Regulated expression of pH sensing G protein-coupled receptor-68 identified through chemical biology defines a new drug target for ischemic heart disease

ACS Chemical Biology

Volumn 7, Issue 6, 2012, Pages 1077-1083

  Russell, Jamie L ^a   Goetsch, Sean C ^a   Aguilar, Hector R ^b   Coe, Helen ^a   Luo, Xiang ^a   Liu, Ning ^a   Van Rooij, Eva ^a   Frantz, Doug E ^b   Schneider, Jay W ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 68; ISOXAZOLE DERIVATIVE; MESSENGER RNA; MITOCHONDRIAL RNA; NOTCH RECEPTOR; PROTON; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DEVELOPMENT; DRUG SCREENING; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC GAIN; GENETIC TRANSCRIPTION; HEART INFARCTION; HEART MUSCLE CELL; IN VIVO STUDY; ISCHEMIC HEART DISEASE; LOSS OF FUNCTION MUTATION; MOUSE; NONHUMAN; PERINATAL PERIOD; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; REGULATORY MECHANISM;

ANIMALS; CALCIUM; CELL LINE; CELLS, CULTURED; ISOXAZOLES; MICE; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; PERICARDIUM; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NOTCH; TRANSCRIPTIONAL ACTIVATION;

EID: 84862552061     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb300001m     Document Type: Article

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