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Volumn 33, Issue 21, 2012, Pages 1740-1747

Metabolic-intermediate complex formation with cytochrome P450: Theoretical studies in elucidating the reaction pathway for the generation of reactive nitroso intermediate

Author keywords

density functional theory; mechanism based inhibition of cytochrome P450; metabolic intermediate complex with cytochrome P450; nitroso intermediate; reaction mechanism

Indexed keywords

AROMATIC AMINES; AXIAL LIGAND; B3LYP METHOD; BIOTRANSFORMATION PROCESS; BIOTRANSFORMATION REACTIONS; CATALYTIC DOMAINS; COMPLEX FORMATIONS; CYTOCHROME P450; DENSITY FUNCTIONALS; DRUG-DRUG INTERACTIONS; ENERGY PROFILE; EXOTHERMIC PROCESS; H-ABSTRACTION; HEME IRON; N-OXIDATION; NITROSO; PORPHINE; POTENTIAL REACTIONS; PRIMARY AMINES; PROTON SHUTTLE; QUANTUM CHEMICAL ANALYSIS; RATE DETERMINING STEP; REACTION MECHANISM; REACTION PATHS; REACTION PATHWAYS; REACTIVE INTERMEDIATE; REACTIVE METABOLITES; SPIN DENSITIES; SPIN SURFACES; THEORETICAL STUDY; THREE-DIMENSIONAL STRUCTURE; TRANSITION STATE;

EID: 84862560091     PISSN: 01928651     EISSN: 1096987X     Source Type: Journal    
DOI: 10.1002/jcc.23008     Document Type: Article
Times cited : (32)

References (43)
  • 3
    • 0001842796 scopus 로고
    • In; R. B. Silverman, Ed.; CRC Press: Boca Raton
    • R. B. Silverman, In Chemistry and Enzymology;, R. B. Silverman, Ed.; CRC Press: Boca Raton, 1988, pp. 3-30.
    • (1988) Chemistry and Enzymology , pp. 3-30
    • Silverman, R.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.