoo, G. S., Frodsham, A. J., Burke, W., and Higgins, J. P. 2008. Glutathione S-transferase M1 (GSTM1) polymorphisms and lung cancer: A literature-based systematic HuGE review and meta-analysis. Am. J. Epidemiol. 167: 759-74.
12. Chen, K., Jiang, Q. T., and He, H. Q. 2005. Relationship between metabolic enzyme polymorphism and colorectal cancer. World J. Gastroenterol. 11: 331-35.
13. Clapp, R. W., Jacobs, M. M., and Loechler, E. L. 2007. Environmental and occupational causes of cancer. New evidence 2005-2007. Lowell, MA: Lowell Center for Sustainable Production, University of Massachusetts.
14. Corpet, D. E. 2011. Red meat and colon cancer: Should we become vegetarians, or can we make meat safer? Meat Sci. 89: 310-16.
15. Cotton, S. C., Sharp, L., Little, J., and Brockton, N. 2000. Glutathione S-transferase polymorphisms and colorectal cancer: A HuGE review. Am. J. Epidemiol. 151: 7-32.
16. Economopoulos, K. P., and Sergentanis, T. N. 2010. GSTM1, GSTT1, GSTP1, GSTA1 and colorectal cancer risk: A comprehensive meta-analysis. Eur. J. Cancer 46: 1617-31.
17. Epidemiologisches Krebsregister Nordrhein-Westfalen. 2011. http://www.krebsregister.nrw.de (accessed August 16, 2011).
18. Fichtner, J. 1999. Follow-up after urinary diversion. Urol. Int. 63: 40-45.
19. Friesen, M. C., Costello, S., and Eisen, E. A. 2009. Quantitative exposure to metalworking fluids and bladder cancer incidence in a cohort of autoworkers. Am. J. Epidemiol. 169: 1471-78.
20. Gao, Y., Cao, Y., Tan, A., Liao, C., Mo, Z., and Gao, F. 2010. Glutathione S-transferase M1 polymorphism and sporadic colorectal cancer risk: An updating meta-analysis and HuGE review of 36 case-control studies. Ann. Epidemiol. 20: 108-21.
21. Ginsberg, G., Smolenski, S., Hattis, D., Guyton, K. Z., and Sonawane, B. 2009. Genetic polymorphism in glutathione transferases (GST). Population distribution of GSTM1, T1 and P1 conjugating activity. J. Toxicol. Environ. Health B 12: 389-439.
22. Golka, K., Bandel, T., Schlaefke, S., Reich, S. E., Reckwitz, T., Urfer, W., Bremicker, K.-D., Neugebauer, W., Soekeland, J., and Bolt H. M. 1998. Urothelial cancer of the bladder in an area of former coal, iron, and steel industries in Germany: A case-control study. Int. J. Occup. Environ. Health 4: 79-84.
23. Golka, K., Hermes, M., Selinski, S., Blaszkewicz, M., Bolt, H. M., Roth, G., Dietrich, H., Prager, H. M., Ickstadt, K., and Hengstler, J. G. 2009. Susceptibility to urinary bladder cancer: Relevance of rs9642880[T], GSTM1 0/0 and occupational exposure. Pharmacogenet. Genomics 19: 903-6.
24. Golka, K., Reckwitz, T., Kempkes, M., Cascorbi, I., Blaszkewicz, M., Reich, S. E., Roots, I., Sökeland, J., Schulze, H., and Bolt, H. M. 1997. N-Acetyltransferase 2 (NAT2) and glutathione S-transferase μ (GSTM1) in bladder-cancer patients in a highly industrialized area. Int. J. Occup. Environ. Health 3: 105-10.
25. Gosetti, F., Chiuminatto, U., Mazzucco, E., Robotti, E., Calabrese, G., Gennaro, M. C., and Marengo, E. 2011. Simultaneous determination of thirteen polycyclic aromatic hydrocarbons and twelve aldehydes in cooked food by an automated online solid phase extraction ultra high performance liquid chromatography tandem mass spectrometry. J. Chromatogr. A 1218: 6408-18.
26. Hamilton, S. R., and Aaltonen, L. A., eds. 2000. World Health Organization classification of tumours. Pathology and genetics of tumours of the digestive system. Lyon: IARC Press.
27. Hampel, H., Frankel, W. L., Martin, E., Arnold, M., Khanduja, K., Kuebler, P., Nakagawa, H., Sotamaa, K., Prior, T. W., Westman, J., Panescu, J., Fix, D., Lockman, J., Comeras, I., and de la Chapelle, A. 2005. Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer). N. Engl. J. Med. 352: 1851-60.
28. Hayes, J. D., and Pulford, D. J. 1995. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit. Rev. Biochem. Mol. Biol. 30: 445-600.
29. Hengstler, J. G., Arand, M., Herrero, M. E., and Oesch, F. 1998. Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility. Recent Results Cancer Res. 154: 47-85.
30. Hoensch, H., Peters, W. H., Roelofs, H. M., and Kirch, W. 2006. Expression of the glutathione enzyme system of human colon mucosa by localisation, gender and age. Curr. Med. Res. Opin. 22: 1075-83.
31. Ilett, K. F., David, B. M., Detchon, P., Castleden, W. M., and Kwa, R. 1987. Acetylation phenotype in colorectal carcinoma. Cancer Res. 47: 1466-69.
32. Innos, K., Rahu, M., Rahu, K., Lang, I., and Leon, D. A. 2000. Wood dust exposure and cancer incidence: A retrospective cohort study of furniture workers in Estonia. Am. J. Ind. Med. 37: 501-11.
33. Jass, J. R., Do, K. A., Simms, L. A., Iino, H., Wynter, C., Pillay, S. P., Searle, J., Radford-Smith, G., Young, J., and Leggett, B. 1998. Morphology of sporadic colorectal cancer with DNA replication errors. Gut 42: 673-79.
34. Kempkes, M., Golka, K., Reich, S., Reckwitz, T., and Bolt, H. M. 1996. Glutathione S-transferase GSTM1 and GSTT1 null genotypes as potential risk factors for urothelial cancer of the bladder. Arch. Toxicol. 71: 123-26.
35. Kühnel, D., Taugner, F., Scholtka, B., and Steinberg, P. 2009. Inflammation does not precede or accompany the inductionof preneoplastic lesions in the colon of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-fed rats. Arch. Toxicol. 83: 763-68.
36. Ladero, J. M., Gonzáles, J. F., Benítez, J., Vargas, E., Fernández, M. J., Baki, W., and Diaz-Rubio, M. 1991. Acetylator polymorphism in human colorectal carcinoma. Cancer Res. 51: 2098-100.
37. Lang, N. P., Chu, D. Z., Hunter, C. F., Kendall, D. C., Flammang, T. J., and Kadlubar, F. F. 1986. Role of aromatic amine acetyltransferase in human colorectal cancer. Arch. Surg. 121: 1259-61.
38. Lang, N. P., and Kadlubar, F. F. 1991. Aromatic and heterocyclic amine metabolism and phenotyping in humans. Prog. Clin. Biol. Res. 372: 33-47.
39. Malloy, E. J., Miller, K. L., and Eisen, E. A. 2007. Rectal cancer and exposure to metalworking fluids in the automobile manufacturing industry. Occup. Environ. Med. 64: 244-49.
40. Moradi, T., Gridley, G., Björk, J., Dosemeci, M., Ji, B. T., Berkel, H. J., and Lemeshow, S. 2008. Occupational physical activity and risk for cancer of the colon and rectum in Sweden among men and women by anatomic subsite. Eur. J. Cancer Prev. 17: 201-8.
41. Pesch, B., Halekoh, U., Ranft, U., Richter, M., and Pott, F. 1994. Atlas zur Krebssterblichkeit NRW. Düsseldorf, Germany: Ministerium für Arbeit, Gesundheit und Soziales NRW.
42. Raimondi, S., Botteri, E., Iodice, S., Lowenfels, A. B., and Maisonneuve, P. 2009. Gene-smoking interaction on colorectal adenoma and cancer risk: Review and meta-analysis. Mutat. Res. 670: 6-14.
43. Rashid, A., Zahurak, M., Goodman, S. N., and Hamilton, S. R 1999. Genetic epidemiology of mutated K-ras proto-oncogene, altered suppressor genes, and microsatellite instability in colorectal adenomas. Gut 44: 826-33.
44. Robert Koch Institute and Association of Population-based Cancer Registries in Germany, eds. 2010. Cancer in Germany 2005/2006. Incidence and trends, 7th ed. Berlin, Germany: Authors.
45. Roberts-Thomson, I. C., Ryan, P., Khoo, K. K., Hart, W. J., McMichael, A. J., and Butler, R. N. 1996. Diet, acetylator phenotype, and risk of colorectal neoplasia, Lancet 347: 1372-74.
46. Roemer, H. C., Weistenhöfer, W., Löhlein, D., Geller, F., Blömeke, B., and Golka, K. 2008. N-Acetyltransferase 1 in colon and rectal cancer cases from an industrialized area. J. Toxicol. Environ. Health A 71: 902-5.
47. Rohrmann, S., Hermann, S., and Linseisen, J. 2009. Heterocyclic aromatic amine intake increases colorectal adenoma risk: Findings from a prospective European cohort study. Am. J. Clin. Nutr. 89: 1418-24.
48. Roscoe, R. J., Steenland, K., McCammon, C. S. Jr., Schrober, S. E., Robinson, C. F., Halperin, W. E., and Fingerhut, M. A. 1992. Colon and stomach cancer mortality among automotive wood model makers. J. Occup. Med. 34: 759-68; discussion 769-70.
49. Rothman, N., Garcia-Closas, M., Chatterjee, N., Malats, N., Wu, X., Figueroa, J. D., Real, F. X., Van Den Berg, D., Matullo, G., Baris, D., Thun, M., Kiemeney, L. A., Vineis, P., De Vivo, I., Albanes, D., Purdue, M. P., Rafnar, T., Hildebrandt, M. A., Kiltie, A. E., Cussenot, O., Golka, K., Kumar, R., Taylor, J. A., Mayordomo, J. I., Jacobs, K. B., Kogevinas, M., Hutchinson, A., Wang, Z., Fu, Y. P., Prokunina-Olsson, L., Burdett, L., Yeager, M., Wheeler, W., Tardón, A., Serra, C., Carrato, A., García-Closas, R., Lloreta, J., Johnson, A., Schwenn, M., Karagas, M. R., Schned, A., Andriole, G., Jr., Grubb, R. 3rd, Black, A., Jacobs, E. J., Diver, W. R., Gapstur, S. M., Weinstein, S. J., Virtamo, J., Cortessis, V. K., Gago-Dominguez, M., Pike, M. C., Stern, M. C., Yuan, J. M., Hunter, D. J., McGrath, M., Dinney, C. P., Czerniak, B., Chen, M., Yang, H., Vermeulen, S. H., Aben, K. K., Witjes, J. A., Makkinje, R. R., Sulem, P., Besenbacher, S., Stefansson, K., Riboli, E., Brennan, P., Panico, S., Navarro, C., Allen, N. E., Bueno-de-Mesquita, H. B., Trichopoulos, D., Caporaso, N., Landi, M. T., Canzian, F., Ljungberg, B., Tjonneland, A., Clavel-Chapelon, F., Bishop, D. T., Teo, M. T., Knowles, M. A., Guarrera, S., Polidoro, S., Ricceri, F., Sacerdote, C., Allione, A., Cancel-Tassin, G., Selinski, S., Hengstler, J. G., Dietrich, H., Fletcher, T., Rudnai, P., Gurzau, E., Koppova, K., Bolick, S. C., Godfrey, A., Xu, Z., Sanz-Velez, J. I., García-Prats, M. D., Sanchez, M., Valdivia, G., Porru S., Benhamou S., Hoover, R. N., Fraumeni, J. F. Jr, Silverman, D. T., and Chanock, S. J. 2010. A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat. Genet. 42: 978-83.
50. Simpson, C. L., Garabrant, D. H., Fryzek, J., Homa, D. M., and Peters, R. K. 1998. Wooddust exposures and cancer of the colon. Int. J. Occup. Environ. Health 4: 179-83.
51. Sinha, R., Peters, U., Cross, A. J., Kulldorff, M., Weissfeld, J. L., Pinsky, P. F., Rothman, N., and Hayes, R. B. 2005. Meat, meat cooking methods and preservation, and risk for colorectal adenoma. Cancer Res. 65: 8034-41.
52. Smits, K. M., Gaspari, L., Weijenberg, M. P., Dolzan, V., Golka, K., Roemer, H. C., Nedelcheva Kristensen, V., Lechner, M. C., Mehling, G. I., Seidegard, J., Strange, R. C., and Taioli, E. 2003. Interaction between smoking, GSTM1 deletion and colorectal cancer: Results from the GSEC study. Biomarkers 8: 299-310.
53. Sugimura, T., Wakabayashi, K., Nakagama, H., and Nagao, M. 2004. Heterocyclic amines: Mutagens/carcinogens produced during cooking of meat and fish. Cancer Sci. 95: 290-99.
54. Statistisches Bundesamt (Hrsg.). 1992. Klassifizierung der Berufe. Systematisches und alphabetisches Verzeichnis der Berufsbenennungen. Stuttgart, Germany: Metzler-Poeschel-Verlag.
55. 'tMannetje, A., McLean, D., Cheng, S., Boffetta, P., Colin, D., and Pearce, N. 2005. Mortality in New Zealand workers exposed to phenoxy herbicides and dioxins. Occup. Environ. Med. 62: 34-40.
56. Tang, W. Y., Elnatan, J., Lee, Y. S., Goh, H. S., and Smith, D. R. 1999. c-Ki-ras mutations in colorectal adenocarcinomas from a country with a rapidly changing colorectal cancer incidence. Br. J. Cancer 81: 237-41.
57. Thier, R., Brüning, T., Roos, P. H., Rihs, H. P., Golka, K., Ko, Y., and Bolt, H. M. 2003. Markers of genetic susceptibility in human environmental hygiene and toxicology: The role of selected CYP, NAT and GST genes. Int. J. Hyg. Environ. Health 206: 149-71.
58. Thomas, R. M., and Sobin, L. H. 1995. Gastrointestinal cancer. Cancer 75: 154-70.
59. Turesky, R. J., Lang, N. P., Butler, M. A., Teitel, C. H., and Kadlubar, F. F. 1991. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon. Carcinogenesis 12: 1839-45.
60. Walker, K., Ginsberg, G., Hattis, D., Johns, D. O., Guyton, K. Z. and Sonawane, B. 2009. Genetic polymorphism in N-acetyltransferase (NAT): Population distribution of NAT 1 and NAT 2 activity. J. Toxicol. Environ. Health B 12: 440-72.
61. World Cancer Research Fund and American Institute for Cancer Research. 2007. Food, nutrition, physical activity, and the prevention of cancer: A global perspective. Washington, DC: WCRF and AICR.
62. Ye, Z., and Parry, J. M. 2002. Meta-analysis of 20 case-control studies on the N-acetyltransferase 2 acetylation status and colorectal cancer risk. Med. Sci. Monit. 8: CR558-65.
63. Zhang, Y., Cantor, K. P., Dosemeci, M., Lynch, C. F., Zhu, Y., and Zheng, T. 2006 Occupational and leisure-time physical activity and risk of colon cancer by subsite. J. Occup. Environ. Med. 48: 236-43.
64. Zheng, W., and Lee, S. A. 2009. Well-done meat intake, heterocyclic amine exposure, and cancer risk. Nutr. Cancer 61: 437-46.